InterPro
@interprodb.bsky.social
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.
ebi.ac.uk/interpro/
ebi.ac.uk/interpro/
🚀InterPro 107.0 is live!
✨Updated to Pfam 38.0
✨1,068 new InterPro entries
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk
✨Updated to Pfam 38.0
✨1,068 new InterPro entries
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk
October 23, 2025 at 12:27 PM
🚀InterPro 107.0 is live!
✨Updated to Pfam 38.0
✨1,068 new InterPro entries
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk
✨Updated to Pfam 38.0
✨1,068 new InterPro entries
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk
Quinoa thrives at 4,000m altitude where many crops struggle. Heat Shock Proteins helps protect plant cells from environmental stress. These molecular mechanisms in traditional crops may inform climate-resilient agriculture strategies. 💻🧪
More info: proteinswebteam.github.io/interpro-blo...
More info: proteinswebteam.github.io/interpro-blo...
October 2, 2025 at 2:59 PM
Quinoa thrives at 4,000m altitude where many crops struggle. Heat Shock Proteins helps protect plant cells from environmental stress. These molecular mechanisms in traditional crops may inform climate-resilient agriculture strategies. 💻🧪
More info: proteinswebteam.github.io/interpro-blo...
More info: proteinswebteam.github.io/interpro-blo...
Feature Spotlight: Taxonomy Sunburst
Discover the taxonomic breadth of your InterPro entry at a glance with our dynamic sunburst chart! 🕸️ 💻🧪🧬
Discover the taxonomic breadth of your InterPro entry at a glance with our dynamic sunburst chart! 🕸️ 💻🧪🧬
August 27, 2025 at 3:55 PM
Feature Spotlight: Taxonomy Sunburst
Discover the taxonomic breadth of your InterPro entry at a glance with our dynamic sunburst chart! 🕸️ 💻🧪🧬
Discover the taxonomic breadth of your InterPro entry at a glance with our dynamic sunburst chart! 🕸️ 💻🧪🧬
InterProScan 6 (beta) is here 🎉
A Nextflow-powered, containerised overhaul for scalable, reproducible protein annotation—decoupled software/data, automated data handling, and smoother runs across HPC and cloud.
Feedback welcome!
github.com/ebi-pf-team/...
💻🧪🧬
A Nextflow-powered, containerised overhaul for scalable, reproducible protein annotation—decoupled software/data, automated data handling, and smoother runs across HPC and cloud.
Feedback welcome!
github.com/ebi-pf-team/...
💻🧪🧬
August 8, 2025 at 9:32 AM
InterProScan 6 (beta) is here 🎉
A Nextflow-powered, containerised overhaul for scalable, reproducible protein annotation—decoupled software/data, automated data handling, and smoother runs across HPC and cloud.
Feedback welcome!
github.com/ebi-pf-team/...
💻🧪🧬
A Nextflow-powered, containerised overhaul for scalable, reproducible protein annotation—decoupled software/data, automated data handling, and smoother runs across HPC and cloud.
Feedback welcome!
github.com/ebi-pf-team/...
💻🧪🧬
🧬 The InterPro/Pfam team will be presenting at #ISMB2025 next week in Liverpool!
🎤 Multiple talks & 📊 posters on protein analysis & classification
💻🧪
🎤 Multiple talks & 📊 posters on protein analysis & classification
💻🧪
July 18, 2025 at 2:11 PM
🧬 The InterPro/Pfam team will be presenting at #ISMB2025 next week in Liverpool!
🎤 Multiple talks & 📊 posters on protein analysis & classification
💻🧪
🎤 Multiple talks & 📊 posters on protein analysis & classification
💻🧪
🧬 The InterPro/Pfam team will be presenting at #ISMB2025 next week in Liverpool!
Join us July 20-24 at the world's largest #bioinformatics conference!
#ISMBECCB2025 #ProteinAnalysis #ComputationalBiology
💻🧪
Join us July 20-24 at the world's largest #bioinformatics conference!
#ISMBECCB2025 #ProteinAnalysis #ComputationalBiology
💻🧪
July 18, 2025 at 2:09 PM
🧬 The InterPro/Pfam team will be presenting at #ISMB2025 next week in Liverpool!
Join us July 20-24 at the world's largest #bioinformatics conference!
#ISMBECCB2025 #ProteinAnalysis #ComputationalBiology
💻🧪
Join us July 20-24 at the world's largest #bioinformatics conference!
