Killian Hurley
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killianhurley.bsky.social
Killian Hurley
@killianhurley.bsky.social
Physician-scientist and pulmonary fibrosis doc developing new treatments for #IPF.🧪 🫁 European Research Council grant awardee.

#CureIPF #iPSC #Telomeres #CleanAir #SciSky #MedSky

Interested in #running, #sailing & #nature.

LivingLungLab.com
Reposted by Killian Hurley
This is a problem. Internet searches have been a cause for concern (and occasionally help) for a while now. A lot of background knowledge is needed to make sense of the suggestions thrown up by searches, but the AI summaries simply aren’t reliable.
www.theguardian.com/technology/2...
‘Dangerous and alarming’: Google removes some of its AI summaries after users’ health put at risk
Guardian investigation finds AI Overviews provided inaccurate and false information when queried over blood tests
www.theguardian.com
January 11, 2026 at 10:00 AM
Interesting article about how car design and diesel affects how much air pollution we breathe.

It’s time to improve air quality on our streets for our own health and our children’s future health.

#cleanair

@rcsi.bsky.social
@irishthoracicsoc.bsky.social

www.theguardian.com/environment/...
Exhaust pipe position affects how much air pollution we breathe, research finds
Cars that emit fumes closer to pavement result in pedestrians experiencing 40% more pollution
www.theguardian.com
January 10, 2026 at 11:21 AM
Reposted by Killian Hurley
New: Phosphodiesterase 4B inhibitor Nerandomilast first of its kind to be approved for progressive pulmonary fibrosis

www.medscape.com/viewarticle/...
FDA Approves Nerandomilast for PPF
New indication follows recent approval for idiopathic pulmonary fibrosis.
www.medscape.com
December 24, 2025 at 8:13 PM
Reposted by Killian Hurley
Last summer I announced that, after 13 years, I will step down as Chief of #YalePCCSM in June 2026. And now the search for the #NextChief is on!!!
Read more about our section at medicine.yale.edu/news-article...
Kaminski to Step Down as Yale-PCCSM Section Chief in June 2026
When Naftali Kaminski, MD, was recruited to Yale in 2013 as section chief of Pulmonary, Critical Care and Sleep Medicine (Yale-PCCSM) he planned to lead it for
medicine.yale.edu
December 20, 2025 at 7:17 PM
People with #rheumatoid arthiris and #scleroderma who have lung fibrosis can safely and effectively monitor their breathing and oxygen levels at home.

Read our paper in @bmc.springernature.com describing how patients face and overcome challenges.

@irishthoracicsoc.bsky.social

rdcu.be/eQV9e
Remote monitoring of spirometry and oximetry in patients with connective tissue disease related interstitial lung disease: a prospective observational cohort study
rdcu.be
November 20, 2025 at 12:30 PM
Reposted by Killian Hurley
I am calling upon the people of Ireland to immediately begin construction of a thread on this site about how you or someone you know was roasted for a fashion choice. We need it.

All roasts must have come from Irish people *only*. Please respect this important rule, it makes a difference.

Tanks
November 12, 2025 at 5:45 AM
Reposted by Killian Hurley
EMBL scientists have created a more sensitive single-cell sequencing tool for genomic variants and RNA in the same single cell.

Known as SDR-seq, the tool has unprecedented scale, precision, and speed to characterise variants and link them to functions and disease.

www.embl.org/news/science...
New tool offers single-cell study of specific genetic variants | EMBL
Scientists developed a more sensitive single-cell sequencing tool linking genomic variants & RNA in the same cell uncover links to disease.
www.embl.org
October 10, 2025 at 10:23 AM
Reposted by Killian Hurley
Delighted that Ziqi Dong's PhD paper is out for all to read! Hypoxia is fundamental to normal development, and fascinating! Thanks to all of our co-authors including @jamesnathanlab.bsky.social @jellevda.bsky.social authors.elsevier.com/sd/article/S...
October 11, 2025 at 8:22 AM
Fascinating work on the regulation of telomere length - molecular clocks we all have in our cells controlling aging and disease.

