Andre Kalil, MD MPH
drandrekalil.bsky.social
Andre Kalil, MD MPH
@drandrekalil.bsky.social
Practicing Doc, Transplant ID Director, ID/Critical Care, Clinical Researcher & Trialist. Professor, University of Nebraska Medical Center, Omaha.
Pinned
Hope to learn and share scientific knowledge within this new space.
Reposted by Andre Kalil, MD MPH
We already know ESR/CRP are zombie tests...this SRMA suggests that their role in the definition of PJI is questionable given their lack of sensitivity/specificity, etc. Same with other inflammatory markers like IL-6
November 14, 2025 at 3:05 PM
Reposted by Andre Kalil, MD MPH
Reposted by Andre Kalil, MD MPH
Drs. Natalia Castillo, @drandrekalil.bsky.social & Carlos Gomez published this interesting case report of a prostatic abscess from Ureaplsma parvum in a patient with a heart transplant using NGS #IDSky

onlinelibrary.wiley.com/doi/10.1155/...
Prostatic Abscess due to Ureaplasma parvum in a Heart Transplant Recipient: Diagnostic Challenges and Clinical Utility of Metagenomics Next‐Generation Sequencing (NGS)
Ureaplasma spp. are small and fastidious bacteria that may cause urogenital infections in healthy adults and, in rare cases, invasive disease. These bacteria have been increasingly recognized in immu...
onlinelibrary.wiley.com
November 14, 2025 at 3:08 PM
Aurora Borealis in Omaha-Nebraska tonight is quite an amazing view!
November 13, 2025 at 5:20 AM
Reposted by Andre Kalil, MD MPH
Just 4 weeks to CCR Down Under 2025!

Join us to hear the results of 8 major critical care trials - in person or virtually

➡️ ImmunoSep
➡️ iRehab
➡️ CLIP II
➡️ ACTiVE
➡️ ARISE AFRICA
➡️ RSI
➡️ VITaCCA
➡️ ECMO REHAB

https://criticalcarereviews.com/meetings/ccr-down-under-2025
November 11, 2025 at 10:10 PM
Reposted by Andre Kalil, MD MPH
#Antimicrobials2026
Don’t miss Symposium 2! 🎯 Better Diagnostics, Optimal Treatment
💊@angelahuttner.bsky.social Biomarkers of Infection
💊Lito Papanicolas: Can AMS Protect your Microbiome?
💊Krispin Hajkowicz: Metagenomics

Register now: www.antimicrobials.com.au
#idsky #amssky #microsky #medsky
October 23, 2025 at 6:11 AM
Reposted by Andre Kalil, MD MPH
New on The SHEA Podcast!

Dr. Jonathan Ryder and Dr. Aditi Ramakrishnan discuss the intersection of sexually transmitted infections and antimicrobial stewardship.

Listen now: bit.ly/488Ar9I
October 17, 2025 at 9:08 PM
💥🆕“Plasma Microbial Cell-Free DNA Sequencing in Transplant and Hematologic Patients—Promise, Pitfalls, and Path Forward”
👇Free Access
bit.ly/3KzihEu
@cmijournal.bsky.social #IDSky #MedSky #PCCSky #EMIMC #AMSSky #TxID #meded #Pharmsky #RXSky #MicroSky #ClinMicro @unmc.bsky.social @unmc-id.bsky.social
Plasma microbial cell-free DNA sequencing in transplant and haematologic patients—promise, pitfalls, and path forward
bit.ly
October 8, 2025 at 10:58 PM
Reposted by Andre Kalil, MD MPH
Drs. Gomez, Scherger, Abbas & @drandrekalil.bsky.social published a fascinating paper in @cmijournal.bsky.social on novel diagnostic testing:

"Plasma Microbial Cell-Free DNA Sequencing in Transplant and Hematologic Patients-Promise, Pitfalls, and Path Forward"

pubmed.ncbi.nlm.nih.gov/40946803/
Plasma Microbial Cell-Free DNA Sequencing in Transplant and Hematologic Patients-Promise, Pitfalls, and Path Forward - PubMed
Plasma Microbial Cell-Free DNA Sequencing in Transplant and Hematologic Patients-Promise, Pitfalls, and Path Forward
pubmed.ncbi.nlm.nih.gov
September 25, 2025 at 7:50 PM
Reposted by Andre Kalil, MD MPH
The 2nd #Communicable & #Breakpoints collaboration drops on 19 Sept! Hosts @angelahuttner.bsky.social & @erinmccreary.bsky.social invite BALANCE trial leads Nick Daneman & Robert Fowler to discuss everything from the trial's humble start to its meteoric impact in clinical practice.
#IDSky #clinmicro
September 16, 2025 at 11:42 AM
🆕 “Individualised duration of treatment in febrile urinary tract infection: ready for prime time?”
Excellent article just out by @jesusrbano.bsky.social and Zaira Palacios-Baena @lancetID.bsky.social👇
www.thelancet.com/journals/lan...
Individualised duration of treatment in febrile urinary tract infection: ready for prime time?
The duration of antimicrobial treatment is currently a hot topic in the field of infectious diseases. For decades, the prevailing belief was that long treatments were essential to prevent relapses. Th...
www.thelancet.com
September 14, 2025 at 8:43 PM
Reposted by Andre Kalil, MD MPH
Calls for editorial fellows for ESCMID's two journals, @cmijournal.bsky.social & @cmicomms.bsky.social, are closing soon! Don't miss the chance to be part of shaping and growing the journals and your career!
CMI (due 01 Sept): ow.ly/rifq50WBUfy
CMI Comms (due 15 Sept) ow.ly/F43F50WBUfw

