InterPro
@interprodb.bsky.social
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.
ebi.ac.uk/interpro/
ebi.ac.uk/interpro/
Pinned
🚀InterPro 107.0 is live!
✨Updated to Pfam 38.0
✨1,068 new InterPro entries
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk
✨Updated to Pfam 38.0
✨1,068 new InterPro entries
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk
🚀InterPro 107.0 is live!
✨Updated to Pfam 38.0
✨1,068 new InterPro entries
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk
✨Updated to Pfam 38.0
✨1,068 new InterPro entries
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk
October 23, 2025 at 12:27 PM
🚀InterPro 107.0 is live!
✨Updated to Pfam 38.0
✨1,068 new InterPro entries
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk
✨Updated to Pfam 38.0
✨1,068 new InterPro entries
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk
Quinoa thrives at 4,000m altitude where many crops struggle. Heat Shock Proteins helps protect plant cells from environmental stress. These molecular mechanisms in traditional crops may inform climate-resilient agriculture strategies. 💻🧪
More info: proteinswebteam.github.io/interpro-blo...
More info: proteinswebteam.github.io/interpro-blo...
October 2, 2025 at 2:59 PM
Quinoa thrives at 4,000m altitude where many crops struggle. Heat Shock Proteins helps protect plant cells from environmental stress. These molecular mechanisms in traditional crops may inform climate-resilient agriculture strategies. 💻🧪
More info: proteinswebteam.github.io/interpro-blo...
More info: proteinswebteam.github.io/interpro-blo...
Interested in studying Parkinson's disease? Have a look at our blog post below
🧬🧪💻 New blog post: Diving deep into the key proteins behind Parkinson's disease. From α-synuclein to LRRK2, we're unravelling the molecular mysteries that could hold the key to treatment breakthroughs. Read more: proteinswebteam.github.io/interpro-blo... #Parkinsons #Neuroscience
September 17, 2025 at 10:24 AM
Interested in studying Parkinson's disease? Have a look at our blog post below
Reposted by InterPro
📢 Happy to announce that Ensembl 115 and Ensembl Genomes 62 are out! This release features ~120000 new protein coding transcripts in human GRCh38, 2 new cattle, 7 new plants and 20 new metazoa! 🧬🐮 🫛🪲
Read more here ➡️ zurl.co/poyXM
Read more here ➡️ zurl.co/poyXM
Ensembl 115 has been released! – Ensembl Blog
zurl.co
September 2, 2025 at 7:54 PM
📢 Happy to announce that Ensembl 115 and Ensembl Genomes 62 are out! This release features ~120000 new protein coding transcripts in human GRCh38, 2 new cattle, 7 new plants and 20 new metazoa! 🧬🐮 🫛🪲
Read more here ➡️ zurl.co/poyXM
Read more here ➡️ zurl.co/poyXM
Feature Spotlight: Taxonomy Sunburst
Discover the taxonomic breadth of your InterPro entry at a glance with our dynamic sunburst chart! 🕸️ 💻🧪🧬
Discover the taxonomic breadth of your InterPro entry at a glance with our dynamic sunburst chart! 🕸️ 💻🧪🧬
August 27, 2025 at 3:55 PM
Feature Spotlight: Taxonomy Sunburst
Discover the taxonomic breadth of your InterPro entry at a glance with our dynamic sunburst chart! 🕸️ 💻🧪🧬
Discover the taxonomic breadth of your InterPro entry at a glance with our dynamic sunburst chart! 🕸️ 💻🧪🧬
InterProScan 6 (beta) is here 🎉
A Nextflow-powered, containerised overhaul for scalable, reproducible protein annotation—decoupled software/data, automated data handling, and smoother runs across HPC and cloud.
Feedback welcome!
github.com/ebi-pf-team/...
💻🧪🧬
A Nextflow-powered, containerised overhaul for scalable, reproducible protein annotation—decoupled software/data, automated data handling, and smoother runs across HPC and cloud.
