Steven Pergam, MD, MPH
@pergamic.bsky.social
Transplant ID Doc and IP Director @Fred Hutchinson Cancer Center/ Faculty @UWMedicine. #InfectionPrevention #TxID #vaccines #prevention #protection #medtwitter
Posts/comments are my own and not reflective of my institutions.
Posts/comments are my own and not reflective of my institutions.
Reposted by Steven Pergam, MD, MPH
This Week! Register now to unlock key insights on HSV Infections in this upcoming ICHS webinar! Free for ICHS members + select attendees/$25 for non-members. Register at: ichs.org
November 10, 2025 at 12:00 AM
This Week! Register now to unlock key insights on HSV Infections in this upcoming ICHS webinar! Free for ICHS members + select attendees/$25 for non-members. Register at: ichs.org
A major loss for everyone trying to understand how to prevent respiratory viruses and other major pathogens worldwide.
Sharing data assures we are prepared.
Now we are not
Sharing data assures we are prepared.
Now we are not
On Oct 1, 2025, GISAID informed us that they had ended updates to the flat file of SARS-CoV-2 genomic sequences and associated metadata that we had used to update Nextstrain analyses since Feb 2020. GISAID's stated rationale was that their "resources are limited". 1/5
November 7, 2025 at 7:42 PM
A major loss for everyone trying to understand how to prevent respiratory viruses and other major pathogens worldwide.
Sharing data assures we are prepared.
Now we are not
Sharing data assures we are prepared.
Now we are not
Reposted by Steven Pergam, MD, MPH
On Oct 1, 2025, GISAID informed us that they had ended updates to the flat file of SARS-CoV-2 genomic sequences and associated metadata that we had used to update Nextstrain analyses since Feb 2020. GISAID's stated rationale was that their "resources are limited". 1/5
November 6, 2025 at 9:46 PM
On Oct 1, 2025, GISAID informed us that they had ended updates to the flat file of SARS-CoV-2 genomic sequences and associated metadata that we had used to update Nextstrain analyses since Feb 2020. GISAID's stated rationale was that their "resources are limited". 1/5
Reposted by Steven Pergam, MD, MPH
Not recommending COVID vaccines for healthcare workers is a disaster waiting to happen. Great piece from @drjudystone.bsky.social and Judith Feinberg. www.statnews.com/2025/10/30/c...
Health care workers under 65 must be vaccinated against Covid
The vaccination status of health care workers under 65 has profound implications for millions of Americans.
www.statnews.com
October 30, 2025 at 8:59 PM
Not recommending COVID vaccines for healthcare workers is a disaster waiting to happen. Great piece from @drjudystone.bsky.social and Judith Feinberg. www.statnews.com/2025/10/30/c...
Reposted by Steven Pergam, MD, MPH
Got a great session idea for next year's @idweek.bsky.social ? You can submit either a full symposium or a quick topic or speaker idea ! #medEd #IDfellow #TID #IDSky @idsainfo.bsky.social #IDWeek2025 idweek.org/program/
Program - IDWeek
Have a great idea for a session next year? IDWeek want to hear your ideas! Submit a session suggestion for the 2026 conference by Oct. 31. You have options!
idweek.org
October 30, 2025 at 3:16 AM
Got a great session idea for next year's @idweek.bsky.social ? You can submit either a full symposium or a quick topic or speaker idea ! #medEd #IDfellow #TID #IDSky @idsainfo.bsky.social #IDWeek2025 idweek.org/program/
Reposted by Steven Pergam, MD, MPH
Reposted by Steven Pergam, MD, MPH
New study shows antagonism between olorofim and voriconazole in vitro, suggesting this may be a class effect
academic.oup.com/jac/advance-... #MedMycoSky #TxID #IDSky
academic.oup.com/jac/advance-... #MedMycoSky #TxID #IDSky
October 27, 2025 at 2:58 PM
New study shows antagonism between olorofim and voriconazole in vitro, suggesting this may be a class effect
academic.oup.com/jac/advance-... #MedMycoSky #TxID #IDSky
academic.oup.com/jac/advance-... #MedMycoSky #TxID #IDSky
Reposted by Steven Pergam, MD, MPH
ICHS is an ESCMID Affiliated Society. Together we strive to strengthen the vibrant collaboration among worldwide experts & specialists in the field. ESCMID opportunities and programs are listed on the ICHS website. ICHS.org
October 27, 2025 at 4:01 AM
ICHS is an ESCMID Affiliated Society. Together we strive to strengthen the vibrant collaboration among worldwide experts & specialists in the field. ESCMID opportunities and programs are listed on the ICHS website. ICHS.org
Reposted by Steven Pergam, MD, MPH
From UW/FHCC Dr Michael Boeckh:
Inclusion of immunocompromised individuals in clinical trials of influenza antivirals is essential to ensure that ICIs have equitable access to valuable interventions. #IDSKy
academic.oup.com/jid/article/...
