GlyCosmos
@glycosmos.bsky.social
An official account for GlyCosmos Portal.
The GlyCosmos Portal is a Web portal aiming to integrate the glycosciences with the life sciences. It consists of Standards, Repositories and Data Resources, providing information about genes, proteins, etc.
The GlyCosmos Portal is a Web portal aiming to integrate the glycosciences with the life sciences. It consists of Standards, Repositories and Data Resources, providing information about genes, proteins, etc.
Pinned
GlyCosmos
@glycosmos.bsky.social
· Nov 19
Bridging glycoinformatics and cheminformatics: integration efforts between GlyCosmos and PubChem
Abstract. The GlyCosmos Glycoscience Portal (https://glycosmos.org) and PubChem (https://pubchem.ncbi.nlm.nih.gov/) are major portals for glycoscience and
academic.oup.com
🧬GlyCosmos 🧬
Bridging glycoinformatics and cheminformatics: integration efforts between GlyCosmos and PubChem
academic.oup.com/glycob/artic...
Bridging glycoinformatics and cheminformatics: integration efforts between GlyCosmos and PubChem
academic.oup.com/glycob/artic...
Reposted by GlyCosmos
This is huge news!
UBC has developed an enzyme that can convert donor organs to type O, making them universal.
Normally a using organs of the wrong blood type causes the recipient's immune system to attack the organ, leading to failure.
❤️🇨🇦⚕️
news.ubc.ca/2025/10/univ...
UBC has developed an enzyme that can convert donor organs to type O, making them universal.
Normally a using organs of the wrong blood type causes the recipient's immune system to attack the organ, leading to failure.
❤️🇨🇦⚕️
news.ubc.ca/2025/10/univ...
UBC enzyme technology clears first human test toward universal donor organs for transplantation - UBC News
UBC-developed enzymes successfully converted a kidney to universal type O for transplant, marking a major step toward faster, more compatible organ donations.
news.ubc.ca
October 15, 2025 at 3:54 AM
[LM-GlycomeAtlas]
Building on the LM-GlycoRepo release, the LM-GlycomeAtlas now enables interactive exploration of tissue glycome mapping data in #GlyCosmos.
glycosmos.org/lmglycomeatlas
Building on the LM-GlycoRepo release, the LM-GlycomeAtlas now enables interactive exploration of tissue glycome mapping data in #GlyCosmos.
glycosmos.org/lmglycomeatlas
October 14, 2025 at 2:59 AM
[LM-GlycomeAtlas]
Building on the LM-GlycoRepo release, the LM-GlycomeAtlas now enables interactive exploration of tissue glycome mapping data in #GlyCosmos.
glycosmos.org/lmglycomeatlas
Building on the LM-GlycoRepo release, the LM-GlycomeAtlas now enables interactive exploration of tissue glycome mapping data in #GlyCosmos.
glycosmos.org/lmglycomeatlas
Reposted by GlyCosmos
Have we made it to the point where we can sneak in Pokémon names as method acronyms, relatively undetected?
Protocol for label-free ribosome-associated protein enrichment from mammalian cells by RAPIDASH www.sciencedirect.co...
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#proteomics #prot-paper
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#proteomics #prot-paper
September 4, 2025 at 2:39 PM
Have we made it to the point where we can sneak in Pokémon names as method acronyms, relatively undetected?
Reposted by GlyCosmos
New work from @xingulab.bsky.social @sshaolab.bsky.social & Elledge lab report structure of Midnolin-proteasome complex & its role in controlling myeloma via ubiquitin-independent degradation. www.cell.com/molecular-ce...
Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma
Nardone et al. elucidate the mechanism of the midnolin-proteasome pathway, showing
how midnolin achieves nuclear substrate selection and how established proteasomal
components are repurposed to enable...
www.cell.com
June 21, 2025 at 9:06 PM
New work from @xingulab.bsky.social @sshaolab.bsky.social & Elledge lab report structure of Midnolin-proteasome complex & its role in controlling myeloma via ubiquitin-independent degradation. www.cell.com/molecular-ce...
Reposted by GlyCosmos
An exciting #glycotime meeting planned covering anything glycan ranging from carbohydrate chemistry, analytics, immunology to informatics with speakers from around the world!
🚨Abstract submissions and Travel Award applications to SFG's 2025 World Glyco Expo Annual Meeting 🎉
You must register for the conference prior to submitting your abstract! Deadline July 11th at 11:59 PM (ET), don’t miss the early bird rates! Details ⬇️
www.glycobiology.org/2025-annual-...
