Maria Gubbiotti, MD,PhD
@mariagoobs.bsky.social
Neuropathologist at MD Anderson Cancer Center 🧠🔬Amateur Equine Enthusiast 🦄
Opinions are my own and are not reflective of my employer nor are they medical advice
#medsky #pathsky #eqbsky 🐎 🦋
Opinions are my own and are not reflective of my employer nor are they medical advice
#medsky #pathsky #eqbsky 🐎 🦋
Reposted by Maria Gubbiotti, MD,PhD
Abstract deadline approaching quickly (Nov 7, 2025) for the international #cancerneuroscience #symposium happening in Feb 2026!! Check out registration (SO CHEAP for 3 days!), abstract, and award details here:
mdanderson.cloud-cme.com/course/cours...
mdanderson.cloud-cme.com/course/cours...
October 24, 2025 at 6:40 PM
Abstract deadline approaching quickly (Nov 7, 2025) for the international #cancerneuroscience #symposium happening in Feb 2026!! Check out registration (SO CHEAP for 3 days!), abstract, and award details here:
mdanderson.cloud-cme.com/course/cours...
mdanderson.cloud-cme.com/course/cours...
Come join us in pathology at @mdanderson.bsky.social ! A great opportunity with a fun and dynamic group! 🔬 #pathsky
October 22, 2025 at 4:00 PM
Come join us in pathology at @mdanderson.bsky.social ! A great opportunity with a fun and dynamic group! 🔬 #pathsky
October 1st, the start of one of my favorite months! One of my friends in IT made me this 3D printed brain 🧠 the spooky candies were a nice touch 🎃 #pathsky
October 2, 2025 at 12:00 AM
October 1st, the start of one of my favorite months! One of my friends in IT made me this 3D printed brain 🧠 the spooky candies were a nice touch 🎃 #pathsky
Reposted by Maria Gubbiotti, MD,PhD
Image of the Week!
Submitted by: Gabrielle Yeaney, M.D.
Directory Profile: www.pathologyoutlines.com/directory/ga...
Subspecialty: Neuropathology
Diagnosis: Normal pineal gland
#Pathology #PathologyOutlines #NeuroPath #PathSky
Submitted by: Gabrielle Yeaney, M.D.
Directory Profile: www.pathologyoutlines.com/directory/ga...
Subspecialty: Neuropathology
Diagnosis: Normal pineal gland
#Pathology #PathologyOutlines #NeuroPath #PathSky
June 25, 2025 at 6:05 PM
Image of the Week!
Submitted by: Gabrielle Yeaney, M.D.
Directory Profile: www.pathologyoutlines.com/directory/ga...
Subspecialty: Neuropathology
Diagnosis: Normal pineal gland
#Pathology #PathologyOutlines #NeuroPath #PathSky
Submitted by: Gabrielle Yeaney, M.D.
Directory Profile: www.pathologyoutlines.com/directory/ga...
Subspecialty: Neuropathology
Diagnosis: Normal pineal gland
#Pathology #PathologyOutlines #NeuroPath #PathSky
Dural-based mass with dural tail
Negative for SSTR2, no evidence of STAT6 fusion, and strong CD56 staining
GLI1 amplification present
🧠 take home point: GLI1-altered mesenchymal tumors can occur in the CNS and radiologically mimic meningioma!
academic.oup.com/jnen/advance...
#pathsky
Negative for SSTR2, no evidence of STAT6 fusion, and strong CD56 staining
GLI1 amplification present
🧠 take home point: GLI1-altered mesenchymal tumors can occur in the CNS and radiologically mimic meningioma!
academic.oup.com/jnen/advance...
#pathsky
June 13, 2025 at 6:39 PM
Dural-based mass with dural tail
Negative for SSTR2, no evidence of STAT6 fusion, and strong CD56 staining
GLI1 amplification present
🧠 take home point: GLI1-altered mesenchymal tumors can occur in the CNS and radiologically mimic meningioma!
academic.oup.com/jnen/advance...
#pathsky
Negative for SSTR2, no evidence of STAT6 fusion, and strong CD56 staining
GLI1 amplification present
🧠 take home point: GLI1-altered mesenchymal tumors can occur in the CNS and radiologically mimic meningioma!
academic.oup.com/jnen/advance...
#pathsky
Reposted by Maria Gubbiotti, MD,PhD
MD Anderson research findings suggest that targeting interactions between some cells around the blood vessels could help make glioblastoma more vulnerable to treatment.
Read more: http://spr.ly/633204H8Uj #OncSky #EndCancer
Read more: http://spr.ly/633204H8Uj #OncSky #EndCancer
Targeting cells that form blood vessels in glioblastoma could improve treatment
Targeting cells that form blood vessels in glioblastoma could improve treatment
spr.ly
June 9, 2025 at 9:00 PM
MD Anderson research findings suggest that targeting interactions between some cells around the blood vessels could help make glioblastoma more vulnerable to treatment.