Inclusion of immunocompromised individuals in clinical trials of influenza antivirals is essential to ensure that ICIs have equitable access to valuable interventions. #IDSKy
academic.oup.com/jid/article/...
Influenza Antivirals for Prevention and Treatment in Immunocompromised People
Antivirals are an important backbone for the prevention and treatment of influenza in immunocompromised individuals, who are prone to prolonged viral shedd
academic.oup.com
October 24, 2025 at 11:11 PM
From UW/FHCC Dr Michael Boeckh:
Inclusion of immunocompromised individuals in clinical trials of influenza antivirals is essential to ensure that ICIs have equitable access to valuable interventions. #IDSKy
academic.oup.com/jid/article/...
Inclusion of immunocompromised individuals in clinical trials of influenza antivirals is essential to ensure that ICIs have equitable access to valuable interventions. #IDSKy
academic.oup.com/jid/article/...
Reposted by Steven Pergam, MD, MPH
In the past 2 weeks several European countries have reported locally acquired cases of #mpox clade Ib.
This is new. There had been patients before but those infections likely happened elsewhere.
Now it looks like mpox Ib is spreading here in the sexual networks of men who have sex with men.
#IDsky
This is new. There had been patients before but those infections likely happened elsewhere.
Now it looks like mpox Ib is spreading here in the sexual networks of men who have sex with men.
#IDsky
October 24, 2025 at 12:21 PM
Reposted by Steven Pergam, MD, MPH
Due to the USG Shutdown, I wasn’t able to attend or present @idweek.bsky.social. I was supposed to give the talk on top viral studies that will impact your practice. Here are the papers I was going to highlight:
See next posts
See next posts
October 22, 2025 at 1:36 PM
Due to the USG Shutdown, I wasn’t able to attend or present @idweek.bsky.social. I was supposed to give the talk on top viral studies that will impact your practice. Here are the papers I was going to highlight:
See next posts
See next posts
Reposted by Steven Pergam, MD, MPH
Important Ongoing Studies where we have or will have publications soon:
Pritelivir for refractory or resistant HSV (presented @idweek.bsky.social by @kottonnelson.bsky.social): www.aicuris.com/press-releas...
CD388 for prevention of influenza: www.cidara.com/news/cidara-...
Pritelivir for refractory or resistant HSV (presented @idweek.bsky.social by @kottonnelson.bsky.social): www.aicuris.com/press-releas...
CD388 for prevention of influenza: www.cidara.com/news/cidara-...
Aicuris Announces Pritelivir Met Primary Endpoint in Immunocompromised Herpes Simplex Virus-infected Patients in Phase 3 Pivotal Trial - Aicuris
Aicuris today announced that the Phase 3 trial of its lead candidate pritelivir has met its primary and secondary endpoint. The aim of the trail was to evaluate
www.aicuris.com
October 22, 2025 at 1:40 PM
Important Ongoing Studies where we have or will have publications soon:
Pritelivir for refractory or resistant HSV (presented @idweek.bsky.social by @kottonnelson.bsky.social): www.aicuris.com/press-releas...
CD388 for prevention of influenza: www.cidara.com/news/cidara-...
Pritelivir for refractory or resistant HSV (presented @idweek.bsky.social by @kottonnelson.bsky.social): www.aicuris.com/press-releas...
CD388 for prevention of influenza: www.cidara.com/news/cidara-...
Reposted by Steven Pergam, MD, MPH
October 21, 2025 at 10:27 PM
Reposted by Steven Pergam, MD, MPH
🥳 A huge crowd gathered at the #IHCoP #BugHub stage to listen to #AlpanaWaghmere, #StellaRadosta & #GabrielMotoa discuss #ChallengingCases in #TxID!! #IDWEEK2025
October 20, 2025 at 9:24 PM
🥳 A huge crowd gathered at the #IHCoP #BugHub stage to listen to #AlpanaWaghmere, #StellaRadosta & #GabrielMotoa discuss #ChallengingCases in #TxID!! #IDWEEK2025
Reposted by Steven Pergam, MD, MPH
The US is on track to lose its measles elimination status this year or early next year.
The current public health leadership seems intent to ignore the outbreak until more children die avoidable deaths.
