Freddy Boutrot
@freddyboutrot.bsky.social
Translational researcher in plant disease resistance
@Limagrain, opinions are my own 🌽🌾🧬🔬
@Limagrain, opinions are my own 🌽🌾🧬🔬
Reposted by Freddy Boutrot
Today is a big day as the Precision Breeding Act comes into force 🌱
@kamounlab.bsky.social: “This is a milestone for UK science and innovation. We now have the regulatory framework to translate discovery into impact — improving crops, strengthening food security, and benefiting society” 🌿
@kamounlab.bsky.social: “This is a milestone for UK science and innovation. We now have the regulatory framework to translate discovery into impact — improving crops, strengthening food security, and benefiting society” 🌿
November 13, 2025 at 5:27 PM
Today is a big day as the Precision Breeding Act comes into force 🌱
@kamounlab.bsky.social: “This is a milestone for UK science and innovation. We now have the regulatory framework to translate discovery into impact — improving crops, strengthening food security, and benefiting society” 🌿
@kamounlab.bsky.social: “This is a milestone for UK science and innovation. We now have the regulatory framework to translate discovery into impact — improving crops, strengthening food security, and benefiting society” 🌿
Reposted by Freddy Boutrot
Enhancing NLR activation by endophytes carrying recognized effectors that are expressed in the presence of ROS. #plantimmunity
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
Genetically engineered plant endophytes broaden effector-triggered immunity
Hou et al. engineer plant endophytes to express effectors that trigger NLR-mediated
ETI upon pathogen infection, regardless of whether pathogens carry recognizable effectors.
The sentinel bacterium ma...
www.cell.com
November 12, 2025 at 4:51 PM
Enhancing NLR activation by endophytes carrying recognized effectors that are expressed in the presence of ROS. #plantimmunity
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
Reposted by Freddy Boutrot
Our editors write:
- "Plant immunity: Engineering RLP receptors from the C side" rdcu.be/ePaS1
A brief highlight of this Article in @natbiotech.nature.com :
"Engineered pattern recognition receptors enhance broad-spectrum plant resistance" about swapping C-term domains rdcu.be/ePaTW
- "Plant immunity: Engineering RLP receptors from the C side" rdcu.be/ePaS1
A brief highlight of this Article in @natbiotech.nature.com :
"Engineered pattern recognition receptors enhance broad-spectrum plant resistance" about swapping C-term domains rdcu.be/ePaTW
November 10, 2025 at 1:30 PM
Our editors write:
- "Plant immunity: Engineering RLP receptors from the C side" rdcu.be/ePaS1
A brief highlight of this Article in @natbiotech.nature.com :
"Engineered pattern recognition receptors enhance broad-spectrum plant resistance" about swapping C-term domains rdcu.be/ePaTW
- "Plant immunity: Engineering RLP receptors from the C side" rdcu.be/ePaS1
A brief highlight of this Article in @natbiotech.nature.com :
"Engineered pattern recognition receptors enhance broad-spectrum plant resistance" about swapping C-term domains rdcu.be/ePaTW
Reposted by Freddy Boutrot
We wrote a review 📖 on hydathode immunity! Learn how bacteria exploit hydathodes to access the vasculature and open questions for future research.
📣 If you are curious about this topic, please consider applying for two open positions in my lab (until Nov23)! www.sciencedirect.com/science/arti...
📣 If you are curious about this topic, please consider applying for two open positions in my lab (until Nov23)! www.sciencedirect.com/science/arti...
Hydathodes at the forefront of plant immunity against vascular pathogens
Hydathodes are tiny plant organs that form an interface between the leaf surface and xylem vasculature. They facilitate excretion of xylem fluid under…
www.sciencedirect.com
November 4, 2025 at 10:43 AM
We wrote a review 📖 on hydathode immunity! Learn how bacteria exploit hydathodes to access the vasculature and open questions for future research.
📣 If you are curious about this topic, please consider applying for two open positions in my lab (until Nov23)! www.sciencedirect.com/science/arti...
📣 If you are curious about this topic, please consider applying for two open positions in my lab (until Nov23)! www.sciencedirect.com/science/arti...
Reposted by Freddy Boutrot
Plz RP. Come join us at @slcuplants.bsky.social @cam.ac.uk to study effector-targeted plant processes impacting plant cell biology and development.
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
November 6, 2025 at 6:51 PM
Plz RP. Come join us at @slcuplants.bsky.social @cam.ac.uk to study effector-targeted plant processes impacting plant cell biology and development.
