JN117
@jn117.bsky.social
I am a layman. I am interested in science, engineering, immunology, virology, COVID, and Long Covid. I am very grateful to researchers who are working to help us understand infection-associated chronic conditions.
In clinical testing, the RSV test had 94% positive agreement with PCR for subjects within 5 days of symptom onset.
www.accessdata.fda.gov/cdrh_docs/re...
www.accessdata.fda.gov/cdrh_docs/re...
November 12, 2025 at 3:22 PM
In clinical testing, the RSV test had 94% positive agreement with PCR for subjects within 5 days of symptom onset.
www.accessdata.fda.gov/cdrh_docs/re...
www.accessdata.fda.gov/cdrh_docs/re...
Interestingly, the test is licensed for people 6 months and older, so it includes a swab guard to prevent the swab from going deeper than intended.
November 12, 2025 at 3:22 PM
Interestingly, the test is licensed for people 6 months and older, so it includes a swab guard to prevent the swab from going deeper than intended.
Unfortunately, no pictures of the actual test cartridge, but the FDA summary of decision shows some diagrams. It has two side-by-side test strips--one with Flu & COVID and the other with RSV.
www.accessdata.fda.gov/cdrh_docs/re...
www.accessdata.fda.gov/cdrh_docs/re...
November 12, 2025 at 3:22 PM
Unfortunately, no pictures of the actual test cartridge, but the FDA summary of decision shows some diagrams. It has two side-by-side test strips--one with Flu & COVID and the other with RSV.
www.accessdata.fda.gov/cdrh_docs/re...
www.accessdata.fda.gov/cdrh_docs/re...
October 27, 2027 -- FlowFlex introduced first US-approved RSV+Flu+COVID home test. Product is made in their new San Diego, CA facility.
Press release:
www.aconlabs.com/acon-laborat...
@danielgriffinmdphd.bsky.social
Press release:
www.aconlabs.com/acon-laborat...
@danielgriffinmdphd.bsky.social
November 12, 2025 at 3:22 PM
October 27, 2027 -- FlowFlex introduced first US-approved RSV+Flu+COVID home test. Product is made in their new San Diego, CA facility.
Press release:
www.aconlabs.com/acon-laborat...
@danielgriffinmdphd.bsky.social
Press release:
www.aconlabs.com/acon-laborat...
@danielgriffinmdphd.bsky.social
"there's been an illness going around..."
November 5, 2025 at 6:49 PM
"there's been an illness going around..."
The rate of motor vehicle fatalities has return to pre-pandemic rates.
www.nhtsa.gov/press-releas...
www.nhtsa.gov/press-releas...
October 17, 2025 at 12:04 PM
The rate of motor vehicle fatalities has return to pre-pandemic rates.
www.nhtsa.gov/press-releas...
www.nhtsa.gov/press-releas...
Wow.
Incidence rate (IR) of POTS (Postural Orthostatic Tachycardia Syndrome) over time.
IR was 1.42 per 1 million person-years before COVID and 20.3 cases per 1 million person-years after COVID began.
Incidence rate (IR) of POTS (Postural Orthostatic Tachycardia Syndrome) over time.
IR was 1.42 per 1 million person-years before COVID and 20.3 cases per 1 million person-years after COVID began.
October 14, 2025 at 2:27 PM
Wow.
Incidence rate (IR) of POTS (Postural Orthostatic Tachycardia Syndrome) over time.
IR was 1.42 per 1 million person-years before COVID and 20.3 cases per 1 million person-years after COVID began.
Incidence rate (IR) of POTS (Postural Orthostatic Tachycardia Syndrome) over time.
IR was 1.42 per 1 million person-years before COVID and 20.3 cases per 1 million person-years after COVID began.
I think this might be the first head-to-head trial of Paxlovid versus Xocova (Ensitrelvir). Seems randomized but open-label.
They find faster viral clearance with Paxlovid. Similar viral rebound rates (7% versus 5%).
www.thelancet.com/journals/lan...
They find faster viral clearance with Paxlovid. Similar viral rebound rates (7% versus 5%).
www.thelancet.com/journals/lan...
October 13, 2025 at 8:49 PM
I think this might be the first head-to-head trial of Paxlovid versus Xocova (Ensitrelvir). Seems randomized but open-label.
They find faster viral clearance with Paxlovid. Similar viral rebound rates (7% versus 5%).
www.thelancet.com/journals/lan...
They find faster viral clearance with Paxlovid. Similar viral rebound rates (7% versus 5%).
www.thelancet.com/journals/lan...
