Effie Apostolou lab
@efapostolou29.bsky.social
Interested in 3D chromatin, cell fate decisions and gene regulation
Reposted by Effie Apostolou lab
📢 We are hiring a bioinformatician!
📍 @gustaveroussy.fr - U981
⏳ 18 months contract
📩 hire.u981.hemonc@gmail.com
Thanks for reposting
#Recruitment #Genomics #Bioinformatics 👇
📍 @gustaveroussy.fr - U981
⏳ 18 months contract
📩 hire.u981.hemonc@gmail.com
Thanks for reposting
#Recruitment #Genomics #Bioinformatics 👇
January 23, 2026 at 10:04 AM
📢 We are hiring a bioinformatician!
📍 @gustaveroussy.fr - U981
⏳ 18 months contract
📩 hire.u981.hemonc@gmail.com
Thanks for reposting
#Recruitment #Genomics #Bioinformatics 👇
📍 @gustaveroussy.fr - U981
⏳ 18 months contract
📩 hire.u981.hemonc@gmail.com
Thanks for reposting
#Recruitment #Genomics #Bioinformatics 👇
Our study with @melnicklab on the discovery of a transient and tightly-regulated, plastic state of mature B cells during physiological immune response and potential links to aggressive lymphomas now out at NCB.👇Detailed threat by the amazing lead author @lscourzic.bsky.social!.
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December 30, 2025 at 7:16 PM
Our study with @melnicklab on the discovery of a transient and tightly-regulated, plastic state of mature B cells during physiological immune response and potential links to aggressive lymphomas now out at NCB.👇Detailed threat by the amazing lead author @lscourzic.bsky.social!.
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Massive effort from the 4D Nucleome consortium and excellent resource for the community! Don’t miss it!
A major output of the 4D Nucleome project appeared today. This is the joint effort of many scientists working together and (publicly) sharing data and results for several years. We hope this is of interest to many genome biologists!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An integrated view of the structure and function of the human 4D nucleome - Nature
The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitatin...
www.nature.com
December 18, 2025 at 9:15 AM
Massive effort from the 4D Nucleome consortium and excellent resource for the community! Don’t miss it!
Our study with @stadtfeldlab.bsky.social on the dual mechanism by which EHMT2 is repressing totipotency-associated vs lineage-specific loci is now out @emboreports.org. See thread by @cmuyehara.bsky.social who led the study with K Chatterjee. Full article here link.springer.com/article/10.1...
December 14, 2025 at 8:15 PM
Our study with @stadtfeldlab.bsky.social on the dual mechanism by which EHMT2 is repressing totipotency-associated vs lineage-specific loci is now out @emboreports.org. See thread by @cmuyehara.bsky.social who led the study with K Chatterjee. Full article here link.springer.com/article/10.1...
Don't miss the chance to attend the annual virtual meeting on the advances in Nuclear Topology and 3D chromatin Architecture in Cancer organized by @janeskok @iannisaifantis1 @artsinyc and Melnick. The registration is FREE (see barcode) and the speaker lineup SPECTACULAR.
November 5, 2025 at 3:06 PM
Don't miss the chance to attend the annual virtual meeting on the advances in Nuclear Topology and 3D chromatin Architecture in Cancer organized by @janeskok @iannisaifantis1 @artsinyc and Melnick. The registration is FREE (see barcode) and the speaker lineup SPECTACULAR.
Don't forget to register for the upcoming Keystone Symposium Epigenetics & Gene Regulation in Health and Disease (Geveva, March 03-06). Join us for fun discussions on chromatin mechanisms and therapeutic innovation! keysym.us/KSEpigenetic...
Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities | Keystone Symposia
Join us at the Keystone Symposia on Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities, March 2026, in Geneva, with field leaders!
keysym.us
October 14, 2025 at 3:12 AM
Don't forget to register for the upcoming Keystone Symposium Epigenetics & Gene Regulation in Health and Disease (Geveva, March 03-06). Join us for fun discussions on chromatin mechanisms and therapeutic innovation! keysym.us/KSEpigenetic...
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🚨For chromatin, epigenetics and non-coding RNA lovers: only two more weeks left to apply!
Check out our lab page and if interested don't hesitate to apply 3d-chrom.iit.it
Research Technician
app.ncoreplat.com/jobposition/...