Feedback welcome!
github.com/ebi-pf-team/...
💻🧪🧬
August 8, 2025 at 9:32 AM
InterProScan 6 (beta) is here 🎉
A Nextflow-powered, containerised overhaul for scalable, reproducible protein annotation—decoupled software/data, automated data handling, and smoother runs across HPC and cloud.
Feedback welcome!
github.com/ebi-pf-team/...
💻🧪🧬
A Nextflow-powered, containerised overhaul for scalable, reproducible protein annotation—decoupled software/data, automated data handling, and smoother runs across HPC and cloud.
Feedback welcome!
github.com/ebi-pf-team/...
💻🧪🧬
🧬 The InterPro/Pfam team will be presenting at #ISMB2025 next week in Liverpool!
🎤 Multiple talks & 📊 posters on protein analysis & classification
💻🧪
🎤 Multiple talks & 📊 posters on protein analysis & classification
💻🧪
July 18, 2025 at 2:11 PM
🧬 The InterPro/Pfam team will be presenting at #ISMB2025 next week in Liverpool!
🎤 Multiple talks & 📊 posters on protein analysis & classification
💻🧪
🎤 Multiple talks & 📊 posters on protein analysis & classification
💻🧪
🧬 The InterPro/Pfam team will be presenting at #ISMB2025 next week in Liverpool!
Join us July 20-24 at the world's largest #bioinformatics conference!
#ISMBECCB2025 #ProteinAnalysis #ComputationalBiology
💻🧪
Join us July 20-24 at the world's largest #bioinformatics conference!
#ISMBECCB2025 #ProteinAnalysis #ComputationalBiology
💻🧪
July 18, 2025 at 2:09 PM
🧬 The InterPro/Pfam team will be presenting at #ISMB2025 next week in Liverpool!
Join us July 20-24 at the world's largest #bioinformatics conference!
#ISMBECCB2025 #ProteinAnalysis #ComputationalBiology
💻🧪
Join us July 20-24 at the world's largest #bioinformatics conference!
#ISMBECCB2025 #ProteinAnalysis #ComputationalBiology
💻🧪
🧬✨ Excited to present at @jobim2025.bsky.social this week in Bordeaux!
🎤 Talk 08/07 16:50, amphi E: Pfam: embracing AI/ML by @typhainepl.bsky.social
📊 Poster #97: InterPro: Accelerating Protein Annotation with AI by @matthiasblum.bsky.social
💻🧪
🎤 Talk 08/07 16:50, amphi E: Pfam: embracing AI/ML by @typhainepl.bsky.social
📊 Poster #97: InterPro: Accelerating Protein Annotation with AI by @matthiasblum.bsky.social
💻🧪
July 7, 2025 at 8:21 AM
🧬✨ Excited to present at @jobim2025.bsky.social this week in Bordeaux!
🎤 Talk 08/07 16:50, amphi E: Pfam: embracing AI/ML by @typhainepl.bsky.social
📊 Poster #97: InterPro: Accelerating Protein Annotation with AI by @matthiasblum.bsky.social
💻🧪
🎤 Talk 08/07 16:50, amphi E: Pfam: embracing AI/ML by @typhainepl.bsky.social
📊 Poster #97: InterPro: Accelerating Protein Annotation with AI by @matthiasblum.bsky.social
💻🧪
Reposted by InterPro
Level up your protein prediction skills with the updated EMBL-EBI Training AlphaFold practical course.
Now featuring #AlphaFold Server and AlphaFold 3. Start your training today: www.ebi.ac.uk/training/onl...
AlphaFold, developed by @ebi.embl.org and Google DeepMind.
Now featuring #AlphaFold Server and AlphaFold 3. Start your training today: www.ebi.ac.uk/training/onl...
AlphaFold, developed by @ebi.embl.org and Google DeepMind.
June 26, 2025 at 8:36 AM
Level up your protein prediction skills with the updated EMBL-EBI Training AlphaFold practical course.