#ISMBECCB2025 #ProteinAnalysis #ComputationalBiology
💻🧪
🧬✨ Excited to present at @jobim2025.bsky.social this week in Bordeaux!
🎤 Talk 08/07 16:50, amphi E: Pfam: embracing AI/ML by @typhainepl.bsky.social
📊 Poster #97: InterPro: Accelerating Protein Annotation with AI by @matthiasblum.bsky.social
💻🧪
🎤 Talk 08/07 16:50, amphi E: Pfam: embracing AI/ML by @typhainepl.bsky.social
📊 Poster #97: InterPro: Accelerating Protein Annotation with AI by @matthiasblum.bsky.social
💻🧪
July 7, 2025 at 8:21 AM
🧬✨ Excited to present at @jobim2025.bsky.social this week in Bordeaux!
🎤 Talk 08/07 16:50, amphi E: Pfam: embracing AI/ML by @typhainepl.bsky.social
📊 Poster #97: InterPro: Accelerating Protein Annotation with AI by @matthiasblum.bsky.social
💻🧪
🎤 Talk 08/07 16:50, amphi E: Pfam: embracing AI/ML by @typhainepl.bsky.social
📊 Poster #97: InterPro: Accelerating Protein Annotation with AI by @matthiasblum.bsky.social
💻🧪
Does taste depend on our genes? Discover how variations in taste receptors—from TAS2Rs that gate bitterness to olfactory genes that make cilantro taste soapy—and even pain receptors for spice shape what we love (and hate) on our plates. Read more: proteinswebteam.github.io/interpro-blo... 💻🧪👅🧬
![Schematic diagram showing taste signal transmission between the tongue (with taste buds that contain taste cells harbouring GPCRs) and brain. Taste GPCRs are activated by specific food compounds, recruit specific G proteins that further induce intracellular calcium release. Adapted from [https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28:_Biosignaling_-_Capstone_Volume_I/28.18:_Signal_Transduction_-_Taste_(Gustation)].](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:2b2g3csqntyhbjba6zutidvo/bafkreiarei32po5buevs63s7abazj42rdvx5w7pnszlg2zduhyqlpfqxdu@jpeg)
June 26, 2025 at 9:44 AM
Does taste depend on our genes? Discover how variations in taste receptors—from TAS2Rs that gate bitterness to olfactory genes that make cilantro taste soapy—and even pain receptors for spice shape what we love (and hate) on our plates. Read more: proteinswebteam.github.io/interpro-blo... 💻🧪👅🧬
🚀 InterPro 106.0 is now live!
✨ Updated to Pfam 37.4
✨ 683 new entries added
✨ Enhanced protein classification coverage
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk 💻🧪🧬
#Bioinformatics #ProteinScience #Pfam #EMBLEBI
✨ Updated to Pfam 37.4
✨ 683 new entries added
✨ Enhanced protein classification coverage
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk 💻🧪🧬
#Bioinformatics #ProteinScience #Pfam #EMBLEBI
June 20, 2025 at 8:23 AM
🚀 InterPro 106.0 is now live!
✨ Updated to Pfam 37.4
✨ 683 new entries added
✨ Enhanced protein classification coverage
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk 💻🧪🧬
#Bioinformatics #ProteinScience #Pfam #EMBLEBI
✨ Updated to Pfam 37.4
✨ 683 new entries added
✨ Enhanced protein classification coverage
Explore the latest annotations and discover new protein insights.
Explore it now: interpro.ebi.ac.uk 💻🧪🧬
#Bioinformatics #ProteinScience #Pfam #EMBLEBI
🦠🧬Exciting news! BFVD predicted viral protein structures are now available in @InterProDB!
For the first time, explore InterPro functional annotations directly on 3D structures of viral proteins not covered by AlphaFold DB. This bridges a critical gap in structural virology research.
For the first time, explore InterPro functional annotations directly on 3D structures of viral proteins not covered by AlphaFold DB. This bridges a critical gap in structural virology research.
June 3, 2025 at 12:47 PM
🦠🧬Exciting news! BFVD predicted viral protein structures are now available in @InterProDB!
For the first time, explore InterPro functional annotations directly on 3D structures of viral proteins not covered by AlphaFold DB. This bridges a critical gap in structural virology research.
For the first time, explore InterPro functional annotations directly on 3D structures of viral proteins not covered by AlphaFold DB. This bridges a critical gap in structural virology research.
