Eric Chevet
@ericchevet.bsky.social
ER_literature, endoplasmic reticulum, proteostasis, secretory pathway, cancer research and more
PI @inserm
https://oss-clcc.univ-rennes.fr/
PI @inserm
https://oss-clcc.univ-rennes.fr/
Reposted by Eric Chevet
Multilingualism protects against accelerated aging in cross-sectional and longitudinal analyses of 27 European countries
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Multilingualism protects against accelerated aging in cross-sectional and longitudinal analyses of 27 European countries - Nature Aging
In cross-sectional and longitudinal analyses of 86,149 participants across 27 European countries, Amoruso, Hernandez and colleagues identify multilingualism as a protective factor against accelerated ...
www.nature.com
November 11, 2025 at 10:35 AM
Multilingualism protects against accelerated aging in cross-sectional and longitudinal analyses of 27 European countries
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Reposted by Eric Chevet
Reposted by Eric Chevet
« les autres réductions notables concernent le travail, l’emploi et les ministères sociaux pour 800 millions d’euros, et la recherche et l’enseignement supérieur pour 250 millions d’euros… » 😑
Sébastien Lecornu veut annuler des crédits de 4,2 milliards d’euros pour tenir le déficit 2025
Le projet de loi de fin de gestion a été validé lundi 10 novembre par le conseil des ministres. Il prévoit de nouveaux ajustements budgétaires, afin d’éviter un dérapage des comptes de l’année qui s’a...
www.lemonde.fr
November 10, 2025 at 6:39 PM
« les autres réductions notables concernent le travail, l’emploi et les ministères sociaux pour 800 millions d’euros, et la recherche et l’enseignement supérieur pour 250 millions d’euros… » 😑
Reposted by Eric Chevet
Check out our @ascbiology.bsky.social #CellBio2025 Minisymposium on ER Homeostasis. With THIS speaker lineup, this event will be as dynamic, transformative and productive as the ER itself!
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
November 9, 2025 at 6:04 PM
Check out our @ascbiology.bsky.social #CellBio2025 Minisymposium on ER Homeostasis. With THIS speaker lineup, this event will be as dynamic, transformative and productive as the ER itself!
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
Reposted by Eric Chevet
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming! Super interesting papers this issue (including our last study😂🤩😛) Enjoy! 🙏 @biomednews.bsky.social biomed.news/bims-meract/...
a man says i need you to pick one
ALT: a man says i need you to pick one
media.tenor.com
November 9, 2025 at 8:23 AM
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming! Super interesting papers this issue (including our last study😂🤩😛) Enjoy! 🙏 @biomednews.bsky.social biomed.news/bims-meract/...
DDX3X acts as a selective dual switch regulator of mRNA translation in acute ER stress
DDX3X acts as a selective dual switch regulator of mRNA translation in acute ER stress
Shawky et al. show that DDX3X selectively promotes or represses mRNA translation in a stress-dependent manner. This bidirectional regulation involves position-specific binding to the mRNA 5′ UTR and early coding region, reflecting distinct mechanisms, including initiation control during 48S scanning and translational repression associated with ac4C post-transcriptional modification.
dlvr.it
November 9, 2025 at 3:31 PM
Reposted by Eric Chevet
Mais.
Les députés rejettent la vaccination obligatoire contre la grippe pour les résidents d’Ehpad et certains soignants
L’alliance RN-UDR et une large majorité des députés LFI ont voté contre
➡️ https://l.leparisien.fr/0J2w
L’alliance RN-UDR et une large majorité des députés LFI ont voté contre
➡️ https://l.leparisien.fr/0J2w
November 9, 2025 at 8:57 AM
Mais.
Reposted by Eric Chevet
This week´s issue of Biomednews on everything related to #CellDeath: biomed.news/bims-cediti/...
