Kevin Zhang
@kyzhang.bsky.social
Neuropathology trainee @JHU studying brain metastasis with @ashi-w.bsky.social
Reposted by Kevin Zhang
Are you using the right tumor micro environment model? Cancer is a disease of aging @sitcancer.bsky.social #SITC25 great session at the annual meeting on the aged immune system and the tumor micro environment moderated by Drs DA and A Weeraratna.
November 7, 2025 at 9:28 PM
Are you using the right tumor micro environment model? Cancer is a disease of aging @sitcancer.bsky.social #SITC25 great session at the annual meeting on the aged immune system and the tumor micro environment moderated by Drs DA and A Weeraratna.
Reposted by Kevin Zhang
How to disconnect therapy-resistant tumor networks in glioblastoma?
In our paper, online @Cancer Discovery, we built an anti-tumor microtube (TM) screening pipeline and found that Protein Kinase C activators disrupt TMs, silence Ca²⁺ “pacemakers” and boost radiotherapy.
doi.org/10.1158/2159...
In our paper, online @Cancer Discovery, we built an anti-tumor microtube (TM) screening pipeline and found that Protein Kinase C activators disrupt TMs, silence Ca²⁺ “pacemakers” and boost radiotherapy.
doi.org/10.1158/2159...
October 9, 2025 at 8:52 PM
How to disconnect therapy-resistant tumor networks in glioblastoma?
In our paper, online @Cancer Discovery, we built an anti-tumor microtube (TM) screening pipeline and found that Protein Kinase C activators disrupt TMs, silence Ca²⁺ “pacemakers” and boost radiotherapy.
doi.org/10.1158/2159...
In our paper, online @Cancer Discovery, we built an anti-tumor microtube (TM) screening pipeline and found that Protein Kinase C activators disrupt TMs, silence Ca²⁺ “pacemakers” and boost radiotherapy.
doi.org/10.1158/2159...
Reposted by Kevin Zhang
Review 🚨
Easwaran&Weeraratna outline how #ageing leads to epigenetic alterations in the #TME, enhancing clonal expansion of mutations and ultimately increasing cancer risk.
📖 👇
Easwaran&Weeraratna outline how #ageing leads to epigenetic alterations in the #TME, enhancing clonal expansion of mutations and ultimately increasing cancer risk.
📖 👇
Unravelling the genetics and epigenetics of the ageing tumour microenvironment in cancer - Nature Reviews Cancer
In this Review, Easwaran and Weeraratna outline how ageing leads to epigenetic alterations in the tissue microenvironment, enhancing clonal expansion of mutations and ultimately increasing cancer risk.
bit.ly
September 16, 2025 at 2:49 PM
Reposted by Kevin Zhang
In the United States, cases of early-onset cancer are on the rise. Featured in a recent #AACRBlog on early-onset cancer, this Cancer Discovery article explores how changes in risk factor prevalence and/or improvements in detection could affect risk across an age range. Read more: buff.ly/NLssp4H
August 8, 2025 at 4:04 PM
In the United States, cases of early-onset cancer are on the rise. Featured in a recent #AACRBlog on early-onset cancer, this Cancer Discovery article explores how changes in risk factor prevalence and/or improvements in detection could affect risk across an age range. Read more: buff.ly/NLssp4H
Reposted by Kevin Zhang
Hidden in the lungs of some breast cancer survivors are tumour cells that can remain dormant for decades — until they one day trigger a relapse
go.nature.com/41iIdJR
go.nature.com/41iIdJR
‘Sleeping’ cancer cells in the lungs can be roused by COVID and flu
Inflammation from the respiratory infections seems to be the culprit, study in mice finds.
go.nature.com
July 30, 2025 at 3:19 PM
Hidden in the lungs of some breast cancer survivors are tumour cells that can remain dormant for decades — until they one day trigger a relapse
go.nature.com/41iIdJR
go.nature.com/41iIdJR
Reposted by Kevin Zhang
Congratulations Dr. Alexis Carey! Alexis Carey is in the Cellular & Molecular Medicine program and successfully defended her PhD today. In today's seminar she shared her about work in the Weeraratna Lab on “Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment”
July 18, 2025 at 4:50 PM
Congratulations Dr. Alexis Carey! Alexis Carey is in the Cellular & Molecular Medicine program and successfully defended her PhD today. In today's seminar she shared her about work in the Weeraratna Lab on “Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment”
Reposted by Kevin Zhang
Listen to BDP @ashi-w.bsky.social discuss her work in #melanoma research on the Kimmel Cancer Center podcast, Cancer Matters.
hopkinskimmel.libsyn.com/cancer-matte...
hopkinskimmel.libsyn.com/cancer-matte...
Johns Hopkins Kimmel Cancer Center Podcasts: Cancer Matters with Dr Bill Nelson - Melanoma Research
Dr Bill Nelson talks with Dr Ashani Weeraratna about her work in melanoma research, the progress that has been made in treating patients with melanoma, and the importance of federal research funding i...
hopkinskimmel.libsyn.com
July 2, 2025 at 5:28 PM
Listen to BDP @ashi-w.bsky.social discuss her work in #melanoma research on the Kimmel Cancer Center podcast, Cancer Matters.
hopkinskimmel.libsyn.com/cancer-matte...
hopkinskimmel.libsyn.com/cancer-matte...
Reposted by Kevin Zhang
"No tumor is an island" and "oncology recapitulates embryology" - a fascinating conversation with the incredible @ashi-w.bsky.social at the CSHL symposium on aging.
We talk about how cancer rates increase with age, the T(I!)ME, and the role of Wnt signaling www.youtube.com/watch?v=_Txf...
We talk about how cancer rates increase with age, the T(I!)ME, and the role of Wnt signaling www.youtube.com/watch?v=_Txf...