Senior Researcher-Technologist
app.ncoreplat.com/jobposition/...
Check out our lab page and if interested don't hesitate to apply 3d-chrom.iit.it
Research Technician
app.ncoreplat.com/jobposition/...
Senior Researcher-Technologist
app.ncoreplat.com/jobposition/...
September 29, 2025 at 5:28 PM
👇👇👇
Honored and excited to be among the speakers in the upcoming #KSEpigenetics26 symposium! Thank you @kjarmache.bsky.social and @ckadoch.bsky.social for the invitation. Follow the link to register 👇👇👇
On behalf of @ckadoch.bsky.social and myself, we are pleased to present our upcoming @KeystoneSymposia, #KSEpigenetics26 Epigenetics and Gene Regulation in Health and Disease, March 2-5, in Geneva, Switzerland. keysym.us/KSEpigenetic...
Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities | Keystone Symposia
Join us at the Keystone Symposia on Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities, March 2026, in Geneva, with field leaders!
keysym.us
September 16, 2025 at 5:35 PM
Honored and excited to be among the speakers in the upcoming #KSEpigenetics26 symposium! Thank you @kjarmache.bsky.social and @ckadoch.bsky.social for the invitation. Follow the link to register 👇👇👇
Reposted by Effie Apostolou lab
Fraud, using A.I., impersonating medical professionals
Front page NY Times
www.nytimes.com/2025/09/05/t...
Front page NY Times
www.nytimes.com/2025/09/05/t...
September 7, 2025 at 2:04 PM
Fraud, using A.I., impersonating medical professionals
Front page NY Times
www.nytimes.com/2025/09/05/t...
Front page NY Times
www.nytimes.com/2025/09/05/t...
Reposted by Effie Apostolou lab
This is amazing: www.theatlantic.com/newsletters/...
Florida Decided There Were Too Many Children
The state’s elimination of vaccine mandates is a courageous first step toward decluttering itself of any excess kids.
www.theatlantic.com
September 5, 2025 at 4:33 PM
This is amazing: www.theatlantic.com/newsletters/...
Honored to be part of the "Reprogramming Stars" interview series by @cellreprolab.bsky.social @CellularReprogramming. Humbling title but very fun discussion about past and ongoing research, future directions, advice to new trainees and more. Check it out! www.liebertpub.com/doi/10.1177/...
Reprogramming Stars #23: Charting Cell Fate Crossroads from the Interplay Between Epigenetics, Transcription, and 3D Chromatin Architecture—An Interview with Dr. Effie Apostolou | Cellular Reprogrammi...
Cellular Reprogramming
www.liebertpub.com
August 26, 2025 at 9:24 AM
Honored to be part of the "Reprogramming Stars" interview series by @cellreprolab.bsky.social @CellularReprogramming. Humbling title but very fun discussion about past and ongoing research, future directions, advice to new trainees and more. Check it out! www.liebertpub.com/doi/10.1177/...
Another Exciting Fusion conference on 3D genome organization is coming up! #SGO25! Deadline for registration on September 1st! Hope to see many of you there!
@efapostolou29.bsky.social we are looking forward to your presentation at the #SGO25 ! Please share this with your followers to let them know the poster and registration deadline is fast approaching - Monday 01 September!
Register now ➡️https://bit.ly/4lhu1YX
Register now ➡️https://bit.ly/4lhu1YX
August 12, 2025 at 11:42 AM
Another Exciting Fusion conference on 3D genome organization is coming up! #SGO25! Deadline for registration on September 1st! Hope to see many of you there!
Reposted by Effie Apostolou lab
NEW
The White House is blocking the NIH from awarding new research grants for the rest of the fiscal year
Chokes off billions in research funding
Gift link www.wsj.com/politics/pol... with @nidhisubs.bsky.social
The White House is blocking the NIH from awarding new research grants for the rest of the fiscal year
Chokes off billions in research funding
Gift link www.wsj.com/politics/pol... with @nidhisubs.bsky.social
Trump Administration Puts New Chokehold on Billions in Health-Research Funding
The National Institutes of Health can’t award grants to outside researchers under a new White House restriction.
www.wsj.com
July 29, 2025 at 11:58 PM
NEW
The White House is blocking the NIH from awarding new research grants for the rest of the fiscal year
Chokes off billions in research funding
Gift link www.wsj.com/politics/pol... with @nidhisubs.bsky.social
The White House is blocking the NIH from awarding new research grants for the rest of the fiscal year
Chokes off billions in research funding
Gift link www.wsj.com/politics/pol... with @nidhisubs.bsky.social
Reposted by Effie Apostolou lab
The proposed budget slashes NIH by ~40%, devastating medical research, clinical trials, treatment breakthroughs—life-saving work.
