TRIDENT Preclinical Trials
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tridentpct.bsky.social
TRIDENT Preclinical Trials
@tridentpct.bsky.social
Multi-site, transformative preclinical evaluation of novel neurotherapeutics through a Government of Canada $24M New Frontiers In Research grant. Check out our website tridentpreclinicaltrials.org for more info or email info@tridentpreclinicaltrial.org!
Pinned
The TRIDENT proof-of-concept platform began in 2023 through the incredible support of a $24M grant from the Government of Canada's New Frontiers In Research Fund- Transformation stream.
Check out our website tridentpreclinicaltrials.org or the video below 👇 #NFRF
www.youtube.com/watch?v=RCr3...
Fight against neurodegenerative diseases - NFRF
YouTube video by Western University
www.youtube.com
Hard to believe last week we were all together for the #TRIDENT 2025 Annual General Meeting...a yearly cross-site event uniting all members of the TRIDENT platform in 2 days of collaborative discussions and discovery! Part 1 recap just dropped below! #NFRF 👇🌎🎉🎤🤝tridentpreclinicaltrials.org
November 13, 2025 at 4:58 PM
Reposted by TRIDENT Preclinical Trials
Each year, we come together to honour all who have served our country in times of war, conflict, and peace. #WesternU has been associated with Canada's armed forces throughout our shared history, and many of our members serve in the Canadian Armed Forces.
#LestWeForget #LdnOnt
November 11, 2025 at 12:02 PM
Absolutely amazing work @mind-western.bsky.social... a true imaging treat to look at this #fluorescencefriday!
Slick-H/M83 mice injected with alpha synuclein preformed fibrils. Magenta pS129 and yellow for eGFP driven by the Thy-1 promoter. blue nuclei #fluorescencefriday courtesy of Vlad Novikov. Shaz and Nadia from the @mind-western.bsky.social
November 7, 2025 at 9:57 PM
Yay Amr! Please check out the below talk from one of our #TRIDENT Highly Qualified Personnel!!! 😍👇🎙
Meet our second and final speaker 🗣️ Amr will be presenting at TOMORROW’S webinar! You can register here: tinyurl.com/4a45v6mu
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And remember, you can stay up to date on webinars, events, and more by subscribing to our mailing list: t.co/Oa9dLowy1h

@canacn.bsky.social
November 5, 2025 at 5:37 PM
Ending the #TRIDENT 2025 Annual General Meeting by looking to the future of #openscience with @richardgold.bsky.social! #NFRF 🤩🌎🔬🤝
November 5, 2025 at 12:15 AM
'Twas the night of the #TRIDENT 2025 Annual General Meeting and I see one amazing world-class group of interdisciplinary collaborators! 👀🌎🔬🎤🤩 Thank you to the Ivey Donald K. Johnson Center for hosting such an incredible event!
November 3, 2025 at 10:27 PM
So excited to have you be a part of this event! 🥳 🌎🔬#NFRF
Great to be in Toronto for the Second AG meeting for @tridentpct.bsky.social where our 🐁 molecular and cognition core will show what we are up to in the last 2 years facilitated by @touchscreencog.bsky.social and we will continue to learn about our organoid and marmoset models.
November 3, 2025 at 2:15 PM
I see the face!!!!! 😱 😬 🧠 🎃 #FluorescenceFriday imaging from the Lightsheet Microscopy team at Western.
and another 👻 entry for #fluorescencefriday courtesy of Nadia Haghbin and Shaz
October 31, 2025 at 2:00 PM
Stranger Things happening in the lab this #fluorescencefriday! 🔬🧠🙃🎃👻😱
👻 #fluorescencefriday weird microglia (yellow) in a model of synucleinopathy courtesy Anoosha Attaran
October 31, 2025 at 1:18 PM
Sneak peak of one of the pix from our lightsheet microscopy lab tour at Western....seriously cool stuff! 🧠 🔬 😍
Is it candy? Nope, it is a spooky 👻 cleared mouse 🧠 used for #fluorescencefriday movies
October 30, 2025 at 11:57 PM
Counting down the days until our annual event on MONDAY that brings together team members and stakeholders across the entire #TRIDENT platform for two action-packed days of collaboration, knowledge sharing, and discovery! 🌎🎤🔬🎉👇#openscience #neuroscience #braindisease tridentpreclinicaltrials.org
October 30, 2025 at 1:22 PM
Health Canada has authorized LEQEMBI® (lecanemab) for the treatment of early Alzheimer’s disease. Lecanemab serves as a comparative control in #TRIDENT’s preclinical validation studies.

