Danve Castroverde
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danvec.bsky.social
Danve Castroverde
@danvec.bsky.social
540 followers 1.1K following 450 posts
Associate Professor, Wilfrid Laurier University

Research interests: Plant immunity | Hormone signaling | Plant stress resilience

Funded by NSERC, CFI, ORF and NFRF
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danvec.bsky.social
Danve Castroverde @danvec.bsky.social · 11d
Congratulations to Diane and Emily for publishing "Pathways to Scientific Teaching vol. 2!" @macmillanusa.bsky.social

Thanks for the opportunity to contribute Lesson 2 on
plant hormone-mediated growth! 🌱🌱🌱

@laurierbiology.bsky.social @wilfridlaurieruni.bsky.social
Reposted by Danve Castroverde
dinglab.bsky.social
Ubiquitin recognition integrates plant immune signaling by cell-surface and intracellular receptors www.biorxiv.org/content/10.6...
www.biorxiv.org
February 10, 2026 at 6:00 AM
danvec.bsky.social
Structural basis of canonical TIR-NLR activation in plant innate immunity

www.biorxiv.org/content/10.6...
www.biorxiv.org
February 10, 2026 at 8:47 PM
Reposted by Danve Castroverde
nkinl.bsky.social
Out now in @natureportfolio.nature.com: PARM reveals gene regulation is far more predictable than thought. Lightweight, cell‑type specific, and experimentally validated. Enables functional prediction of regulatory mutations with just one dish of cells + one day of compute.
➡️ doi.org/10.1038/s415...
February 4, 2026 at 4:27 PM
Reposted by Danve Castroverde
natprot.nature.com
New Article! Designing and testing CRISPRi-based synthetic gene circuits in plants
Designing and testing CRISPRi-based synthetic gene circuits in plants
Nature Protocols, Published online: 04 February 2026; doi:10.1038/s41596-025-01312-yThis protocol details the design principles and procedures for building programmable CRISPRi-based gene circuits, and for testing individual components and the assembled circuits in various plant species using a high-throughput protoplast-based assay.
dlvr.it
February 4, 2026 at 3:43 PM
Reposted by Danve Castroverde
plantphys.bsky.social
Leaf it to science: Uncovering plant immune systems through technological advances (Xinnian Dong) doi.org/10.1093/plph... #PlantScience @aspbofficial
February 4, 2026 at 3:44 PM
danvec.bsky.social
Pseudomonas volatiles shape the root transcriptome and microbiome to promote plant growth under drought

www.biorxiv.org/content/10.6...
www.biorxiv.org
February 3, 2026 at 8:51 PM
danvec.bsky.social
The immunity-associated protein ACIP1 counteracts MIDD1 to coordinate xylem cell wall patterning

www.sciencedirect.com/science/arti...
The immunity-associated protein ACIP1 counteracts MIDD1 to coordinate xylem cell wall patterning
Cell wall patterning plays a crucial role in determining the function of plant cells.1 Protoxylem and metaxylem vessel cells form striped and pitted c…
www.sciencedirect.com
February 2, 2026 at 3:48 PM
danvec.bsky.social
Congratulations to Diane and Emily for publishing "Pathways to Scientific Teaching vol. 2!" @macmillanusa.bsky.social

Thanks for the opportunity to contribute Lesson 2 on
plant hormone-mediated growth! 🌱🌱🌱

@laurierbiology.bsky.social @wilfridlaurieruni.bsky.social
January 30, 2026 at 9:22 PM
danvec.bsky.social
Blue light can induce SAR in npr1 mutants! 🙀🌱🦠

www.biorxiv.org/content/10.6...
www.biorxiv.org
January 30, 2026 at 3:53 PM
danvec.bsky.social
Aging drives a program of DNA methylation decay in plant organs

www.science.org/doi/10.1126/...
Aging drives a program of DNA methylation decay in plant organs
Plants display a wide range of life spans and aging rates. Although dynamic changes to DNA methylation are a hallmark of aging in mammals, it is unclear whether similar molecular signatures reflect ra...
www.science.org
January 29, 2026 at 7:20 PM
danvec.bsky.social
Multiple protein structure alignment at scale with FoldMason

www.science.org/doi/10.1126/...
Multiple protein structure alignment at scale with FoldMason
Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...
www.science.org
January 29, 2026 at 7:19 PM
Reposted by Danve Castroverde
nature.com
Nature research paper: A benchmark of expert-level academic questions to assess AI capabilities

go.nature.com/45zkozH
A benchmark of expert-level academic questions to assess AI capabilities - Nature
Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.
go.nature.com
January 28, 2026 at 6:54 PM
danvec.bsky.social
Can we have one for plants please?! 😍🌱

Advancing regulatory variant effect prediction with AlphaGenome: www.nature.com/articles/s41...
Advancing regulatory variant effect prediction with AlphaGenome - Nature
AlphaGenome, a deep learning model that inputs 1-Mb DNA sequence to predict functional genomic tracks at single-base resolution across diverse modalities, outperforms existing models in variant effect...
www.nature.com
January 28, 2026 at 7:28 PM
Reposted by Danve Castroverde
googledeepmind.zpravobot.news.ap.brid.gy
Our breakthrough AI model AlphaGenome is helping scientists understand our DNA, predict the molecular impact of genetic changes, and drive new biological discoveries. 🧬

