Kateryna Shkarina
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kshkarina.bsky.social
Kateryna Shkarina
@kshkarina.bsky.social
PostDoc in Eicke Latz lab @iii Bonn (previously - PhD @brozlab.bsky.social) working on inflammasomes and cell death and their role in inflammation and tissue repair. Passionate about all things #microscopy, #optogenetics and #cycling 🔬🚴🏼‍♀️.
Even rare #CellDeath events matter: a new study from Lamkanfi lab shows that small fraction of pyroptotic monocytes accounts for the most of IL-1β production following LPS stimulation, challenging the previously proposed models of IL-1β secretion from the living cells:
Single-cell analysis reveals cell death as driver of NLRP3-mediated secretion of IL-1β in human monocytes - Nature Immunology
Lamkanfi, Shirasaki, Izawa and colleagues show that IL-1β release in human monocytes stimulated with lipopolysaccharide or carrying NLRP3 activatory mutations is mostly restricted to cells undergoing ...
www.nature.com
November 14, 2025 at 10:55 AM
Reposted by Kateryna Shkarina
𝗖𝗮𝗻 𝗰𝗲𝗹𝗹𝘀 𝗲𝘃𝗲𝗿 𝘁𝗿𝘂𝗹𝘆 𝗿𝗲𝗰𝗼𝘃𝗲𝗿 𝗳𝗿𝗼𝗺 𝗗𝗡𝗔 𝗱𝗮𝗺𝗮𝗴𝗲?Excited to share our new study “Repair of DNA double-strand breaks leaves heritable impairment to genome function”, revealing DNA repair’s hidden cost, out now @science.org tinyurl.com/5n6zw3ye. Led by @sbantele.bsky.social and Jiri Lukas.🧵👇1/n
Repair of DNA double-strand breaks leaves heritable impairment to genome function
Upon DNA breakage, a genomic locus undergoes alterations in three-dimensional chromatin architecture to facilitate signaling and repair. Although cells possess mechanisms to repair damaged DNA, it is ...
tinyurl.com
November 6, 2025 at 11:05 PM
Reposted by Kateryna Shkarina
Jo in our team - we are looking for a PhD student, postdoc or lab manager!

More information and links to job portal for application submission:

lnkd.in/dcU2Vg7W

lnkd.in/dgVKTARV

Please share widely 🙏🏼
@yefis-immunology.bsky.social @syis-ecr.bsky.social
Postdoc or PhD student position in molecular dissection of cellular crosstalk in the intestinal mucosa
lnkd.in
November 11, 2025 at 6:20 AM
Reposted by Kateryna Shkarina
🌍Open call: Junior Group Leader positions!

Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.

Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
November 10, 2025 at 1:26 PM
This week´s issue of Biomednews on everything related to #CellDeath: biomed.news/bims-cediti/...
Highlight of this week: Structural insights into the atypical filament assembly of pyrin domain-containing IFI16, and its difference from inflammasome-forming PYDs:
Structural insights into the atypical filament assembly of pyrin domain-containing IFI16 | The EMBO Journal
imageimageThe pyrin domain (PYD)-containing interferon-inducible protein 16 (IFI16) has various inflammasome-independent functions, while it has also been suggested as a DNA sensor for inflammasome fo...
www.embopress.org
November 9, 2025 at 9:40 AM
A glimpse of autumn macro world instead of the usual micro
November 5, 2025 at 5:43 PM
The most colourful season #cycling #PostdocLife
November 2, 2025 at 6:27 PM
Today I accidentally discovered the ySG podcast "Climbing the Immunological Ladder".
Highlight: an absolutely incredible episode with Adrian Liston @labliston.bsky.social: "Caring about people and caring about their growth ends up being the most impactful thing you can do in science"
Interview with Adrian Liston
open.spotify.com
October 29, 2025 at 3:30 PM
Reposted by Kateryna Shkarina
We are hiring! 🧫 🧬 🚀

Three PhD studentships with start dates in 2026 available in the Molecular Mucosal Immunology lab at the Botnar Institute of Immune Engineering, Basel, Switzerland.

See here for details (Deadline: 7th November 2025):

