Akane
@hoyako.bsky.social
Reposted by Akane
Check out this exciting work by Tim from @jamesmonaghan.bsky.social lab on the gene circuit of RA during limb regeneration www.nature.com/articles/s41...
Retinoic acid breakdown is required for proximodistal positional identity during axolotl limb regeneration - Nature Communications
How axolotl salamanders know what portion of the limb to regenerate remains a mystery. In this article, the authors show that precise retinoic acid degradation is critical for instructing regener...
www.nature.com
June 10, 2025 at 1:57 PM
Check out this exciting work by Tim from @jamesmonaghan.bsky.social lab on the gene circuit of RA during limb regeneration www.nature.com/articles/s41...
Reposted by Akane
Nature research paper: Molecular basis of positional memory in limb regeneration
https://go.nature.com/44OtQj3
https://go.nature.com/44OtQj3
Molecular basis of positional memory in limb regeneration - Nature
A molecular analysis of axolotl limb regeneration has identified a positive genetic circuit that maintains posterior cell identity and can be used to reprogramme anterior cells into posterior cells.
go.nature.com
May 22, 2025 at 2:56 PM
Nature research paper: Molecular basis of positional memory in limb regeneration
https://go.nature.com/44OtQj3
https://go.nature.com/44OtQj3
Reposted by Akane
April 28, 2025 at 9:24 PM
Reposted by Akane
Reposted by Akane
Excited to announce that MBI-MPG Conference 2025: Mechanobiology in Time and Space.
Dates: 9-12 Sep 2025
Venue: Shaw Foundation Alumni House, NUS, Singapore
Website: www.mbi.nus.edu.sg/events/mbico...
The deadline for early bird registration is May 31, 2025
Join us!
Dates: 9-12 Sep 2025
Venue: Shaw Foundation Alumni House, NUS, Singapore
Website: www.mbi.nus.edu.sg/events/mbico...
The deadline for early bird registration is May 31, 2025
Join us!
April 16, 2025 at 2:29 PM
Excited to announce that MBI-MPG Conference 2025: Mechanobiology in Time and Space.
Dates: 9-12 Sep 2025
Venue: Shaw Foundation Alumni House, NUS, Singapore
Website: www.mbi.nus.edu.sg/events/mbico...
The deadline for early bird registration is May 31, 2025
Join us!
Dates: 9-12 Sep 2025
Venue: Shaw Foundation Alumni House, NUS, Singapore
Website: www.mbi.nus.edu.sg/events/mbico...
The deadline for early bird registration is May 31, 2025
Join us!
Reposted by Akane
My favorite examples are the new composite PROX-HOX2 and GLI-RFX3 motifs, which drive highly specific reporter expression in transgenic mouse embryos, with the latter reminiscent of Shh expression pattern!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
April 9, 2025 at 4:52 PM
My favorite examples are the new composite PROX-HOX2 and GLI-RFX3 motifs, which drive highly specific reporter expression in transgenic mouse embryos, with the latter reminiscent of Shh expression pattern!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Akane
Reprogramming site-specific retrotransposon activity to new DNA sites @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
April 9, 2025 at 4:41 PM
Reprogramming site-specific retrotransposon activity to new DNA sites @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Akane
Thrilled to announce that I have just started my own lab at Ritsumeikan Univ (Shiga, Japan) as an Associate Professor! Please contact me if you are interested in working on archaeal 3D genomes in our group!
April 4, 2025 at 7:19 AM
Thrilled to announce that I have just started my own lab at Ritsumeikan Univ (Shiga, Japan) as an Associate Professor! Please contact me if you are interested in working on archaeal 3D genomes in our group!
Reposted by Akane
Our new paper is out@ScienceAdvances👇
www.science.org/doi/10.1126/...
🧬Our Repli-Histo labeling marks nucleosomes in euchromatin and heterochromatin in live human cells.
🔍 @katsuminami.bsky.social et al. have developed a chromatin behavior atlas within the nucleus. 1/2
www.science.org/doi/10.1126/...
🧬Our Repli-Histo labeling marks nucleosomes in euchromatin and heterochromatin in live human cells.
🔍 @katsuminami.bsky.social et al. have developed a chromatin behavior atlas within the nucleus. 1/2
March 29, 2025 at 1:06 AM
Our new paper is out@ScienceAdvances👇
www.science.org/doi/10.1126/...
