JN117
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JN117
@jn117.bsky.social
78 followers 180 following 410 posts
I am a layman. I am interested in science, engineering, immunology, virology, COVID, and Long Covid. I am very grateful to researchers who are working to help us understand infection-associated chronic conditions.
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Reposted by JN117
erictopol.bsky.social
Our randomized, placebo-controlled trial of tirzepatide (Zepbound) for #LongCovid has already enrolled 500 participants of 1000 planned in less than 2 weeks!
longcovid.scripps.edu/locitt-t/
LoCITT-T - Long COVID Treatment Trial
The Long COVID Treatment Trial-Tirzepatide (LoCITT-T) is investigating the efficacy of repurposing this drug to treat Long COVID.
longcovid.scripps.edu
November 13, 2025 at 3:21 PM
October 27, 2027 -- FlowFlex introduced first US-approved RSV+Flu+COVID home test. Product is made in their new San Diego, CA facility.
Press release:
www.aconlabs.com/acon-laborat...

@danielgriffinmdphd.bsky.social
November 12, 2025 at 3:22 PM
Reposted by JN117
bhanlon15.bsky.social
Healio: 'Antivirals reduce long COVID incidence at 90 days in patients with rheumatic diseases'

www.healio.com/news/rheumat...
Antivirals reduce long COVID incidence at 90 days in patients with rheumatic diseases
CHICAGO — Patients with autoimmune and rheumatic diseases who received antiviral therapy for COVID-19 demonstrated reduced incidence of long COVID symptoms at 90 days post infection, according t...
www.healio.com
October 29, 2025 at 7:29 PM
The rate of motor vehicle fatalities has return to pre-pandemic rates.
www.nhtsa.gov/press-releas...
October 17, 2025 at 12:04 PM
Wow.
Incidence rate (IR) of POTS (Postural Orthostatic Tachycardia Syndrome) over time.

IR was 1.42 per 1 million person-years before COVID and 20.3 cases per 1 million person-years after COVID began.
October 14, 2025 at 2:27 PM
I think this might be the first head-to-head trial of Paxlovid versus Xocova (Ensitrelvir). Seems randomized but open-label.
They find faster viral clearance with Paxlovid. Similar viral rebound rates (7% versus 5%).
www.thelancet.com/journals/lan...
October 13, 2025 at 8:49 PM
Health-related absences from work are still elevated compared to pre-pandemic. There is an association between SARS-CoV-2 wastewater levels and absences from work.
jamanetwork.com/journals/jam...
Enduring Outcomes of COVID-19 Work Absences on the US Labor Market
This cohort study examines the extent to which COVID-19 continues to generate work absences and decrease labor force participation beyond the pandemic period in the US.
jamanetwork.com
October 12, 2025 at 1:36 PM
President Trump got flu and COVID-19 vaccines today.

x.com/kaitlancolli...
October 11, 2025 at 1:32 AM
Reposted by JN117
kidneyboy.bsky.social
Can’t stop staring at the prevalence of hypertension among young people.

www.ahajournals.org/doi/epub/10....
October 9, 2025 at 12:25 PM
Invivyd announces FDA clearance for new Phase 3 clinical trials for intramuscular monoclonals for prevention of COVID.
investors.invivyd.com/news-release...
October 6, 2025 at 3:14 PM
Percent of hospital and ICU beds occupied by RSV, Flu, and COVID patients remains the same as 2 weeks ago, except for COVID, where hospital beds decreased by 0.1%.
There is also a new graph of new hospital admissions by virus.

www.cdc.gov/nhsn/psc/hos...
October 3, 2025 at 5:47 PM
CDC seems to think 3x to 4x more Flu illnesses than COVID ?

This was the first season CDC attempted to make in-season estimates of disease burden of the "big 3" RSV, Flu, and COVID. RSV and Flu updates went through May, but COVID estimates continued all year.

www.cdc.gov/covid/php/su...
October 2, 2025 at 2:37 PM
Study of vaccine effectiveness against Long COVID finds rates of Long Covid (self-reported symptoms persisting >12 weeks) of ~10-20% after first infection and ~10% of re-infections.

pubmed.ncbi.nlm.nih.gov/41021660/
September 30, 2025 at 2:51 PM
Deaths involving COVID-19 in preceding 52 weeks

Rolling 52-week cumulative deaths dropped below 100,000 for the first time the week of December 21, 2024. 52 weeks preceding 9/20/2025 had 60,891 COVD deaths.

