Kyle MacQuarrie MD PhD
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kylemacquarrie.bsky.social
Kyle MacQuarrie MD PhD
@kylemacquarrie.bsky.social
Pediatric oncologist and physician-scientist in Chicago, Asst Prof, big ol’ science nerd, 🏳️‍🌈, views my own, etc etc
She seems much less interested in the new episode of The Pitt than I am.
January 17, 2026 at 12:17 AM
Reposted by Kyle MacQuarrie MD PhD
My (now) weekly update on 2026 NIH funding.

New and competitive renewal awards.

3 new awards (compared to ~100 expected based on recent years).

No new ICs... still just NIA, NINDS, NIDCD, and NIDCR.

1/2
January 16, 2026 at 2:37 PM
Reposted by Kyle MacQuarrie MD PhD
Gold OA: the gift that keeps on giving
Rising Publication Costs Strain Researchers www.the-scientist.com/rising-publi... "Open access publishing has led to researchers paying thousands of dollars to publish their work, limiting funds for research and leaving scientists with hard choices." #Publishing #OpenAccess #Research
Rising Publication Costs Strain Researchers
Open access publishing has led to researchers paying thousands of dollars to publish their work, limiting funds for research and leaving scientists with hard choices.
www.the-scientist.com
January 13, 2026 at 5:27 PM
Reposted by Kyle MacQuarrie MD PhD
Read our full statement by AAP President Dr. Andrew Racine on today’s HHS announcement about the childhood immunization schedule: www.aap.org/en/news-room...
January 5, 2026 at 9:16 PM
Reposted by Kyle MacQuarrie MD PhD
Every single one of the vaccines “no longer universally” recommended today, is something I have seen kids in the ICU for, several of which I’ve seen die despite heroic efforts by the #PedsICU team. Freed up beds allowed us to advance other care for children, accommodating return of vanquished
January 5, 2026 at 9:36 PM
Reposted by Kyle MacQuarrie MD PhD
Scientists discovered cancer cells use interactive LINE-1 retrotransposon regions to reshape 3D genome architecture, enhancing oncogenic gene expression. This mechanism links LINE-1 activity to cancer development & highlights potential therapeutic targets. ow.ly/qVN650XS0MN
Retrotransposon drives cancer by altering 3D genome structure
See how LINE-1 retrotransposon jumping gene loci modulate cancer gene expression by altering three-dimensional genome architecture at select sites called HILLs.
ow.ly
January 5, 2026 at 4:38 PM
Reposted by Kyle MacQuarrie MD PhD
Introducing you all to @mishamehta.bsky.social who has spent tireless hours advocating for children with brain tumors, supporting researchers doing their work, and building community for other families.

We are indebted to her: www.youtube.com/watch?v=_r_7...

#PEDCan
#CanSky
#CancerSurvivors
January 4, 2026 at 6:14 PM
Note to self: in the future, remember that you store Halloween decorations in the creepy, dark space under the stairs of your 100 year old house *before* shining a flashlight in there.
January 3, 2026 at 7:23 PM
Starting off the new year with cake - a peanut butter and jelly (and chocolate) cake to be precise.