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
Reposted by Freddy Boutrot
Cool new paper on receptor specificity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Two residues reprogram immunity receptors for nitrogen-fixing symbiosis - Nature
An investigation of plant receptor-like kinases identifies regions of these proteins that control whether immune or symbiotic signalling pathways are activated, with minimal changes to specific r...
www.nature.com
November 6, 2025 at 3:26 PM
Cool new paper on receptor specificity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Freddy Boutrot
Thrilled to share our latest review on receptor kinase processing in plants! 🌱
Huge congratulations to @adithya1972.bsky.social and Anna for leading this work, and a big thank you to our fantastic collaborator Martina-Ried Lasi for making this a truly rewarding team effort!
Huge congratulations to @adithya1972.bsky.social and Anna for leading this work, and a big thank you to our fantastic collaborator Martina-Ried Lasi for making this a truly rewarding team effort!
Shedding light on receptor kinase processing
journals.plos.org
November 4, 2025 at 8:25 AM
Thrilled to share our latest review on receptor kinase processing in plants! 🌱
Huge congratulations to @adithya1972.bsky.social and Anna for leading this work, and a big thank you to our fantastic collaborator Martina-Ried Lasi for making this a truly rewarding team effort!
Huge congratulations to @adithya1972.bsky.social and Anna for leading this work, and a big thank you to our fantastic collaborator Martina-Ried Lasi for making this a truly rewarding team effort!
Reposted by Freddy Boutrot
Postdoc position in my lab in Cologne starting early next year or latest in spring to get this exciting project started.
jobportal.uni-koeln.de/ausschreibun...
jobportal.uni-koeln.de/ausschreibun...
jobportal.uni-koeln.de
November 2, 2025 at 10:27 AM
Postdoc position in my lab in Cologne starting early next year or latest in spring to get this exciting project started.
jobportal.uni-koeln.de/ausschreibun...
jobportal.uni-koeln.de/ausschreibun...
Reposted by Freddy Boutrot
🚀 New preprint!
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
Natural variation in regulatory code revealed through Bayesian analysis of plant pan-genomes and pan-transcriptomes
Understanding the genetic code of cis-regulatory elements (CREs) is essential for engineering gene expression and modulating agronomic traits in crops. In plants, CREs underlying rapid evolution of ge...
biorxiv.org
October 29, 2025 at 4:47 PM
🚀 New preprint!
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
Reposted by Freddy Boutrot
The work is led by @weiweibio.bsky.social, a talented postdoc looking for faculty positions now and conceptualized both computational prediction and in lab validation. Computational implementation is a collaboration with Xing Wu, postdoc with @mexpositoalonso.bsky.social
Qs - contact us 💻🌱🧬
Qs - contact us 💻🌱🧬
October 29, 2025 at 4:55 PM
The work is led by @weiweibio.bsky.social, a talented postdoc looking for faculty positions now and conceptualized both computational prediction and in lab validation. Computational implementation is a collaboration with Xing Wu, postdoc with @mexpositoalonso.bsky.social
Qs - contact us 💻🌱🧬
Qs - contact us 💻🌱🧬
Reposted by Freddy Boutrot
N-hydroxy-pipecolic acid-mediated signal transduction and resistance requires DAWDLE url: academic.oup.com/plphys/artic...
N-hydroxy-pipecolic acid-mediated signal transduction and resistance requires DAWDLE
The Arabidopsis gene DAWDLE activates systemic acquired resistance by regulating immune-related genes induced by N-hydroxy-pipecolic acid.
academic.oup.com
October 27, 2025 at 4:13 PM
N-hydroxy-pipecolic acid-mediated signal transduction and resistance requires DAWDLE url: academic.oup.com/plphys/artic...
Reposted by Freddy Boutrot
Excited that our paper was just published! It's a revised version with new insights compared to the preprint. Thanks everyone from the @carahaney.bsky.social Lab!
www.cell.com/cell-reports...
www.cell.com/cell-reports...
A bacterial exotoxin-triggered plant immune response restricts pathogen growth
Thoms et al. demonstrate that perception of a bacterial exotoxin allows plants to
distinguish between closely related microbiota, which has consequences for rhizosphere
microbiome structure and functi...
www.cell.com
October 23, 2025 at 4:17 PM
Excited that our paper was just published! It's a revised version with new insights compared to the preprint. Thanks everyone from the @carahaney.bsky.social Lab!
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by Freddy Boutrot
Simon's mutant finally published! Well done, Satoko' lab with Harro, Tobimatsu, Tohge collaborations. Glucosylation of endogenous haustorium-inducing factors underpins kin avoidance in parasitic plants | Science www.science.org/doi/10.1126/...