Now featuring #AlphaFold Server and AlphaFold 3. Start your training today: www.ebi.ac.uk/training/onl...
AlphaFold, developed by @ebi.embl.org and Google DeepMind.
Now featuring #AlphaFold Server and AlphaFold 3. Start your training today: www.ebi.ac.uk/training/onl...
AlphaFold, developed by @ebi.embl.org and Google DeepMind.
Does taste depend on our genes? Discover how variations in taste receptors—from TAS2Rs that gate bitterness to olfactory genes that make cilantro taste soapy—and even pain receptors for spice shape what we love (and hate) on our plates. Read more: proteinswebteam.github.io/interpro-blo... 💻🧪👅🧬
![Schematic diagram showing taste signal transmission between the tongue (with taste buds that contain taste cells harbouring GPCRs) and brain. Taste GPCRs are activated by specific food compounds, recruit specific G proteins that further induce intracellular calcium release. Adapted from [https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28:_Biosignaling_-_Capstone_Volume_I/28.18:_Signal_Transduction_-_Taste_(Gustation)].](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:2b2g3csqntyhbjba6zutidvo/bafkreiarei32po5buevs63s7abazj42rdvx5w7pnszlg2zduhyqlpfqxdu@jpeg)
June 26, 2025 at 9:44 AM
Does taste depend on our genes? Discover how variations in taste receptors—from TAS2Rs that gate bitterness to olfactory genes that make cilantro taste soapy—and even pain receptors for spice shape what we love (and hate) on our plates. Read more: proteinswebteam.github.io/interpro-blo... 💻🧪👅🧬
🚀 InterPro 106.0 is now live!
✨ Updated to Pfam 37.4
✨ 683 new entries added
✨ Enhanced protein classification coverage
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk 💻🧪🧬
#Bioinformatics #ProteinScience #Pfam #EMBLEBI
✨ Updated to Pfam 37.4
✨ 683 new entries added
✨ Enhanced protein classification coverage
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk 💻🧪🧬
#Bioinformatics #ProteinScience #Pfam #EMBLEBI
June 20, 2025 at 8:23 AM
🚀 InterPro 106.0 is now live!
✨ Updated to Pfam 37.4
✨ 683 new entries added
✨ Enhanced protein classification coverage
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk 💻🧪🧬
#Bioinformatics #ProteinScience #Pfam #EMBLEBI
✨ Updated to Pfam 37.4
✨ 683 new entries added
✨ Enhanced protein classification coverage
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk 💻🧪🧬
#Bioinformatics #ProteinScience #Pfam #EMBLEBI
Reposted by InterPro
What’s new in the redesigned PDBe entry pages?
🧪 Cleaner layout
🧪 Interactive 3D viewers
🧪 Contextual annotations
🧪 Easier navigation
See for yourself:
wwwdev.ebi.ac.uk/pdbe/entry/p...
#PDBeBeta #Bioinformatics #Biochemistry #Science
🧪 Cleaner layout
🧪 Interactive 3D viewers
🧪 Contextual annotations
🧪 Easier navigation
See for yourself:
wwwdev.ebi.ac.uk/pdbe/entry/p...
#PDBeBeta #Bioinformatics #Biochemistry #Science
June 16, 2025 at 3:40 PM
What’s new in the redesigned PDBe entry pages?
🧪 Cleaner layout
🧪 Interactive 3D viewers
🧪 Contextual annotations
🧪 Easier navigation
See for yourself:
wwwdev.ebi.ac.uk/pdbe/entry/p...
#PDBeBeta #Bioinformatics #Biochemistry #Science
🧪 Cleaner layout
🧪 Interactive 3D viewers
🧪 Contextual annotations
🧪 Easier navigation
See for yourself:
wwwdev.ebi.ac.uk/pdbe/entry/p...
#PDBeBeta #Bioinformatics #Biochemistry #Science
Reposted by InterPro
InterPro just got one of its biggest updates ever.
