The French DC Society - Club Francophone des DC (CFCD)
@frenchdcsociety.bsky.social
We are mononuclear phagocytes enthusiasts and we organise biennial international meetings on the topic in France...
https://www.cfcd.fr
https://www.cfcd.fr
Pinned
Registration Open for the 2025 French Dendritic Cell Society (CFCD) !!
www.cfcd.fr/meeting/prog...
When: December 4th - 5th, 2025
Where: Institut Curie in Paris
How: 👇👇👇
docs.google.com/forms/d/e/1F...
Deadlines
- October 15th, 2025: Early Birds + Abstracts
- November 15th, 2025: Late abstracts
www.cfcd.fr/meeting/prog...
When: December 4th - 5th, 2025
Where: Institut Curie in Paris
How: 👇👇👇
docs.google.com/forms/d/e/1F...
Deadlines
- October 15th, 2025: Early Birds + Abstracts
- November 15th, 2025: Late abstracts
Fascinating new study from the B. Reizis group in @natimmunol.nature.com
Tonic type I IFN signaling restrains pDC cytokine production & survival — yet makes them tougher against viruses.
👉 A fine-tuned balance for optimal antiviral immunity
www.nature.com/articles/s41...
Tonic type I IFN signaling restrains pDC cytokine production & survival — yet makes them tougher against viruses.
👉 A fine-tuned balance for optimal antiviral immunity
www.nature.com/articles/s41...
Tonic type I interferon signaling optimizes the antiviral function of plasmacytoid dendritic cells - Nature Immunology
Pucella, Maqueda-Alfaro and colleagues distinguish three developmentally related subsets of mouse plasmacytoid dendritic cells that differ in their ability to produce type I interferon and their susce...
www.nature.com
October 20, 2025 at 8:06 AM
Fascinating new study from the B. Reizis group in @natimmunol.nature.com
Tonic type I IFN signaling restrains pDC cytokine production & survival — yet makes them tougher against viruses.
👉 A fine-tuned balance for optimal antiviral immunity
www.nature.com/articles/s41...
Tonic type I IFN signaling restrains pDC cytokine production & survival — yet makes them tougher against viruses.
👉 A fine-tuned balance for optimal antiviral immunity
www.nature.com/articles/s41...
🚨 The early bird registration deadline for the French DC Society meeting has been extended to October 24th, 2025!
Don’t miss the chance — register now!
Registration👇
docs.google.com/forms/d/e/1F...
Program 👇
www.cfcd.fr/meeting/prog...
Don’t miss the chance — register now!
Registration👇
docs.google.com/forms/d/e/1F...
Program 👇
www.cfcd.fr/meeting/prog...
October 15, 2025 at 3:54 PM
🚨 The early bird registration deadline for the French DC Society meeting has been extended to October 24th, 2025!
Don’t miss the chance — register now!
Registration👇
docs.google.com/forms/d/e/1F...
Program 👇
www.cfcd.fr/meeting/prog...
Don’t miss the chance — register now!
Registration👇
docs.google.com/forms/d/e/1F...
Program 👇
www.cfcd.fr/meeting/prog...
Reposted by The French DC Society - Club Francophone des DC (CFCD)
🚨 Postdoc Opportunity – Pathogen-Host Interaction 🚨 (2.5y)
🦠 Join our team to uncover the molecular mechanisms of Y. pestis infection in fleas within a @anrs-mie.bsky.social PEPR-funded project!
🔬 Profile: PhD in microbiology
#Postdoc #Microbiology #YersiniaPestis #ResearchJobs
🦠 Join our team to uncover the molecular mechanisms of Y. pestis infection in fleas within a @anrs-mie.bsky.social PEPR-funded project!
🔬 Profile: PhD in microbiology
#Postdoc #Microbiology #YersiniaPestis #ResearchJobs
October 5, 2025 at 3:08 PM
🚨 Postdoc Opportunity – Pathogen-Host Interaction 🚨 (2.5y)
🦠 Join our team to uncover the molecular mechanisms of Y. pestis infection in fleas within a @anrs-mie.bsky.social PEPR-funded project!
