LifeCanvas Technologies
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lifecanvastech.bsky.social
LifeCanvas Technologies
@lifecanvastech.bsky.social
Pioneering end-to-end solutions for 3D spatial biology.
www.lifecanvastech.com
Reposted by LifeCanvas Technologies
Lab is thrilled to leave frigid NY to go to sunny San Diego for #SfN2025 😂

Mon AM posters:
LBP182 - Psilocybin and layer 1 interneurons
LBP183 - Psilocybin in chronic stress model
LBP184 - Drugs + snRNAseq

Tue PM posters:
LL18 - Psilocybin and pyramidal cell types
MM3 - Drugs + rabies tracing
November 13, 2025 at 9:33 PM
Save room in your #SfN25 itinerary for some more 3D 🧠 data exploring research areas from brain development to neuroimmune pathways! Next week's poster lineup features presentations from Drs. @ingvildeb.bsky.social, Élora Midavaine, Quan Jiang, Zhen Wang, & Yidan Chen.
November 13, 2025 at 2:44 PM
Reposted by LifeCanvas Technologies
Excited to share insights of spinal circuit architecture at #SfN25! Big thanks to the @lifecanvastech.bsky.social team—Chris Tsang, Leah Chesnut, Brenna Fearey, and Zachary Woods—and the VCU Imaging Core's Dr. Tytus Bernas and Terry Smith for their excellent technical support. 🔬
#Neuroscience #SfN
November 13, 2025 at 4:36 AM
This weekend kicks off #SfN25! Have you made your poster game plan yet?

Today and tomorrow we'll be sharing a selection of posters featuring LifeCanvas 3D histology and imaging data 🧠 that you can add to your agenda. Check out our Sunday schedule below.
November 12, 2025 at 3:08 PM
In a new Nature study, Dr. @gabineiman.bsky.social et al. developed an in vitro screening method to predict transfection efficacy of LNP-mRNA complexes in the heart, validating it with #SmartSPIM imaging in whole mouse hearts. Check out the paper: bit.ly/444P0rT

@qb3-berkeley.bsky.social
November 11, 2025 at 5:50 PM
That's not discount Halloween candy on the right – it's a cleared mouse brain! We recently went down to New Orleans to visit @tulaneu.bsky.social's Brain Institute and demonstrate #tissueclearing techniques for neuroscientists. Thanks Dr. Deniz Ucar for hosting us at the Cell & Tissue Imaging Core!
November 10, 2025 at 3:42 PM
Incredibly exciting to see our tissue clearing and #SmartSPIM imaging tech in some of these groundbreaking studies!
The developing brain? Yeah, we have it covered.

The first brain cell atlas of the developing mammalian brain is now available to curious minds and researchers everywhere.

Check out the findings in @nature.com: www.nature.com/collections/...

🎨 Cover art by Jasiek Krzysztofiak
November 7, 2025 at 9:51 PM
📣📣 We've extended our travel award deadline to Tues, Nov 11th. A few more days left to apply for $1000 towards #SfN25 travel expenses! Just tell us how you used LifeCanvas tech in your poster. Winner announced next Friday, 11/14!
November 7, 2025 at 7:15 PM
Glomeruli, the filtering parts of nephrons, are visible in cyan in this mouse kidney section imaged with DALISPIM. In mice, kidneys have over 10,000 nephrons!

Our new open-top #lightsheet microscope's unique design allowed us to image this 1-mm thick sample directly in a 12-well plate.
November 7, 2025 at 3:57 PM
"I have too many cool 3D microscopy images in my algorithm" - no one

Connect with us on LinkedIn and Instagram to bring some ✨fluorescence✨ into your daily scroll:

LI: www.linkedin.com/company/life...
IG: instagram.com/lifecanvas_tec
November 6, 2025 at 3:36 PM
Dr. Khalil Ramadi's lab at NYU Abu Dhabi used the LifeCanvas pipeline to develop CORAL, an ingestible device to non-invasively sample the small intestine #microbiome. The #SmartSPIM video below shows blood vessels (pink) & epithelial cells (blue) in rat duodenum. Check out the paper: bit.ly/3JncRfA
November 5, 2025 at 3:56 PM
Congratulations! 🥂
Deeply honored to receive this year's Tianqiao and Chrissy Chen Young Investigator Award from @sfn.org Grateful to all lab members and my mentors.
Congratulations to the 2025 SfN award & prize recipients!