Highlight of this week: Structural insights into the atypical filament assembly of pyrin domain-containing IFI16, and its difference from inflammasome-forming PYDs:
Highlight of this week: Structural insights into the atypical filament assembly of pyrin domain-containing IFI16, and its difference from inflammasome-forming PYDs:
Structural insights into the atypical filament assembly of pyrin domain-containing IFI16 | The EMBO Journal
imageimageThe pyrin domain (PYD)-containing interferon-inducible protein 16 (IFI16) has various
inflammasome-independent functions, while it has also been suggested as a DNA sensor
for inflammasome fo...
www.embopress.org
November 9, 2025 at 9:40 AM
This week´s issue of Biomednews on everything related to #CellDeath: biomed.news/bims-cediti/...
Highlight of this week: Structural insights into the atypical filament assembly of pyrin domain-containing IFI16, and its difference from inflammasome-forming PYDs:
Highlight of this week: Structural insights into the atypical filament assembly of pyrin domain-containing IFI16, and its difference from inflammasome-forming PYDs:
This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: Secretome translation shaped by lysosomes and lunapark-marked ER junctions www.nature.com/articles/s41...
Highlight: Secretome translation shaped by lysosomes and lunapark-marked ER junctions www.nature.com/articles/s41...
bims-proteo 2025-11-09 papers
biomed.news
November 9, 2025 at 6:37 AM
This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: Secretome translation shaped by lysosomes and lunapark-marked ER junctions www.nature.com/articles/s41...
Highlight: Secretome translation shaped by lysosomes and lunapark-marked ER junctions www.nature.com/articles/s41...
Reposted by Eric Chevet
Good Sunday, all. The weekly curated issue of papers in #cancermetabolism and #mitochondrialbiology is out, a concentrate of groundbreaking discoveries:
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"There are years that ask questions and years that answer."-Zora Neale Hurston
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"There are years that ask questions and years that answer."-Zora Neale Hurston
November 9, 2025 at 6:28 AM
Good Sunday, all. The weekly curated issue of papers in #cancermetabolism and #mitochondrialbiology is out, a concentrate of groundbreaking discoveries:
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"There are years that ask questions and years that answer."-Zora Neale Hurston
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"There are years that ask questions and years that answer."-Zora Neale Hurston
Reposted by Eric Chevet
🙏
OpenAI pirated large numbers of books and used them to train models.
OpenAI then deleted the dataset with the pirated books, and employees sent each other messages about doing so.
A lawsuit could now force the company to pay $150,000 per book, adding up to billions in damages.
OpenAI then deleted the dataset with the pirated books, and employees sent each other messages about doing so.
A lawsuit could now force the company to pay $150,000 per book, adding up to billions in damages.
November 4, 2025 at 7:28 PM
🙏
Reposted by Eric Chevet
Induced proximity-based therapeutic modalities
nature.com/articles/s41...
rdcu.be/eOfBH
This new Review by @dannomura.bsky.social et al. discusses the rapidly expanding landscape of therapeutic approaches based on inducing proximity between proteins, including targeted protein degraders and more
nature.com/articles/s41...
rdcu.be/eOfBH
This new Review by @dannomura.bsky.social et al. discusses the rapidly expanding landscape of therapeutic approaches based on inducing proximity between proteins, including targeted protein degraders and more
Induced proximity-based therapeutic modalities - Nature Reviews Drug Discovery
Induced proximity modalities encompass monovalent and bifunctional agents, such as molecular glues and proteolysis-targeting chimeras, that induce an interaction between biomolecules to functionally m...
nature.com
November 4, 2025 at 4:12 PM
Induced proximity-based therapeutic modalities
nature.com/articles/s41...
rdcu.be/eOfBH
This new Review by @dannomura.bsky.social et al. discusses the rapidly expanding landscape of therapeutic approaches based on inducing proximity between proteins, including targeted protein degraders and more
nature.com/articles/s41...
rdcu.be/eOfBH
This new Review by @dannomura.bsky.social et al. discusses the rapidly expanding landscape of therapeutic approaches based on inducing proximity between proteins, including targeted protein degraders and more
Reposted by Eric Chevet
Sinon @phbaptiste.bsky.social comment vous envisagez votre réaction à un institut public qui se fout ouvertement de votre gueule quand vous ne suivez pas la recommandation du @hceres.bsky.social et vous prend à témoin ?
Vu que votre responsabilité est engagée.