🔬 Profile: PhD in microbiology
#Postdoc #Microbiology #YersiniaPestis #ResearchJobs
🦠 Join our team to uncover the molecular mechanisms of Y. pestis infection in fleas within a @anrs-mie.bsky.social PEPR-funded project!
🔬 Profile: PhD in microbiology
#Postdoc #Microbiology #YersiniaPestis #ResearchJobs
⏰ Only until 15 Oct 2025 to submit your abstract & grab early-bird registration!
Join us in Paris for the French DCs Meeting — featuring an outstanding speaker lineup.
Program 👇
www.cfcd.fr/meeting/prog...
Registration 👇
docs.google.com/forms/d/e/1F...
#DCMeeting2025 #Immunology
Join us in Paris for the French DCs Meeting — featuring an outstanding speaker lineup.
Program 👇
www.cfcd.fr/meeting/prog...
Registration 👇
docs.google.com/forms/d/e/1F...
#DCMeeting2025 #Immunology
October 2, 2025 at 7:30 AM
⏰ Only until 15 Oct 2025 to submit your abstract & grab early-bird registration!
Join us in Paris for the French DCs Meeting — featuring an outstanding speaker lineup.
Program 👇
www.cfcd.fr/meeting/prog...
Registration 👇
docs.google.com/forms/d/e/1F...
#DCMeeting2025 #Immunology
Join us in Paris for the French DCs Meeting — featuring an outstanding speaker lineup.
Program 👇
www.cfcd.fr/meeting/prog...
Registration 👇
docs.google.com/forms/d/e/1F...
#DCMeeting2025 #Immunology
E. Tomasello & team at @ciml.bsky.social challenge the prevailing dogma of plasmacytoid DC's role in anti-viral immunity, by showing that they are deleterious in respiratory viral infections.
CONGRATS 🍾 can't wait to hear more about it the next French DC society meeting👇
www.cfcd.fr/meeting/prog...
CONGRATS 🍾 can't wait to hear more about it the next French DC society meeting👇
www.cfcd.fr/meeting/prog...
Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections - Nature Immunology
Previous research has suggested that pDCs are required for an effective antiviral immune response, but direct experimental evidence to support this is lacking. Here Ngo et al. develop a pDC knockin mouse model and find that pDCs are dispensable for an antiviral immune response to mouse cytomegalovirus and may be detrimental during influenza or SARS-CoV-2 infection.
www.nature.com
October 1, 2025 at 3:58 PM
E. Tomasello & team at @ciml.bsky.social challenge the prevailing dogma of plasmacytoid DC's role in anti-viral immunity, by showing that they are deleterious in respiratory viral infections.
CONGRATS 🍾 can't wait to hear more about it the next French DC society meeting👇
www.cfcd.fr/meeting/prog...
CONGRATS 🍾 can't wait to hear more about it the next French DC society meeting👇
www.cfcd.fr/meeting/prog...
🚨A new study in @elife.bsky.social "reveals crucial roles of cDC1 in atherosclerosis progression and provides insights into the development of therapies by targeting cDC1 through Xcl1"🚨
👇👇
elifesciences.org/articles/107...
👇👇
elifesciences.org/articles/107...
September 18, 2025 at 3:10 PM
🚨A new study in @elife.bsky.social "reveals crucial roles of cDC1 in atherosclerosis progression and provides insights into the development of therapies by targeting cDC1 through Xcl1"🚨
👇👇
elifesciences.org/articles/107...
👇👇
elifesciences.org/articles/107...
The 8th Symposium of the French Network on Monocytes-Macrophages (SoMM2025), will take place in Lyon, France, on November 7th, 2025
📝 Registration (free but mandatory) and abstract submission are now open until October 10th, 2025 : somm2025.sciencesconf.org
Amazing line up
👇👇👇
📝 Registration (free but mandatory) and abstract submission are now open until October 10th, 2025 : somm2025.sciencesconf.org
Amazing line up
👇👇👇
September 12, 2025 at 10:08 AM
The 8th Symposium of the French Network on Monocytes-Macrophages (SoMM2025), will take place in Lyon, France, on November 7th, 2025
📝 Registration (free but mandatory) and abstract submission are now open until October 10th, 2025 : somm2025.sciencesconf.org
Amazing line up
👇👇👇
📝 Registration (free but mandatory) and abstract submission are now open until October 10th, 2025 : somm2025.sciencesconf.org
Amazing line up
👇👇👇
Reposted by The French DC Society - Club Francophone des DC (CFCD)
A targetable epigenetic node of myeloid progenitor dysregulation that sustains immunosuppressive lung tumor microenvironment, a target for improving immunotherapy outcomes @nature.com @miriammerad.bsky.social
@sinaiimmuno.bsky.social
www.nature.com/articles/s41...