Interview with Ashani Weeraratna
YouTube video by CSHL Leading Strand
www.youtube.com
May 30, 2025 at 12:01 AM
"No tumor is an island" and "oncology recapitulates embryology" - a fascinating conversation with the incredible @ashi-w.bsky.social at the CSHL symposium on aging.
We talk about how cancer rates increase with age, the T(I!)ME, and the role of Wnt signaling www.youtube.com/watch?v=_Txf...
We talk about how cancer rates increase with age, the T(I!)ME, and the role of Wnt signaling www.youtube.com/watch?v=_Txf...
Reposted by Kevin Zhang
This year’s 11 NextGen Stars will share their findings on cancer cartography, the dark proteome, cancer-resistant tissues, and more at #AACR25. Learn more about their work and its future implications on the #AACRBlog: www.aacr.org/blog/2025/04...
April 26, 2025 at 4:18 PM
This year’s 11 NextGen Stars will share their findings on cancer cartography, the dark proteome, cancer-resistant tissues, and more at #AACR25. Learn more about their work and its future implications on the #AACRBlog: www.aacr.org/blog/2025/04...
We explore the utility of an immunohistochemical panel consisting of Sox10, p16, and cyclin D1 in differentiating MAP kinase-activated low-grade gliomas from piloid gliosis.
#neuropath #pathsky
journals.lww.com/ajsp/fulltex...
#neuropath #pathsky
journals.lww.com/ajsp/fulltex...
Increased SOX10, p16, and Cyclin D1 Immunoreactivity... : The American Journal of Surgical Pathology
available stains, we hypothesize that a limited panel including SOX10, p16, and cyclin D1 may be useful in differentiating mitogen-activated protein (MAP) kinase-activated low-grade gliomas from piloi...
journals.lww.com
January 18, 2025 at 1:13 AM
We explore the utility of an immunohistochemical panel consisting of Sox10, p16, and cyclin D1 in differentiating MAP kinase-activated low-grade gliomas from piloid gliosis.
#neuropath #pathsky
journals.lww.com/ajsp/fulltex...
#neuropath #pathsky
journals.lww.com/ajsp/fulltex...
Reposted by Kevin Zhang
Congratulations to the new #AACR #TME working group Chair elect!!!
The one and only (best friend and colleague) @ashi-w.bsky.social
www.aacr.org/professional...
The one and only (best friend and colleague) @ashi-w.bsky.social
www.aacr.org/professional...
TME Working Group Chair-Elect Election Results
Congratulations to Ashani T. Weeraratna, PhDTME Working Group Chair-elect 2025-2026 Our thanks to Ashani T. Weeraratna, PhD, and Marina Pasca di Magliano, PhD, for standing for election, and to the TM...
www.aacr.org
December 11, 2024 at 10:56 PM
Congratulations to the new #AACR #TME working group Chair elect!!!
The one and only (best friend and colleague) @ashi-w.bsky.social
www.aacr.org/professional...
The one and only (best friend and colleague) @ashi-w.bsky.social
www.aacr.org/professional...
Reposted by Kevin Zhang
🧵Just in time for
: New research from the Venkataramani lab @CellCellPress
maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here: authors.elsevier.com/sd/article/S...
@ekinreyhan.bsky.social
@svenjaktetzlaff.bsky.social
1/15
: New research from the Venkataramani lab @CellCellPress
maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here: authors.elsevier.com/sd/article/S...
@ekinreyhan.bsky.social
@svenjaktetzlaff.bsky.social
1/15
December 6, 2024 at 11:18 PM
🧵Just in time for
: New research from the Venkataramani lab @CellCellPress
maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here: authors.elsevier.com/sd/article/S...
@ekinreyhan.bsky.social
@svenjaktetzlaff.bsky.social
1/15
: New research from the Venkataramani lab @CellCellPress
maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here: authors.elsevier.com/sd/article/S...
@ekinreyhan.bsky.social
@svenjaktetzlaff.bsky.social
1/15
Reposted by Kevin Zhang
Myxopapillary ependymoma grossly has a characteristic sausage-shaped appearance. Commonly found associated with the filum terminale, it has a fibrillary glial appearance in a myxoid background. Though previously categorized as CNS WHO grade 1, it is now considered grade 2 #pathsky #medsky #neuropath
November 11, 2024 at 7:59 PM
Myxopapillary ependymoma grossly has a characteristic sausage-shaped appearance. Commonly found associated with the filum terminale, it has a fibrillary glial appearance in a myxoid background. Though previously categorized as CNS WHO grade 1, it is now considered grade 2 #pathsky #medsky #neuropath
Reposted by Kevin Zhang
Among the Cancer-related Starter Packs currently available, I didn’t find one on Tumor Microenvironment.
Here, the list of who I found until now… If you want to be added, please reply below!
go.bsky.app/CtQMJyW
Here, the list of who I found until now… If you want to be added, please reply below!
go.bsky.app/CtQMJyW
November 19, 2024 at 1:02 PM
Among the Cancer-related Starter Packs currently available, I didn’t find one on Tumor Microenvironment.
Here, the list of who I found until now… If you want to be added, please reply below!
go.bsky.app/CtQMJyW
Here, the list of who I found until now… If you want to be added, please reply below!
go.bsky.app/CtQMJyW
Reposted by Kevin Zhang
November 9, 2024 at 5:07 PM
Reposted by Kevin Zhang
🧠 barriers & neurovasculature starter pack - please reply here if you are not on it yet & would like to be added 😊 go.bsky.app/RB6RXKy
November 15, 2024 at 3:30 AM
🧠 barriers & neurovasculature starter pack - please reply here if you are not on it yet & would like to be added 😊 go.bsky.app/RB6RXKy