October 11, 2025 at 1:32 AM
The BIOFIRE respiratory panel tests for presence of ~22 pathogens at once. Most of the time, rhinovirus is detected more often than COVID. I suspect BIOFIRE is mostly used on inpatients, but I don't know for sure.
syndromictrends.com
syndromictrends.com
October 7, 2025 at 3:00 AM
The BIOFIRE respiratory panel tests for presence of ~22 pathogens at once. Most of the time, rhinovirus is detected more often than COVID. I suspect BIOFIRE is mostly used on inpatients, but I don't know for sure.
syndromictrends.com
syndromictrends.com
Invivyd announces FDA clearance for new Phase 3 clinical trials for intramuscular monoclonals for prevention of COVID.
investors.invivyd.com/news-release...
investors.invivyd.com/news-release...
October 6, 2025 at 3:14 PM
Invivyd announces FDA clearance for new Phase 3 clinical trials for intramuscular monoclonals for prevention of COVID.
investors.invivyd.com/news-release...
investors.invivyd.com/news-release...
Percent of hospital and ICU beds occupied by RSV, Flu, and COVID patients remains the same as 2 weeks ago, except for COVID, where hospital beds decreased by 0.1%.
There is also a new graph of new hospital admissions by virus.
www.cdc.gov/nhsn/psc/hos...
There is also a new graph of new hospital admissions by virus.
www.cdc.gov/nhsn/psc/hos...
October 3, 2025 at 5:47 PM
Percent of hospital and ICU beds occupied by RSV, Flu, and COVID patients remains the same as 2 weeks ago, except for COVID, where hospital beds decreased by 0.1%.
There is also a new graph of new hospital admissions by virus.
www.cdc.gov/nhsn/psc/hos...
There is also a new graph of new hospital admissions by virus.
www.cdc.gov/nhsn/psc/hos...
FYI: Pfizer study on "rebound" (their word).
academic.oup.com/cid/advance-...
academic.oup.com/cid/advance-...
October 3, 2025 at 2:05 AM
FYI: Pfizer study on "rebound" (their word).
academic.oup.com/cid/advance-...
academic.oup.com/cid/advance-...
CDC seems to think 3x to 4x more Flu illnesses than COVID ?
This was the first season CDC attempted to make in-season estimates of disease burden of the "big 3" RSV, Flu, and COVID. RSV and Flu updates went through May, but COVID estimates continued all year.
www.cdc.gov/covid/php/su...
This was the first season CDC attempted to make in-season estimates of disease burden of the "big 3" RSV, Flu, and COVID. RSV and Flu updates went through May, but COVID estimates continued all year.
www.cdc.gov/covid/php/su...
October 2, 2025 at 2:37 PM
CDC seems to think 3x to 4x more Flu illnesses than COVID ?
This was the first season CDC attempted to make in-season estimates of disease burden of the "big 3" RSV, Flu, and COVID. RSV and Flu updates went through May, but COVID estimates continued all year.
www.cdc.gov/covid/php/su...
This was the first season CDC attempted to make in-season estimates of disease burden of the "big 3" RSV, Flu, and COVID. RSV and Flu updates went through May, but COVID estimates continued all year.
www.cdc.gov/covid/php/su...
Maybe it is the T cells reducing mortality from the virus.
Rolling 52-week cumulative deaths dropped below 100,000 for the first time the week of December 21, 2024. 52 weeks preceding 9/20/2025 had 60,891 COVD deaths.
Source:
data.cdc.gov/National-Cen...
Rolling 52-week cumulative deaths dropped below 100,000 for the first time the week of December 21, 2024. 52 weeks preceding 9/20/2025 had 60,891 COVD deaths.
Source:
data.cdc.gov/National-Cen...
October 1, 2025 at 3:29 PM
Maybe it is the T cells reducing mortality from the virus.
Rolling 52-week cumulative deaths dropped below 100,000 for the first time the week of December 21, 2024. 52 weeks preceding 9/20/2025 had 60,891 COVD deaths.
Source:
data.cdc.gov/National-Cen...
Rolling 52-week cumulative deaths dropped below 100,000 for the first time the week of December 21, 2024. 52 weeks preceding 9/20/2025 had 60,891 COVD deaths.
Source:
data.cdc.gov/National-Cen...