Thousands of lives at risk for tax cuts for the rich? NO THANKS.
Tell your senators to oppose the cuts HERE:
zurl.co/qiKdX
zurl.co/RCR0y
#CutsCostLives
Thousands of lives at risk for tax cuts for the rich? NO THANKS.
Tell your senators to oppose the cuts HERE:
zurl.co/qiKdX
zurl.co/RCR0y
#CutsCostLives
Will the Senate Save NIH?
Rescuing biomedical research is every bit as important as saving Medicaid.
zurl.co
June 29, 2025 at 1:57 PM
The proposed budget slashes NIH by ~40%, devastating medical research, clinical trials, treatment breakthroughs—life-saving work.
Thousands of lives at risk for tax cuts for the rich? NO THANKS.
Tell your senators to oppose the cuts HERE:
zurl.co/qiKdX
zurl.co/RCR0y
#CutsCostLives
Thousands of lives at risk for tax cuts for the rich? NO THANKS.
Tell your senators to oppose the cuts HERE:
zurl.co/qiKdX
zurl.co/RCR0y
#CutsCostLives
Reposted by Effie Apostolou lab
Check out this new preprint with @distefanolab.bsky.social lab! The manuscript focuses on RNA processing in the form of sequestration into P-bodies in the context of development.
New preprint from the lab! With @brumbaugh-lab.bsky.social , we show that P-bodies sequester developmentally relevant RNAs to influence cell fate. miRNAs direct this conserved regulatory process, and manipulating it enhances totipotency and germ cell programming. www.biorxiv.org/content/10.1...
Selective RNA sequestration in biomolecular condensates directs cell fate transitions
Recent studies have emphasized the significance of biomolecular condensates in modulating gene expression through RNA processing and translational control. However, the functional roles of RNA condens...
www.biorxiv.org
May 13, 2025 at 3:12 AM
Check out this new preprint with @distefanolab.bsky.social lab! The manuscript focuses on RNA processing in the form of sequestration into P-bodies in the context of development.
Reposted by Effie Apostolou lab
I am looking for postdocs to join my group at NIH. Are you interested in Development, Evolution, Genetics, Genomics, and Human health? Please apply! www.training.nih.gov/jobs/pdf-mb-...
www.training.nih.gov
April 29, 2025 at 2:59 PM
I am looking for postdocs to join my group at NIH. Are you interested in Development, Evolution, Genetics, Genomics, and Human health? Please apply! www.training.nih.gov/jobs/pdf-mb-...
Reposted by Effie Apostolou lab
A few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.
🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
6 Postdoctoral and PhD positions in Center for Epigenetic Cell Memory (EpiC)
The Center for Epigenetic Cell Memory (EpiC) is a new Center of Excellence that will be established based on funding by the Danish National Research Foundation.
tinyurl.com
March 28, 2025 at 3:51 PM
A few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.
That’s huge!!! Congratulations Bing and welcome to NYC!!!
March 27, 2025 at 6:36 PM
That’s huge!!! Congratulations Bing and welcome to NYC!!!
The first cancer-related story from our group @WeillCornell
is now published in @MolecularCell. We investigate the role of hyperconnected 3D regulatory hubs in controlling oncogenic programs and properties in glioblastoma and also across 16 cancer types. www.cell.com/molecular-ce...
is now published in @MolecularCell. We investigate the role of hyperconnected 3D regulatory hubs in controlling oncogenic programs and properties in glioblastoma and also across 16 cancer types. www.cell.com/molecular-ce...