Glucosylation of endogenous haustorium-inducing factors underpins kin avoidance in parasitic plants
Parasitic plants rarely attack themselves, suggesting the existence of a kin-avoidance mechanism. In the root parasitic plant Phtheirospermum japonicum, prehaustorium formation is triggered by host-se...
www.science.org
October 24, 2025 at 12:29 AM
Simon's mutant finally published! Well done, Satoko' lab with Harro, Tobimatsu, Tohge collaborations. Glucosylation of endogenous haustorium-inducing factors underpins kin avoidance in parasitic plants | Science www.science.org/doi/10.1126/...
Reposted by Freddy Boutrot
Humbly share our latest work led by @himanshuchhillar.bsky.social my phd student
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social
Uncoupling hypersensitive cell death response and disease resistance activated by effector-triggered immunity https://www.biorxiv.org/content/10.1101/2025.10.22.683861v1
October 23, 2025 at 11:51 PM
Humbly share our latest work led by @himanshuchhillar.bsky.social my phd student
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social
Reposted by Freddy Boutrot
Some of my favourite research from my PhD was submitted today... I feel very lucky to have worked on this project with such wonderful scientists (and lovely people!)
Please check it out on bioRxiv here👇🌱🦠
Please check it out on bioRxiv here👇🌱🦠
An elevated environmental temperature impairs accumulation of the pattern recognition receptor FLS2 https://www.biorxiv.org/content/10.1101/2025.10.20.683271v1
October 20, 2025 at 8:44 PM
Some of my favourite research from my PhD was submitted today... I feel very lucky to have worked on this project with such wonderful scientists (and lovely people!)
Please check it out on bioRxiv here👇🌱🦠
Please check it out on bioRxiv here👇🌱🦠
Reposted by Freddy Boutrot
📣 New @biorxiv-microbiol.bsky.social preprint, another joint-venture of @wolki95.bsky.social & @antonkraege.bsky.social, co-directed by @nicksnelders.bsky.social. Here’s a 🧵
Differential contributions of an antimicrobial effector from Verticillium dahliae to virulence and tomato microbiota assembly across natural soils https://www.biorxiv.org/content/10.1101/2025.09.30.679524v1
October 14, 2025 at 8:05 PM
📣 New @biorxiv-microbiol.bsky.social preprint, another joint-venture of @wolki95.bsky.social & @antonkraege.bsky.social, co-directed by @nicksnelders.bsky.social. Here’s a 🧵
Reposted by Freddy Boutrot
New pre-print from the team!
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
Primary metabolism underpins the execution of immune responses in different tissues of the same plant https://www.biorxiv.org/content/10.1101/2025.10.11.681807v1
October 14, 2025 at 7:16 AM
New pre-print from the team!
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
Uncovering Convergent Pattern Recognition Receptors Recognising Phytophthora Across Plant Lineages doi.org/10.1111/pbi....
Uncovering Convergent Pattern Recognition Receptors Recognising Phytophthora Across Plant Lineages
Pattern recognition receptors (PRRs) are pivotal for plant immunity, yet their discovery in crops is hindered by lineage-specific divergence. We demonstrate that microbe-associated molecular patterns....
doi.org
October 13, 2025 at 12:26 PM
Uncovering Convergent Pattern Recognition Receptors Recognising Phytophthora Across Plant Lineages doi.org/10.1111/pbi....
Reposted by Freddy Boutrot
Recognition of a phytocytokine by the DEPR1-SERK2 receptor complex confers multi-pathogen resistance in wheat #research #MolecularPlant cell.com/molecular-pl...
October 12, 2025 at 2:48 PM
Recognition of a phytocytokine by the DEPR1-SERK2 receptor complex confers multi-pathogen resistance in wheat #research #MolecularPlant cell.com/molecular-pl...
Reposted by Freddy Boutrot
Professorship in plant genetics.
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
www.berufungen.uni-kiel.de
October 12, 2025 at 9:01 AM
Professorship in plant genetics.
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
Reposted by Freddy Boutrot
Fran @frangordilloc.bsky.social and I wrote this piece on one of our favorite topics: the evolutionary relevance of co-receptors for immune receptor transfer in #plants 🌱
#EvoMPMI #MPMI
Check also the beautiful paper by Zhang et al. on the PRR STOMR and discover what happened to its co-receptor 😱
#EvoMPMI #MPMI
Check also the beautiful paper by Zhang et al. on the PRR STOMR and discover what happened to its co-receptor 😱
Lost & found: Reconstituting PRR immune function through co-receptor transfer
@isabelmonte.bsky.social highlights work revealing cross-species co-receptor transfer can overcome restricted taxonomic functionality in rice, pointing to strategies for crop protection
www.cell.com/cell-host-mi...