@sinaiimmuno.bsky.social
www.nature.com/articles/s41...
September 10, 2025 at 4:55 PM
A targetable epigenetic node of myeloid progenitor dysregulation that sustains immunosuppressive lung tumor microenvironment, a target for improving immunotherapy outcomes @nature.com @miriammerad.bsky.social
@sinaiimmuno.bsky.social
www.nature.com/articles/s41...
@sinaiimmuno.bsky.social
www.nature.com/articles/s41...
Reposted by The French DC Society - Club Francophone des DC (CFCD)
Myeloid cells drive #neuroinflammation in #MultipleSclerosis by promoting immune activation in the #CentralNervousSystem. This study identifies SLAMF5 as a key myeloid receptor that regulates this process, showing that its blockade reduces disease progression @plosbiology.org 🧪 plos.io/3Vb7xhx
September 10, 2025 at 1:03 PM
Myeloid cells drive #neuroinflammation in #MultipleSclerosis by promoting immune activation in the #CentralNervousSystem. This study identifies SLAMF5 as a key myeloid receptor that regulates this process, showing that its blockade reduces disease progression @plosbiology.org 🧪 plos.io/3Vb7xhx
Reposted by The French DC Society - Club Francophone des DC (CFCD)
Congratulations to Carola García de Vinuesa on receiving the 2026 FEBS | EMBO #WomenInScience Award! She is recognized for advancing the understanding of autoimmune diseases and for her impact within the #LifeSciences community, in particular in public engagement: www.embo.org/press-releas... 🧪
FEBS | EMBO Women in Science Award 2026 for Carola García de Vinuesa – Press releases – EMBO
She is recognized for advancing the understanding of autoimmune diseases and bringing science into the public eye
www.embo.org
September 9, 2025 at 12:13 PM
Congratulations to Carola García de Vinuesa on receiving the 2026 FEBS | EMBO #WomenInScience Award! She is recognized for advancing the understanding of autoimmune diseases and for her impact within the #LifeSciences community, in particular in public engagement: www.embo.org/press-releas... 🧪
Exciting work in @scienceimmuno.bsky.social : boosting Dendritic Cells with FLT3L + CD40 agonists reactivates T cell immunity in pancreatic cancer—shown in both mice and patients.
👇
www.science.org/doi/10.1126/...
👇
www.science.org/doi/10.1126/...
Combined Flt3L and CD40 agonism restores dendritic cell–driven T cell immunity in pancreatic cancer
Flt3L and CD40 agonism enhance dendritic cell immunosurveillance in human and murine pancreatic cancer and engage type I immunity.
www.science.org
September 10, 2025 at 9:01 AM
Exciting work in @scienceimmuno.bsky.social : boosting Dendritic Cells with FLT3L + CD40 agonists reactivates T cell immunity in pancreatic cancer—shown in both mice and patients.
👇
www.science.org/doi/10.1126/...
👇
www.science.org/doi/10.1126/...
Reposted by The French DC Society - Club Francophone des DC (CFCD)
Fantastic new story @jkagan1.bsky.social & friends showing that human dendritic cells can become hyperactive activating the inflammasome without dying, & that this approach can be used in mice and NHPs to potentiate anti-influenza vaccine responses! 👇👇👇
An NLRP3 stimulatory universal influenza vaccine.
We report an NLRP3 stimulus that generates hyperactive dendritic cells (hDCs).
journals.asm.org/doi/10.1128/...
We report an NLRP3 stimulus that generates hyperactive dendritic cells (hDCs).
journals.asm.org/doi/10.1128/...
