Staphylococcus aureus has undergone metabolic remodeling to adapt to the dairy niche.

<span><i>Staphylococcus aureus</i> is a major cause of skin and soft tissue infections, and persistent skin colonization is a significant risk factor for infection. Antimicrobial fatty acids (AFAs), produced...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Staphylococcus aureus is a leading cause of both community and hospital-acquired infection worldwide. In addition, S. aureus is resistant to many commonly used antibiotics, which make the treatment of bacteremia, infective endocarditis, and other invasive diseases more challenging. It is essential to obtain a basic understanding of how S. aureus survives in a variety of host niches, including those niches where S. aureus is dependent upon amino acid catabolism. We hypothesize that arginine acquisition is critical for S. aureus pathogenesis; therefore, identifying these transporters is essential for the development of novel therapeutic strategies.

The pathogen Staphylococcus aureus can invade and replicate within human cells. Here, Rodrigues Lopes et al. use an image-based screening approach to identify S. aureus factors important for invasion,...

The signals triggering activation of VraTSR, a key regulator of the cell wall stress response in Staphylococcus aureus, remain unknown. Combining crosslinking assays with vancomycin- and ampicillin-d....

The permeability of bacterial porins is dynamically regulated by periplasmic proton and potassium concentrations, altering antibiotic resistance.

PhD Project - EASTBIO How do transporters promote the fitness of Staphylococcus aureus in different host-species ? at University of Edinburgh, listed on FindAPhD.com

Dihydrodichlorofluorescein derivatives have been employed as reporters of intracellular reactive oxygen species (ROS) in innumerable studies. Their...

Abstract. The human nasal microbiome can serve as a reservoir for pathogens. In particular, the opportunistic pathogen Staphylococcus aureus can be a membe

The skin microbiome is dominated by a few key genera, among which Staphylococcus is one of the most well characterized. Recent studies have examined the roles of various Staphylococcus species such as...

Iron (Fe) is an essential nutrient for S. aureus survivability and pathogenesis, but excess Fe can catalyze the formation of toxic oxygen radicals, em…

Author summary The environments where bacterial pathogens thrive are often rich in proteins and their degradation products, including oligopeptides, which can be taken up by the bacterium and used as ...

Nasal colonization by Staphylococcus aureus is linked with depression in a human cohort and shown in a mouse model to cause decreased serotonin and dopamine in the brain.

The incidence of Staphylococcus aureus bacteremia is on a steady incline in many parts of the world. Given the associated mortality rates have changed little in the last 10 years, this is a major heal...

Commensal Candida albicans enhances the virulence and dissemination of Salmonella enterica subsp. enterica serovar Typhimurium.

Antibiotic resistance is among the greatest threats of the modern era. Multidrug efflux pumps expel antibiotics from bacterial cells and present a particular challenge by conferring resistance to a br...