🧬 MAJOR UPDATE: InterPro-N matches now available in InterPro!
1.8 billion AI-driven protein annotations developed with Google DeepMind are now live.
✨ Look for the sparkles icon to identify them
📊 Options menu lets you view: InterPro only | InterPro-N-only | Stacked
💻🧪
1.8 billion AI-driven protein annotations developed with Google DeepMind are now live.
✨ Look for the sparkles icon to identify them
📊 Options menu lets you view: InterPro only | InterPro-N-only | Stacked
💻🧪
May 15, 2025 at 5:08 PM
🧬 MAJOR UPDATE: InterPro-N matches now available in InterPro!
1.8 billion AI-driven protein annotations developed with Google DeepMind are now live.
✨ Look for the sparkles icon to identify them
📊 Options menu lets you view: InterPro only | InterPro-N-only | Stacked
💻🧪
1.8 billion AI-driven protein annotations developed with Google DeepMind are now live.
✨ Look for the sparkles icon to identify them
📊 Options menu lets you view: InterPro only | InterPro-N-only | Stacked
💻🧪
🔍 NEW: TED domains in InterPro 105.0!
For the first time, see AlphaFold-derived structural domains directly alongside InterPro annotations in one powerful visualisation. Bridging the sequence-structure divide in protein analysis. 💻🧪
Explore now: www.ebi.ac.uk/interpro/pro...
For the first time, see AlphaFold-derived structural domains directly alongside InterPro annotations in one powerful visualisation. Bridging the sequence-structure divide in protein analysis. 💻🧪
Explore now: www.ebi.ac.uk/interpro/pro...
May 8, 2025 at 2:55 PM
🔍 NEW: TED domains in InterPro 105.0!
For the first time, see AlphaFold-derived structural domains directly alongside InterPro annotations in one powerful visualisation. Bridging the sequence-structure divide in protein analysis. 💻🧪
Explore now: www.ebi.ac.uk/interpro/pro...
For the first time, see AlphaFold-derived structural domains directly alongside InterPro annotations in one powerful visualisation. Bridging the sequence-structure divide in protein analysis. 💻🧪
Explore now: www.ebi.ac.uk/interpro/pro...
📝 Check out our new blog post highlighting the groundbreaking features in InterPro 105.0!
Learn how InterPro-N, TED domains and viral protein structures are transforming protein classification: ebi.ac.uk/about/news/u...
Learn how InterPro-N, TED domains and viral protein structures are transforming protein classification: ebi.ac.uk/about/news/u...
May 1, 2025 at 4:35 PM
📝 Check out our new blog post highlighting the groundbreaking features in InterPro 105.0!
Learn how InterPro-N, TED domains and viral protein structures are transforming protein classification: ebi.ac.uk/about/news/u...
Learn how InterPro-N, TED domains and viral protein structures are transforming protein classification: ebi.ac.uk/about/news/u...
📢InterPro release 105.0 is live!
✨Update to Pfam 37.3, PROSITE patterns 2025_01
PROSITE profiles 2025_01 and HAMAP 2025_01
✨342 new entries
✨Addition of InterPro-N annotations
✨Addition of BFVD structure predictions from @martinsteinegger.bsky.social's lab
Have a look: ebi.ac.uk/interpro/htt...
💻🧪🆕
✨Update to Pfam 37.3, PROSITE patterns 2025_01
PROSITE profiles 2025_01 and HAMAP 2025_01
✨342 new entries
✨Addition of InterPro-N annotations
✨Addition of BFVD structure predictions from @martinsteinegger.bsky.social's lab
Have a look: ebi.ac.uk/interpro/htt...
💻🧪🆕
April 24, 2025 at 4:07 PM
📢InterPro release 105.0 is live!
✨Update to Pfam 37.3, PROSITE patterns 2025_01
PROSITE profiles 2025_01 and HAMAP 2025_01
✨342 new entries
✨Addition of InterPro-N annotations
✨Addition of BFVD structure predictions from @martinsteinegger.bsky.social's lab
Have a look: ebi.ac.uk/interpro/htt...
💻🧪🆕
✨Update to Pfam 37.3, PROSITE patterns 2025_01
PROSITE profiles 2025_01 and HAMAP 2025_01
✨342 new entries
✨Addition of InterPro-N annotations
✨Addition of BFVD structure predictions from @martinsteinegger.bsky.social's lab
Have a look: ebi.ac.uk/interpro/htt...