An NLRP3-stimulatory adjuvant improves the immunogenicity of influenza virus vaccines in mice and non-human primates | mBio
The generation of vaccines that stimulate T cell activities is an unmet need for the
scientific community, as T cells are the primary mediators of immune memory. In this
study, we report a new vaccine...
journals.asm.org
September 8, 2025 at 8:30 PM
Fantastic new story @jkagan1.bsky.social & friends showing that human dendritic cells can become hyperactive activating the inflammasome without dying, & that this approach can be used in mice and NHPs to potentiate anti-influenza vaccine responses! 👇👇👇
🚨 New in @natimmunol.nature.com : @idoyagalab.bsky.social shows that plasmacytoid DCs can reprogram into cDC2s after TNF-α stimulation. Fascinating plasticity!
👇
www.nature.com/articles/s41...
👇
www.nature.com/articles/s41...
TNF and type I interferon crosstalk controls the fate and function of plasmacytoid dendritic cells - Nature Immunology
Plasmacytoid dendritic cells are type 1 interferon (IFN-I)-producing antiviral specialists that have been shown to be able to differentiate into conventional dendritic cells. Here the authors show how...
www.nature.com
September 9, 2025 at 8:14 AM
🚨 New in @natimmunol.nature.com : @idoyagalab.bsky.social shows that plasmacytoid DCs can reprogram into cDC2s after TNF-α stimulation. Fascinating plasticity!
👇
www.nature.com/articles/s41...
👇
www.nature.com/articles/s41...
🤯 By spitting out DNASE1L3, Dendritic Cells chew up NETs and make immunotherapy hit harder against tumors.
Cool science in @cp-cancercell.bsky.social 🧬✨
www.cell.com/cancer-cell/...
#Dendritic #Immunology #CancerResearch
Cool science in @cp-cancercell.bsky.social 🧬✨
www.cell.com/cancer-cell/...
#Dendritic #Immunology #CancerResearch
DNASE1L3-expressing dendritic cells promote CD8+ T cell function and anti-PD-(L)1 therapy efficacy by degrading neutrophil extracellular traps
Chen et al. demonstrate that DNASE1L3+ dendritic cells degrade neutrophil extracellular
traps, thereby facilitating CD8+ T cell infiltration, effector function, and cytotoxic
hub formation within the ...
www.cell.com
September 4, 2025 at 2:41 PM
🤯 By spitting out DNASE1L3, Dendritic Cells chew up NETs and make immunotherapy hit harder against tumors.
Cool science in @cp-cancercell.bsky.social 🧬✨
www.cell.com/cancer-cell/...
#Dendritic #Immunology #CancerResearch
Cool science in @cp-cancercell.bsky.social 🧬✨
www.cell.com/cancer-cell/...
#Dendritic #Immunology #CancerResearch
The laboratory of Filipe Pereira @lunduniversity.bsky.social in @cp-immunity.bsky.social "uncover transcriptional circuits that control DC diversification"
Very cool approach and can't wait to hear more about it the next French DC society meeting👇
www.cfcd.fr/meeting/prog...
Very cool approach and can't wait to hear more about it the next French DC society meeting👇
www.cfcd.fr/meeting/prog...
Anchored screening identifies transcription factor blueprints underlying dendritic cell diversity and subset-specific anti-tumor immunity
Transcription factors are known to guide dendritic cell identity, but how they cooperate
to drive lineage diversification remains unclear. Henriques-Oliveira, Altman, Kurochkin,
et al. identify two tr...
www.cell.com
September 3, 2025 at 8:41 AM
The laboratory of Filipe Pereira @lunduniversity.bsky.social in @cp-immunity.bsky.social "uncover transcriptional circuits that control DC diversification"
Very cool approach and can't wait to hear more about it the next French DC society meeting👇
www.cfcd.fr/meeting/prog...
Very cool approach and can't wait to hear more about it the next French DC society meeting👇
www.cfcd.fr/meeting/prog...
🚨 2025 French Dendritic Cell Society (CFCD) Symposium 🚨
Program: www.cfcd.fr/meeting/prog...
When: December 4th - 5th, 2025
Where: Institut Curie in Paris
Register: 👇
docs.google.com/forms/d/e/1F...
Deadlines
- October 15th, 2025: Early Birds + Abstracts
- November 15th, 2025: Late abstracts
Program: www.cfcd.fr/meeting/prog...
