Kasia Siudeja
@ksiudeja.bsky.social
Somatic genomes, DNA repeats, nuclear structure, stem cells and aging - Team leader @i2bcparissaclay.bsky.social - Former @bardinlab.bsky.social
Reposted by Kasia Siudeja
🧬 PhD Position: Evolutionary & Comparative Genomics 🕷️
Join us at @uni-goettingen.de for a 3-year PhD (65% TV-L E13).
We will investigate the genomic & phenotypic impact of gene duplication across 233 arthropod genomes!
More infos 👇 and s.gwdg.de/eDrAAY
#Evolution #Genomics #Bioinformatics
Join us at @uni-goettingen.de for a 3-year PhD (65% TV-L E13).
We will investigate the genomic & phenotypic impact of gene duplication across 233 arthropod genomes!
More infos 👇 and s.gwdg.de/eDrAAY
#Evolution #Genomics #Bioinformatics
Posnien - Georg-August-Universität Göttingen
Webseiten der Georg-August-Universität Göttingen
s.gwdg.de
November 18, 2025 at 7:04 AM
🧬 PhD Position: Evolutionary & Comparative Genomics 🕷️
Join us at @uni-goettingen.de for a 3-year PhD (65% TV-L E13).
We will investigate the genomic & phenotypic impact of gene duplication across 233 arthropod genomes!
More infos 👇 and s.gwdg.de/eDrAAY
#Evolution #Genomics #Bioinformatics
Join us at @uni-goettingen.de for a 3-year PhD (65% TV-L E13).
We will investigate the genomic & phenotypic impact of gene duplication across 233 arthropod genomes!
More infos 👇 and s.gwdg.de/eDrAAY
#Evolution #Genomics #Bioinformatics
Reposted by Kasia Siudeja
Deadline Nov 15 (in 2 days!). Join us in Geneva in the fantastic Dpt. of Molecular and Cellular Biology - great opportunity! mocel.unige.ch/news-events/...
Open position for assistant (tenure-track) or associate professor - Department of Molecular and Cellular Biology - UNIGE
mocel.unige.ch
November 13, 2025 at 12:14 PM
Deadline Nov 15 (in 2 days!). Join us in Geneva in the fantastic Dpt. of Molecular and Cellular Biology - great opportunity! mocel.unige.ch/news-events/...
Reposted by Kasia Siudeja
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
November 12, 2025 at 4:49 AM
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
Reposted by Kasia Siudeja
Excited to share our new preprint on BioRxiv!
A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1...
1/5
A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1...
1/5
The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons
Background. Paramecia belong to the ciliate phylum of unicellular eukaryotes characterized by nuclear dimorphism. A diploid germline micronucleus (MIC) transmits genetic information across sexual gene...
www.biorxiv.org
November 10, 2025 at 9:21 AM
Excited to share our new preprint on BioRxiv!
A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1...
1/5
A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1...
1/5
Reposted by Kasia Siudeja
Reposted by Kasia Siudeja
Glad to share our latest work showing that #drosophila epigenetic enzyme TET controls muscle development independently of its catalytic activity but prevents muscle aging in a catalytic-dependent manner!
Congratulations to Vincent and Emilie @igred.fr !
links.springernature.com/f/a/L1ogzL3H...
Congratulations to Vincent and Emilie @igred.fr !
links.springernature.com/f/a/L1ogzL3H...
TET exhibits enzymatic-independent and-dependent functions during Drosophila flight muscle development and aging - Skeletal Muscle
Background Enzymes of the Ten-Eleven Translocation family are responsible for 5-methylcytosine (5mC) oxidation and play a key role in regulating DNA demethylation during various developmental processe...
links.springernature.com
October 27, 2025 at 3:23 PM
Glad to share our latest work showing that #drosophila epigenetic enzyme TET controls muscle development independently of its catalytic activity but prevents muscle aging in a catalytic-dependent manner!
Congratulations to Vincent and Emilie @igred.fr !
links.springernature.com/f/a/L1ogzL3H...
Congratulations to Vincent and Emilie @igred.fr !
links.springernature.com/f/a/L1ogzL3H...
Reposted by Kasia Siudeja
Some impressions from the rather fabulous #EMBOmobilegenome Mobile Genome meeting in Heidelberg
Morning walk through the woods, exciting panel discussion, flash talks, lab community, drosophila friends, …
@events.embl.org
The transposon community is going very strong. see you all again in 2027!!
Morning walk through the woods, exciting panel discussion, flash talks, lab community, drosophila friends, …
@events.embl.org
The transposon community is going very strong. see you all again in 2027!!