#IDSky
August 27, 2025 at 8:24 AM
Reposted by Andre Kalil, MD MPH
Benefit of Early Oseltamivir Therapy for Adults Hospitalized With Influenza A: An Observational Study
Benefit of Early Oseltamivir Therapy for Adults Hospitalized With Influenza A: An Observational Study
Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare neuroimmunological disorder with diverse etiologies, including infection-associated triggers such as human immunodeficiency virus (HIV) infection.
bit.ly
August 27, 2025 at 12:20 AM
Reposted by Andre Kalil, MD MPH
A Systematic Review and Meta-analysis of the Effectiveness of Remdesivir to Treat SARS-CoV-2 in Hospitalized Patients: Have the Guidelines Evolved With the Evidence?
A Systematic Review and Meta-analysis of the Effectiveness of Remdesivir to Treat SARS-CoV-2 in Hospitalized Patients: Have the Guidelines Evolved With the Evidence?
Clinical practice guidelines (CPGs) aim to reduce variability in practice in order to improve the quality of care by establishing best practice standards [1, 2]. With no definitive standardized approach to developing CPGs, there are inconsistencies in identifying, appraising, and synthesizing...
bit.ly
August 24, 2025 at 10:16 PM
Reposted by Andre Kalil, MD MPH
Our two journals, CMI and CMI Communications, have open calls for editorial fellows. Read more about their respective programmes on their webpages and deadlines:
CMI @cmijournal.bsky.social ow.ly/HTBL50WBUfv
CMI Comms @cmicomms.bsky.social ow.ly/FJkF50WBUfz

#IDSky #clinmicro
August 10, 2025 at 3:58 PM
Reposted by Andre Kalil, MD MPH
Excited to share our work on the epidemiology of diarrheal pathogens using multiplex PCR gastrointestinal panels, led by the amazing medical student, Jeffrey Shu and now published in @cmijournal.bsky.social! 🎉 Kudos to all! #CCLCM #AWSOM shorturl.at/kTWqt
August 20, 2025 at 4:00 AM
Reposted by Andre Kalil, MD MPH
August 24, 2025 at 5:05 AM
Reposted by Andre Kalil, MD MPH
#ASABreakpoint
In vitro, combos look powerful. In practice? Not always.
@angelahuttner.bsky.social reminds us “first, do no harm” Trials show limited benefit + higher toxicity
Are we relying too much on combo therapy in real-world care?
Read: www.asainc.net.au/newsletters/
@gardp.bsky.social #REVIVE
August 22, 2025 at 10:25 AM
Reposted by Andre Kalil, MD MPH
The new #ASA #Breakpoint Newsletter is out🎉
🩺 Chris Robson’s PhD reshaping #infectiveendocarditis care
🔬 AUSCAST guidance on aminopenicillin breakpoints
📊 2024 AGAR: ESBL rates 📈
💊 @angelahuttner.bsky.social antibiotic combos
📷 Photo quiz: #unvaccinated infant
Read: www.asainc.net.au/newsletters
August 22, 2025 at 10:10 AM
Reposted by Andre Kalil, MD MPH
My editorial in JAMA Health Forum: To support the academic research enterprise, we should pursue regulatory reforms that enable institutions to advance more of their discoveries to patients and, in doing so, capture more economic value of innovations they achieve

jamanetwork.com/journals/jam...
Securing America’s Pharmaceutical Innovation Edge
This JAMA Forum discusses challenges to the US’s standing as a global leader in biomedical innovation from China, in the context of recent reductions in funding for biomedical research by the federal ...
jamanetwork.com
August 21, 2025 at 6:18 PM
Reposted by Andre Kalil, MD MPH
Less than one week until #WTC2025! Will we see you there?? #TxID #IDSky
July 28, 2025 at 1:47 PM
Reposted by Andre Kalil, MD MPH
Excited to be a part of this great group of collaborators on this latest work on blood culture contamination & BCx practices across 52 centers

Tons of credit to Valeria Fabre for leading this group!

#IDSky

journals.asm.org/doi/full/10....
Multicenter evaluation of blood culture contamination and blood cultures practices in US acute care hospitals: time for standardization | Journal of Clinical Microbiology
Blood culture contamination (BCC) is associated with patient harm and unnecessary use of healthcare resources. BCC thresholds have been established; however, multiple BCC definitions exist. There is l...
journals.asm.org
July 17, 2025 at 2:51 PM