Katia Faliti
@katyely.bsky.social
Immunologist interested in B and T cells in the GC ( and around it)
Human SLE, Autoimmunity and Vaccines
Currently Instructor at Emory, in the Sanz Lab 🧑🔬💉🔬
Human SLE, Autoimmunity and Vaccines
Currently Instructor at Emory, in the Sanz Lab 🧑🔬💉🔬
Pinned
Katia Faliti
@katyely.bsky.social
· Nov 16
Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE
Nature Immunology - SLE is a heterogeneous disorder that is characterized by different immune endotypes. Faliti et al. follow the immune memory responses upon mRNA COVID-19 vaccinations in a large...
rdcu.be
Our study just out!
"Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE".
🔗
* rdcu.be/dZWI9
* lnkd.in/desv-ZrV
#SLE | #Autoimmunity | #mRNAvaccines | Disease-associated #Bcells shape anti-vaccine immunity in SLE. 👩🔬 💉💉💉 🦠
"Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE".
🔗
* rdcu.be/dZWI9
* lnkd.in/desv-ZrV
#SLE | #Autoimmunity | #mRNAvaccines | Disease-associated #Bcells shape anti-vaccine immunity in SLE. 👩🔬 💉💉💉 🦠
Reposted by Katia Faliti
'In short, human genetics has become an evolutionary science in a way that can’t be undone. You cannot meaningfully study how humans function or differ from one another without understanding how evolution has shaped us.'
www.johnhawks.net/p/what-i-tol...
www.johnhawks.net/p/what-i-tol...
What I told my students about the threats to evolutionary science
I was floored by the question, but it matters. With U.S. funding crashing, what will happen to the future of the field?
www.johnhawks.net
May 4, 2025 at 6:10 PM
'In short, human genetics has become an evolutionary science in a way that can’t be undone. You cannot meaningfully study how humans function or differ from one another without understanding how evolution has shaped us.'
www.johnhawks.net/p/what-i-tol...
www.johnhawks.net/p/what-i-tol...
✈️ Don't miss this incredible opportunity! Join us for IMMUNOLOGY2025™ in Honolulu, HI and experience world-class science and island vibes. Early Bird ends tomorrow – register now: immunology2025.aai.org.
April 28, 2025 at 1:02 PM
Reposted by Katia Faliti
#Medsky🧪 #pedsky #immunosky #IDsky #publichealth Children under the age of five have an average incidence of 4 to 6 viral respiratory infections per year, which increases the risk of developing acute bacterial sinusitis or mastoiditis.
www.thelancet.com/journals/lan... @thelancetinfdis.bsky.social
www.thelancet.com/journals/lan... @thelancetinfdis.bsky.social
Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
The findings of this study highlight the widespread burden posed by URIs and otitis
media across all age groups and both sexes. There is a continued need for surveillance,
prevention, and management t...
www.thelancet.com
April 23, 2025 at 4:37 AM
#Medsky🧪 #pedsky #immunosky #IDsky #publichealth Children under the age of five have an average incidence of 4 to 6 viral respiratory infections per year, which increases the risk of developing acute bacterial sinusitis or mastoiditis.
www.thelancet.com/journals/lan... @thelancetinfdis.bsky.social
www.thelancet.com/journals/lan... @thelancetinfdis.bsky.social
Reposted by Katia Faliti
Delighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it #microbiome #science #immunology
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Bifidobacteria support optimal infant vaccine responses - Nature
Neonatal antibiotic use is shown to reduce immune response to infant vaccines, accompanied by reduced abundance of Bifidobacteria in the gut microbiota, with experiments in mice indicating that probio...
www.nature.com
April 2, 2025 at 11:33 PM
Delighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it #microbiome #science #immunology
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Katia Faliti
Letting mice experience the "wild" alters their immune system, especially their B-cells! Also, we talk to an organizer of the Atlanta #standupforscience2025 about his experience 🧪
www.youtube.com/watch?v=7Hgo...
www.youtube.com/watch?v=7Hgo...
Episode 36 - Mice touching grass
YouTube video by Audiommunity
www.youtube.com
March 18, 2025 at 4:02 PM
Letting mice experience the "wild" alters their immune system, especially their B-cells! Also, we talk to an organizer of the Atlanta #standupforscience2025 about his experience 🧪
www.youtube.com/watch?v=7Hgo...
www.youtube.com/watch?v=7Hgo...
Reposted by Katia Faliti
'The scale of disruption to science funding in the USA is unprecedented. At the NIH, study sections, funding councils and project meetings have been cancelled. Without these, new grants cannot be funded or renewed. Fellowship programs have been cancelled.'