November 7, 2025 at 7:38 AM
Some impressions from the rather fabulous #EMBOmobilegenome Mobile Genome meeting in Heidelberg
Morning walk through the woods, exciting panel discussion, flash talks, lab community, drosophila friends, …
@events.embl.org
The transposon community is going very strong. see you all again in 2027!!
Morning walk through the woods, exciting panel discussion, flash talks, lab community, drosophila friends, …
@events.embl.org
The transposon community is going very strong. see you all again in 2027!!
Reposted by Kasia Siudeja
How is epigenetic information inherited? We found that CDCA7 proteins are critical players in the inheritance of DNA methylation at CG sites in plants, and this is true both in the lab and in the wild. How does this work? 🧵👇
New paper! Work led by @p-bourguet.bsky.social and Frédéric Berger at the GMI of the @oeaw.bsky.social and @esasaki007.bsky.social identified how protein CDCA7 helps plants stably maintain epigenetic modifications across generations.
Read more: www.oeaw.ac.at/gmi/detail/n...
Read more: www.oeaw.ac.at/gmi/detail/n...
November 7, 2025 at 5:05 PM
How is epigenetic information inherited? We found that CDCA7 proteins are critical players in the inheritance of DNA methylation at CG sites in plants, and this is true both in the lab and in the wild. How does this work? 🧵👇
Reposted by Kasia Siudeja
Happy to share the results of a long-haul post-doc project, now online @science.org, aiming at understanding the rules of transgeneration epigenetic inheritance over TEs in plants and its extent and impact in nature. More below!
doi.org/10.1126/scie...
doi.org/10.1126/scie...
Transposable elements are vectors of recurrent transgenerational epigenetic inheritance
DNA methylation loss at transposable elements (TEs) can affect neighboring genes and be epigenetically inherited in plants, yet the determinants and significance of this additional system of inheritan...
doi.org
September 18, 2025 at 6:35 PM
Happy to share the results of a long-haul post-doc project, now online @science.org, aiming at understanding the rules of transgeneration epigenetic inheritance over TEs in plants and its extent and impact in nature. More below!
doi.org/10.1126/scie...
doi.org/10.1126/scie...
Reposted by Kasia Siudeja
🚨 First pre-print from my team !!
TL;DR: presence of polymorphism (sequence differences between the homologous chromosomes) can *increase* the local rate of recombination in Arabidopsis thaliana, turning cold regions of the genome hot (purple v. grey) !
TL;DR: presence of polymorphism (sequence differences between the homologous chromosomes) can *increase* the local rate of recombination in Arabidopsis thaliana, turning cold regions of the genome hot (purple v. grey) !
October 1, 2025 at 8:31 AM
🚨 First pre-print from my team !!
TL;DR: presence of polymorphism (sequence differences between the homologous chromosomes) can *increase* the local rate of recombination in Arabidopsis thaliana, turning cold regions of the genome hot (purple v. grey) !
TL;DR: presence of polymorphism (sequence differences between the homologous chromosomes) can *increase* the local rate of recombination in Arabidopsis thaliana, turning cold regions of the genome hot (purple v. grey) !
Reposted by Kasia Siudeja
🌟Im happy to share that this winter I'll be starting my lab at the Wallenberg Center for Molecular Medicine at Umeå University! Excited to join the Department of Medical and Translational Biology as a Wallenberg Fellow and looking forward to new collaborations and cool transposon research 🤩 🧬
October 26, 2025 at 4:49 PM
🌟Im happy to share that this winter I'll be starting my lab at the Wallenberg Center for Molecular Medicine at Umeå University! Excited to join the Department of Medical and Translational Biology as a Wallenberg Fellow and looking forward to new collaborations and cool transposon research 🤩 🧬
Reposted by Kasia Siudeja
I'm thrilled to announce that I’m opening my own research team in the Department of Genome Biology at I2BC @i2bcparissaclay.bsky.social ! #ATIP-Avenir
Very excited to start this new adventure! www.i2bc.paris-saclay.fr/equipe-intra...
Very excited to start this new adventure! www.i2bc.paris-saclay.fr/equipe-intra...
Equipe Courret – Institute for Integrative Biology of the Cell
www.i2bc.paris-saclay.fr
October 24, 2025 at 3:39 PM
I'm thrilled to announce that I’m opening my own research team in the Department of Genome Biology at I2BC @i2bcparissaclay.bsky.social ! #ATIP-Avenir
Very excited to start this new adventure! www.i2bc.paris-saclay.fr/equipe-intra...
Very excited to start this new adventure! www.i2bc.paris-saclay.fr/equipe-intra...
