Jonathan Barra, Ph.D.
@jbarra.bsky.social
Post-doc at Mount Sinai (Bravo-Cordero Lab)| Previously post-doc at Margarida Barroso Lab (Albany Medical College, NY) | Ph.D. Medical Sciences PUC, Chile (At Alfonso González Lab) | Studying Metastasis Cell Biology
Reposted by Jonathan Barra, Ph.D.
new out in Nature, very cool story www.nature.com/articles/s41...
Activation of lysosomal iron triggers ferroptosis in cancer - Nature
Some cancer cells exhibit high loads of reactive iron in lysosomes, and this feature is exploited by using fentomycin-1, a newly developed small molecule, to induce ferroptosis.
www.nature.com
May 7, 2025 at 3:48 PM
new out in Nature, very cool story www.nature.com/articles/s41...
Reposted by Jonathan Barra, Ph.D.
We are proud of our small part supporting a diversified, equitable, and inclusive new generation of scientists. We will not change.
2025 HCS Capstone Grant Applications are NOW OPEN!
To learn more and to apply, click here: hcs.memberclicks.net/capstone-gra...
Deadline: April 15, 2025
#scicomm #AcademicChatter #STEMeducation
To learn more and to apply, click here: hcs.memberclicks.net/capstone-gra...
Deadline: April 15, 2025
#scicomm #AcademicChatter #STEMeducation
March 19, 2025 at 11:13 AM
We are proud of our small part supporting a diversified, equitable, and inclusive new generation of scientists. We will not change.
Reposted by Jonathan Barra, Ph.D.
born too late to get a two Western blot Nature paper, born too early to be a science TikTokker, born just in time to start a postdoc during a global pandemic and look for faculty positions during a historic hiring freeze
March 10, 2025 at 4:32 PM
born too late to get a two Western blot Nature paper, born too early to be a science TikTokker, born just in time to start a postdoc during a global pandemic and look for faculty positions during a historic hiring freeze
Reposted by Jonathan Barra, Ph.D.
We’re Standing Up for Science – because science is for everyone. Thank you Rep Paul Tonko @reppaultonko.bsky.social for joining us at the NY State Capitol at Albany!
#standupforscience2025 ・ #sciencenotsilence ・ #scienceforall #AcademicSky #science #ScienceSky 🧪
#standupforscience2025 ・ #sciencenotsilence ・ #scienceforall #AcademicSky #science #ScienceSky 🧪
March 1, 2025 at 7:31 PM
We’re Standing Up for Science – because science is for everyone. Thank you Rep Paul Tonko @reppaultonko.bsky.social for joining us at the NY State Capitol at Albany!
#standupforscience2025 ・ #sciencenotsilence ・ #scienceforall #AcademicSky #science #ScienceSky 🧪
#standupforscience2025 ・ #sciencenotsilence ・ #scienceforall #AcademicSky #science #ScienceSky 🧪
Reposted by Jonathan Barra, Ph.D.
From the NYT: The Devastating Legacy of Lies in Alzheimer’s Science
Opinion | The Devastating Legacy of Lies in Alzheimer’s Science
Fraud in research needs to end.
www.nytimes.com
January 26, 2025 at 6:33 PM
From the NYT: The Devastating Legacy of Lies in Alzheimer’s Science
Reposted by Jonathan Barra, Ph.D.
Great lunch of the Multiphoton microscopy conference speakers at SPIE Photonics West! @digmanlab.bsky.social and many others!
January 27, 2025 at 4:39 AM
Great lunch of the Multiphoton microscopy conference speakers at SPIE Photonics West! @digmanlab.bsky.social and many others!
Reposted by Jonathan Barra, Ph.D.
Very excited to tell you about a great review on "Modeling intratumor heterogeneity in breast cancer" published in Biofabrication. This was mainly the work of Liz McDonough with David Corr, RPI BME, in collaboration with Fiona Ginty from GE research labs and yours truly. doi.org/10.1088/1758...
December 7, 2024 at 8:08 PM
Very excited to tell you about a great review on "Modeling intratumor heterogeneity in breast cancer" published in Biofabrication. This was mainly the work of Liz McDonough with David Corr, RPI BME, in collaboration with Fiona Ginty from GE research labs and yours truly. doi.org/10.1088/1758...
Reposted by Jonathan Barra, Ph.D.
Today @gabbyfredman.bsky.social and Albany Med welcomed Dr Serhan, from Brigham and Women’s Hospital and Harvard Medical School, serhanlab.bwh.harvard.edu, for an outstanding talk on the lipid mediators and mechanisms in inflammation resolution. Exciting research and wonderful clear presentation!