Read more: http://spr.ly/633204H8Uj #OncSky #EndCancer
Read more: http://spr.ly/633204H8Uj #OncSky #EndCancer
Reposted by Maria Gubbiotti, MD,PhD
📣TOMORROW, Friday, April 18, 12 noon CST!📣
Join the Brain Tumor Center of the Cancer Neuroscience Program seminar series! 🧠
We’re talking liquid biopsies in CNS tumors with @MDAnderson.bdky.social pathologist Dr. Leomar Ballester.
Login details: Email tpmarin@mdanderson.org
Join the Brain Tumor Center of the Cancer Neuroscience Program seminar series! 🧠
We’re talking liquid biopsies in CNS tumors with @MDAnderson.bdky.social pathologist Dr. Leomar Ballester.
Login details: Email tpmarin@mdanderson.org
April 17, 2025 at 9:42 PM
📣TOMORROW, Friday, April 18, 12 noon CST!📣
Join the Brain Tumor Center of the Cancer Neuroscience Program seminar series! 🧠
We’re talking liquid biopsies in CNS tumors with @MDAnderson.bdky.social pathologist Dr. Leomar Ballester.
Login details: Email tpmarin@mdanderson.org
Join the Brain Tumor Center of the Cancer Neuroscience Program seminar series! 🧠
We’re talking liquid biopsies in CNS tumors with @MDAnderson.bdky.social pathologist Dr. Leomar Ballester.
Login details: Email tpmarin@mdanderson.org
Superstar surgical pathology fellow Dr. William Mi was recognized with the Award for Clinical Excellence in Professionalism today! Congratulations to him for the well-deserved honor 🔬 #pathsky #medsky @mdanderson.bsky.social
April 4, 2025 at 7:52 PM
Superstar surgical pathology fellow Dr. William Mi was recognized with the Award for Clinical Excellence in Professionalism today! Congratulations to him for the well-deserved honor 🔬 #pathsky #medsky @mdanderson.bsky.social
Reposted by Maria Gubbiotti, MD,PhD
MD Anderson and Texas Children’s Hospital announce a transformational collaboration dedicated solely to pediatric cancer care. This new first-of-its-kind joint venture, which will launch in early 2026, has a single mission: to end childhood cancer. #EndCancer
UT MD Anderson and Texas Children’s Hospital Announce Joint Venture to End Childhood Cancer
bit.ly
February 19, 2025 at 10:42 PM
MD Anderson and Texas Children’s Hospital announce a transformational collaboration dedicated solely to pediatric cancer care. This new first-of-its-kind joint venture, which will launch in early 2026, has a single mission: to end childhood cancer. #EndCancer
In honor of upcoming Valentine’s Day here is a classic example of rosette-forming glioneuronal tumor. These grade 1 tumors typically show a hotspot mutation in FGFR1 along with PIK3R1 or PIK3CA alterations and are usually found in the fourth ventricle 🌹 ♥️ 🥀 🧠 🔬 #pathsky #neuropath #medsky
February 11, 2025 at 9:35 PM
In honor of upcoming Valentine’s Day here is a classic example of rosette-forming glioneuronal tumor. These grade 1 tumors typically show a hotspot mutation in FGFR1 along with PIK3R1 or PIK3CA alterations and are usually found in the fourth ventricle 🌹 ♥️ 🥀 🧠 🔬 #pathsky #neuropath #medsky
Reposted by Maria Gubbiotti, MD,PhD
#PathSky 43F with a solitary lung mass. Relatively circumscribed, nests and interesting micropapillae of lightly eosinophilic epithelioid cells. Negative for everything except TFE3. Dx?
February 6, 2025 at 9:41 PM
#PathSky 43F with a solitary lung mass. Relatively circumscribed, nests and interesting micropapillae of lightly eosinophilic epithelioid cells. Negative for everything except TFE3. Dx?
Reposted by Maria Gubbiotti, MD,PhD
This is a clear cell stromal tumor of the lung. They have YAP1::TFE3 fusions, which are also present in YAP1::TFE3-fused hemangioendotheliomas and some pulmonary PEComas. Abbas Agaimy described these. pubmed.ncbi.nlm.nih.gov/33899786/
Recurrent YAP1-TFE3 Gene Fusions in Clear Cell Stromal Tumor of the Lung - PubMed
Clear cell (hemangioblastoma-like) stromal tumor of the lung (CCST-L) is a recently described distinctive rare pulmonary neoplasm of unknown histogenesis and molecular pathogenesis. Only 7 cases have ...