Reposted by Kasia Siudeja
To learn more about #DrosEU visit
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
DrosEU – European Drosophila Population Genomics Consortium
droseu.net
October 19, 2025 at 9:35 AM
To learn more about #DrosEU visit
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
Reposted by Kasia Siudeja
We are in Bluesky and we are happy to share our two last consortium publications: the DrosEU expanded DEST dataset and a Continent-wide study of phenotypic differentiation among European #Drosophila melanogaster populations (1/7)
October 19, 2025 at 9:35 AM
We are in Bluesky and we are happy to share our two last consortium publications: the DrosEU expanded DEST dataset and a Continent-wide study of phenotypic differentiation among European #Drosophila melanogaster populations (1/7)
Reposted by Kasia Siudeja
Hello everyone!
We decided to automate our sign-up process for the JEDI network. Please register using this link:
docs.google.com/forms/d/1IdO...
Thanks to everyone who reached out! We are looking forward to building our community with you. Share and repost!!!
#Drosophila @fly-eds.bsky.social
We decided to automate our sign-up process for the JEDI network. Please register using this link:
docs.google.com/forms/d/1IdO...
Thanks to everyone who reached out! We are looking forward to building our community with you. Share and repost!!!
#Drosophila @fly-eds.bsky.social
September 30, 2025 at 12:47 PM
Hello everyone!
We decided to automate our sign-up process for the JEDI network. Please register using this link:
docs.google.com/forms/d/1IdO...
Thanks to everyone who reached out! We are looking forward to building our community with you. Share and repost!!!
#Drosophila @fly-eds.bsky.social
We decided to automate our sign-up process for the JEDI network. Please register using this link:
docs.google.com/forms/d/1IdO...
Thanks to everyone who reached out! We are looking forward to building our community with you. Share and repost!!!
#Drosophila @fly-eds.bsky.social
Reposted by Kasia Siudeja
Hi! We are looking for a PhD to work on the cross talk between transposable elements, insects and intracellular bacteria on the bioinformatics side. The PhD would be supervised by @mariefablet.bsky.social and myself along with @nicolasparisot.bsky.social Deadline December 2025! Please share! #tesky
September 16, 2025 at 6:13 AM
Hi! We are looking for a PhD to work on the cross talk between transposable elements, insects and intracellular bacteria on the bioinformatics side. The PhD would be supervised by @mariefablet.bsky.social and myself along with @nicolasparisot.bsky.social Deadline December 2025! Please share! #tesky
Reposted by Kasia Siudeja
📢 Lancement de la campagne ATIP-Avenir 2026
@cnrsbiologie.bsky.social et @inserm.fr ouvre la campagne ATIP-Avenir 2026, destinée à soutenir des projets de recherche innovants portés par de jeunes chercheuses et chercheurs.
📅 Toutes les informations : buff.ly/5DH6mpd
@cnrsbiologie.bsky.social et @inserm.fr ouvre la campagne ATIP-Avenir 2026, destinée à soutenir des projets de recherche innovants portés par de jeunes chercheuses et chercheurs.
📅 Toutes les informations : buff.ly/5DH6mpd
September 15, 2025 at 8:45 AM
📢 Lancement de la campagne ATIP-Avenir 2026
@cnrsbiologie.bsky.social et @inserm.fr ouvre la campagne ATIP-Avenir 2026, destinée à soutenir des projets de recherche innovants portés par de jeunes chercheuses et chercheurs.
📅 Toutes les informations : buff.ly/5DH6mpd
@cnrsbiologie.bsky.social et @inserm.fr ouvre la campagne ATIP-Avenir 2026, destinée à soutenir des projets de recherche innovants portés par de jeunes chercheuses et chercheurs.
📅 Toutes les informations : buff.ly/5DH6mpd
🤯
How is this possible?
This ant can lay eggs of two different species, birthed by the same mother
This ant can lay eggs of two different species, birthed by the same mother
September 4, 2025 at 7:05 AM
🤯
Reposted by Kasia Siudeja
@fly-jedi.bsky.social please note that @droseu.bsky.social is now on Bluesky
September 2, 2025 at 10:00 AM
@fly-jedi.bsky.social please note that @droseu.bsky.social is now on Bluesky
Reposted by Kasia Siudeja
Extremely excited to share that I’m joining Columbia University @columbiauniversity.bsky.social as an Assistant Professor!
We will explore how the mobile genome works—how transposons shape us, our DNA and how they can be harnessed to build useful technologies. #NewPI #RNAsky #TEsky
thawanilab.org
We will explore how the mobile genome works—how transposons shape us, our DNA and how they can be harnessed to build useful technologies. #NewPI #RNAsky #TEsky
thawanilab.org
The Thawani Lab at Columbia University
The Thawani Lab at Columbia University describing their research on mobile genome, cryo-electron microscopy and genome engineering
thawanilab.org
August 19, 2025 at 5:00 PM
Extremely excited to share that I’m joining Columbia University @columbiauniversity.bsky.social as an Assistant Professor!
