Gary Morris
@gazz4science.bsky.social
Glial-vasculature interactions, pericytes & microglia, dementia & stroke at the University of Tasmania.
Reposted by Gary Morris
🚨 Review Alert
*Walking on the tightrope: the shared roles of the bridging pericytes in the brain*
Congratulations Audrey Chagnot!! 🥳
Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊
www.frontiersin.org/journals/cel...
*Walking on the tightrope: the shared roles of the bridging pericytes in the brain*
Congratulations Audrey Chagnot!! 🥳
Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊
www.frontiersin.org/journals/cel...
Frontiers | Walking on the tightrope: the shared roles of the bridging pericytes in the brain
The vasculature of the central nervous system (CNS) is a highly specialized structure that delivers oxygen and nutrients to energy-demanding neural cells whi...
www.frontiersin.org
July 22, 2025 at 6:48 AM
🚨 Review Alert
*Walking on the tightrope: the shared roles of the bridging pericytes in the brain*
Congratulations Audrey Chagnot!! 🥳
Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊
www.frontiersin.org/journals/cel...
*Walking on the tightrope: the shared roles of the bridging pericytes in the brain*
Congratulations Audrey Chagnot!! 🥳
Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊
www.frontiersin.org/journals/cel...
Reposted by Gary Morris
Microglial control of cerebral capillary basal tone. Congrats to @eyolab.bsky.social & team ! #cerebrovascular
Microglial cyclooxygenase-1 modulates cerebral capillary basal tone in vivo in mice - Nature Communications
The role of myeloid cells in vascular regulation remains incompletely understood. Here, the authors show that microglia are the only myeloid cells that localize to capillaries and that they maintain b...
www.nature.com
July 4, 2025 at 4:05 PM
Microglial control of cerebral capillary basal tone. Congrats to @eyolab.bsky.social & team ! #cerebrovascular
Reposted by Gary Morris
🐭🧠 #PrecapillarySphincters (PS) at the #arteriole–#capillary junction rapidly dilate ~30% in seconds during #SensoryStimulation—regulating #capillary #BloodFlow dynamically. Here we investigated whether they protect downstream microvessels during abrupt #BloodPressure surges 🧪🧵
June 10, 2025 at 7:38 PM
🐭🧠 #PrecapillarySphincters (PS) at the #arteriole–#capillary junction rapidly dilate ~30% in seconds during #SensoryStimulation—regulating #capillary #BloodFlow dynamically. Here we investigated whether they protect downstream microvessels during abrupt #BloodPressure surges 🧪🧵
Reposted by Gary Morris
New study about the role of microglia in regulating #cerebrovascular function, with an interesting twist on purineric signaling doi.org/10.1038/s414...
Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39 - Nature Communications
Microglia and border-associated macrophages play a role in regulating cerebral blood flow (CBF), but the underlying mechanisms are unclear. Here, the authors show a role for microglial CD39 in the reg...
doi.org
January 27, 2025 at 12:11 PM
New study about the role of microglia in regulating #cerebrovascular function, with an interesting twist on purineric signaling doi.org/10.1038/s414...
Reposted by Gary Morris
Mice lacking microglia (Csf1r∆FIRE/∆FIRE) have normal
-synapse number and maturation
-seizure susceptibility and hippocampal-prefrontal cortex coherence
-segregation of inputs into the lateral geniculate nucleus
-neuronal and astrocytic gene expression
www.nature.com/articles/s41...
-synapse number and maturation
-seizure susceptibility and hippocampal-prefrontal cortex coherence
-segregation of inputs into the lateral geniculate nucleus
-neuronal and astrocytic gene expression
www.nature.com/articles/s41...
Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus - Nature Neuroscience
Microglia are proposed to have a role in brain development through synaptic engulfment and paracrine signaling. O’Keeffe et al. show that certain neurodevelopmental processes attributed to microglia c...
www.nature.com
January 7, 2025 at 2:34 PM
Mice lacking microglia (Csf1r∆FIRE/∆FIRE) have normal
-synapse number and maturation
-seizure susceptibility and hippocampal-prefrontal cortex coherence
-segregation of inputs into the lateral geniculate nucleus
-neuronal and astrocytic gene expression
www.nature.com/articles/s41...
-synapse number and maturation
-seizure susceptibility and hippocampal-prefrontal cortex coherence
-segregation of inputs into the lateral geniculate nucleus
-neuronal and astrocytic gene expression
www.nature.com/articles/s41...
Had a fantastic week at #ANS2024 with Australasian Neuroscience colleagues talking #microglia, #pericytes and #TasmanianDevils. Look forward to seeing you all again in #Hobart for #ANS2025!