🧬Our Repli-Histo labeling marks nucleosomes in euchromatin and heterochromatin in live human cells.
🔍 @katsuminami.bsky.social et al. have developed a chromatin behavior atlas within the nucleus. 1/2
www.science.org/doi/10.1126/...
🧬Our Repli-Histo labeling marks nucleosomes in euchromatin and heterochromatin in live human cells.
🔍 @katsuminami.bsky.social et al. have developed a chromatin behavior atlas within the nucleus. 1/2
Reposted by Akane
HighPlay：Cyclic Peptide Sequence Design Based on Reinforcement Learning and Protein Structure Prediction https://www.biorxiv.org/content/10.1101/2025.03.17.643626v1
March 18, 2025 at 5:48 AM
HighPlay：Cyclic Peptide Sequence Design Based on Reinforcement Learning and Protein Structure Prediction https://www.biorxiv.org/content/10.1101/2025.03.17.643626v1
Reposted by Akane
Ultra-fast and highly sensitive protein structure alignment with segment-level representations and block-sparse optimization https://www.biorxiv.org/content/10.1101/2025.03.14.643159v1
March 16, 2025 at 10:45 AM
Ultra-fast and highly sensitive protein structure alignment with segment-level representations and block-sparse optimization https://www.biorxiv.org/content/10.1101/2025.03.14.643159v1
テレビってなんなんだろうか。久々にテレビみてるけど、正しくない情報で視聴者を制御する感すごいな。日本も内的な情報統制がすごい
February 22, 2025 at 11:05 AM
テレビってなんなんだろうか。久々にテレビみてるけど、正しくない情報で視聴者を制御する感すごいな。日本も内的な情報統制がすごい
Reposted by Akane
When your co-organiser/friend publish cool papers! Special shout out and congrats to @jxhoffman.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
RNA polymerase II coordinates histone deacetylation at active promoters
Transcription initiation limits histone acetylation and H2AZ incorporation at promoters.
www.science.org
February 5, 2025 at 8:48 PM
When your co-organiser/friend publish cool papers! Special shout out and congrats to @jxhoffman.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Akane
New online! Epigenetic ageing clocks: statistical methods and emerging computational challenges
Epigenetic ageing clocks: statistical methods and emerging computational challenges
Nature Reviews Genetics, Published online: 13 January 2025; doi:10.1038/s41576-024-00807-wEpigenetic clocks based on DNA methylation data are machine learning tools used to estimate chronological and biological age. The authors review computational and…
go.nature.com
January 13, 2025 at 3:01 PM
New online! Epigenetic ageing clocks: statistical methods and emerging computational challenges
Reposted by Akane
I absolutely love this teeny little transmitter that allowed researchers to figure out that bats surf storm fronts. That story and more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪
January 4, 2025 at 12:31 AM
I absolutely love this teeny little transmitter that allowed researchers to figure out that bats surf storm fronts. That story and more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪
Reposted by Akane
December 24, 2024 at 12:04 PM
December 24, 2024 at 12:04 PM
Reposted by Akane
As you might guess I spend a lot of time thinking about tail regeneration. So I figured we might as well put this in a review article. Glad to see this out before the end of the year and thankful for the input from @murawalalab.bsky.social www.sciencedirect.com/science/arti...
The evolutionary origin and mechanism of chordate tail regeneration. An ancient tale?
Chordate tail regeneration represents the remarkable ability of some chordates to partially or completely regenerate a significant portion of their pr…
www.sciencedirect.com
December 20, 2024 at 9:23 PM
As you might guess I spend a lot of time thinking about tail regeneration. So I figured we might as well put this in a review article. Glad to see this out before the end of the year and thankful for the input from @murawalalab.bsky.social www.sciencedirect.com/science/arti...
世界は平和
ひよこダンゴみせてもろた
Genome edited ヒヨコやったりするねんけど
ひよこダンゴみせてもろた
Genome edited ヒヨコやったりするねんけど
December 18, 2024 at 11:05 AM
世界は平和
ひよこダンゴみせてもろた
Genome edited ヒヨコやったりするねんけど
ひよこダンゴみせてもろた
Genome edited ヒヨコやったりするねんけど
