Jonathan C. Lau
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jclauneuro.bsky.social
Jonathan C. Lau
@jclauneuro.bsky.social
Neurosurgeon. Anatomy • Informatics • Modulation • Surgery. AIMS Lab.🧠🎯
Collaborative Medicine. Collaborative Science. Multisport.🏊🚴🏃
https://jclauneurolab.io
So proud of @alaat.bsky.social for successfully defending his thesis. First PhD grad of the AIMS lab! 🎯

Incredibly fortunate to work with him & @neuroak.bsky.social on AFIDs project.

Thanks also to examiners DrEmmaDuerden DrSarahMattonen @angelarobertsphd.bsky.social @emiddlebrooksmd.bsky.social 🙏
July 22, 2025 at 10:01 PM
Standing room only for @emiddlebrooksmd.bsky.social talk on Clinical Applications of 7T -- a special summer grand rounds
@WesternU CNS!

Incredible work @mayoclinic.org integrating 7T.

Thanks for the visit, and examining @alaat.bsky.social's thesis!
July 22, 2025 at 9:45 PM
Reposted by Jonathan C. Lau
Tuesday July 22, Dr. Erik H. Middlebrooks from the @mayoclinic.org will be giving a seminar entitled "Clinical Applications of 7T MRI in Neuroimaging" at University Hospital.
July 16, 2025 at 12:59 PM
Reposted by Jonathan C. Lau
@cfmm.bsky.social speakers from @westernu.ca at the 7T Translational Alliance of North America meeting in Dallas, hosted by UTSW.
When in Texas…
July 14, 2025 at 12:52 AM
Reposted by Jonathan C. Lau
Honoured to give the keynote at the 7T Translational Alliance of North America meeting in Dallas this morning recognizing @cfmm.bsky.social leadership in 7T human imaging. We continue to be the only 🇨🇦 site at this meeting. @westernuresearch.bsky.social @westernu.ca
July 15, 2025 at 4:32 PM
Reposted by Jonathan C. Lau
Alert!!!!

“An Action Networks Model for Pain”

We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.

👉 thread below 🧵

osf.io/preprints/ps...
June 26, 2025 at 1:29 PM
Reposted by Jonathan C. Lau
Benchmarking methods for mapping functional connectivity in the brain | doi.org/10.1038/s415...

What is the best measure of functional connectivity (FC)?

led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
June 20, 2025 at 7:57 PM
Reposted by Jonathan C. Lau
Incredible story featuring #WIN Executive Committee member @jclauneuro.bsky.social - A Kitchener man is now seizure free following a rare epilepsy treatment at London Health Sciences Centre (LHSC) www.ctvnews.ca/london/artic...
A Kitchener man is now seizure free following a rare epilepsy treatment at London Health Sciences Centre (LHSC)
Neurosurgeon Dr. Jonathan Lau reviews medical scans with his patient Steven Kieffer, who underwent a rare epilepsy procedure called a laser ablation last year.
www.ctvnews.ca
June 6, 2025 at 1:12 PM
Reposted by Jonathan C. Lau
New paper in Imaging Neuroscience by Mohamad Abbass, Jonathan C. Lau, et al:

The impact of localization and registration accuracy on estimates of deep brain stimulation electrode position in stereotactic space

doi.org/10.1162/imag...
May 20, 2025 at 3:52 AM
Really proud of MohamadAbbass & team for pushing our preprint through to publication in @imagingneurosci.bsky.social! Hopefully the first of many in this journal. doi.org/10.1162/imag...

Appreciate all the supportive feedback about our AFIDs project during the review process.🧠🎯
The impact of localization and registration accuracy on estimates of deep brain stimulation electrode position in stereotactic space
Abstract. Effects of deep brain stimulation (DBS) depend on millimetric accuracy and are commonly studied across populations by registering patient scans to a stereotactic space. Multiple factors cont...
doi.org
May 24, 2025 at 5:07 PM
Reposted by Jonathan C. Lau
New paper in Imaging Neuroscience by Britta U. Westner, Tim M. Tierney, et al:

Cycling on the Freeway: The perilous state of open-source neuroscience software

doi.org/10.1162/imag...
May 7, 2025 at 7:25 AM
Reposted by Jonathan C. Lau
New paper in Imaging Neuroscience by Elodie Germani, Camille Maumet, et al:

On the validity of fMRI mega-analyses using data processed with different pipelines

doi.org/10.1162/imag...
May 1, 2025 at 2:42 PM
Reposted by Jonathan C. Lau
Amazing work through @hbhlmcgill.bsky.social from leading minds in neuroscience including @lisasaksida.bsky.social @mallarchak.bsky.social @maximoprado.bsky.social and Dr. Tom Durcan, also TRIDENT lead researchers! 🙌🌎🔬🐁
At #HBHLSymposium2025, experts from @mcgill.ca & @westernubrainscan.bsky.social shared their breakthroughs in non-invasive neurostimulation, iPSC models and circuit-based approaches for epilepsy, ALS & more, as part of the McGill-Western ITN. 🧠🔬 @borismontreal.bsky.social @jclauneuro.bsky.social
May 7, 2025 at 2:15 AM
Reposted by Jonathan C. Lau
At #HBHLSymposium2025, experts from @mcgill.ca & @westernubrainscan.bsky.social shared their breakthroughs in non-invasive neurostimulation, iPSC models and circuit-based approaches for epilepsy, ALS & more, as part of the McGill-Western ITN. 🧠🔬 @borismontreal.bsky.social @jclauneuro.bsky.social
May 6, 2025 at 7:12 PM
Reposted by Jonathan C. Lau
If you have an interest in non-human primate systems neuroscience and/or imaging esp. if it relates to development or learning, call me! These are major chair positions that come with at least $4M or $8M over 8 years, depending on career stage.
May 5, 2025 at 10:24 PM
Reposted by Jonathan C. Lau
Western University is seeking applications for Canada Excellence Research Chairs. Please reach out if you are interested in Theme 2: Neuroscience. Western has extraordinary strengths in cognitive, molecular and systems neuroscience across species (rodents, NHPs, humans) uwo.ca/research/cer...
May 5, 2025 at 10:47 PM
Reposted by Jonathan C. Lau
New: Energy use shapes brain organization and development. We use gene expression maps from the @alleninstitute.bsky.social Human Brain Atlas to map the main energy metabolism pathways in the brain. Led by @moohebatpe.bsky.social @misicbata.bsky.social @goliashf.bsky.social and Justine Hansen 🧵
March 18, 2025 at 9:48 PM
Reposted by Jonathan C. Lau
Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n
Homepage - openRxiv
openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.
openrxiv.org
March 11, 2025 at 1:20 PM
Reposted by Jonathan C. Lau
If you would like to postdoc in ultra high field MRI (3T+7T human, 9.4T+15.2T marmoset and mouse) in a well funded lab with tons of great neuroscience collaborations, drop me a DM soon.
Western Postdoctoral Fellowship Program
Western University, in vibrant London, Ontario, delivers an academic and student experience second to none.
uwo.ca
March 6, 2025 at 6:02 PM
Reposted by Jonathan C. Lau
I am excited to announce that I will be founding an institute for network stimulation at the University Hospital Cologne – already this coming May!
February 17, 2025 at 1:49 AM
Reposted by Jonathan C. Lau
🎉 Lyle Muller, Laura Batterink, and @jclauneuro.bsky.social awarded CIHR funding to study neural traveling waves in sleep spindles as a biological mechanism for memory consolidation. Dreaming big for understanding human memory! 🧠💭 #SleepScience #MemoryConsolidation #CIHR
February 6, 2025 at 3:17 PM
Reposted by Jonathan C. Lau
Hope you'll forgive a quick thread as I take over as the new EiC of @elife.bsky.social
January 30, 2025 at 4:05 PM
Reposted by Jonathan C. Lau
our NIH HEAL initiative funded biomarkers study now out @jama.com JAMA Neurology

open access, open data and code

w/ @drsmschabrun.bsky.social

jamanetwork.com/journals/jam...
Predicting Individual Pain Sensitivity Using a Novel Cortical Biomarker Signature
This cohort study analyzes electroencephalography data from healthy participants to analyze and validate a cortical biomarker signature for pain, which comprised the measures sensorimotor peak alpha f...
jamanetwork.com
January 27, 2025 at 4:43 PM
Reposted by Jonathan C. Lau
Out in @natureneuro.bsky.social today 🥂

Cytoarchitecture, wiring and signal flow of the human default mode network

Combining 3D histology, 7T MRI, and connectomics to explore DMN structure-function associations

Led by Casey Paquola, @themindwanders.bsky.social & a terrific team of colleagues 🙏
The architecture of the human default mode network explored through cytoarchitecture, wiring and signal flow - Nature Neuroscience
The default mode network (DMN) is implicated in cognition and behavior. Here, the authors show that the DMN is cytoarchitecturally heterogeneous, it contains regions receptive to input from the sensory cortex and a core relatively insulated from environmental input, and it uniquely balances its output across sensory hierarchies.
www.nature.com
January 28, 2025 at 2:24 PM