Qu'en pense @ofis-france.bsky.social ?🔽
Vu que votre responsabilité est engagée.
Qu'en pense @ofis-france.bsky.social ?🔽
Donc l'IHU de Marseille MENT sur son site web officiel en prêtant au @hceres.bsky.social les propos exactement inverses de ce que le HCERES écrit, puisque le HCERES recommande de VIRER presque toute l'équipe de direction dont le dirlo lui-même.
Et l'IHU modifie en douce le nom de domaine.
RT SVP🔽
Et l'IHU modifie en douce le nom de domaine.
RT SVP🔽
L'IHU Mi, cet univers parallèle ! A gauche, ce que l'on trouve sur la page d'accueil de son site Internet, à droite, un extrait du rapport HCERES
archive.ph/ZkB90
archive.wikiwix.com/cache/index2...
archive.ph/ZkB90
archive.wikiwix.com/cache/index2...
November 4, 2025 at 6:20 PM
Sinon @phbaptiste.bsky.social comment vous envisagez votre réaction à un institut public qui se fout ouvertement de votre gueule quand vous ne suivez pas la recommandation du @hceres.bsky.social et vous prend à témoin ?
Vu que votre responsabilité est engagée.
Qu'en pense @ofis-france.bsky.social ?🔽
Vu que votre responsabilité est engagée.
Qu'en pense @ofis-france.bsky.social ?🔽
Reposted by Eric Chevet
Language models cannot reliably distinguish belief from knowledge and fact #AI
Failure to make such distinctions can mislead diagnoses, distort judicial judgments and amplify misinformation.
www.nature.com/articles/s42...
Failure to make such distinctions can mislead diagnoses, distort judicial judgments and amplify misinformation.
www.nature.com/articles/s42...
Language models cannot reliably distinguish belief from knowledge and fact - Nature Machine Intelligence
Suzgun et al. find that current large language models cannot reliably distinguish between belief, knowledge and fact, raising concerns for their use in healthcare, law and journalism, where such disti...
www.nature.com
November 4, 2025 at 10:13 AM
Language models cannot reliably distinguish belief from knowledge and fact #AI
Failure to make such distinctions can mislead diagnoses, distort judicial judgments and amplify misinformation.
www.nature.com/articles/s42...
Failure to make such distinctions can mislead diagnoses, distort judicial judgments and amplify misinformation.
www.nature.com/articles/s42...
Reposted by Eric Chevet
#MembraneTraffickers! Our next online seminar is this Thursday, Nov 6 at 5 PM CEST!
We’ll hear from @agatawitkowska.bsky.social on mechanical control of neurotransmission and @abdourachidthiam.bsky.social on lipid storage mechanisms in health and disease.
Spread the word and join the discussion!
We’ll hear from @agatawitkowska.bsky.social on mechanical control of neurotransmission and @abdourachidthiam.bsky.social on lipid storage mechanisms in health and disease.
Spread the word and join the discussion!
November 3, 2025 at 7:33 PM
#MembraneTraffickers! Our next online seminar is this Thursday, Nov 6 at 5 PM CEST!
We’ll hear from @agatawitkowska.bsky.social on mechanical control of neurotransmission and @abdourachidthiam.bsky.social on lipid storage mechanisms in health and disease.
Spread the word and join the discussion!
We’ll hear from @agatawitkowska.bsky.social on mechanical control of neurotransmission and @abdourachidthiam.bsky.social on lipid storage mechanisms in health and disease.
Spread the word and join the discussion!
Reposted by Eric Chevet
It’s the Nigel Farage chameleon show – flashy, ever-changing pledges, but only one real policy: xenophobia | Polly Toynbee
It’s the Nigel Farage chameleon show – flashy, ever-changing pledges, but only one real policy: xenophobia | Polly Toynbee
The Reform leader’s speech was full of contradictions and damaging cuts. But if he makes it to No 10, Labour will be to blame, says Guardian columnist Polly Toynbee
www.theguardian.com
November 3, 2025 at 7:13 PM
It’s the Nigel Farage chameleon show – flashy, ever-changing pledges, but only one real policy: xenophobia | Polly Toynbee
Reposted by Eric Chevet
Une gestion purement comptable; que le ministère des finances considère encore et toujours que l' #ESR soit un coût alors que c'est un investissement
Quels sont d'après-vous les principaux problèmes rencontrés par les enseignants-chercheurs et les chercheurs en France aujourd'hui ?