💻🧪🆕
Missed our latest webinar about LLM generated summaries for protein classification at InterPro delivered by
@matthiasblum.bsky.social?
The recording is now available: lnkd.in/ei4fKGXd
@matthiasblum.bsky.social?
The recording is now available: lnkd.in/ei4fKGXd
April 11, 2025 at 8:50 AM
Missed our latest webinar about LLM generated summaries for protein classification at InterPro delivered by
@matthiasblum.bsky.social?
The recording is now available: lnkd.in/ei4fKGXd
@matthiasblum.bsky.social?
The recording is now available: lnkd.in/ei4fKGXd
🆕 New version of InterProScan: 5.73-104.0
3 ways to use it:
1️⃣ Sequence search on the InterPro website: ebi.ac.uk/interpro/sea...
2️⃣ Local installation: interproscan-docs.readthedocs.io/en/v5/Instal...
3️⃣ Local installation using a container: interproscan-docs.readthedocs.io/en/v5/HowToU...
💻🧪
3 ways to use it:
1️⃣ Sequence search on the InterPro website: ebi.ac.uk/interpro/sea...
2️⃣ Local installation: interproscan-docs.readthedocs.io/en/v5/Instal...
3️⃣ Local installation using a container: interproscan-docs.readthedocs.io/en/v5/HowToU...
💻🧪
February 25, 2025 at 11:22 AM
🆕 New version of InterProScan: 5.73-104.0
3 ways to use it:
1️⃣ Sequence search on the InterPro website: ebi.ac.uk/interpro/sea...
2️⃣ Local installation: interproscan-docs.readthedocs.io/en/v5/Instal...
3️⃣ Local installation using a container: interproscan-docs.readthedocs.io/en/v5/HowToU...
💻🧪
3 ways to use it:
1️⃣ Sequence search on the InterPro website: ebi.ac.uk/interpro/sea...
2️⃣ Local installation: interproscan-docs.readthedocs.io/en/v5/Instal...
3️⃣ Local installation using a container: interproscan-docs.readthedocs.io/en/v5/HowToU...
💻🧪
🔈InterPro release 104.0 is live!
✨Update to Pfam 37.2, NCBIfam 17.0, CDD 3.21.
✨661 new entries, including 682 signatures from the Pfam (663), NCBIfam (5), PANTHER (5), CDD (9) databases. Have a look: ebi.ac.uk/interpro/ 💻🧪
✨Update to Pfam 37.2, NCBIfam 17.0, CDD 3.21.
✨661 new entries, including 682 signatures from the Pfam (663), NCBIfam (5), PANTHER (5), CDD (9) databases. Have a look: ebi.ac.uk/interpro/ 💻🧪
February 6, 2025 at 2:19 PM
🔈InterPro release 104.0 is live!
✨Update to Pfam 37.2, NCBIfam 17.0, CDD 3.21.
✨661 new entries, including 682 signatures from the Pfam (663), NCBIfam (5), PANTHER (5), CDD (9) databases. Have a look: ebi.ac.uk/interpro/ 💻🧪
✨Update to Pfam 37.2, NCBIfam 17.0, CDD 3.21.
✨661 new entries, including 682 signatures from the Pfam (663), NCBIfam (5), PANTHER (5), CDD (9) databases. Have a look: ebi.ac.uk/interpro/ 💻🧪
🧬🧪💻 New blog post: Diving deep into the key proteins behind Parkinson's disease. From α-synuclein to LRRK2, we're unravelling the molecular mysteries that could hold the key to treatment breakthroughs. Read more: proteinswebteam.github.io/interpro-blo... #Parkinsons #Neuroscience
January 31, 2025 at 4:19 PM
🧬🧪💻 New blog post: Diving deep into the key proteins behind Parkinson's disease. From α-synuclein to LRRK2, we're unravelling the molecular mysteries that could hold the key to treatment breakthroughs. Read more: proteinswebteam.github.io/interpro-blo... #Parkinsons #Neuroscience
🔍 Lost in InterPro data? Our redesigned Help page has you covered! From quick answers to deep dives into protein families, find exactly what you need at www.ebi.ac.uk/interpro/help/ 💻🧪
January 24, 2025 at 11:03 AM
🔍 Lost in InterPro data? Our redesigned Help page has you covered! From quick answers to deep dives into protein families, find exactly what you need at www.ebi.ac.uk/interpro/help/ 💻🧪
🆕The member database signature pages have undergone a thoughtful reorganisation to improve information accessibility.