December 4, 2024 at 9:37 AM
Had a fantastic week at #ANS2024 with Australasian Neuroscience colleagues talking #microglia, #pericytes and #TasmanianDevils. Look forward to seeing you all again in #Hobart for #ANS2025!
Here's a fun one for #FluorescenceFriday. Did you know #marsupials have an entirely different CNS vascular anatomy to most animals? Arterioles and venules enter the brain and branch in unison, terminating at capillary loops. Check out this example from a #TasmanianDevil brain! (1/2)
November 29, 2024 at 12:43 AM
Here's a fun one for #FluorescenceFriday. Did you know #marsupials have an entirely different CNS vascular anatomy to most animals? Arterioles and venules enter the brain and branch in unison, terminating at capillary loops. Check out this example from a #TasmanianDevil brain! (1/2)
Reposted by Gary Morris
Here we show how #microglia contact #pericytes and #endothelialcells in the #venule end of the #capillary bed. Note also how a #primarycilium of an #interneuron invaginates the microglia. But why? 🤔 journals.sagepub.com/doi/full/10.... @gazz4science.bsky.social
November 26, 2024 at 5:44 PM
Here we show how #microglia contact #pericytes and #endothelialcells in the #venule end of the #capillary bed. Note also how a #primarycilium of an #interneuron invaginates the microglia. But why? 🤔 journals.sagepub.com/doi/full/10.... @gazz4science.bsky.social
Lovely new review to help identify features of microglia in EM images!
I like microglia and I like electron microscopy. Today my new review on microglia ultrastructure came out on Open Biology.
doi.org/10.1098/rsob...
I tried to do a guide I wish I had on my PhD. Thankful for all the people that have taught me microglia EM
#microglia #electronmicroscopy
#tremblaylab
doi.org/10.1098/rsob...
I tried to do a guide I wish I had on my PhD. Thankful for all the people that have taught me microglia EM
#microglia #electronmicroscopy
#tremblaylab
November 21, 2024 at 1:34 AM
Lovely new review to help identify features of microglia in EM images!
Calling all #pericyte researchers!
Here's a list of us to start a community on Bluesky. Please feel free to reply to get added and share with your colleagues as more join!
go.bsky.app/GhVdxzC
Here's a list of us to start a community on Bluesky. Please feel free to reply to get added and share with your colleagues as more join!
go.bsky.app/GhVdxzC
November 19, 2024 at 10:51 PM
Calling all #pericyte researchers!
Here's a list of us to start a community on Bluesky. Please feel free to reply to get added and share with your colleagues as more join!
go.bsky.app/GhVdxzC
Here's a list of us to start a community on Bluesky. Please feel free to reply to get added and share with your colleagues as more join!
go.bsky.app/GhVdxzC
Reposted by Gary Morris
some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
November 17, 2024 at 8:35 PM
some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
Reposted by Gary Morris
Microglia community, let’s start the discussion 🧠 follow the Microglia Starter Pack and ask @mancusorenzo.bsky.social to add your colleagues as they join Bluesky 🦋
go.bsky.app/DT3Cp4A
go.bsky.app/DT3Cp4A
November 17, 2024 at 12:52 PM
Microglia community, let’s start the discussion 🧠 follow the Microglia Starter Pack and ask @mancusorenzo.bsky.social to add your colleagues as they join Bluesky 🦋
go.bsky.app/DT3Cp4A
go.bsky.app/DT3Cp4A
Reposted by Gary Morris
Someone had to do it! I created a starter pack for #Alzheimer’s #dementia #ADRD researchers on Bluesky. Please let me know who I left out! Hoping more and more of us will join Bluesky
go.bsky.app/22DpUEy
go.bsky.app/22DpUEy
November 15, 2024 at 6:18 PM
Someone had to do it! I created a starter pack for #Alzheimer’s #dementia #ADRD researchers on Bluesky. Please let me know who I left out! Hoping more and more of us will join Bluesky
go.bsky.app/22DpUEy
go.bsky.app/22DpUEy
Reposted by Gary Morris
go.bsky.app/Lyzro3M
!WELCOME!
thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list.
apologies for missing many of you - please do reply to get added
and remember to repost so the newbies can find us!
!WELCOME!
thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list.
apologies for missing many of you - please do reply to get added
and remember to repost so the newbies can find us!
November 14, 2024 at 3:21 AM
go.bsky.app/Lyzro3M
!WELCOME!
thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list.
apologies for missing many of you - please do reply to get added
and remember to repost so the newbies can find us!
!WELCOME!
thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list.
apologies for missing many of you - please do reply to get added
and remember to repost so the newbies can find us!