Study of vaccine effectiveness against Long COVID finds rates of Long Covid (self-reported symptoms persisting >12 weeks) of ~10-20% after first infection and ~10% of re-infections.
pubmed.ncbi.nlm.nih.gov/41021660/
pubmed.ncbi.nlm.nih.gov/41021660/
September 30, 2025 at 2:51 PM
Study of vaccine effectiveness against Long COVID finds rates of Long Covid (self-reported symptoms persisting >12 weeks) of ~10-20% after first infection and ~10% of re-infections.
pubmed.ncbi.nlm.nih.gov/41021660/
pubmed.ncbi.nlm.nih.gov/41021660/
Deaths involving COVID-19 in preceding 52 weeks
Rolling 52-week cumulative deaths dropped below 100,000 for the first time the week of December 21, 2024. 52 weeks preceding 9/20/2025 had 60,891 COVD deaths.
Source: National Center for Health Statistics
data.cdc.gov/National-Cen...
Rolling 52-week cumulative deaths dropped below 100,000 for the first time the week of December 21, 2024. 52 weeks preceding 9/20/2025 had 60,891 COVD deaths.
Source: National Center for Health Statistics
data.cdc.gov/National-Cen...
September 30, 2025 at 1:56 PM
Deaths involving COVID-19 in preceding 52 weeks
Rolling 52-week cumulative deaths dropped below 100,000 for the first time the week of December 21, 2024. 52 weeks preceding 9/20/2025 had 60,891 COVD deaths.
Source: National Center for Health Statistics
data.cdc.gov/National-Cen...
Rolling 52-week cumulative deaths dropped below 100,000 for the first time the week of December 21, 2024. 52 weeks preceding 9/20/2025 had 60,891 COVD deaths.
Source: National Center for Health Statistics
data.cdc.gov/National-Cen...
For the first time in 5 years, COVID-19 is not among the Top 15 leading causes of death.
Here is 2024 (whole year) versus 2025 (partial year).
This is the CDC wonder query link that will run the Top 15 leading causes of death query with up-to-date provisional data.
wonder.cdc.gov/controller/s...
Here is 2024 (whole year) versus 2025 (partial year).
This is the CDC wonder query link that will run the Top 15 leading causes of death query with up-to-date provisional data.
wonder.cdc.gov/controller/s...
September 23, 2025 at 4:31 PM
For the first time in 5 years, COVID-19 is not among the Top 15 leading causes of death.
Here is 2024 (whole year) versus 2025 (partial year).
This is the CDC wonder query link that will run the Top 15 leading causes of death query with up-to-date provisional data.
wonder.cdc.gov/controller/s...
Here is 2024 (whole year) versus 2025 (partial year).
This is the CDC wonder query link that will run the Top 15 leading causes of death query with up-to-date provisional data.
wonder.cdc.gov/controller/s...
Hospital bed occupancy did not change this week for any of the three monitored illnesses (COVID-19, Influenza, and RSV).
A leveling-off/peak is probably occurring.
www.cdc.gov/nhsn/psc/hos...
A leveling-off/peak is probably occurring.
www.cdc.gov/nhsn/psc/hos...
September 21, 2025 at 6:54 PM
Hospital bed occupancy did not change this week for any of the three monitored illnesses (COVID-19, Influenza, and RSV).
A leveling-off/peak is probably occurring.
www.cdc.gov/nhsn/psc/hos...
A leveling-off/peak is probably occurring.
www.cdc.gov/nhsn/psc/hos...
Regarding mortality <30 days after COVID vaccination, I've always liked this clever Qatar study of ~7 million COVID vax doses. They looked at EVERY DEATH that occurred <30 days of a COVID shot. They found very low mortality, about 1 in 100,000 recipients.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
September 15, 2025 at 8:44 PM
Regarding mortality <30 days after COVID vaccination, I've always liked this clever Qatar study of ~7 million COVID vax doses. They looked at EVERY DEATH that occurred <30 days of a COVID shot. They found very low mortality, about 1 in 100,000 recipients.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Here were the 2023 questions.
September 15, 2025 at 7:44 PM
Here were the 2023 questions.
The 2024 BRFSS questionnaire removed questions about COVID & Long COVID.
BRFSS is a large (>200K) live telephone survey about health and health conditions. I am not aware of any recurring survey measuring self-reported Long COVID any more.
www.cdc.gov/brfss/annual...
BRFSS is a large (>200K) live telephone survey about health and health conditions. I am not aware of any recurring survey measuring self-reported Long COVID any more.
www.cdc.gov/brfss/annual...
September 15, 2025 at 7:39 PM
The 2024 BRFSS questionnaire removed questions about COVID & Long COVID.
BRFSS is a large (>200K) live telephone survey about health and health conditions. I am not aware of any recurring survey measuring self-reported Long COVID any more.
www.cdc.gov/brfss/annual...
BRFSS is a large (>200K) live telephone survey about health and health conditions. I am not aware of any recurring survey measuring self-reported Long COVID any more.
www.cdc.gov/brfss/annual...