globalnews-ca.cdn.ampproject.org/c/s/globalne...
Health Matters: New drug slows down Alzheimer’s decline | Watch News Videos Online
globalnews-ca.cdn.ampproject.org
October 29, 2025 at 10:29 PM
Check out this upcoming event below, involving amazing women researchers including @lisasaksida.bsky.social and @liisagalea.bsky.social, also TRIDENT leads! 👇🌎🎤🤩
You're Invited! Join us on Nov. 27 for an insightful conversation about SGBA+ in brain research at @westernu.ca moderated by @lisasaksida.bsky.social. Register here: www.eventbrite.ca/e/brainscan-...
October 29, 2025 at 10:22 PM
Awesome spotlight on sex and aging featuring some incredible voices like @liisagalea.bsky.social, also TRIDENT Sex-Based Analysis+ lead researcher! 🤩 🌎 🎙👇
www.dementiaresearcher.nihr.ac.uk/xxplored-pod...
XXplored Podcast – Why Sex Matters & What we’ve Ignored in Brain Ageing - DEMENTIA RESEARCHER
Why do sex & gender matter in brain ageing? In XXplored, Dr Laura Stankeviciute talks women’s brain health with Prof Liisa Galea & Dr Maria Teresa Ferretti.
www.dementiaresearcher.nihr.ac.uk
October 29, 2025 at 10:20 PM
Science, synergy, and maybe a few selfies...can’t wait to see our Douglas Research Centre colleagues in a few days at the #TRIDENT 2025 Annual General Meeting 📸🧠 😍. Check out more about their world-class research facility via the link, below! 🔬 🌍 🔬

douglas.research.mcgill.ca
Home - The Douglas Research Centre
Upcoming Events View full calendar Recent news More news Learn more about the Douglas Research Centre Recent videos View more videos on our YouTube Channel
douglas.research.mcgill.ca
October 29, 2025 at 4:22 PM
Hard to believe we are 1 WEEK away from the 2025 #TRIDENT Annual General Meeting! Check out the recap below from last year, an incredible 2 day event bringing together all of our platform team members, leadership and key external stakeholder representatives! #NFRF #neuroscience #collaboration 🌍👏👇
October 27, 2025 at 7:09 PM
Friday's Forecast: 100% chance of Fluorescence 🌈🔬🧠....great job team!!!! #fluorescencefriday
#fluorescencefriday Side by side comparison of alpha synuclein S129 (magenta), a marker of #parkinson’s , in M83 hemyzigous mice injected with human pre formed fibrils @shahrzadbahrampour.bsky.social Vlad Novikov clearing with SHIELD @lifecanvastech.bsky.social imaged at MIND platform @westernu.ca
October 24, 2025 at 5:26 PM
Multi-site means moving our Annual General Meeting around our academic partnering institutions each year to maximize an accessible, collaborative event. We are so excited to highlight our Toronto teams, including the Joel Watts Lab; see more below! 🤩🐀🔬🎉👇
Did you know TRIDENT uses advanced humanized mouse models to study & develop treatments for brain disease at multiple leading Canadian research labs? Check out this reel showcasing the site at the U of T Joel Watts Lab! 👇 🔬 🐁 #TRIDENT #NFRF #neuroscience #brain tridentpreclinicaltrials.org
October 22, 2025 at 12:22 PM
We are looking forward to welcoming our esteemed project colleagues, led by @tedfon.bsky.social and Dr. Tom Durcan at @theneuro.bsky.social EDDU (Early Drug Discovery Unit) as part of our Annual General Meeting in 2 weeks! Check out the spotlight on this amazing team, below! 👇 🔬
youtu.be/z5u3WWVOQoQ
"A Local Platform with a Global Outreach": A talk with the Neuro's EDDU's Director, Tom Durcan
YouTube video by MontrealNeuro
youtu.be
October 20, 2025 at 4:02 PM
We are so honoured to sponsor the @mjfoxfoundation.bsky.social at the PDTC event. What an incredible opportunity for outreach to a group aligned in advancing a cure for Parkinson's Disease. #TRIDENT 🤩🌍🔬🙏
@tridentpct.bsky.social is thrilled to be here in NYC as a sponsor at the Michael J. Fox Parkinson’s Disease Therapeutics Conference.
October 16, 2025 at 12:59 PM
We see a #TRIDENT spotight in the CIHR Faces of Health Research storybook, among other stories about the life-changing research happening right here in Canada! #NFRF #impact #neuroscience. Check it out, below! 🇨🇦🔬🌍🤩👀👇 cihr-irsc.gc.ca/e/54163.html
Celebrating Health Research: The faces of health research 2025 - CIHR
cihr-irsc.gc.ca
October 16, 2025 at 12:38 PM
Had a great time at the @mind-western.bsky.social Lightsheet Meeting Series this week, an amazing, interactive talk led by Christopher Pfeiffer-Kelly of LifeCanvas Technologies Inc. @braincanada.bsky.social @maximoprado.bsky.social🔬🖥️🤩
October 15, 2025 at 1:55 PM
Check out this faculty spotlight on Dr. Justine Clery, an Assistant Professor at the Dept of Neurology and Neurosurgery at McGill University, also a #TRIDENT Marmoset lead. An insightful, poignant interview with an incredible Early Career Researcher! #NFRF YouTube link here: youtu.be/_o_QfpIs3d0
Dr. Justine Clery Faculty Spotlight
YouTube video by TRIDENT Preclinical Trials
youtu.be
October 14, 2025 at 5:57 PM
Reposted by TRIDENT Preclinical Trials
Joel Mokyr's work points to the transformational impact of #OpenScience. When we open up knowledge and share it more, we accelerate the potential of people to create new, practical ideas that lead to growth. @conscience-network.bsky.social @tridentpct.bsky.social
October 13, 2025 at 3:49 PM
We are grateful for the hard work of all our team members, to all our project stakeholders groups including patients and families with lived experience, and especially our #NFRF support as without it this world-class, revolutionary research would not be possible! tridentpreclinicaltrials.org
October 13, 2025 at 2:48 PM