@isabelmonte.bsky.social highlights work revealing cross-species co-receptor transfer can overcome restricted taxonomic functionality in rice, pointing to strategies for crop protection
www.cell.com/cell-host-mi...
Lost and found: Reconstituting PRR immune function through co-receptor transfer
Plant immune receptors hold great promise for engineering broad-spectrum disease resistance,
but their effectiveness is very limited by restricted taxonomic functionality (RTF).
In this issue of Cell ...
www.cell.com
October 9, 2025 at 6:08 PM
Fran @frangordilloc.bsky.social and I wrote this piece on one of our favorite topics: the evolutionary relevance of co-receptors for immune receptor transfer in #plants 🌱
#EvoMPMI #MPMI
Check also the beautiful paper by Zhang et al. on the PRR STOMR and discover what happened to its co-receptor 😱
#EvoMPMI #MPMI
Check also the beautiful paper by Zhang et al. on the PRR STOMR and discover what happened to its co-receptor 😱
Reposted by Freddy Boutrot
Nataliia Rybchenko from @kwsgroup.bsky.social Ukraine presented her 'Sunflower' documentary at the #KWSScienceSlam.
Ukraine is the global leader in sunflower oil production, but amid the war, the sunflower has also become a symbol of freedom for Ukraine.
Documentary:
www.youtube.com/watch?v=2u2U...
Ukraine is the global leader in sunflower oil production, but amid the war, the sunflower has also become a symbol of freedom for Ukraine.
Documentary:
www.youtube.com/watch?v=2u2U...
October 9, 2025 at 4:46 AM
Nataliia Rybchenko from @kwsgroup.bsky.social Ukraine presented her 'Sunflower' documentary at the #KWSScienceSlam.
Ukraine is the global leader in sunflower oil production, but amid the war, the sunflower has also become a symbol of freedom for Ukraine.
Documentary:
www.youtube.com/watch?v=2u2U...
Ukraine is the global leader in sunflower oil production, but amid the war, the sunflower has also become a symbol of freedom for Ukraine.
Documentary:
www.youtube.com/watch?v=2u2U...
Reposted by Freddy Boutrot
🌽 Maize vs. Fusarium 🌽
Overexpressing a maize lipoxygenase (ZmLOX4) boosts resistance to Fusarium infection.
Glad that our maize Gene editing & transformation platform, at @rdplab.bsky.social, contributed to this research, led by the Lanubile's Lab.
▶️ doi.org/10.1093/jxb/...
Overexpressing a maize lipoxygenase (ZmLOX4) boosts resistance to Fusarium infection.
Glad that our maize Gene editing & transformation platform, at @rdplab.bsky.social, contributed to this research, led by the Lanubile's Lab.
▶️ doi.org/10.1093/jxb/...
October 6, 2025 at 9:51 AM
🌽 Maize vs. Fusarium 🌽
Overexpressing a maize lipoxygenase (ZmLOX4) boosts resistance to Fusarium infection.
Glad that our maize Gene editing & transformation platform, at @rdplab.bsky.social, contributed to this research, led by the Lanubile's Lab.
▶️ doi.org/10.1093/jxb/...
Overexpressing a maize lipoxygenase (ZmLOX4) boosts resistance to Fusarium infection.
Glad that our maize Gene editing & transformation platform, at @rdplab.bsky.social, contributed to this research, led by the Lanubile's Lab.
▶️ doi.org/10.1093/jxb/...
Reposted by Freddy Boutrot
A secreted citrus protease cleaves an outer membrane protein of the Huanglongbing pathogen https://www.biorxiv.org/content/10.1101/2025.10.06.680679v1
October 7, 2025 at 2:03 AM
A secreted citrus protease cleaves an outer membrane protein of the Huanglongbing pathogen https://www.biorxiv.org/content/10.1101/2025.10.06.680679v1
Reposted by Freddy Boutrot
💡 SPECIAL ISSUE VIEWPOINT 💡
Immune proteases are promising targets for protein engineering 🛠️ to boost disease resistance in plants 🌾 - Schuster et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪 @marischuster.bsky.social @aciattoni.bsky.social
Immune proteases are promising targets for protein engineering 🛠️ to boost disease resistance in plants 🌾 - Schuster et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪 @marischuster.bsky.social @aciattoni.bsky.social
October 6, 2025 at 10:32 AM
💡 SPECIAL ISSUE VIEWPOINT 💡
Immune proteases are promising targets for protein engineering 🛠️ to boost disease resistance in plants 🌾 - Schuster et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪 @marischuster.bsky.social @aciattoni.bsky.social
Immune proteases are promising targets for protein engineering 🛠️ to boost disease resistance in plants 🌾 - Schuster et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪 @marischuster.bsky.social @aciattoni.bsky.social