We will explore how the mobile genome works—how transposons shape us, our DNA and how they can be harnessed to build useful technologies. #NewPI #RNAsky #TEsky
thawanilab.org
We will explore how the mobile genome works—how transposons shape us, our DNA and how they can be harnessed to build useful technologies. #NewPI #RNAsky #TEsky
thawanilab.org
Reposted by Kasia Siudeja
Join junior group leaders using #Drosophila to understand development, #CellBiology, #evolution and more at the EMBO Workshop on Molecular and Developmental Biology of Drosophila, 21–27 June 2026 in Kolymbari, Greece.
Deadline: 3 November
meetings.embo.org/event/26-dro...
#EMBOevents #GeneSky 🧪
Deadline: 3 November
meetings.embo.org/event/26-dro...
#EMBOevents #GeneSky 🧪
Molecular and Developmental Biology of Drosophila
The principal theme of the EMBO Workshop is the Molecular and Developmental Biology of Drosophila. Supported by EMBO over four decades, this will be the 24th biennial “Crete meeting”. With the a…
meetings.embo.org
August 13, 2025 at 6:49 AM
Join junior group leaders using #Drosophila to understand development, #CellBiology, #evolution and more at the EMBO Workshop on Molecular and Developmental Biology of Drosophila, 21–27 June 2026 in Kolymbari, Greece.
Deadline: 3 November
meetings.embo.org/event/26-dro...
#EMBOevents #GeneSky 🧪
Deadline: 3 November
meetings.embo.org/event/26-dro...
#EMBOevents #GeneSky 🧪
Reposted by Kasia Siudeja
This is terrible news.
Clearly, a solution MUST be found!
Flybase is ESSENTIAL!!
Clearly, a solution MUST be found!
Flybase is ESSENTIAL!!
An absolutely awful turn of events. I am heartbroken over the firing of the Flybase staff. Thanks to @claudia-lopez.bsky.social for covering this important story.
FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research.
By @claudia-lopez.bsky.social
www.thetransmitter.org/community/ha...
By @claudia-lopez.bsky.social
www.thetransmitter.org/community/ha...
August 14, 2025 at 7:27 AM
This is terrible news.
Clearly, a solution MUST be found!
Flybase is ESSENTIAL!!
Clearly, a solution MUST be found!
Flybase is ESSENTIAL!!
Reposted by Kasia Siudeja
Our new paper is out in @currentbiology.bsky.social! Using 3D reconstructions and volume measurements in Drosophila wing primordia, we show that growth can be uncoupled from cell proliferation and uncover a new time window for growth arrest.
With @leopoldlab.bsky.social
www.cell.com/current-biol...
With @leopoldlab.bsky.social
www.cell.com/current-biol...
A switch to non-proliferative growth sustains Drosophila wing development during the early pupal stage
Using precise tissue volume quantification, El Marzkioui, Gaugué, et al. show that
wing primordia continue to grow during the early pupal stage, a phase of increased
cell volume driven by insulin/IGF ...
www.cell.com
August 10, 2025 at 3:01 PM
Our new paper is out in @currentbiology.bsky.social! Using 3D reconstructions and volume measurements in Drosophila wing primordia, we show that growth can be uncoupled from cell proliferation and uncover a new time window for growth arrest.
With @leopoldlab.bsky.social
www.cell.com/current-biol...
With @leopoldlab.bsky.social
www.cell.com/current-biol...
Reposted by Kasia Siudeja
DNA methylation at #retrotransposons protects the #germline by preventing NRF1-mediated #activation.
-> www.embopress.org/doi/full/10....
-> www.embopress.org/doi/full/10....
August 7, 2025 at 10:54 AM
DNA methylation at #retrotransposons protects the #germline by preventing NRF1-mediated #activation.
-> www.embopress.org/doi/full/10....
-> www.embopress.org/doi/full/10....
Reposted by Kasia Siudeja
Now online! Composite transposons with bivalent histone marks function as RNA-dependent enhancers in cell fate regulation
Composite transposons with bivalent histone marks function as RNA-dependent enhancers in cell fate regulation
This study reveals that composite transposons with bivalent histone marks can serve as RNA-dependent enhancers, controlling key developmental and aging-related gene programs.
dlvr.it
August 6, 2025 at 2:59 PM
Now online! Composite transposons with bivalent histone marks function as RNA-dependent enhancers in cell fate regulation