You must register for the conference prior to submitting your abstract! Deadline July 11th at 11:59 PM (ET), don’t miss the early bird rates! Details ⬇️
www.glycobiology.org/2025-annual-...
June 27, 2025 at 12:29 AM
An exciting #glycotime meeting planned covering anything glycan ranging from carbohydrate chemistry, analytics, immunology to informatics with speakers from around the world!
Reposted by GlyCosmos
Thank you to the scientists and staff at NIH/NCATS for spending the day showing me your impressive facilities for translational science and drug development. Bringing hope to patients with unmet need 🙏 🇺🇸
June 12, 2025 at 10:06 PM
Thank you to the scientists and staff at NIH/NCATS for spending the day showing me your impressive facilities for translational science and drug development. Bringing hope to patients with unmet need 🙏 🇺🇸
Reposted by GlyCosmos
glycowork v1.6 is out & we're now at 1,000 commits in almost 4 years! Next to Universal Input and a better GlycoDraw, we have a faster back-end, bigger&better datasets, more convenience, and so much more
github.com/BojarLab/gly...
github.com/BojarLab/gly...
May 27, 2025 at 10:55 AM
glycowork v1.6 is out & we're now at 1,000 commits in almost 4 years! Next to Universal Input and a better GlycoDraw, we have a faster back-end, bigger&better datasets, more convenience, and so much more
github.com/BojarLab/gly...
github.com/BojarLab/gly...
[Update] LM-GlycoRepo repository
The GlyCosmos Portal has released a novel "LM-GlycoRepo" repository for lectin-assisted multimodal (LM) data, including lectin microarrays. Version. 1.0 is introduced in a recently published article in the Journal of Proteome Research: doi.org/10.1021/acs....
The GlyCosmos Portal has released a novel "LM-GlycoRepo" repository for lectin-assisted multimodal (LM) data, including lectin microarrays. Version. 1.0 is introduced in a recently published article in the Journal of Proteome Research: doi.org/10.1021/acs....
LM-GlycoRepo Version 1.0: A Novel Repository System for Mouse Tissue Glycome Mapping Data
Lectin microarray (LMA) is a high-sensitive profiling method of protein glycosylation. The increasing use of this method in many studies has led to a growing demand for a repository system that meets ...
doi.org
June 12, 2025 at 8:14 AM
[Update] LM-GlycoRepo repository
The GlyCosmos Portal has released a novel "LM-GlycoRepo" repository for lectin-assisted multimodal (LM) data, including lectin microarrays. Version. 1.0 is introduced in a recently published article in the Journal of Proteome Research: doi.org/10.1021/acs....
The GlyCosmos Portal has released a novel "LM-GlycoRepo" repository for lectin-assisted multimodal (LM) data, including lectin microarrays. Version. 1.0 is introduced in a recently published article in the Journal of Proteome Research: doi.org/10.1021/acs....
Reposted by GlyCosmos
A few GlycoDraw-related highlights of the upcoming glycowork v1.6 update (dropping in a few weeks):
- our very own rendering engine (GlycoDraw for the masses, thanks to glycorender!);
- SNFG-gradients;
- automated Alt text;
- reverse-highlighting;
- even more support for highly complex sequences
- our very own rendering engine (GlycoDraw for the masses, thanks to glycorender!);
- SNFG-gradients;
- automated Alt text;
- reverse-highlighting;
- even more support for highly complex sequences
May 12, 2025 at 8:23 AM
A few GlycoDraw-related highlights of the upcoming glycowork v1.6 update (dropping in a few weeks):
- our very own rendering engine (GlycoDraw for the masses, thanks to glycorender!);
- SNFG-gradients;
- automated Alt text;
- reverse-highlighting;
- even more support for highly complex sequences
- our very own rendering engine (GlycoDraw for the masses, thanks to glycorender!);
- SNFG-gradients;
- automated Alt text;
- reverse-highlighting;
- even more support for highly complex sequences
Reposted by GlyCosmos
Nice #glycotime review that pulls together the emerging story of glycosyltransferase specificity for cellular substrates
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Glycoproteins, Glycolipids, or Both: Why do Glycosyltransferases Recognize Different Acceptors?