Source: National Center for Health Statistics
data.cdc.gov/National-Cen...
September 30, 2025 at 1:56 PM
Science is how we learn new things.
Like a treatment for a disease that has never been treatable in all human history.

www.bbc.com/news/article...
Huntington's disease successfully treated for first time
One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.
www.bbc.com
September 24, 2025 at 8:51 PM
For the first time in 5 years, COVID-19 is not among the Top 15 leading causes of death.

Here is 2024 (whole year) versus 2025 (partial year).

This is the CDC wonder query link that will run the Top 15 leading causes of death query with up-to-date provisional data.
wonder.cdc.gov/controller/s...
September 23, 2025 at 4:31 PM
Hospital bed occupancy did not change this week for any of the three monitored illnesses (COVID-19, Influenza, and RSV).
A leveling-off/peak is probably occurring.
www.cdc.gov/nhsn/psc/hos...
September 21, 2025 at 6:54 PM
The 2024 BRFSS questionnaire removed questions about COVID & Long COVID.
BRFSS is a large (>200K) live telephone survey about health and health conditions. I am not aware of any recurring survey measuring self-reported Long COVID any more.
www.cdc.gov/brfss/annual...
September 15, 2025 at 7:39 PM
Chronic illness can be caused by breathing contaminants in airplane cabin air.
(Professor Marr made this a gift link so all can read.)
September 15, 2025 at 12:25 PM
Reposted by JN117
bhanlon15.bsky.social
UAB: “SARS-CoV-2 drives lung foam cell formation linked to long-COVID damage, study finds”

“Approximately 15 million to 20 million Americans who have acquired COVID-19 experience persistent symptoms lasting over three months, known as long COVID”

www.uab.edu/news/researc...
SARS-CoV-2 drives lung foam cell formation linked to long-COVID damage, study finds
SARS-CoV-2 drives lung foam cell formation linked to long-COVID damage, study finds
www.uab.edu
September 13, 2025 at 5:23 AM
In 2023, there were 770 traffic fatalities in children <=14 years in the USA.

crashstats.nhtsa.dot.gov/Api/Public/V...
September 12, 2025 at 9:50 PM
ICU bed occupancy for COVID increased 0.1% in the last week. Hospital bed occupancy increased 0.2%. This level of COVID hospitalization was last seen March 1, 2025.
Flu and RSV were unchanged from previous week.
www.cdc.gov/respiratory-...
September 12, 2025 at 7:47 PM
Reposted by JN117
chantzy.bsky.social
Covid has killed ~5-6x the number of people this year as those who died in 9-11. Both are heartbreaking, ❤️‍🩹 but only one is grieved publicly. The other is barely noticed & declared over
September 11, 2025 at 2:59 PM
If the same thing happened in the USA, I wonder if we would be as quick and efficient as the National Biomedical Research Institute (INRB) of the Democratic Republic of the Congo was in releasing this detailed information about a new ebola spillover.
angierasmussen.bsky.social Angie Rasmussen @angierasmussen.bsky.social · Sep 5
This is how outbreak response should go: fast, transparent, and actionable.

Ebola will continue to spill over into humans. So will other viruses, some new, some old. Having this response capacity is what controls outbreaks, stops epidemics, & saves lives.
kakape.bsky.social Kai Kupferschmidt @kakape.bsky.social · Sep 5
Sequence data from the new Ebola outbreak in DRC suggests it is indeed a new spillover.

And just incredible to see the virus sequenced and the data publicly shared less than 24 hours after confirmation of the outbreak.
#IDsky 🧪

virological.org/t/the-16th-e...
September 5, 2025 at 9:10 PM
ICU bed occupancy for COVID increased 0.2% in the last week. Hospital bed occupancy increased 0.1%. Flu and RSV were unchanged from previous week.
www.cdc.gov/nhsn/psc/hos...
September 5, 2025 at 6:00 PM