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idvilchez.bsky.social
@idvilchez.bsky.social
Reposted
Case Report @thelancet.bsky.social ID Grand Rounds:

Endocarditis of aortic/mitral valves and myocarditis due to syphilis! Discussion of cardiovascular syphilis history too

Wasn't on my DDx for Cx neg IE!

www.thelancet.com/journals/lan...
January 22, 2025 at 2:10 AM
late 60s no comorbodites, with P. aeruginosa left knee periprosthetic joint infection. Few years ago had first L knee PJI with P. aeruginosa treated with DAIR and 6 weeks cefepime. Seem like recurrent infection, what surgical approach would you consider
January 22, 2025 at 11:06 PM
Reposted
New study in @cidjournal.bsky.social from France looking at molds (no yeast/dimorphics) found in blood cultures.

n=80 isolates from 2012-2022

2/3rds were Fusarium, 10% Lomentospora, 5% Trichoderma, 5% Mucorales, 5% Aspergillus

70% Hematologic malignancies

academic.oup.com/cid/advance-...
January 10, 2025 at 6:53 PM
do you think we should routinely test Enterobacterales for the presence of ESBL or just base or treatment on ceftriaxone Resistance? How would you treat this UTI with bacteremia (assuming is TMP-SMX qnd FQ resistant)
January 9, 2025 at 12:51 PM
Reposted
If you have a large volume of PD patients, and you don’t do this, you will see fungal peritonitis

It’s a 1B from @ispd1.bsky.social www.nephjc.com/news/ispd202...

I can’t imagine the replies which say you need not 🤦🏽‍♂️

Also came up on the pod: www.nephjc.com/freelyfilter...
January 9, 2025 at 12:00 PM
January 9, 2025 at 2:58 AM
January 9, 2025 at 2:26 AM
Reposted
I tend not to but understand if people do it. Once patients get fungal peritonitis the nephrologists tend to remove the catheter and put them on HD which can have a big impact on QoL.
January 9, 2025 at 2:22 AM
Reposted
I really didn’t know heteroresistance in staph aureus was also a thing. But the lab is supposed to report as R if mec A gene found.

pmc.ncbi.nlm.nih.gov/articles/PMC...
Reversion From Methicillin Susceptibility to Methicillin Resistance in Staphylococcus aureus During Treatment of Bacteremia
Approximately 3% of Staphylococcus aureus strains that, according to results of conventional phenotypic methods, are highly susceptible to methicillin-like antibiotics also have polymerase chain react...
pmc.ncbi.nlm.nih.gov
January 9, 2025 at 2:15 AM
how would you treat and ICD infection with lead and valvular vegetation that grew Staph aureus mecA gene positive per Biofire but Oxacillin susceptible per routine blood culture? Would you treat as MSSA with cefazolin or as MRSA with Vanco or Dapto ?
January 9, 2025 at 1:59 AM
Reposted
Its imperfect data. But its some data and it suggests benefit. 5% absolute reduction in the RCT.

I consider this to be a fairly low risk, high reward intervention. Short courses of fluc are generally well tolerated and there is evidence of benefit that's better than many things we do in ID
January 8, 2025 at 9:31 PM
Reposted
I usually follow the kidney society guidelines for PD peritonitis, which does recommend it.

There is some evidence to support its use, albeit not the highest quality:
Cochrane Review: pmc.ncbi.nlm.nih.gov/articles/PMC...
SR/MA: www.sciencedirect.com/science/arti...
The efficacy of fluconazole for anti-fungal prophylaxis in peritoneal dialysis patients: A systematic review and meta-analysis
La eficacia de fluconazol como estrategia profiláctica en los pacientes con enfermedad renal crónica (ERC) sometidos a diálisis peritoneal (DP) con ex…
www.sciencedirect.com
January 8, 2025 at 3:29 PM
if you have a patient with peritoneal dialysis catheter related peritonitis and you decide to treat with PO and/or intraperitoneal antibiotics, do you routinely recommend fluconazole prophylaxis?
January 8, 2025 at 2:50 PM
Reposted
The Four Moments of Antibiotic Decision Making
Random image #idsky #medsky #AMSsky
December 2, 2024 at 7:39 PM
Reposted
🆕 #Breakpoints Episode: Drs. @annegretemartson.bsky.social, Megan Wimmer, and Evan Clemens join me to discuss all things (Val)ganciclovir!!! #idsky #pharmsky #amssky @sidpharm.bsky.social