Now with 1.8 billion AI-driven protein annotations, AlphaFold-based TED domains, and viral proteins from the Big Fantastic Virus Database (BFVD).
See it all at www.ebi.ac.uk/interpro
🖥️🧬
@interprodb.bsky.social
Now with 1.8 billion AI-driven protein annotations, AlphaFold-based TED domains, and viral proteins from the Big Fantastic Virus Database (BFVD).
See it all at www.ebi.ac.uk/interpro
🖥️🧬
@interprodb.bsky.social
June 12, 2025 at 3:27 PM
InterPro just got one of its biggest updates ever.
Now with 1.8 billion AI-driven protein annotations, AlphaFold-based TED domains, and viral proteins from the Big Fantastic Virus Database (BFVD).
See it all at www.ebi.ac.uk/interpro
🖥️🧬
@interprodb.bsky.social
Now with 1.8 billion AI-driven protein annotations, AlphaFold-based TED domains, and viral proteins from the Big Fantastic Virus Database (BFVD).
See it all at www.ebi.ac.uk/interpro
🖥️🧬
@interprodb.bsky.social
🦠🧬Exciting news! BFVD predicted viral protein structures are now available in @InterProDB!
For the first time, explore InterPro functional annotations directly on 3D structures of viral proteins not covered by AlphaFold DB. This bridges a critical gap in structural virology research.
For the first time, explore InterPro functional annotations directly on 3D structures of viral proteins not covered by AlphaFold DB. This bridges a critical gap in structural virology research.
June 3, 2025 at 12:47 PM
🦠🧬Exciting news! BFVD predicted viral protein structures are now available in @InterProDB!
For the first time, explore InterPro functional annotations directly on 3D structures of viral proteins not covered by AlphaFold DB. This bridges a critical gap in structural virology research.
For the first time, explore InterPro functional annotations directly on 3D structures of viral proteins not covered by AlphaFold DB. This bridges a critical gap in structural virology research.
We are saddened to hear of the passing of Daniel Kahn, the creator of the ProDom database. His pioneering work in protein domain classification laid important groundwork for InterPro and the wider bioinformatics community. We honour his lasting contributions. 🧬🕊️
May 20, 2025 at 8:29 AM
We are saddened to hear of the passing of Daniel Kahn, the creator of the ProDom database. His pioneering work in protein domain classification laid important groundwork for InterPro and the wider bioinformatics community. We honour his lasting contributions. 🧬🕊️
🧬 MAJOR UPDATE: InterPro-N matches now available in InterPro!
1.8 billion AI-driven protein annotations developed with Google DeepMind are now live.
✨ Look for the sparkles icon to identify them
📊 Options menu lets you view: InterPro only | InterPro-N-only | Stacked
💻🧪
1.8 billion AI-driven protein annotations developed with Google DeepMind are now live.
✨ Look for the sparkles icon to identify them
📊 Options menu lets you view: InterPro only | InterPro-N-only | Stacked
💻🧪
May 15, 2025 at 5:08 PM
🧬 MAJOR UPDATE: InterPro-N matches now available in InterPro!
1.8 billion AI-driven protein annotations developed with Google DeepMind are now live.
✨ Look for the sparkles icon to identify them
📊 Options menu lets you view: InterPro only | InterPro-N-only | Stacked
💻🧪
1.8 billion AI-driven protein annotations developed with Google DeepMind are now live.
✨ Look for the sparkles icon to identify them
📊 Options menu lets you view: InterPro only | InterPro-N-only | Stacked
💻🧪
🔍 NEW: TED domains in InterPro 105.0!
For the first time, see AlphaFold-derived structural domains directly alongside InterPro annotations in one powerful visualisation. Bridging the sequence-structure divide in protein analysis. 💻🧪
Explore now: www.ebi.ac.uk/interpro/pro...