Glycosylation is an important post-translational modification catalyzed by glycosyltransferases (GTs), which comprise a large group of enzymes with diversified specificity. Most GTs show high specifi...
chemistry-europe.onlinelibrary.wiley.com
May 7, 2025 at 11:42 AM
Nice #glycotime review that pulls together the emerging story of glycosyltransferase specificity for cellular substrates
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
🌲GlyGen
GlyGen is a global initiative funded by NIH and NIGMS to support glycoscience research by integrating diverse data from glycomics, genomics, proteomics, and biochemistry. It unifies information from multiple international sources into a single platform.
glygen.org/home/
GlyGen is a global initiative funded by NIH and NIGMS to support glycoscience research by integrating diverse data from glycomics, genomics, proteomics, and biochemistry. It unifies information from multiple international sources into a single platform.
glygen.org/home/
May 23, 2025 at 8:21 AM
🌲GlyGen
GlyGen is a global initiative funded by NIH and NIGMS to support glycoscience research by integrating diverse data from glycomics, genomics, proteomics, and biochemistry. It unifies information from multiple international sources into a single platform.
glygen.org/home/
GlyGen is a global initiative funded by NIH and NIGMS to support glycoscience research by integrating diverse data from glycomics, genomics, proteomics, and biochemistry. It unifies information from multiple international sources into a single platform.
glygen.org/home/
🐝 GlyCounter
An intuitive platform designed for seamless integration into glycoproteomic workflows, enabling users to enhance sample and data preparation, and post-acquisition identification by simply evaluating the glycan content within glycoproteomic datasets.
www.biorxiv.org/content/10.1...
An intuitive platform designed for seamless integration into glycoproteomic workflows, enabling users to enhance sample and data preparation, and post-acquisition identification by simply evaluating the glycan content within glycoproteomic datasets.
www.biorxiv.org/content/10.1...
Extracting informative glycan-specific ions from glycopeptide MS/MS spectra with GlyCounter
Glycopeptide tandem mass spectra typically contain numerous glycan-specific fragments that can inform several features of glycan modifications, including glycan class, composition, and structure. Whil...
www.biorxiv.org
March 26, 2025 at 6:52 AM
🐝 GlyCounter
An intuitive platform designed for seamless integration into glycoproteomic workflows, enabling users to enhance sample and data preparation, and post-acquisition identification by simply evaluating the glycan content within glycoproteomic datasets.
www.biorxiv.org/content/10.1...
An intuitive platform designed for seamless integration into glycoproteomic workflows, enabling users to enhance sample and data preparation, and post-acquisition identification by simply evaluating the glycan content within glycoproteomic datasets.
www.biorxiv.org/content/10.1...
Reposted by GlyCosmos
The NCI grant supporting the Columbia comprehensive cancer center was terminated. Tell me how terminating support for cancer research helps the economy.
taggs.hhs.gov/Content/Data...
taggs.hhs.gov/Content/Data...
March 18, 2025 at 10:28 PM
The NCI grant supporting the Columbia comprehensive cancer center was terminated. Tell me how terminating support for cancer research helps the economy.
taggs.hhs.gov/Content/Data...
taggs.hhs.gov/Content/Data...
Reposted by GlyCosmos
Thousands joined this year’s SHE (Stanford Health Empowerment) Talks—online and in person—for an essential convo on brain health w/ Karen Adams, MD, and Sharon Sha, MD. They shared real steps women can take to support brain function for years to come.
youtu.be/BwtKYocLrgo?...
youtu.be/BwtKYocLrgo?...
SHE Talks 2025: Secrets to Brain Vitality
YouTube video by Stanford Medicine
youtu.be
March 18, 2025 at 11:39 PM
Thousands joined this year’s SHE (Stanford Health Empowerment) Talks—online and in person—for an essential convo on brain health w/ Karen Adams, MD, and Sharon Sha, MD. They shared real steps women can take to support brain function for years to come.
youtu.be/BwtKYocLrgo?...
youtu.be/BwtKYocLrgo?...
Reposted by GlyCosmos
Discover how mass spectrometry is revolutionizing vaccine development and infectious disease research! Watch Dr. John Cipollo's insightful GlyGen Webinar now: youtu.be/-5e8MaD8yKI
Don't forget to follow and subscribe for more cutting-edge science content! 🔔
#FDA #glycotime
Don't forget to follow and subscribe for more cutting-edge science content! 🔔
#FDA #glycotime
John Cipollo - Mass Spectrometry Driven Glycoconjugate Analysis
YouTube video by GlyGen myGlyGen
youtu.be
December 18, 2024 at 5:10 AM
Discover how mass spectrometry is revolutionizing vaccine development and infectious disease research! Watch Dr. John Cipollo's insightful GlyGen Webinar now: youtu.be/-5e8MaD8yKI
Don't forget to follow and subscribe for more cutting-edge science content! 🔔
#FDA #glycotime
Don't forget to follow and subscribe for more cutting-edge science content! 🔔
#FDA #glycotime
Reposted by GlyCosmos
🚨 Hiring – Chaire Professeur Junior (CPJ) in Carbohydrate Chemistry! 🚨
ICBMS (Lyon, France) seeks a tenure-track researcher in oligosaccharide & glycoconjugate synthesis.