The vaccine is the most effective way to end the outbreak.
www.cidrap.umn.edu/measles/more...
The current public health leadership seems intent to ignore the outbreak until more children die avoidable deaths.
The vaccine is the most effective way to end the outbreak.
www.cidrap.umn.edu/measles/more...
More measles in South Carolina as US nears 1,600 confirmed cases
www.cidrap.umn.edu
October 15, 2025 at 9:27 PM
The US is on track to lose its measles elimination status this year or early next year.
The current public health leadership seems intent to ignore the outbreak until more children die avoidable deaths.
The vaccine is the most effective way to end the outbreak.
www.cidrap.umn.edu/measles/more...
The current public health leadership seems intent to ignore the outbreak until more children die avoidable deaths.
The vaccine is the most effective way to end the outbreak.
www.cidrap.umn.edu/measles/more...
Reposted by Steven Pergam, MD, MPH
Trump’s proposing removal of aluminum salts from vaccines. Half of childhood vaccines rely on them (hep A/B, DTaP, Hib, HPV, meningo/pneumococcal). That change would take years, cost billions, and expose millions to preventable diseases despite zero evidence of harm.
www.nytimes.com/2025/10/15/h...
www.nytimes.com/2025/10/15/h...
Trump Rattles Vaccine Experts Over Aluminum
www.nytimes.com
October 16, 2025 at 2:40 AM
Trump’s proposing removal of aluminum salts from vaccines. Half of childhood vaccines rely on them (hep A/B, DTaP, Hib, HPV, meningo/pneumococcal). That change would take years, cost billions, and expose millions to preventable diseases despite zero evidence of harm.
www.nytimes.com/2025/10/15/h...
www.nytimes.com/2025/10/15/h...
Reposted by Steven Pergam, MD, MPH
The entire HR department at the CDC is gone. Everyone at the IRB, which makes sure studies are conducted ethically and rigorously, and the ethics office, which oversee conflicts of interest for CDC leaders and advisory committee members, were also let go.
www.theguardian.com/us-news/2025...
www.theguardian.com/us-news/2025...
‘Instability and confusion’ as CDC slashes 1,300 jobs before reinstating half
Trump administration says 700 notices were sent in error, while top CDC officer says ‘they didn’t think through what they were doing’
www.theguardian.com
October 14, 2025 at 3:13 PM
The entire HR department at the CDC is gone. Everyone at the IRB, which makes sure studies are conducted ethically and rigorously, and the ethics office, which oversee conflicts of interest for CDC leaders and advisory committee members, were also let go.
www.theguardian.com/us-news/2025...
www.theguardian.com/us-news/2025...
Such valuable data and expertise lost.
Hard to improve health when we don’t even know what is happening.
Call your senators and reps to push back - our voices do make a difference
Hard to improve health when we don’t even know what is happening.
Call your senators and reps to push back - our voices do make a difference
Ugh... This study has existed for decades, providing valuable health data for all sorts of topics and publications. This is just more awful news. 🛟😷 Sociology medsky
CDC team running top survey on health and nutrition is laid off
NHANES has collected data on eating patterns, diabetes, and other common diseases for decades. The CDC team that runs it has been fired.
www.statnews.com
October 15, 2025 at 4:34 PM
Such valuable data and expertise lost.
Hard to improve health when we don’t even know what is happening.
Call your senators and reps to push back - our voices do make a difference
Hard to improve health when we don’t even know what is happening.