December 6, 2024 at 2:47 AM
Today @gabbyfredman.bsky.social and Albany Med welcomed Dr Serhan, from Brigham and Women’s Hospital and Harvard Medical School, serhanlab.bwh.harvard.edu, for an outstanding talk on the lipid mediators and mechanisms in inflammation resolution. Exciting research and wonderful clear presentation!
Reposted by Jonathan Barra, Ph.D.
The introduction of glutaraldehyde as #fixative by Sabatini in 1963, a real revolution for biological #electromicroscopy. Looking through the old literature, the improvement (since 1963) compared to the previously used osmium tetroxide as primary fixative is incredible. doi.org/10.1083/jcb....
CYTOCHEMISTRY AND ELECTRON MICROSCOPY | Journal of Cell Biology | Rockefeller University Press
doi.org
December 4, 2024 at 8:01 AM
The introduction of glutaraldehyde as #fixative by Sabatini in 1963, a real revolution for biological #electromicroscopy. Looking through the old literature, the improvement (since 1963) compared to the previously used osmium tetroxide as primary fixative is incredible. doi.org/10.1083/jcb....
November 28, 2024 at 2:23 AM
Reposted by Jonathan Barra, Ph.D.
If only there was some way to remove viruses from milk www.nbcnews.com/news/amp/rcn...
Bird flu detected in raw milk sold in California, health officials say
California health officials warned the public to avoid drinking one batch of whole raw milk from Raw Farm, which has issued a voluntary recall.
www.nbcnews.com
November 27, 2024 at 3:03 AM
If only there was some way to remove viruses from milk www.nbcnews.com/news/amp/rcn...
Reposted by Jonathan Barra, Ph.D.
Exciting day on Bluesky for @biologists.bsky.social, although somehow setting up the @jcellsci.bsky.social and @focalplane.bsky.social accounts felt quite exhausting. Glad that I now get to go for drinks with the hugging group from St Johnston lab past and present!
a group of sea creatures including an octopus turtle and a fish
Alt: a group of sea creatures including an octopus turtle and a fish
media.tenor.com
November 25, 2024 at 4:33 PM
Exciting day on Bluesky for @biologists.bsky.social, although somehow setting up the @jcellsci.bsky.social and @focalplane.bsky.social accounts felt quite exhausting. Glad that I now get to go for drinks with the hugging group from St Johnston lab past and present!
Reposted by Jonathan Barra, Ph.D.
Excited to share our latest findings on how the phosphoinositide PI4P pool at the trans-Golgi network (TGN) is regulated through a SYS1-ARFRP1-ARL5-ARMH3-PI4KB pathway, in which ARMH3 (also known as C10orf76) acts as an ARL5 effector to activate PI4KB. rdcu.be/d1dZ2
November 23, 2024 at 1:32 PM
Excited to share our latest findings on how the phosphoinositide PI4P pool at the trans-Golgi network (TGN) is regulated through a SYS1-ARFRP1-ARL5-ARMH3-PI4KB pathway, in which ARMH3 (also known as C10orf76) acts as an ARL5 effector to activate PI4KB. rdcu.be/d1dZ2
Reposted by Jonathan Barra, Ph.D.
1st post on bluesky! I might as well use this opportunity to plug our recent preprint where we identify a potential neurophysiological mechanism driving aberrant HPA-axis activity in breast cancer.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A brain-body feedback loop driving HPA-axis dysfunction in breast cancer
Breast cancer patients often exhibit disrupted circadian rhythms in circulating glucocorticoids (GCs), such as cortisol. This disruption correlates with reduced quality of life and higher cancer morta...
www.biorxiv.org
November 22, 2024 at 9:38 PM
1st post on bluesky! I might as well use this opportunity to plug our recent preprint where we identify a potential neurophysiological mechanism driving aberrant HPA-axis activity in breast cancer.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Jonathan Barra, Ph.D.
Interesting paper showing that yeast adaptor protein complex AP-3 lacks "ear" domains, and that the disordered "hinge" domains are required for budding from the late Golgi (equivalent to the mammalian TGN) journals.biologists.com/jcs/article/...
November 21, 2024 at 6:22 PM
Interesting paper showing that yeast adaptor protein complex AP-3 lacks "ear" domains, and that the disordered "hinge" domains are required for budding from the late Golgi (equivalent to the mammalian TGN) journals.biologists.com/jcs/article/...