Find out more in https://xcancel.com/Nature ↓ 🔗↗️
https://goo.gle/4bXlV6y
Advancing regulatory variant effect prediction with AlphaGenome - Nature
AlphaGenome, a deep learning model that inputs 1-Mb DNA sequence to predict functional genomic tracks at single-base resolution across diverse modalities, outperforms existing models in variant effect prediction and enables comprehensive genomic analysis.
www.nature.com
January 28, 2026 at 4:05 PM
Reposted by Danve Castroverde
lultimoalbero.bsky.social
Our new paper is out in @nature.com

"Pesticide residues alter taxonomic and functional biodiversity in soils"

Largest in field assessmnt of pesticide effects on soil life🧬🇪🇺🦠🍄

www.nature.com/articles/s41...

@scienceinnovation.ec.europa.eu @panospanagos.bsky.social @mvanderheijden.bsky.social
January 28, 2026 at 4:17 PM
danvec.bsky.social
"This One Piece was not made with just one piece."

Love the annual #LEGO analogy & showcase when discussing cytoskeletal systems in #BI236 (Cell Biology class)!

@laurierbiology.bsky.social @wilfridlaurieruni.bsky.social
January 28, 2026 at 5:42 PM
danvec.bsky.social
An uORF-encoded mobile peptide sparks systemic stomatal immunity

www.cell.com/cell/fulltex...
An uORF-encoded mobile peptide sparks systemic stomatal immunity
In Arabidopsis, the uORF-encoded long-distance mobile peptide USIC in pathogen-infected local leaves activates systemic stomatal immunity, leading to stomatal closure in uninfected distal leaves.
www.cell.com
January 27, 2026 at 9:40 PM
danvec.bsky.social
PDLP5 regulates aquaporin-mediated hydrogen peroxide transport in Arabidopsis

www.biorxiv.org/content/10.6...
www.biorxiv.org
January 26, 2026 at 6:37 PM
danvec.bsky.social
The Effector RipAW Enhances Ralstonia solanacearum Invasion in Arabidopsis via CBP60g/SARD1‐Dependent and ‐Independent Pathways

bsppjournals.onlinelibrary.wiley.com/doi/10.1111/...
The Effector RipAW Enhances Ralstonia solanacearum Invasion in Arabidopsis via CBP60g/SARD1‐Dependent and ‐Independent Pathways
The effector RipAW facilitates R. solanacearum infection by suppressing CBP60g/SARD1-dependent SA pathway and triggering CBP60g/SARD1-independent root architecture changes.
bsppjournals.onlinelibrary.wiley.com
January 26, 2026 at 3:07 PM
Reposted by Danve Castroverde
newphyt.bsky.social
Decoding plant defense signaling using the defenseless mutant

Baral and Brosché

nph.onlinelibrary.wiley.com/doi/10.1111/...
Developmental and abiotic stress assays in Columbia-0 (Col-0) and mutants (abi1-1 and defenseless).
January 26, 2026 at 7:35 AM
danvec.bsky.social
Chromatin remodeling at the C-REPEAT BINDING FACTOR cluster controls growth retardation at low ambient temperature

academic.oup.com/plcell/advan...
Chromatin remodeling at the C-REPEAT BINDING FACTOR cluster controls growth retardation at low ambient temperature
Plants adapt to low ambient temperatures using a temperature-sensitive control system that remodels chromatin to control growth.
academic.oup.com
January 26, 2026 at 3:04 PM
Reposted by Danve Castroverde
fromani.bsky.social
This is a very special paper for me. I had the idea of combining transcription factor binding with chromatin in 2016/8. It took some time, but thanks to Fred and Vikas, we can finally share the story in @plos.org Genetics looking at chromatin states in Arabidopsis and Marchantia. #PlantScience
Chromatin state architecture governs transcription factor accessibility across plant genomes
Author summary In eukaryotes, DNA is tightly associated with histone proteins. Histone covalent modifications and histones isoforms, also called histone variants provide most of the complexity of chro...
journals.plos.org
January 23, 2026 at 3:17 PM
danvec.bsky.social
A negative feedback loop between TERMINAL FLOWER1 and LEAFY protects inflorescence indeterminacy

www.science.org/doi/10.1126/...
A negative feedback loop between TERMINAL FLOWER1 and LEAFY protects inflorescence indeterminacy
Inflorescences of flowering plants adopt diverse genetically programmed and environmentally tuned architectures. By contrast, continued maintenance of the stem-cell pool within the apical meristem is ...
www.science.org
January 22, 2026 at 7:57 PM
danvec.bsky.social
The salicylic acid receptor NPR1 mediates the polyubiquitination and degradation of the transcription factors ABF3/4 to inhibit drought resistance

onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
January 22, 2026 at 2:15 PM
danvec.bsky.social
🌱🌱🌱 Laurier Biology ( @laurierbiology.bsky.social ) is excited to host Dr. Tom DeFalco ( @westernu.ca ) on Friday (Jan 23rd).

He will be delivering his seminar on plant receptor kinases at 2:30 PM EST.

Please DM for the Zoom registration link! Hope to see you there.
January 21, 2026 at 8:05 PM