Learn more: canadianglycomics.ca/training/opp...
ICBMS (Lyon, France) seeks a tenure-track researcher in oligosaccharide & glycoconjugate synthesis.
Learn more: canadianglycomics.ca/training/opp...
Opportunities - Canadian Glycomics Network
Linkedin-in Twitter Facebook-f Instagram Youtube Envelope Main Menu About About GlycoNet People Administration Corporate Policies Governance Board of Directors Executive Committee Finance, Audit & Ris...
canadianglycomics.ca
February 6, 2025 at 7:42 PM
🚨 Hiring – Chaire Professeur Junior (CPJ) in Carbohydrate Chemistry! 🚨
ICBMS (Lyon, France) seeks a tenure-track researcher in oligosaccharide & glycoconjugate synthesis.
Learn more: canadianglycomics.ca/training/opp...
ICBMS (Lyon, France) seeks a tenure-track researcher in oligosaccharide & glycoconjugate synthesis.
Learn more: canadianglycomics.ca/training/opp...
🌹GlyCosmos Youtube Channel
Not sure how to use the GlyCosmos tools? No worries! We’ve provided tutorial videos to guide you through the process. Check them out and get started! #Glycan #Database
www.youtube.com/@glycosmosch...
Not sure how to use the GlyCosmos tools? No worries! We’ve provided tutorial videos to guide you through the process. Check them out and get started! #Glycan #Database
www.youtube.com/@glycosmosch...
GlyCosmos
www.youtube.com
February 4, 2025 at 2:22 AM
🌹GlyCosmos Youtube Channel
Not sure how to use the GlyCosmos tools? No worries! We’ve provided tutorial videos to guide you through the process. Check them out and get started! #Glycan #Database
www.youtube.com/@glycosmosch...
Not sure how to use the GlyCosmos tools? No worries! We’ve provided tutorial videos to guide you through the process. Check them out and get started! #Glycan #Database
www.youtube.com/@glycosmosch...
Reposted by GlyCosmos
Discovery of two novel Flavobacterium species with potential for complex polysaccharide degradation www.nature.com/articles/s41...
Discovery of two novel Flavobacterium species with potential for complex polysaccharide degradation - Scientific Reports
Scientific Reports - Discovery of two novel Flavobacterium species with potential for complex polysaccharide degradation
www.nature.com
January 28, 2025 at 10:53 AM
Discovery of two novel Flavobacterium species with potential for complex polysaccharide degradation www.nature.com/articles/s41...
Reposted by GlyCosmos
Structure of WzxE the lipid III flippase for Enterobacterial Common Antigen polysaccharide. Check this #membrane #protein in the UniTmp database: https://pdbtm.unitmp.org/entry/9g95
royalsocietypublishing.org
February 1, 2025 at 7:56 PM
Structure of WzxE the lipid III flippase for Enterobacterial Common Antigen polysaccharide. Check this #membrane #protein in the UniTmp database: https://pdbtm.unitmp.org/entry/9g95
🛰️ Materials Project
The Materials Project computes the properties of all inorganic materials and provides the data, along with analysis algorithms, freely to materials researchers. It serves as an excellent resource for materials design. #database #BerkeleyLab
next-gen.materialsproject.org
The Materials Project computes the properties of all inorganic materials and provides the data, along with analysis algorithms, freely to materials researchers. It serves as an excellent resource for materials design. #database #BerkeleyLab
next-gen.materialsproject.org
January 30, 2025 at 4:51 AM
🛰️ Materials Project
The Materials Project computes the properties of all inorganic materials and provides the data, along with analysis algorithms, freely to materials researchers. It serves as an excellent resource for materials design. #database #BerkeleyLab
next-gen.materialsproject.org
The Materials Project computes the properties of all inorganic materials and provides the data, along with analysis algorithms, freely to materials researchers. It serves as an excellent resource for materials design. #database #BerkeleyLab
next-gen.materialsproject.org
🦠ChEMBL
Are you looking for data on bioactive molecules with drug-like properties? ChEMBL brings together chemical, bioactivity, and genomic data to aid the translation of genomic information into effective new drugs. #database
www.ebi.ac.uk/chembl/
Are you looking for data on bioactive molecules with drug-like properties? ChEMBL brings together chemical, bioactivity, and genomic data to aid the translation of genomic information into effective new drugs. #database
www.ebi.ac.uk/chembl/
ChEMBL - ChEMBL
www.ebi.ac.uk
January 30, 2025 at 2:30 AM
🦠ChEMBL
Are you looking for data on bioactive molecules with drug-like properties? ChEMBL brings together chemical, bioactivity, and genomic data to aid the translation of genomic information into effective new drugs. #database
www.ebi.ac.uk/chembl/
Are you looking for data on bioactive molecules with drug-like properties? ChEMBL brings together chemical, bioactivity, and genomic data to aid the translation of genomic information into effective new drugs. #database
www.ebi.ac.uk/chembl/
This research presents a framework that guarantees statistical reliability based on user-defined risk and delivers calibrated probabilities instead of raw ML scores for any protein search model. More details 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Functional protein mining with conformal guarantees - Nature Communications
This study presents a protein search framework with conformal prediction, enabling statistically reliable annotation of protein function. The method improves homology search, enzyme classification, an...
