Emma McKay
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emmamckay.bsky.social
Emma McKay
@emmamckay.bsky.social
PhD candidate at Queen's University Belfast. Innate immunity, Inflammasomes and interaction proteomics.
Delighted to announce I passed my PhD viva yesterday! Many thanks to my examiners @kesslerbenedikt001.bsky.social and @gunnarns.bsky.social for the fantastic discussion and feedback. Thanks as well to my incredible supervisors Ben Collins and @colllab.bsky.social, and everyone in the labs!
October 1, 2025 at 2:22 PM
Reposted by Emma McKay
So proud of the new Dr @emmamckay.bsky.social for smashing her PhD viva! Huge thank you to her examiners @kesslerbenedikt001.bsky.social @gunnarns.bsky.social for great discussions on NLRP3 inflammasomes and proteomics - first student co-supervised with Prof Ben Collins 😊
October 1, 2025 at 2:07 PM
Great couple of days in Manchester for the excellent @britsocimm.bsky.social Innate Immunity and inflammation meeting #BSIInflammation25
September 13, 2025 at 5:19 PM
Brilliant couple of days attending the Irish Society for Immunology annual meeting in Galway. Great science in a beautiful place!
August 25, 2025 at 3:12 PM
Reposted by Emma McKay
Had a brilliant couple of days in Galway with the lab at the Irish Society for Immunology meeting - great science and great craic!!!
August 22, 2025 at 8:01 PM
Reposted by Emma McKay
NLRP3 inflammasomes can assemble on most organelles. A beautiful study by Hafner et al demonstrate the flexibility of organelles that can support inflammasome activation. Kudos to the authors on an intriguing study.
www.nature.com/articles/s41...
@ivahb.bsky.social @elvirab.bsky.social
Clustering of NLRP3 induced by membrane or protein scaffolds promotes inflammasome assembly - Nature Communications
NLRP3 inflammasome activation is critical for the induction of protective immunity, but molecular insights are still lacking. Here, the authors express NLRP3 variants targeted to different cellular lo...
www.nature.com
May 27, 2025 at 1:31 PM
Reposted by Emma McKay
If you’re looking to gain hands-on training in the basics of mass spectrometry and proteomics bioinformatics, then this course is for you! Make sure you’ve submitted your application by 6 April: www.ebi.ac.uk/training/eve...

Some financial assistance is available - see the course website.