For the first time, see AlphaFold-derived structural domains directly alongside InterPro annotations in one powerful visualisation. Bridging the sequence-structure divide in protein analysis. 💻🧪
Explore now: www.ebi.ac.uk/interpro/pro...
May 8, 2025 at 2:55 PM
🔍 NEW: TED domains in InterPro 105.0!
For the first time, see AlphaFold-derived structural domains directly alongside InterPro annotations in one powerful visualisation. Bridging the sequence-structure divide in protein analysis. 💻🧪
Explore now: www.ebi.ac.uk/interpro/pro...
For the first time, see AlphaFold-derived structural domains directly alongside InterPro annotations in one powerful visualisation. Bridging the sequence-structure divide in protein analysis. 💻🧪
Explore now: www.ebi.ac.uk/interpro/pro...
📝 Check out our new blog post highlighting the groundbreaking features in InterPro 105.0!
Learn how InterPro-N, TED domains and viral protein structures are transforming protein classification: ebi.ac.uk/about/news/u...
Learn how InterPro-N, TED domains and viral protein structures are transforming protein classification: ebi.ac.uk/about/news/u...
May 1, 2025 at 4:35 PM
📝 Check out our new blog post highlighting the groundbreaking features in InterPro 105.0!
Learn how InterPro-N, TED domains and viral protein structures are transforming protein classification: ebi.ac.uk/about/news/u...
Learn how InterPro-N, TED domains and viral protein structures are transforming protein classification: ebi.ac.uk/about/news/u...
📢InterPro release 105.0 is live!
✨Update to Pfam 37.3, PROSITE patterns 2025_01
PROSITE profiles 2025_01 and HAMAP 2025_01
✨342 new entries
✨Addition of InterPro-N annotations
✨Addition of BFVD structure predictions from @martinsteinegger.bsky.social's lab
Have a look: ebi.ac.uk/interpro/htt...
💻🧪🆕
✨Update to Pfam 37.3, PROSITE patterns 2025_01
PROSITE profiles 2025_01 and HAMAP 2025_01
✨342 new entries
✨Addition of InterPro-N annotations
✨Addition of BFVD structure predictions from @martinsteinegger.bsky.social's lab
Have a look: ebi.ac.uk/interpro/htt...
💻🧪🆕
April 24, 2025 at 4:07 PM
📢InterPro release 105.0 is live!
✨Update to Pfam 37.3, PROSITE patterns 2025_01
PROSITE profiles 2025_01 and HAMAP 2025_01
✨342 new entries
✨Addition of InterPro-N annotations
✨Addition of BFVD structure predictions from @martinsteinegger.bsky.social's lab
Have a look: ebi.ac.uk/interpro/htt...
💻🧪🆕
✨Update to Pfam 37.3, PROSITE patterns 2025_01
PROSITE profiles 2025_01 and HAMAP 2025_01
✨342 new entries
✨Addition of InterPro-N annotations
✨Addition of BFVD structure predictions from @martinsteinegger.bsky.social's lab
Have a look: ebi.ac.uk/interpro/htt...
💻🧪🆕
Missed our latest webinar about LLM generated summaries for protein classification at InterPro delivered by
@matthiasblum.bsky.social?
The recording is now available: lnkd.in/ei4fKGXd
@matthiasblum.bsky.social?
The recording is now available: lnkd.in/ei4fKGXd
April 11, 2025 at 8:50 AM
Missed our latest webinar about LLM generated summaries for protein classification at InterPro delivered by
@matthiasblum.bsky.social?
The recording is now available: lnkd.in/ei4fKGXd
@matthiasblum.bsky.social?
The recording is now available: lnkd.in/ei4fKGXd
Want to use the InterPro API but not sure how to start? Join this upcoming workshop, where @typhainepl.bsky.social will guide you through the fundamentals and practical applications. Discover how to integrate this powerful tool into your workflow! Register now to secure your spot. 💻🧪
Would you like to learn how to use @ebi.embl.org resources for #protein characterisation? This one-day workshop will show you how to retrieve protein sequences, identify homologs, annotate functional domains, and explore structural information using REST APIs: ebi.ac.uk/training/eve...