pubmed.ncbi.nlm.nih.gov
February 6, 2025 at 9:44 PM
This is a clear cell stromal tumor of the lung. They have YAP1::TFE3 fusions, which are also present in YAP1::TFE3-fused hemangioendotheliomas and some pulmonary PEComas. Abbas Agaimy described these. pubmed.ncbi.nlm.nih.gov/33899786/
Just like Texas rarely sees snow ❄️, every once in a while you will find a primary tumor of the posterior pituitary so keep it in mind during frozen section analysis! Here is a classic example of pituicytoma showing diffuse nuclear positivity for TTF1 #pathsky #neuropath #medsky 🔬 🧠
January 19, 2025 at 8:58 PM
Just like Texas rarely sees snow ❄️, every once in a while you will find a primary tumor of the posterior pituitary so keep it in mind during frozen section analysis! Here is a classic example of pituicytoma showing diffuse nuclear positivity for TTF1 #pathsky #neuropath #medsky 🔬 🧠
Reposted by Maria Gubbiotti, MD,PhD
#PathSky 32M with extra-axial, dural-based, frontoparietal mass. Clearly malignant epithelioid cells arranged in cords and nests in a sclerotic background. Looks a lot like a sclerosing epithelioid fibrosarcoma, and it is strongly MUC4-positive. So, we’re done, right?
January 8, 2025 at 5:13 PM
#PathSky 32M with extra-axial, dural-based, frontoparietal mass. Clearly malignant epithelioid cells arranged in cords and nests in a sclerotic background. Looks a lot like a sclerosing epithelioid fibrosarcoma, and it is strongly MUC4-positive. So, we’re done, right?
Jumping into 2025 with an endolymphatic sac tumor, a VHL-associated neoplasm arising in the posterior petrous bone of the ear #pathsky #eqbsky #neuropath #entpath
January 2, 2025 at 3:12 PM
Jumping into 2025 with an endolymphatic sac tumor, a VHL-associated neoplasm arising in the posterior petrous bone of the ear #pathsky #eqbsky #neuropath #entpath
Asteroid hyalosis is an aging-associated condition of the eye where calcium and phospholipids build up giving the eye a grossly “glittery star-like” appearance (hence the name). Here is a vitreous cytology specimen before and after polarization showing the material 💫 👁️ #pathsky #medsky
December 20, 2024 at 3:24 PM
Some tumor look-a-likes on this Friday:
Chordoid meningioma and chordoma can share similar features of cords of cells in a myxoid background. Chordoma shows diffuse nuclear Brachyury expression whereas chordoid meningioma is positive for SSTR2 helping to differentiate the two 🧠 #pathsky #neuropath
Chordoid meningioma and chordoma can share similar features of cords of cells in a myxoid background. Chordoma shows diffuse nuclear Brachyury expression whereas chordoid meningioma is positive for SSTR2 helping to differentiate the two 🧠 #pathsky #neuropath
December 6, 2024 at 5:46 PM
Some tumor look-a-likes on this Friday:
Chordoid meningioma and chordoma can share similar features of cords of cells in a myxoid background. Chordoma shows diffuse nuclear Brachyury expression whereas chordoid meningioma is positive for SSTR2 helping to differentiate the two 🧠 #pathsky #neuropath
Chordoid meningioma and chordoma can share similar features of cords of cells in a myxoid background. Chordoma shows diffuse nuclear Brachyury expression whereas chordoid meningioma is positive for SSTR2 helping to differentiate the two 🧠 #pathsky #neuropath
Alternatively, if you are looking for something else consider mailchi.mp/houserabbits...
This is where we adopted our adorable bunny Teepah!
This is where we adopted our adorable bunny Teepah!
December 3, 2024 at 4:55 PM
Alternatively, if you are looking for something else consider mailchi.mp/houserabbits...
This is where we adopted our adorable bunny Teepah!
This is where we adopted our adorable bunny Teepah!
December 3, 2024 at 4:53 PM
Happy Thanksgiving! Always a time to reflect and be grateful for where we are, where we’ve been, and where we are going 😊 🦃
November 28, 2024 at 1:47 PM
Happy Thanksgiving! Always a time to reflect and be grateful for where we are, where we’ve been, and where we are going 😊 🦃
Reposted by Maria Gubbiotti, MD,PhD
Giving back to the community this holiday season 🦃
Along with the Michael Ann & Saquon Barkley Hope Foundation, acmemarkets, and Youth Mentoring Partnership, Saquon provided Thanksgiving meals to 150 families!
Along with the Michael Ann & Saquon Barkley Hope Foundation, acmemarkets, and Youth Mentoring Partnership, Saquon provided Thanksgiving meals to 150 families!
November 26, 2024 at 5:07 PM
Giving back to the community this holiday season 🦃
Along with the Michael Ann & Saquon Barkley Hope Foundation, acmemarkets, and Youth Mentoring Partnership, Saquon provided Thanksgiving meals to 150 families!
Along with the Michael Ann & Saquon Barkley Hope Foundation, acmemarkets, and Youth Mentoring Partnership, Saquon provided Thanksgiving meals to 150 families!