Emerging evidence of their role pulmonary fibrosis.

#CureIPF
#Telomeres

@elife.bsky.social
@rcsi.bsky.social
@kaminskimed.bsky.social
Your chromosomes have protective ends called telomeres. As they shorten, your cells age. This study reveals how a protein, TRF2, directly regulates telomerase activity to keep telomeres in check.
Keeping telomeres at the right length
The key telomere protein TRF2 helps regulate telomere length by interacting with the telomerase gene TERT in a length-dependent manner.
buff.ly
October 4, 2025 at 4:33 PM
Great work by Dr Aoife Carolan from our group at @rcsi.bsky.social
RCSI showing data from our familial pulmonary fibrosis clinic.

- 1 in 5 patients have a family memeber with lung fibrosis.

- 1 in 5 of these patients have a single suspected gene.

#CureIPF

@europeanrespsoc.bsky.social
September 29, 2025 at 6:07 AM
Gene variants such as MUC5B can increase the risk for lung fibrosis/IPF.

We found a strong correlation with high frequency of the variant per county and hospital admissions for lung fibrosis/IPF.

This method could be used for future geographical healthcare planning.

doi.org/10.1183/2312...
Fine-scale regional frequency of the MUC5B promoter variant correlates with healthcare burden of idiopathic pulmonary fibrosis
ExtractThe gain-of-function MUC5B promoter variant n.661G>T (rs35705950) is a well-established common genetic risk factor for idiopathic pulmonary fibrosis (IPF) [1] and is present in over 50% of European-like ancestry patients with IPF. It also confers risk for other types of interstitial lung diseases (ILDs) with usual interstitial pneumonia pattern, including chronic hypersensitivity pneumonitis [2], asbestosis [3] and rheumatoid arthritis-associated ILD [4].
doi.org
September 24, 2025 at 12:21 PM
I totally agree.
Summaries may be fine for some forms of science communications but scientists need the detail to make up their minds on the veracity of claims in papers.
Reading papers is a basic skill (and dare I say duty?) of scientists, and I include medical doctors in that group. Keeping abreast of the literature is a foundational part of our professions. There aren’t good shortcuts. In any case, reading papers regularly is fun.
arstechnica.com/ai/2025/09/s...
Science journalists find ChatGPT is bad at summarizing scientific papers
LLM “tended to sacrifice accuracy for simplicity” when writing news briefs.
arstechnica.com
September 21, 2025 at 9:59 AM
Reposted by Killian Hurley
It is grossly irresponsible of Reform to platform such dangerous pseudoscience in the name of ‘free speech’.

Reform criticised over doctor's Covid jab claims at conference www.bbc.com/news/article...
Reform distances itself from doctor who made Covid claims at conference
A speaker at the Reform UK conference claimed it was "highly likely" that the jab was linked to the King and Princess of Wales' cancers.
www.bbc.com
September 7, 2025 at 4:15 AM
Reposted by Killian Hurley
September 3, 2025 at 2:36 PM
Reposted by Killian Hurley
9 CDC Directors going back to 1977 speak out. What RFK Jr has done to our nation’s public health system "should alarm every American."

It "is unlike anything we have ever seen at the agency, and unlike anything our country has ever experienced." www.nytimes.com/2025/09/01/o...
Opinion | We Ran the C.D.C.: Kennedy Is Endangering Every American’s Health
www.nytimes.com
September 1, 2025 at 11:23 AM
Reposted by Killian Hurley
Really cool: "Sex-biased Gene Expression Underlies Immune Dysfunction in Asthma "
Kudos Drs Kay and Gomez and team!!!
#DemistifyAsthma
www.atsjournals.org/doi/10.1165/...
@ajrcmb.bsky.social @yalepccsm.bsky.social
August 30, 2025 at 10:58 AM
Looks like telomere dysfunction is complex in mice and people
- needs more investigation and great science.
#Telomeres
#CureIPF
🧪
🧬
August 31, 2025 at 4:58 PM
Reposted by Killian Hurley
🫁 Listen up LUNG people! 🫁