🧶🧬🖥️🧪
🧶🧬🖥️🧪
April 2, 2025 at 9:36 AM
Want to use the InterPro API but not sure how to start? Join this upcoming workshop, where @typhainepl.bsky.social will guide you through the fundamentals and practical applications. Discover how to integrate this powerful tool into your workflow! Register now to secure your spot. 💻🧪
Reposted by InterPro
Are you going to ISMB/ECCB 2025 @iscb.bsky.social in Liverpool 🇬🇧? Register for our tutorial on 'Genomic Variant Interpretation & prioritisation for clinical research'. More info: tinyurl.com/ahav9djn
#genomics #bioinformatics
#genomics #bioinformatics
March 25, 2025 at 2:38 PM
Are you going to ISMB/ECCB 2025 @iscb.bsky.social in Liverpool 🇬🇧? Register for our tutorial on 'Genomic Variant Interpretation & prioritisation for clinical research'. More info: tinyurl.com/ahav9djn
#genomics #bioinformatics
#genomics #bioinformatics
🆕 New version of InterProScan: 5.73-104.0
3 ways to use it:
1️⃣ Sequence search on the InterPro website: ebi.ac.uk/interpro/sea...
2️⃣ Local installation: interproscan-docs.readthedocs.io/en/v5/Instal...
3️⃣ Local installation using a container: interproscan-docs.readthedocs.io/en/v5/HowToU...
💻🧪
3 ways to use it:
1️⃣ Sequence search on the InterPro website: ebi.ac.uk/interpro/sea...
2️⃣ Local installation: interproscan-docs.readthedocs.io/en/v5/Instal...
3️⃣ Local installation using a container: interproscan-docs.readthedocs.io/en/v5/HowToU...
💻🧪
February 25, 2025 at 11:22 AM
🆕 New version of InterProScan: 5.73-104.0
3 ways to use it:
1️⃣ Sequence search on the InterPro website: ebi.ac.uk/interpro/sea...
2️⃣ Local installation: interproscan-docs.readthedocs.io/en/v5/Instal...
3️⃣ Local installation using a container: interproscan-docs.readthedocs.io/en/v5/HowToU...
💻🧪
3 ways to use it:
1️⃣ Sequence search on the InterPro website: ebi.ac.uk/interpro/sea...
2️⃣ Local installation: interproscan-docs.readthedocs.io/en/v5/Instal...
3️⃣ Local installation using a container: interproscan-docs.readthedocs.io/en/v5/HowToU...
💻🧪
Reposted by InterPro
🔈InterPro release 104.0 is live!
✨Update to Pfam 37.2, NCBIfam 17.0, CDD 3.21.
✨661 new entries, including 682 signatures from the Pfam (663), NCBIfam (5), PANTHER (5), CDD (9) databases. Have a look: ebi.ac.uk/interpro/ 💻🧪
✨Update to Pfam 37.2, NCBIfam 17.0, CDD 3.21.
✨661 new entries, including 682 signatures from the Pfam (663), NCBIfam (5), PANTHER (5), CDD (9) databases. Have a look: ebi.ac.uk/interpro/ 💻🧪
February 6, 2025 at 2:19 PM
🔈InterPro release 104.0 is live!
✨Update to Pfam 37.2, NCBIfam 17.0, CDD 3.21.
✨661 new entries, including 682 signatures from the Pfam (663), NCBIfam (5), PANTHER (5), CDD (9) databases. Have a look: ebi.ac.uk/interpro/ 💻🧪
✨Update to Pfam 37.2, NCBIfam 17.0, CDD 3.21.
✨661 new entries, including 682 signatures from the Pfam (663), NCBIfam (5), PANTHER (5), CDD (9) databases. Have a look: ebi.ac.uk/interpro/ 💻🧪