Call your senators and reps to push back - our voices do make a difference
Reposted by Steven Pergam, MD, MPH
👉 10/20/25: 5-5:25pm TID fellows, Drs. Gabriel Motoa Cardona (Columbia Presbyterian-Cornell) and Stella Radosta (UT Southwestern) will each present a case, with discussions led by Drs. Alan Koff (UC Davis) and Alpana Waghmare (University of Washington/Fred Hutch)
October 10, 2025 at 2:41 PM
👉 10/20/25: 5-5:25pm TID fellows, Drs. Gabriel Motoa Cardona (Columbia Presbyterian-Cornell) and Stella Radosta (UT Southwestern) will each present a case, with discussions led by Drs. Alan Koff (UC Davis) and Alpana Waghmare (University of Washington/Fred Hutch)
Reposted by Steven Pergam, MD, MPH
💥Transplant ID colleagues attending #IDWeek2025, please mark your calendars 💥
👉 10/20/25: 8-8:25am Dr. Jeremy Walker (UAB) is our invited speaker on “Bridging the Gap between General and TID Practice”, moderated by Drs. Andrea Zimmer and Emily Eichenberger
👉 10/20/25: 8-8:25am Dr. Jeremy Walker (UAB) is our invited speaker on “Bridging the Gap between General and TID Practice”, moderated by Drs. Andrea Zimmer and Emily Eichenberger
October 10, 2025 at 2:41 PM
💥Transplant ID colleagues attending #IDWeek2025, please mark your calendars 💥
👉 10/20/25: 8-8:25am Dr. Jeremy Walker (UAB) is our invited speaker on “Bridging the Gap between General and TID Practice”, moderated by Drs. Andrea Zimmer and Emily Eichenberger
👉 10/20/25: 8-8:25am Dr. Jeremy Walker (UAB) is our invited speaker on “Bridging the Gap between General and TID Practice”, moderated by Drs. Andrea Zimmer and Emily Eichenberger
Reposted by Steven Pergam, MD, MPH
A study of nearly 300,000 people published today in the New England Journal of Medicine found “that last season’s 2024–2025 mRNA COVID vaccines reduced people’s risk of emergency department visits by 29 percent, their risk of hospitalizations by 39 percent and their risk of death by 64 percent.”
Annual COVID Vaccines Save Lives, New Study Shows
A new study shows that receiving an updated COVID vaccine reduced people’s risk of severe disease and death in all age groups, regardless of immunity from prior infection or vaccination
www.scientificamerican.com
October 8, 2025 at 9:24 PM
A study of nearly 300,000 people published today in the New England Journal of Medicine found “that last season’s 2024–2025 mRNA COVID vaccines reduced people’s risk of emergency department visits by 29 percent, their risk of hospitalizations by 39 percent and their risk of death by 64 percent.”
Don’t become numb to these events
A baby in Mississippi has died of whooping cough for the first time since 2012.
The infant was less than two months old and was not old enough to receive the pertussis vaccine.
buff.ly/8epl2QS
The infant was less than two months old and was not old enough to receive the pertussis vaccine.
buff.ly/8epl2QS
Mississippi Baby Dies of Whooping Cough Amid Rising Cases
A baby in Mississippi has died of whooping cough for the first time since 2012. The baby was less than two months old—too young for vaccination.
www.mississippifreepress.org
September 30, 2025 at 8:05 PM
Don’t become numb to these events
Reposted by Steven Pergam, MD, MPH
Without robust uptake of effective vaccines, children will continue to suffer and die needlessly. A large measles outbreak in Indonesia resulted in 2000 infections and 17 children dying. Mass vaccination campaign now underway.
This was avoidable!
www-pbs-org.cdn.ampproject.org/c/s/www.pbs....
This was avoidable!
www-pbs-org.cdn.ampproject.org/c/s/www.pbs....
After 17 die in measles outbreak, Indonesia launches vaccination campaign
Indonesian authorities have rolled out a vaccination campaign in response to an outbreak that has caused 17 deaths.
www-pbs-org.cdn.ampproject.org
September 29, 2025 at 11:09 PM
Without robust uptake of effective vaccines, children will continue to suffer and die needlessly. A large measles outbreak in Indonesia resulted in 2000 infections and 17 children dying. Mass vaccination campaign now underway.
This was avoidable!
www-pbs-org.cdn.ampproject.org/c/s/www.pbs....
This was avoidable!
www-pbs-org.cdn.ampproject.org/c/s/www.pbs....
Important update that CMV still is the Troll of transplantation
Cytomegalovirus Viral Load Continues to Predict Poor Outcomes in Adults and Children Despite Improved Hematopoietic Cell Transplantation Success url: academic.oup.com/ofid/article...
Cytomegalovirus Viral Load Continues to Predict Poor Outcomes in Adults and Children Despite Improved Hematopoietic Cell Transplantation Success url: academic.oup.com/ofid/article...
Cytomegalovirus Viral Load Continues to Predict Poor Outcomes in Adults and Children Despite Improved Hematopoietic Cell Transplantation Success
AbstractBackground. Recent advances of graft-versus-host disease prevention strategies have led to improved overall survival after hematopoietic cell trans
academic.oup.com
September 29, 2025 at 5:51 PM
Important update that CMV still is the Troll of transplantation
Cytomegalovirus Viral Load Continues to Predict Poor Outcomes in Adults and Children Despite Improved Hematopoietic Cell Transplantation Success url: academic.oup.com/ofid/article...
Cytomegalovirus Viral Load Continues to Predict Poor Outcomes in Adults and Children Despite Improved Hematopoietic Cell Transplantation Success url: academic.oup.com/ofid/article...