Get your colleagues over here to #medsky and start posting and engaging! These breathing problems aren’t gonna fix themselves - we need engagement, knowledge sharing, and discussion! 🤩
Here is a full list of all #Medsky accounts by specialty:

Ophtho: 231
Geri: 310
Derm: 330
Rheum: 393
Urology: 432
Anesthesia: 493
Ob/Gyn: 505
Heme: 505
IM: 588
Neph: 878
Palliative: 882
Rads: 918
ID: 969
FM/PC: 1,102
Cards: 1,177
Surgery: 2,340
Psych: 2,441
Onc: 2,815
Immuno: 2,988
Peds: 2,999
August 27, 2025 at 4:25 AM
Reposted by Killian Hurley
​A new study reveals a shocking link between oil & gas air pollution and the health of our children. It's time to demand cleaner air for our families. #CleanAir #ClimateAction #ProtectOurKids #momsky

www.theguardian.com/us-news/2025...
Air pollution from oil and gas causes 90,000 premature US deaths each year, says new study
Study analyzed health impacts of fossil fuels from exploration to end use, and found communities of color bear brunt of harm
www.theguardian.com
August 24, 2025 at 5:46 PM
Reposted by Killian Hurley
The nicotine addiction industry always wants new victims. Why else sell bubblegum flavoured vapes?
www.theguardian.com/society/2025...
Third of UK teenagers who vape will go on to start smoking, research shows
Findings suggest e-cigarettes increasingly act as ‘gateway’ to nicotine for children, undermining earlier falling rates
www.theguardian.com
July 30, 2025 at 5:26 AM
Reposted by Killian Hurley
The air we breathe at work shouldn’t put our health at risk.

That’s why we propose new exposure limits for hazardous chemicals like cobalt, PAHs, 1,4-dioxane & welding fumes.

These measures could save €1.16B in healthcare costs & protect workers’ lives ↓

europa.eu/!mCQd69
July 18, 2025 at 12:01 PM
Reposted by Killian Hurley
We are delighted that RCSI is featured on the Sunday Times Ireland Best Places to Work 2025 list.

Organisations must have excellent scores across a six-step framework, including reward and recognition, well-being and job satisfaction.

🔗 www.thetimes.com/world/irelan... #BestPlacestoWork2025
July 14, 2025 at 9:35 AM
Delighted to give a talk at the Vermont Lung Stem Cell Conference last week.

Also got to visit with @kottond.bsky.social, Finn Hawkins, Joe Kaserman, and Kostas Alysandratos - all legends of the lung regeneration field at the CReM Boston University
@crem-boston.bsky.social

#CureIPF
July 14, 2025 at 5:30 PM
Reposted by Killian Hurley
Incidence, Prevalence, and Mortality of Interstitial Lung Diseases in Alberta, Canada: A Population-based Study

www.atsjournals.org/doi/suppl/10...

🧵👇

📣 TL:DR Incidence stable, prevalence rising, improved survival for ILD & IPF over 10 years.
Numbers much higher than prior reports for ILD & IPF.
July 4, 2025 at 2:35 PM
Dirty air is killing more than 500 people a week in the UK according to a Royal College of Physicians report.

This is a public health issue and not just an environmental one.

@royalcollege.bsky.social
@irishthoracicsoc.bsky.social
@ilfa-ireland.bsky.social

www.theguardian.com/environment/...
UK air pollution killing more than 500 people a week, doctors say
Royal College of Physicians also says poor air quality costs country more than £500m a week
www.theguardian.com
June 29, 2025 at 10:20 AM