1) Curation data are now in Overview
2) HMM information and logo are now in Profile HMM
Have a look: www.ebi.ac.uk/interpro/ent...
1) Curation data are now in Overview
2) HMM information and logo are now in Profile HMM
Have a look: www.ebi.ac.uk/interpro/ent...
January 16, 2025 at 11:39 AM
🆕The member database signature pages have undergone a thoughtful reorganisation to improve information accessibility.
1) Curation data are now in Overview
2) HMM information and logo are now in Profile HMM
Have a look: www.ebi.ac.uk/interpro/ent...
1) Curation data are now in Overview
2) HMM information and logo are now in Profile HMM
Have a look: www.ebi.ac.uk/interpro/ent...
🆕We've implemented a new “Curation status” filter to help users distinguish between different types of entries (curated vs AI) in the Browse by InterPro and Member DB, have a look: www.ebi.ac.uk/interpro/ent... 💻🧪
January 10, 2025 at 5:20 PM
🆕We've implemented a new “Curation status” filter to help users distinguish between different types of entries (curated vs AI) in the Browse by InterPro and Member DB, have a look: www.ebi.ac.uk/interpro/ent... 💻🧪
2024 was a big year for InterPro! 🎉
🔹 Celebrated InterPro 100 with new features
🤖 Added AI-generated entries
🌟 Improved tools & navigation
📚 Expanded data with new signatures
💬 Joined Bluesky to connect with you!
Thank you for your support—here’s to 2025! 🚀
💻🧪
🔹 Celebrated InterPro 100 with new features
🤖 Added AI-generated entries
🌟 Improved tools & navigation
📚 Expanded data with new signatures
💬 Joined Bluesky to connect with you!
Thank you for your support—here’s to 2025! 🚀
💻🧪
December 23, 2024 at 10:33 AM
2024 was a big year for InterPro! 🎉
🔹 Celebrated InterPro 100 with new features
🤖 Added AI-generated entries
🌟 Improved tools & navigation
📚 Expanded data with new signatures
💬 Joined Bluesky to connect with you!
Thank you for your support—here’s to 2025! 🚀
💻🧪
🔹 Celebrated InterPro 100 with new features
🤖 Added AI-generated entries
🌟 Improved tools & navigation
📚 Expanded data with new signatures
💬 Joined Bluesky to connect with you!
Thank you for your support—here’s to 2025! 🚀
💻🧪
📣 A new version of InterProScan (5.72-103.0) is available. You can download it here: ebi.ac.uk/interpro/abo... More info and documentation: interproscan-docs.readthedocs.io/en/latest/Re...
🧪💻🧬
🧪💻🧬
December 12, 2024 at 11:18 AM
📣 A new version of InterProScan (5.72-103.0) is available. You can download it here: ebi.ac.uk/interpro/abo... More info and documentation: interproscan-docs.readthedocs.io/en/latest/Re...
🧪💻🧬
🧪💻🧬
📝 Just published: Our latest blog walks you through InterPro's major updates - from redesigned protein views to improved data exploration. Read more: proteinswebteam.github.io/interpro-blo...
December 9, 2024 at 10:06 AM
📝 Just published: Our latest blog walks you through InterPro's major updates - from redesigned protein views to improved data exploration. Read more: proteinswebteam.github.io/interpro-blo...
InterPro release 103.0 is live! 💻🧪
✨Update to Pfam 37.1
✨1029 new entries, including 1019 signatures from the Pfam (1008), NCBIfam (2), PIRSF (1), PANTHER (1), CDD (7) databases.
Have a look: ebi.ac.uk/interpro/
✨Update to Pfam 37.1
✨1029 new entries, including 1019 signatures from the Pfam (1008), NCBIfam (2), PIRSF (1), PANTHER (1), CDD (7) databases.
Have a look: ebi.ac.uk/interpro/
November 29, 2024 at 8:29 AM
InterPro release 103.0 is live! 💻🧪
✨Update to Pfam 37.1
✨1029 new entries, including 1019 signatures from the Pfam (1008), NCBIfam (2), PIRSF (1), PANTHER (1), CDD (7) databases.
Have a look: ebi.ac.uk/interpro/
✨Update to Pfam 37.1
✨1029 new entries, including 1019 signatures from the Pfam (1008), NCBIfam (2), PIRSF (1), PANTHER (1), CDD (7) databases.
Have a look: ebi.ac.uk/interpro/