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
Science under siege: protecting scientific progress in turbulent times
As Editors-in-Chief of The Company of Biologists' journals, we have been watching with growing concern the policy changes in the United States of America (USA) and the challenges that these are creati...
journals.biologists.com
March 14, 2025 at 8:37 AM
'The scale of disruption to science funding in the USA is unprecedented. At the NIH, study sections, funding councils and project meetings have been cancelled. Without these, new grants cannot be funded or renewed. Fellowship programs have been cancelled.'
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
Reposted by Katia Faliti
So, not to diminish that this is a good thing but... we still don't know who they'll nominate in his place.
Wowoowowowowowwowowwowowo @defendpublichealth.bsky.social THIS IS A WIN FOR PUBLIC HEALTH!!!!!
White House pulls nomination of Dave Weldon as CDC director hours before hearing
The White House has pulled the nomination of Dave Weldon as CDC director hours before heh was set to appear for his confirmation hearing.
www.statnews.com
March 13, 2025 at 1:26 PM
So, not to diminish that this is a good thing but... we still don't know who they'll nominate in his place.
Reposted by Katia Faliti
‘One last thing’: Trudeau posts message to Canadians on final day as prime minister #Canada #cdnpoli #ThankYouPMTrudeau 🍁💪🏻
www.ctvnews.ca/politics/art...
www.ctvnews.ca/politics/art...
‘One last thing’: Trudeau posts message to Canadians on final day as prime minister
Prime Minister Justin Trudeau says Canadians are great and shouldn’t change, in a final message posted from his office on his last day in it.
www.ctvnews.ca
March 13, 2025 at 8:28 PM
‘One last thing’: Trudeau posts message to Canadians on final day as prime minister #Canada #cdnpoli #ThankYouPMTrudeau 🍁💪🏻
www.ctvnews.ca/politics/art...
www.ctvnews.ca/politics/art...
Reposted by Katia Faliti
I refuse to accept a post-truth reality where knowledge and humanity no longer matter. Stand up for Science!! #standupforscience
March 4, 2025 at 4:32 AM
I refuse to accept a post-truth reality where knowledge and humanity no longer matter. Stand up for Science!! #standupforscience
Reposted by Katia Faliti
Yeah, this 100%
Graduating during the pandemic slowed down my process and is part of why I did two postdocs. Now as a first year faculty, all the federal grants are frozen. I love the work I do but this has all of us questioning how much www.science.org/content/arti...
U.S. early-career researchers struggling amid chaos
Uncertain funding, government firings, and distressed universities hit vulnerable groups especially hard
www.science.org
February 25, 2025 at 12:22 AM
Yeah, this 100%
Reposted by Katia Faliti
🚨BREAKING: Federal Court GRANTS sweeping nationwide injunction against Trump DEI executive orders finding that they violate First and Fifth Amendments to the Constitution. A huge victory for @democracyforward.org and its clients. A stinging loss for Trump.
Visit www.democracydocket.com for details.
Visit www.democracydocket.com for details.
February 21, 2025 at 11:39 PM
🚨BREAKING: Federal Court GRANTS sweeping nationwide injunction against Trump DEI executive orders finding that they violate First and Fifth Amendments to the Constitution. A huge victory for @democracyforward.org and its clients. A stinging loss for Trump.
Visit www.democracydocket.com for details.
Visit www.democracydocket.com for details.
Reposted by Katia Faliti
Cool paper from the Davis lab using human tonsil organoids to study CD4 and CD8 Tregs. Even though subjects with autoimmunity were excluded, organoids derived from female donors had higher autoreactivity, providing an ex vivo system to study sex differences in response to self antigens. #ImmunoSky 🧪
Differential roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses - Nature Immunology
Here the authors use a tonsil organoid culture model system to investigate the roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses. CD4+ regulatory T cells we...
www.nature.com
February 18, 2025 at 4:33 PM
Cool paper from the Davis lab using human tonsil organoids to study CD4 and CD8 Tregs. Even though subjects with autoimmunity were excluded, organoids derived from female donors had higher autoreactivity, providing an ex vivo system to study sex differences in response to self antigens. #ImmunoSky 🧪
Darkest of times... #ImmunoSky
First they came for the DEI programs, and I did not speak out, because I'm a white guy.