November 3, 2025 at 11:37 AM
Une gestion purement comptable; que le ministère des finances considère encore et toujours que l' #ESR soit un coût alors que c'est un investissement
Reposted by Eric Chevet
L'avenir de la science, ce sont les fraudeurs du passé qui n'ont pas eu à répondre de leurs actes....
November 3, 2025 at 6:45 PM
L'avenir de la science, ce sont les fraudeurs du passé qui n'ont pas eu à répondre de leurs actes....
Reposted by Eric Chevet
Big New! @elife.bsky.social @genetics-gsa.bsky.social #G3journal are joining editorial forces with @reviewcommons.org - bringing not just field-specific expertise to the process but also making #PreprintPeerReview a truly collaborative effort!🎉👏
Read more to find out👇
www.embo.org/features/pub...
Read more to find out👇
www.embo.org/features/pub...
Publishers join the Review Commons peer review process – Features – EMBO
Editors from eLife, Genetics, G3 and Journal of Cell Biology will contribute to the EMBO preprint peer review platform
www.embo.org
November 3, 2025 at 9:33 AM
Big New! @elife.bsky.social @genetics-gsa.bsky.social #G3journal are joining editorial forces with @reviewcommons.org - bringing not just field-specific expertise to the process but also making #PreprintPeerReview a truly collaborative effort!🎉👏
Read more to find out👇
www.embo.org/features/pub...
Read more to find out👇
www.embo.org/features/pub...
Reposted by Eric Chevet
When ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants.
Age and gender distortion in online media and large language models - Nature
Stereotypes of age-related gender bias are socially distorted, as evidenced by the age gap in the representations of women and men across various media and algorithms, despite no systematic age differ...
www.nature.com
November 2, 2025 at 9:47 PM
When ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants.
Reposted by Eric Chevet
AI amplify gender biases, simply reflecting biases in training data.
#whatcouldpossiblygowrong
#womeninscience
#whatcouldpossiblygowrong
#womeninscience
This week's @nature.com cover highlights a report of A.I.- mediated distortion
When #ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants nature.com/articles/s41...
When #ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants nature.com/articles/s41...
November 2, 2025 at 7:17 PM
AI amplify gender biases, simply reflecting biases in training data.
#whatcouldpossiblygowrong
#womeninscience
#whatcouldpossiblygowrong
#womeninscience
Reposted by Eric Chevet
Elon Musk FRS is a piece of sh--. Excuse my language, but after the attack in Huntingdon and the firework attack on a refugee quarters in Drogheda, nothing else occurs to me right now. @royalsociety.org
Elon Musk, "These lovely small towns in England, Scotland and Ireland, they've been living their lives quietly. They're like hobbits"
"And so one day, 1,000 people show up in your village of 500 and start raping the kids"
"This has now happened, God knows how many times in Britain"
"And so one day, 1,000 people show up in your village of 500 and start raping the kids"
"This has now happened, God knows how many times in Britain"
November 2, 2025 at 9:11 PM
Elon Musk FRS is a piece of sh--. Excuse my language, but after the attack in Huntingdon and the firework attack on a refugee quarters in Drogheda, nothing else occurs to me right now. @royalsociety.org
Reposted by Eric Chevet
Good Sunday, mitolovers. Here is a wonderful selection of papers in #cancermetabolism and #mitochondrialbiology:
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"Coming back to where you started is not the same as never leaving."-Terry Pratchett
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"Coming back to where you started is not the same as never leaving."-Terry Pratchett
November 2, 2025 at 5:49 AM
Good Sunday, mitolovers. Here is a wonderful selection of papers in #cancermetabolism and #mitochondrialbiology:
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"Coming back to where you started is not the same as never leaving."-Terry Pratchett
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"Coming back to where you started is not the same as never leaving."-Terry Pratchett