🎧 sidp.pinecast.co
November 29, 2024 at 3:47 PM
Reposted
"If you’re going to give antibiotics to patients who don’t need them, at least do the courtesy of giving them for a brief period of time." #IDQuotes @bradspellberg.bsky.social
#idsky #medsky #AMSsky #utisky
December 2, 2024 at 7:28 PM
Reposted
The ‘Big Five’ carbapenemases:
1️⃣VIM
2️⃣IMP
3️⃣NDM
4️⃣KPC
5️⃣OXA-48
🌟Timeline representing the introduction of carbapenems & the appearance of carbapenemases worldwide. 🌟 #idsky #medsky #microsky
November 29, 2024 at 11:02 AM
Reposted
Inaugural article in a new section in @cidjournal.bsky.social called

“Clinical Dilemmas in Infectious Diseases”

led by IDMedEd superstars Daniel Minter and Varun Phadke designed to teach clinical reasoning

Rewriting the Script

academic.oup.com/cid/advance-... #IDSky
Rewriting the Script
Natasha Spottiswoode, MD DPhil, Daniel J Minter, MD, Rachel Friedman-Moraco, MD; Rewriting the Script, Clinical Infectious Diseases, , ciae589, https://doi
academic.oup.com
November 27, 2024 at 2:00 PM
Harper's Bazaar, November 1933, by Romain de Tirtoff aka Erté
November 27, 2024 at 9:12 PM
Reposted
#IDsky
I’m currently going through my old twitter feed to find old posts I liked to find out who’s missing from 🦋
LBaddour
Javier Villafuerte
IDdocAdi
Marc Scheetz
German Esparza
Jason Pogue
Hemi Sulaiman
Brad Spellberg
Sumon Chakrabati
Zain Chagla
Jose Montoya
Lance Burkhart
Jake Scott
Laura Marks
November 27, 2024 at 8:14 PM
Reposted
🆕🔥"Is Antibiotic De-Escalation Safe and Beneficial to Patients with Sepsis?"
Our new article is out today:
👇
#IDSky #MedSky #PCCSky #ICUSky #emimcc #Ansky #EMSky #AMSSky #TxID #meded #Pharmsky #RXSky
@unmc.bsky.social @unmccom.bsky.social
⬇️
bit.ly/4g7bGLE
Validate User
bit.ly
November 27, 2024 at 8:21 PM
Reposted
November 27, 2024 at 2:45 AM
Reposted
Amazing news! HHS has determined that clinical research is no longer required for donors with HIV to donate their kidneys and livers for transplantation in the United States! Thank you to all the HOPE in Action teams and all the advocates for our patients!
www.federalregister.gov/documents/20...
Organ Procurement and Transplantation: Implementation of the HIV Organ Policy Equity (HOPE) Act
The Department of Health and Human Services (HHS) amends the regulations implementing the National Organ Transplant Act of 1984, as amended (NOTA), to remove clinical research and institutional review...
www.federalregister.gov
November 27, 2024 at 3:42 PM
Reposted
New virtual meeting for Immunocompromised Host Society: Addressing the Landscape of CMV Management in Transplant Recipients. Free to members or $25 plus a free membership for those not already members!

Forward on to your residents, fellows, grad students, and international colleagues

#TxID #CMV
November 18, 2024 at 7:50 PM