Then they came for the scientists, and... Fuck, that was fast
Then they came for the scientists, and... Fuck, that was fast
🧪 More information about the #Standupforscience event in this interview with the lead organizer @cdelawalla.bsky.social
and the reasons why the rally is taking place (March 7, DC and near you).
youtu.be/tfNtuhNAxlw?...
and the reasons why the rally is taking place (March 7, DC and near you).
youtu.be/tfNtuhNAxlw?...
February 17, 2025 at 12:03 AM
Darkest of times... #ImmunoSky
Reposted by Katia Faliti
We have to fight now for research that we know benefits all of humanity, we have to stand up for our colleagues at the NIH, we can’t lie down and take it, we stand against this madness #standupforscience2025
Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
February 15, 2025 at 11:28 PM
We have to fight now for research that we know benefits all of humanity, we have to stand up for our colleagues at the NIH, we can’t lie down and take it, we stand against this madness #standupforscience2025
Reposted by Katia Faliti
@katherinejwu.com getting straight to the ❤️ of the crisis. This current attack on science must be stopped to protect all Americans.
An absolute must-read from @katherinejwu.com on the rapid destruction of American science: www.theatlantic.com/health/archi...
The Erasing of American Science
How far can the Trump administration bend U.S. research before it breaks?
www.theatlantic.com
February 15, 2025 at 10:15 PM
@katherinejwu.com getting straight to the ❤️ of the crisis. This current attack on science must be stopped to protect all Americans.
Reposted by Katia Faliti
My weekend with immunologists devising new strategies to treat cancer, allergy, Alzheimer’s, autoimmunity and infection. The WH has just paused peer-reviewed NIH funding that pays for these studies. If you care about human life, write your representatives. Demand that NIH funding is restored asap.
January 28, 2025 at 5:27 AM
My weekend with immunologists devising new strategies to treat cancer, allergy, Alzheimer’s, autoimmunity and infection. The WH has just paused peer-reviewed NIH funding that pays for these studies. If you care about human life, write your representatives. Demand that NIH funding is restored asap.
Reposted by Katia Faliti
Reposted by Katia Faliti
Talk to your department chairs and research offices! 🧪
Per an NIH source:
“Discussions with colleagues have suggested that if the universities all come together and raise hell about the delays to funding caused by not holding meetings, that might move the needle. From every state. There are well-funded universities in red states that will be impacted.”
“Discussions with colleagues have suggested that if the universities all come together and raise hell about the delays to funding caused by not holding meetings, that might move the needle. From every state. There are well-funded universities in red states that will be impacted.”
January 28, 2025 at 1:35 AM
Talk to your department chairs and research offices! 🧪
Thank you
@emoryuniversity.bsky.social
for highlighting our recent study in NI! @natureportfolio.bsky.social (we did not make it to cover selection, but I love it anyway) #immunoSky
Links url:https://news.emory.edu/stories/2025/01/er_lupus_and_mrna_15_01_2025/story.html
rdcu.be/dZWI9
rdcu.be/d4332
@emoryuniversity.bsky.social
for highlighting our recent study in NI! @natureportfolio.bsky.social (we did not make it to cover selection, but I love it anyway) #immunoSky
Links url:https://news.emory.edu/stories/2025/01/er_lupus_and_mrna_15_01_2025/story.html
rdcu.be/dZWI9
rdcu.be/d4332
January 23, 2025 at 4:56 PM
Thank you
@emoryuniversity.bsky.social
for highlighting our recent study in NI! @natureportfolio.bsky.social (we did not make it to cover selection, but I love it anyway) #immunoSky
Links url:https://news.emory.edu/stories/2025/01/er_lupus_and_mrna_15_01_2025/story.html
rdcu.be/dZWI9
rdcu.be/d4332
@emoryuniversity.bsky.social
for highlighting our recent study in NI! @natureportfolio.bsky.social (we did not make it to cover selection, but I love it anyway) #immunoSky
Links url:https://news.emory.edu/stories/2025/01/er_lupus_and_mrna_15_01_2025/story.html
rdcu.be/dZWI9
rdcu.be/d4332
Congrats @kevbonham.bsky.social! Great news! They are lucky to have you! Looking forward for exciting collaborations :) #immunoSky
Very excited to announce that the Bonham Lab will be starting next month at Tufts (TMC GI division)!