join.com/companies/im...
Botnar Institute of Immune Engineering - BIIE (Zürich): Doctoral studentships, Molecular Mucosal Immunology Group
Botnar Institute of Immune Engineering - BIIE has a job opening for Doctoral studentships, Molecular Mucosal Immunology Group in Zürich (published: 29.10.2025). Apply now or check the other available...
join.com
October 29, 2025 at 12:51 PM
Is SARM1 another cytoplasmic DNA sensor? 👇
SARM1 senses dsDNA to promote NAD+ degradation and cell death @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
October 28, 2025 at 7:52 AM
Reposted by Kateryna Shkarina
#Openpositions #ImmunoSky #MedSky #wearehiring
Are you a postdoctoral researcher with an excellent track record in immunology research and/or a related field? Come and work with us in Finland!
👉Read more: bit.ly/43C68Fd
October 27, 2025 at 7:25 AM
Sounds like a genuinely horrible idea: why the first gets "lesser" score than the last, how does it account for the author positioning differences across disciplines, how is it going to account for the co-first/co-last authorships and why to devalue collaborative research
Google Scholar has introduced a 'Sh-index' metric that scores papers higher if you are first or last author. Apart from the fact metrics are generally bad, this one explicitly punishes PIs who often collaborate, publishing with 2 or 3 equal PIs at the end of the list.
www.nature.com/articles/d41...
Google Scholar tool gives extra credit to first and last authors
Researchers welcome the initiative, but say it doesn’t go far enough to capture the nuance of researcher productivity and impact.
www.nature.com
October 26, 2025 at 1:25 PM
Over the past few months, I started to curate a weekly issue of the weekly issue of the BioMed News @biomednews.bsky.social on #CellDeath.
Highlight of this week: further mechanistic clarification of how viral infections can drive endogenous Z-NA production: www.nature.com/articles/s41...
bims-cediti 2025-10-19 papers
biomed.news
October 26, 2025 at 1:11 PM
A really interesting new study from Ivan Poon and @someblondesci.bsky.social on the "footprint of death" - apoptotic cell remnants generated following apoptotic cell retraction.
The formation of the ‘footprint of death’ as a mechanism for generating large substrate-bound extracellular vesicles that mark the site of cell death - Nature Communications
Apoptotic cells often release extracellular vesicles that aid in their clearance and provide molecular information to cellular neighbours. Here, the authors show that some adherent apoptotic cells als...
www.nature.com
October 26, 2025 at 1:00 PM
Reposted by Kateryna Shkarina
Have you considered submitting a paper to @jhumimmunity.org ?

To know more about us, please read our inaugural editorial: rupress.org/jhi/article/...
Human immunity | Journal of Human Immunity | Rockefeller University Press
Human immunity is often insufficient against infectious agents and sometimes over-reactive to innocuous components of the environment or the human body. Ge
rupress.org
October 26, 2025 at 8:09 AM
Considering all the recent cuts in science funding across the globe, a very necessary Nobel Prize:
October 24, 2025 at 11:41 AM
Reposted by Kateryna Shkarina
🔔 Chech out this new cool story on non-canonical inflammasome signaling in NK cells by @protinnimmunity.bsky.social
Non-canonical inflammasome drives intrinsic anti-microbial responses in human Natural Killer (NK) cells. https://www.biorxiv.org/content/10.1101/2025.10.20.682800v1
October 21, 2025 at 7:38 PM
Reposted by Kateryna Shkarina
We hiring! Please share this post with your talented ECRs

We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome

Based at @lmcb-ucl.bsky.social at University College London

Apply here:
www.jobs.ac.uk/job/DPD418/r...
October 21, 2025 at 3:57 PM
Reposted by Kateryna Shkarina
#InflammaZoom free Webinar is back on Monday October 20th! With James Murphy (WEHI, Melbourne, Australia) @pseudokinase.bsky.social and Jonathan Maelfait (VIB-UGent, Ghent, Belgium)

Register now: bit.ly/4iXGqjw
October 17, 2025 at 6:29 AM
Reposted by Kateryna Shkarina
Starting your own lab is exciting—but challenging.
Join our GBM Young Investigator leadership workshop in Regensburg, April 13–16th, 2026.
Professional coaching, peer networking & practical tips for new PIs.
Apply by Nov 30, 2025.
👉 gbm-online.de/de/young-inv...
Pls repost!
October 15, 2025 at 1:57 PM
Reposted by Kateryna Shkarina
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 15, 2025 at 12:22 PM
Reposted by Kateryna Shkarina
“I was never working alone—there were people all over the world who shared similar ideas,” he said. “I see this award as one that represents all of those people who have contributed to this research alongside me.”

Prices go to individual people, but Sakaguchi shows how to acknowledge the field.
“Anyone who does not have an autoimmune disease, that’s because of these regulatory T cells,” says Markus Feuerer, an immunologist at the Leibniz Institute for Immunotherapy.

www.science.org/content/arti...
Medicine Nobel for researchers who identified immune system’s security guards
Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi discovered regulatory T cells that prevent autoimmune disease
www.science.org
October 6, 2025 at 7:54 PM
Reposted by Kateryna Shkarina
EXCITING NEWS!! We're searching for a new professor colleague at the Biozentrum🇨🇭. Ideal candidates are exploring novel biological questions with structure, biophysics, or high-resolution imaging. 🧪 🧶🧬 🔬

The call closes Nov 3. Please get in touch if you would like more information. Come join us! 👩‍🔬🤓
September 30, 2025 at 9:52 AM
Reposted by Kateryna Shkarina
Full room at the start of the 2nd Immunobiology symposium on pattern recognition receptors!
Looking forward to the great programme that we lined up for you together with @brozlab.bsky.social @martinon.bsky.social

#ImmunoSky
October 1, 2025 at 7:51 AM