🧪🧶🧬🖥️
March 27, 2025 at 10:43 AM
Reposted by Emma McKay
We are recruiting a student for a really exciting PhD project on understanding how high plasma suPAR predicts poor outcome in patients with ARDS @wwiem-qub.bsky.social #ARDS #criticialcare
- any questions please get in touch! (open to UK and RoI) www.findaphd.com/phds/project...
Understanding how high plasma soluble urokinase plasminogen activator receptor (suPAR) predicts poor outcome in patients with ARDS. at Queen’s University Belfast on FindAPhD.com
PhD Project - Understanding how high plasma soluble urokinase plasminogen activator receptor (suPAR) predicts poor outcome in patients with ARDS. at Queen’s University Belfast, listed on FindAPhD.com
www.findaphd.com
March 12, 2025 at 3:53 PM
Reposted by Emma McKay
The loss of TBK1, or both TBK1 and the related kinase IKKε, results in uncontrolled cell death–driven inflammation. We show that TBK1/IKKε prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells. www.science.org/doi/10.1126/...
TBK1 and IKKε prevent premature cell death by limiting the activity of both RIPK1 and NLRP3 death pathways
TBK1 and IKKe prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells.
www.science.org
March 7, 2025 at 8:49 PM
Reposted by Emma McKay
If pubmed is inaccessible at the moment, try @europepmc.org
March 1, 2025 at 5:31 PM
Reposted by Emma McKay
Thrilled to start 2025 with our latest findings! Yersinia invades macrophage cytosol to activate caspase-11 when caspase-8 or YopJ are inactive. www.cell.com/cell-reports...
Plasticity of cell death pathways ensures GSDMD activation during Yersinia pseudotuberculosis infection
Injection of YopJ by Yersinia pseudotuberculosis triggers RIPK1-dependent caspase-8 and GSDMD activation in murine macrophages; however, how macrophages defend against Yersinia when caspase-8 or YopJ ...
www.cell.com
January 16, 2025 at 11:09 PM
Reposted by Emma McKay
Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action https://www.biorxiv.org/content/10.1101/2024.12.21.629867v1
December 23, 2024 at 3:16 AM
Reposted by Emma McKay
Have you ever wondered whether pyroptotic corpses have functions beyond the grave? We made the surprising discovery that pyroptotic corpses are flagged by #filopodia to alert #DendriticCells they need autopsy. A short Bluetorial (1/13)👇with movies!
Link: rdcu.be/d2mjm
Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells
Nature Immunology - Pyroptotic cell death results in inflammation. Here the authors find that F-actin-rich structures formed during macrophage pyroptosis persist after cell death to activate...
rdcu.be
December 9, 2024 at 1:39 AM
Reposted by Emma McKay
Hi #TeamMassSpec! #FeMS+ has joined BlueSky! Please share and get the word out so we can build up a base here.
November 30, 2024 at 2:00 PM
Reposted by Emma McKay
@inflammasomelab.bsky.social was the lucky 100th added to this starter pack! Definitely one to follow for all the incredible #inflammasome #inflammation work they do!
go.bsky.app/QqJ9AgB
November 24, 2024 at 9:50 AM
Reposted by Emma McKay
The unofficial FeMS starter pack (until they join us on Bluesky :) anyway. If you're a woman working with a mass spectrometer please ask to be added! All women are welcome!

go.bsky.app/PUwu7fr
November 22, 2024 at 11:17 PM
Reposted by Emma McKay
First post on Bluesky, let’s share some websites offering many free illustrations for scientific figures 🖼️ 🧪 🌍 :

scidraw.io

bioart.niaid.nih.gov

www.phylopic.org

More well known but very nice though: www.freepik.com
SciDraw | Scientific Drawings
SciDraw - an open repository of science drawings
scidraw.io
November 23, 2024 at 6:57 AM
Reposted by Emma McKay
🎨 In case anyone need…

The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!

Check it out 👇
bioart.niaid.nih.gov
November 23, 2024 at 3:50 PM
Reposted by Emma McKay
My proteomics resources on Bluesky:

Proteomics Starter Pack (full): go.bsky.app/HH7kqEh PSP converted into a List so more researchers can be added: (bsky.app/profile/did:...)

Early Career Researchers in Proteomics Pack: go.bsky.app/Dp8PHX1

Single Cell Proteomics Pack: go.bsky.app/KYdPDb8
November 20, 2024 at 2:24 PM
Reposted by Emma McKay
The wave is rising 🌊🦋
In just a few days, we have surpassed the halfway mark of people in this #innateimmunity and #inflammation starter pack!
Contact me to be added or tag someone you think should be on here.
#immunosky #academicchatter

go.bsky.app/QqJ9AgB
November 19, 2024 at 7:30 PM
Reposted by Emma McKay
November 18, 2024 at 9:02 AM
Reposted by Emma McKay
Scaffolding of NLRP3 on osmotically swollen vesicles but not intermediate filaments promotes inflammasome assembly https://www.biorxiv.org/content/10.1101/2024.11.18.624139v1
Scaffolding of NLRP3 on osmotically swollen vesicles but not intermediate filaments promotes inflammasome assembly https://www.biorxiv.org/content/10.1101/2024.11.18.624139v1
Inflammasomes are nucleated by receptors that become activated upon cellular stresses including ioni
www.biorxiv.org
November 19, 2024 at 2:30 AM