(Chocolate sponges, raspberry preserves, peanut butter Swiss buttercream, and homemade peanut brittle to be really precise.)
January 2, 2026 at 4:13 PM
The NYE/wedding anniversary/birthday combo means it’s sushi time. (Not pictured: the rest of the sushi we ordered).
January 1, 2026 at 2:36 AM
Tegan is celebrating the holidays using my favorite technique - napping so hard on the couch as to be indistinguishable from a potato.
December 24, 2025 at 7:02 PM
Reposted by Kyle MacQuarrie MD PhD
The Akhtar Lab @manneresearch.bsky.social and Northwestern University @nufeinbergmed.bsky.social is hiring a full time RESEARCH TECHNICIAN. If you want to study neonatal HSV pathogenesis please send me a message and apply for the position here:
luriechildrens.wd1.myworkdayjobs.com/externalport...
December 23, 2025 at 3:38 PM
Reposted by Kyle MacQuarrie MD PhD
I love academia, half your coworkers left yesterday evening and won't be back until Jan 6, the other half will frantically try to contact you at 8am on New Year's Day
December 19, 2025 at 11:25 PM
Reposted by Kyle MacQuarrie MD PhD
Co-sign
As a doctor I recommend the AAP childhood vaccine schedule. 😎
December 20, 2025 at 12:12 AM
Reposted by Kyle MacQuarrie MD PhD
AAP learned this week that seven grants to AAP under the U.S. Department of Health and Human Services are being terminated. The sudden withdrawal of these funds will directly impact and potentially harm infants, children, youth, and their families.
www.washingtonpost.com/health/2025/...
December 17, 2025 at 11:34 PM
Reposted by Kyle MacQuarrie MD PhD
SCOOP: American Academy of Pediatrics loses HHS funding after criticizing RFK Jr. Research included reducing sudden infant deaths and identifying autism early. Me and @Paigecunningham.Bsky.Social
www.washingtonpost.com/health/2025/...
American Academy of Pediatrics loses HHS funding after criticizing RFK Jr.
HHS cuts key AAP grants, citing concerns about “identity-based language” and insufficient focus on agency priorities. The organization said the cuts could harm child health.
www.washingtonpost.com
December 17, 2025 at 7:27 PM
Getting shown new, exciting (and pretty!) data to start my Wednesday, when I’m also feeling festive:
a man in a green elf costume is standing in a room with his mouth wide open .
ALT: a man in a green elf costume is standing in a room with his mouth wide open .
media.tenor.com
December 17, 2025 at 3:58 PM
Annual holiday lab bake-off means I had to make an identical backup cake to keep at home, in addition to the one ‘competing’.
December 12, 2025 at 3:56 AM
Reposted by Kyle MacQuarrie MD PhD
The NUCATS Mentored Career Development Program in Clinical and Translational Science (K12) is designed to train a strong workforce of investigators to drive future innovation and implement effective clinical and translational research. View the RFA — www.nucats.northwestern.edu/docs/cecd/k1...
December 11, 2025 at 5:37 PM
Reposted by Kyle MacQuarrie MD PhD
And even more data showing fewer hospitals provide pediatric care. The situation is going to continue to deteriorate until we markedly overhaul how we pay for care of children.

publications.aap.org/pediatrics/a...
Pediatric Capabilities in US Hospitals: 2003–2022
OBJECTIVE. To evaluate how availability of pediatric-capable hospitals has changed over 2 decades.METHODS. We studied US acute care hospitals from 2003 to 2022 using the Healthcare Cost and Utilizatio...
publications.aap.org
December 10, 2025 at 7:20 PM
The battles get even fiercer when your yard has about 11 inches of snowy cushioning.
December 7, 2025 at 4:20 PM
My lab and I had the pleasure recently of being involved with a piece by the Children’s Hospital Association (@hospitals4kids) on the importance of investing in pediatric medical research. You can check it out here! youtu.be/NmNIgpVddNU #MomentsMadePossible
Research is Advancing Care for Children | *Made Possible
YouTube video by Children's Hospital Association
youtu.be
December 5, 2025 at 2:37 PM
Reposted by Kyle MacQuarrie MD PhD
💬Viewpoint: Eliminating universal hepatitis B birth dose vaccination risks an estimated 8% increase in annual perinatal #HepatitisB infections in the US, increasing preventable chronic disease burden. ja.ma/3Me0zHh
December 3, 2025 at 3:45 PM
Reposted by Kyle MacQuarrie MD PhD
Pls Repost: I am putting together an edition of “Methods in Molecular Biology” focused on early development, encompassing gastrulation. I am making a list of potential authors for chapters. If interested, please contact me - An excellent opportunity for trainees to co-author with their advisors.
December 3, 2025 at 12:43 PM
Playing fetch in the deep snow really takes it out of you.
November 29, 2025 at 7:11 PM