www.nature.com
January 30, 2025 at 1:56 AM
This research presents a framework that guarantees statistical reliability based on user-defined risk and delivers calibrated probabilities instead of raw ML scores for any protein search model. More details 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by GlyCosmos
With a new $1.25 million gift from @rsrt.bsky.social to @jenniferdoudna.bsky.social & @doudna-lab.bsky.social postdoc Kai Chen, IGI is developing lipid nanoparticles for editing the brain to treat Rett syndrome & other brain disorders. Read more: ow.ly/PVSy50UACMH
🧬 🧠
🧬 🧠
IGI is Awarded New Funding to Develop CRISPR Tools for Editing the Brain
A new project co-led by IGI founder Jennifer Doudna and Doudna lab researcher Kai Chen has been awarded $1.25 million from the Rett Syndrome Research Trust (RSRT) to develop CRISPR genome-editing tool...
innovativegenomics.org
January 6, 2025 at 8:04 PM
With a new $1.25 million gift from @rsrt.bsky.social to @jenniferdoudna.bsky.social & @doudna-lab.bsky.social postdoc Kai Chen, IGI is developing lipid nanoparticles for editing the brain to treat Rett syndrome & other brain disorders. Read more: ow.ly/PVSy50UACMH
🧬 🧠
🧬 🧠
🌲 IMEx - The International Molecular Consortium
IMEx is a database providing physical molecular interaction data from a broad taxonomic range of organisms. You can find detailed protein-protein/protein-glycan interaction data curated from publications. #protein #glycan
imexconsortium.org
IMEx is a database providing physical molecular interaction data from a broad taxonomic range of organisms. You can find detailed protein-protein/protein-glycan interaction data curated from publications. #protein #glycan
imexconsortium.org
imexconsortium.org
January 24, 2025 at 3:12 AM
🌲 IMEx - The International Molecular Consortium
IMEx is a database providing physical molecular interaction data from a broad taxonomic range of organisms. You can find detailed protein-protein/protein-glycan interaction data curated from publications. #protein #glycan
imexconsortium.org
IMEx is a database providing physical molecular interaction data from a broad taxonomic range of organisms. You can find detailed protein-protein/protein-glycan interaction data curated from publications. #protein #glycan
imexconsortium.org
🪲UniLectin🪲
UniLectin is a specialized database focused on lectins that play critical roles in various biological processes. The platform offers detailed information on lectin sequences, structures, carbohydrate-binding specificities, and biological functions.
pubmed.ncbi.nlm.nih.gov/37889052/
UniLectin is a specialized database focused on lectins that play critical roles in various biological processes. The platform offers detailed information on lectin sequences, structures, carbohydrate-binding specificities, and biological functions.
pubmed.ncbi.nlm.nih.gov/37889052/
HumanLectome, an update of UniLectin for the annotation and prediction of human lectins - PubMed
The UniLectin portal (https://unilectin.unige.ch/) was designed in 2019 with the goal of centralising curated and predicted data on carbohydrate-binding proteins known as lectins. UniLectin is also in...
pubmed.ncbi.nlm.nih.gov
January 18, 2025 at 2:59 AM
🪲UniLectin🪲
UniLectin is a specialized database focused on lectins that play critical roles in various biological processes. The platform offers detailed information on lectin sequences, structures, carbohydrate-binding specificities, and biological functions.
pubmed.ncbi.nlm.nih.gov/37889052/
UniLectin is a specialized database focused on lectins that play critical roles in various biological processes. The platform offers detailed information on lectin sequences, structures, carbohydrate-binding specificities, and biological functions.
pubmed.ncbi.nlm.nih.gov/37889052/