When: December 4th - 5th, 2025
Where: Institut Curie in Paris
Register: 👇
docs.google.com/forms/d/e/1F...
Deadlines
- October 15th, 2025: Early Birds + Abstracts
- November 15th, 2025: Late abstracts
September 2, 2025 at 8:54 AM
🚨 2025 French Dendritic Cell Society (CFCD) Symposium 🚨
Program: www.cfcd.fr/meeting/prog...
When: December 4th - 5th, 2025
Where: Institut Curie in Paris
Register: 👇
docs.google.com/forms/d/e/1F...
Deadlines
- October 15th, 2025: Early Birds + Abstracts
- November 15th, 2025: Late abstracts
Program: www.cfcd.fr/meeting/prog...
When: December 4th - 5th, 2025
Where: Institut Curie in Paris
Register: 👇
docs.google.com/forms/d/e/1F...
Deadlines
- October 15th, 2025: Early Birds + Abstracts
- November 15th, 2025: Late abstracts
The group of @florentginhoux.bsky.social "delineate the development of type 2 conventional DCs and plasmacytoid DCs in mice, defining distinct ontogenies and transcription factor dependencies". Bravo the team 🍾 👇https://www.nature.com/articles/s41590-025-02208-5
Transcription factors TCF4 and KLF4 respectively control the development of the DC2A and DC2B lineages - Nature Immunology
Here Zhu et al. investigate the ontogeny of type 2 dendritic cells (DC2s) in mice. Using Klf4 expression to distinguish conventional DC precursors from plasmacytoid DCs, they identify two pre-DC2 popu...
www.nature.com
July 27, 2025 at 4:27 PM
The group of @florentginhoux.bsky.social "delineate the development of type 2 conventional DCs and plasmacytoid DCs in mice, defining distinct ontogenies and transcription factor dependencies". Bravo the team 🍾 👇https://www.nature.com/articles/s41590-025-02208-5
New insights in @nature.com on how microbiota can drive anti-tumor immunity. It appears that CD103+ CD11b- gut cDCs play a central role in the process. Congrats to the Benno. Y and Nishikawa. H labs 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Microbiota-driven antitumour immunity mediated by dendritic cell migration - Nature
A newly identified bacterial strain (YB328) isolated from the faeces of patients who responded to immune checkpoint blockade therapies can promote antitumour immunity through the activation of tumour-...
www.nature.com
July 18, 2025 at 2:09 PM
New insights in @nature.com on how microbiota can drive anti-tumor immunity. It appears that CD103+ CD11b- gut cDCs play a central role in the process. Congrats to the Benno. Y and Nishikawa. H labs 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A short spotlight in @cp-immunity.bsky.social by Brian Kelsall.
on the recently described RORγt+ DCs and their function in inducing intestinal tolerance.
www.sciencedirect.com/science/arti...
on the recently described RORγt+ DCs and their function in inducing intestinal tolerance.
www.sciencedirect.com/science/arti...
RORγt+ dendritic cells and regulatory T cells: A couple hiding in the shadows
The induction of CD4+Foxp3+ regulatory T cells (pTreg cells) in the intestine is important for preventing allergic and inflammatory disease, but which…
www.sciencedirect.com
July 16, 2025 at 9:04 AM
A short spotlight in @cp-immunity.bsky.social by Brian Kelsall.
on the recently described RORγt+ DCs and their function in inducing intestinal tolerance.
www.sciencedirect.com/science/arti...
on the recently described RORγt+ DCs and their function in inducing intestinal tolerance.
www.sciencedirect.com/science/arti...
Congrats to the Henao-Mejia lab for this impressive work in @cp-immunity.bsky.social showing that targeting mitochondrial complex IV in TAMs boosts interferon signalling and ultimately anti-tumor immunity. 👇
www.cell.com/immunity/abs...
www.cell.com/immunity/abs...
Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity
Clark et al. reveal that tumor-derived cues induce a functional switch in tumor-associated
macrophages (TAMs) through decreased expression of NDUFA4, a mitochondrial complex
IV subunit. This promotes ...
www.cell.com
July 7, 2025 at 10:42 AM
Congrats to the Henao-Mejia lab for this impressive work in @cp-immunity.bsky.social showing that targeting mitochondrial complex IV in TAMs boosts interferon signalling and ultimately anti-tumor immunity. 👇
www.cell.com/immunity/abs...
www.cell.com/immunity/abs...
🚨very nice story in @nature.com showing that "disruption of dendritic cells motility in tumors promotes immune evasion, and its enhancement offers a promising direction for DC-centric immunotherapy"🚨. www.nature.com/articles/s41...
Rescuing dendritic cell interstitial motility sustains antitumour immunity - Nature
Disruption of dendritic cell (DC) interstitial motility in the tumour microenvironment promotes immune evasion, and enhancement of DC interstitial motility offers a route for DC-centric immunotherapy.
www.nature.com
June 30, 2025 at 8:18 AM
🚨very nice story in @nature.com showing that "disruption of dendritic cells motility in tumors promotes immune evasion, and its enhancement offers a promising direction for DC-centric immunotherapy"🚨. www.nature.com/articles/s41...
Congrats to the @masslab.bsky.social for this beautiful story in @nature.com showing how the programming of liver resident macrophages, known as Kupffer Cells, by maternal obesity triggers fatty liver disease.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Kupffer cell programming by maternal obesity triggers fatty liver disease - Nature
In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.
www.nature.com
June 25, 2025 at 3:31 PM
Congrats to the @masslab.bsky.social for this beautiful story in @nature.com showing how the programming of liver resident macrophages, known as Kupffer Cells, by maternal obesity triggers fatty liver disease.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
✈️ Travel Grants for Junior Scientists!
The French DC Society (CFCD) is awarding 2 travel grants to support junior researchers attending scientific conferences.
🔗 Application Details: www.cfcd.fr/news/88-trav...
🗓️ Deadline 15th of September 2025.
The French DC Society (CFCD) is awarding 2 travel grants to support junior researchers attending scientific conferences.
🔗 Application Details: www.cfcd.fr/news/88-trav...
🗓️ Deadline 15th of September 2025.
June 23, 2025 at 9:57 AM
✈️ Travel Grants for Junior Scientists!
The French DC Society (CFCD) is awarding 2 travel grants to support junior researchers attending scientific conferences.
🔗 Application Details: www.cfcd.fr/news/88-trav...
🗓️ Deadline 15th of September 2025.
The French DC Society (CFCD) is awarding 2 travel grants to support junior researchers attending scientific conferences.
🔗 Application Details: www.cfcd.fr/news/88-trav...
🗓️ Deadline 15th of September 2025.
🔥🔥2025 Langerhans cells International Workshop🔥🔥
Sept. 3-5 2025 in beautiful Saint Louis, Missouri
All you need to know 👇👇👇
Sept. 3-5 2025 in beautiful Saint Louis, Missouri
All you need to know 👇👇👇
June 19, 2025 at 4:26 PM
🔥🔥2025 Langerhans cells International Workshop🔥🔥
Sept. 3-5 2025 in beautiful Saint Louis, Missouri
All you need to know 👇👇👇
Sept. 3-5 2025 in beautiful Saint Louis, Missouri
All you need to know 👇👇👇
Reposted by The French DC Society - Club Francophone des DC (CFCD)
#LocationLocationLocation! #NewVirusSensingModality! Lahaye, @manellab.bsky.social &co show @cp-cell.bsky.social that nuclear cGAS senses viruses by recognizing centromeric DNA amplification caused by viral effectors that degrade centromere proteins! www.cell.com/cell/abstrac...
Centromeric DNA amplification triggered by viral proteins activates nuclear cGAS
Herpesvirus proteins disrupt centromeres, triggering centromeric DNA amplification
and local nuclear activation of the nucleic acid sensor cGAS. This reveals an immune
surveillance mechanism in the nu...
www.cell.com
June 3, 2025 at 11:26 AM
#LocationLocationLocation! #NewVirusSensingModality! Lahaye, @manellab.bsky.social &co show @cp-cell.bsky.social that nuclear cGAS senses viruses by recognizing centromeric DNA amplification caused by viral effectors that degrade centromere proteins! www.cell.com/cell/abstrac...