Their dedication to advancing the understanding of the brain paves the way for future discoveries.

SfN looks forward to celebrating their achievements at #SfN25.

Learn about the recipients.

🔗 vist.ly/4cni8

#neurosky
November 3, 2025 at 10:07 PM
The days are getting darker, so we're celebrating what we can do with light 💡 Come hang with us at the New England Society for Microscopy's Fall Symposium at @brandeisuniversity.bsky.social this Thurs & Fri. We'll be ready to talk all things light-sheet #microscopy!

@nesmicroscopy.bsky.social
November 3, 2025 at 6:29 PM
Forbidden gummy 🎃
Is it candy? Nope, it is a spooky 👻 cleared mouse 🧠 used for #fluorescencefriday movies
October 31, 2025 at 7:45 PM
1 week left to apply for our SfN Travel Award! It's easy to enter: just tag us & tell us about your poster. The award is open to anyone who used LifeCanvas tools for their #SfN2025 poster. We love seeing all the innovative ways scientists use our tech to explore #neurobiology 🧠
October 31, 2025 at 4:00 PM
At first, these may look like individually mounted samples. But all 12 datasets were captured at once, directly in a 12-well plate, using our new open-top #DALISPIM light sheet microscope.🔬

Vasculature (CD31) in magenta, parvalbumin cells (endogenous tdTomato) in yellow, and nuclei (DAPI) in cyan.
October 30, 2025 at 4:16 PM
Reposted by LifeCanvas Technologies
Tomorrow! Come join us for MicRoN’s Open House Symposium. Learn about the research we get to support, meet our staff and instruments.

micron.hms.harvard.edu/micron-open-...
MicRoN Open House & Symposium 2025
Please join MicRoN at celebrating our trainees in Oct 29th 2025, 12:45-6:30 pm VSC1031 for our Open House Symposium. Discover how MicRoN can support your image-based research, meet our trainees and co...
micron.hms.harvard.edu
October 28, 2025 at 5:25 PM
Why are half of people with Down syndrome born with heart defects?

That’s what @sanjeevranade.bsky.social & Feiya Li et al. uncovered in a new study using single-cell #transcriptomics, CROP-Seq, #SmartSPIM imaging to characterize the genetic basis of trisomy 21-induced effects on heart development.
Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21 - Nature
Studies using human pluripotent stem cells and a mouse model of Down syndrome identify HMGN1 as a key contributor to congenital heart defects in individuals with Down syndrome.
www.nature.com
October 29, 2025 at 2:33 PM
We are excited to launch DALISPIM, our new open-top light sheet microscope. 📣 🎉 DALISPIM packs high-res, high-speed imaging into an inverted configuration uniquely suited for automation & large-scale sample screening. Stay tuned to see brand new data!

Learn more: lifecanvastech.com/products/dal...
October 28, 2025 at 1:29 PM
Reposted by LifeCanvas Technologies
#fluorescencefriday Side by side comparison of alpha synuclein S129 (magenta), a marker of #parkinson’s , in M83 hemyzigous mice injected with human pre formed fibrils @shahrzadbahrampour.bsky.social Vlad Novikov clearing with SHIELD @lifecanvastech.bsky.social imaged at MIND platform @westernu.ca
October 24, 2025 at 4:56 PM
Earlier this month, we hosted a #tissueclearing workshop at UMN's University Imaging Centers @umnuic.bsky.social. We had a great time walking through the SmartBatch+ workflow with neuroscience researchers. Thanks Laurel Schuck and Mark Sanders for your expertise and support!
October 24, 2025 at 3:02 PM
Hello scientists of Bluesky! Since we're new here, what better way to introduce ourselves than to share our collection of light-sheet #microscopy data, featuring a diverse range of species and tissue types 🐠🐁🦎🔬: vimeo.com/lifecanvastech

Stay tuned for more #bioimaging data drops coming soon!
October 22, 2025 at 1:43 PM