Three-dimensional regulatory hubs support oncogenic programs in glioblastoma
Here, Breves et al. profile the 3D enhancer-promoter connectomes of patient-derived
glioblastoma stem cells (GSCs), identify hyperconnected 3D regulatory “hubs” relevant
for GBM biology, examine the i...
www.cell.com
March 27, 2025 at 3:05 AM
The first cancer-related story from our group @WeillCornell
is now published in @MolecularCell. We investigate the role of hyperconnected 3D regulatory hubs in controlling oncogenic programs and properties in glioblastoma and also across 16 cancer types. www.cell.com/molecular-ce...
is now published in @MolecularCell. We investigate the role of hyperconnected 3D regulatory hubs in controlling oncogenic programs and properties in glioblastoma and also across 16 cancer types. www.cell.com/molecular-ce...
Reposted by Effie Apostolou lab
It’s crazy how receiving an automated -previously routine- email that my grant application is scheduled for review this summer brought smile to my face! It can still be trashed but at least it would be after peer-review!!! #PIlife #GirlsJustWanttoHaveFUNding #StandforNIH
March 21, 2025 at 10:07 PM
It’s crazy how receiving an automated -previously routine- email that my grant application is scheduled for review this summer brought smile to my face! It can still be trashed but at least it would be after peer-review!!! #PIlife #GirlsJustWanttoHaveFUNding #StandforNIH
USA has been traditionally on the receiving end of braindrain thanks to its world class research and a culture of inclusivity…! Let’s see how that will play out…
"Universities around the world have reported seeing an uptick in applications from U.S.-based researchers, who face an increasingly uncertain climate under President Donald Trump’s administration." ➡️ www.science.org/content/arti...
Overseas universities see opportunity in U.S. ‘brain drain’
But many U.S.-based scientists seeking to leave may struggle to find positions in countries grappling with funding issues of their own
www.science.org
March 19, 2025 at 11:42 AM
USA has been traditionally on the receiving end of braindrain thanks to its world class research and a culture of inclusivity…! Let’s see how that will play out…
Reposted by Effie Apostolou lab
A nonsensical threat to:
One of the most important advances in biotechnology of our time, already being used to successfully treat refractory cancers, enable genome editing, develop vaccines for infectious diseases for which there are none, treat autoimmune diseases, and more.
One of the most important advances in biotechnology of our time, already being used to successfully treat refractory cancers, enable genome editing, develop vaccines for infectious diseases for which there are none, treat autoimmune diseases, and more.
Exclusive: NIH officials have advised scientists to remove reference to mRNA vaccines from their grant applications, in expectation the Trump administration intends to abandon most research in the field.
By @arthurallen202.bsky.social
kffhealthnews.org/news/article...
By @arthurallen202.bsky.social
kffhealthnews.org/news/article...
Scientists Say NIH Officials Told Them To Scrub mRNA References on Grants - KFF Health News
Two senior scientists say National Institutes of Health officials advised them to remove references to mRNA vaccines in grant applications, and they fear the Trump administration will abandon a promis...
kffhealthnews.org
March 17, 2025 at 11:01 AM
A nonsensical threat to:
One of the most important advances in biotechnology of our time, already being used to successfully treat refractory cancers, enable genome editing, develop vaccines for infectious diseases for which there are none, treat autoimmune diseases, and more.
One of the most important advances in biotechnology of our time, already being used to successfully treat refractory cancers, enable genome editing, develop vaccines for infectious diseases for which there are none, treat autoimmune diseases, and more.
Reposted by Effie Apostolou lab
Our work on the regulation is out www.cell.com/stem-cell-re...! Congrats to our collaborators in the Vierbuchen and Mezey labs. It turns out that genetic variation has to be very much considered if you want to harness stem cells safely in biomedicine. #pluripotency #epigenetics #stemcells
Genetic variation modulates susceptibility to aberrant DNA hypomethylation and imprint deregulation in naive pluripotent stem cells
Pluripotent stem cells are susceptible to acquiring detrimental epigenetic abnormalities,
posing a hurdle to their safe use in biomedical applications. Using pluripotent cells
with defined genetic bac...
www.cell.com
March 13, 2025 at 8:41 PM
Our work on the regulation is out www.cell.com/stem-cell-re...! Congrats to our collaborators in the Vierbuchen and Mezey labs. It turns out that genetic variation has to be very much considered if you want to harness stem cells safely in biomedicine. #pluripotency #epigenetics #stemcells