I'll be recruiting at multiple levels - if you are interested in the intersection between computing and medicine, esp multi-'omics, microbio and immuno, reach out! #academicsky 🧪🧫🦠
I'll be recruiting at multiple levels - if you are interested in the intersection between computing and medicine, esp multi-'omics, microbio and immuno, reach out! #academicsky 🧪🧫🦠
Department of Medicine | Tufts Medicine
Access comprehensive care at Tufts Medical Center's Department of Medicine. Our experts provide personalized treatment for a range of conditions.
www.tuftsmedicine.org
January 17, 2025 at 9:11 PM
Congrats @kevbonham.bsky.social! Great news! They are lucky to have you! Looking forward for exciting collaborations :) #immunoSky
Reposted by Katia Faliti
New! @jenncoughlan.bsky.social kindly shared their MIRA NIH award with our github repo. If you have a successful grant app you're willing to share, please contribute! github.com/RILAB/statem...
GitHub - RILAB/statements: Successful Job Applications and Grants
Successful Job Applications and Grants. Contribute to RILAB/statements development by creating an account on GitHub.
github.com
December 31, 2024 at 9:38 PM
New! @jenncoughlan.bsky.social kindly shared their MIRA NIH award with our github repo. If you have a successful grant app you're willing to share, please contribute! github.com/RILAB/statem...
Fantastic News & Views article Nature Portfolio by @michelalocci.bsky.social & @sapostolidis.bsky.social, highlighting our recent study on mRNA vaccines and SLE, its findings, and the key questions to address next!
rdcu.be/d4332
#immunosky #SLE #mRNA #Bcells 🦠 👩🔬 💉
rdcu.be/d4332
#immunosky #SLE #mRNA #Bcells 🦠 👩🔬 💉
SLE B cells take an extrafollicular detour after mRNA vaccination
Nature Immunology - Systemic lupus erythematosus (SLE) is an autoimmune disease with considerable clinical heterogeneity and diverse treatment options. A study now shows that heightened...
rdcu.be
December 28, 2024 at 11:08 AM
Fantastic News & Views article Nature Portfolio by @michelalocci.bsky.social & @sapostolidis.bsky.social, highlighting our recent study on mRNA vaccines and SLE, its findings, and the key questions to address next!
rdcu.be/d4332
#immunosky #SLE #mRNA #Bcells 🦠 👩🔬 💉
rdcu.be/d4332
#immunosky #SLE #mRNA #Bcells 🦠 👩🔬 💉
@johnmlindner.bsky.social It was a pleasure hosting you at
#Emory! Thanks for sharing your remarkable insights into the T-Finder discovery pipeline. Excited for the collaborations ahead in T cells, B cells, and to more adventures in Atlanta’s diners with you and @eliverghosn.bsky.social #immunosky
#Emory! Thanks for sharing your remarkable insights into the T-Finder discovery pipeline. Excited for the collaborations ahead in T cells, B cells, and to more adventures in Atlanta’s diners with you and @eliverghosn.bsky.social #immunosky
December 15, 2024 at 8:19 PM
@johnmlindner.bsky.social It was a pleasure hosting you at
#Emory! Thanks for sharing your remarkable insights into the T-Finder discovery pipeline. Excited for the collaborations ahead in T cells, B cells, and to more adventures in Atlanta’s diners with you and @eliverghosn.bsky.social #immunosky
#Emory! Thanks for sharing your remarkable insights into the T-Finder discovery pipeline. Excited for the collaborations ahead in T cells, B cells, and to more adventures in Atlanta’s diners with you and @eliverghosn.bsky.social #immunosky
Dr Kuchroo discussing the discovery and properties of TIM-3 and Tcf1 on T cells and beyond!
@emoryuniversity.bsky.social #treg #dc #tim-3 #ImmunoSky
@emoryuniversity.bsky.social #treg #dc #tim-3 #ImmunoSky
December 4, 2024 at 11:15 PM
Dr Kuchroo discussing the discovery and properties of TIM-3 and Tcf1 on T cells and beyond!
@emoryuniversity.bsky.social #treg #dc #tim-3 #ImmunoSky
@emoryuniversity.bsky.social #treg #dc #tim-3 #ImmunoSky
Totally agree! Fantastic scientist and human being!
Max deserves a Nobel. In the meantime, you can nominate someone for the Max Cooper Prize, deadline is April 1st.
"Nomination letters of up to 3 pages must articulate how their research has led to advances in immunology research that will have a lasting impact."
#Immunology
"Nomination letters of up to 3 pages must articulate how their research has led to advances in immunology research that will have a lasting impact."
#Immunology
Emory Max Cooper Prize in Immunology | Emory School of MedicineToggleToggleToggleToggleSearchCloseSearch
SearchToggle openToggle closeSub linkSub linkSub linkSub linkSub linkSub linkToggle openToggle ...
med.emory.edu
December 4, 2024 at 11:12 PM
Totally agree! Fantastic scientist and human being!