Dafne Campigli Di Giammartino
@dafnecdg.bsky.social
Group Leader at Italian Institute of Technology.
RNA and Chromatin lover
RNA and Chromatin lover
🧬We’re hiring a Senior Bioinformatician @IIT in Genova 🇮🇹
Join our lab 👉 3d-chrom.iit.it to explore how non-coding RNAs shape 3D genome architecture
⏰ Deadline Nov 16th- only a few days left to apply!
app.ncoreplat.com/jobposition/...
Join our lab 👉 3d-chrom.iit.it to explore how non-coding RNAs shape 3D genome architecture
⏰ Deadline Nov 16th- only a few days left to apply!
app.ncoreplat.com/jobposition/...
https://app.ncoreplat.com/jobposition/679633/…
November 4, 2025 at 10:40 AM
🧬We’re hiring a Senior Bioinformatician @IIT in Genova 🇮🇹
Join our lab 👉 3d-chrom.iit.it to explore how non-coding RNAs shape 3D genome architecture
⏰ Deadline Nov 16th- only a few days left to apply!
app.ncoreplat.com/jobposition/...
Join our lab 👉 3d-chrom.iit.it to explore how non-coding RNAs shape 3D genome architecture
⏰ Deadline Nov 16th- only a few days left to apply!
app.ncoreplat.com/jobposition/...
🚨For chromatin, epigenetics and non-coding RNA lovers: only two more weeks left to apply!
Check out our lab page and if interested don't hesitate to apply 3d-chrom.iit.it
Research Technician
app.ncoreplat.com/jobposition/...
Senior Researcher-Technologist
app.ncoreplat.com/jobposition/...
Check out our lab page and if interested don't hesitate to apply 3d-chrom.iit.it
Research Technician
app.ncoreplat.com/jobposition/...
Senior Researcher-Technologist
app.ncoreplat.com/jobposition/...
September 29, 2025 at 2:10 PM
🚨For chromatin, epigenetics and non-coding RNA lovers: only two more weeks left to apply!
Check out our lab page and if interested don't hesitate to apply 3d-chrom.iit.it
Research Technician
app.ncoreplat.com/jobposition/...
Senior Researcher-Technologist
app.ncoreplat.com/jobposition/...
Check out our lab page and if interested don't hesitate to apply 3d-chrom.iit.it
Research Technician
app.ncoreplat.com/jobposition/...
Senior Researcher-Technologist
app.ncoreplat.com/jobposition/...
🎯 Our lab at the Italian Institute of Technology 3d-chrom.iit.it has a technician position available
If you are a scientist, interested in chromatin 🧬 epigenetics and non-coding RNAs and you are looking to work in a stimulating environment don’t hesitate to apply
👇
app.ncoreplat.com/jobposition/...
If you are a scientist, interested in chromatin 🧬 epigenetics and non-coding RNAs and you are looking to work in a stimulating environment don’t hesitate to apply
👇
app.ncoreplat.com/jobposition/...
August 4, 2025 at 2:41 PM
🎯 Our lab at the Italian Institute of Technology 3d-chrom.iit.it has a technician position available
If you are a scientist, interested in chromatin 🧬 epigenetics and non-coding RNAs and you are looking to work in a stimulating environment don’t hesitate to apply
👇
app.ncoreplat.com/jobposition/...
If you are a scientist, interested in chromatin 🧬 epigenetics and non-coding RNAs and you are looking to work in a stimulating environment don’t hesitate to apply
👇
app.ncoreplat.com/jobposition/...
🚨 Last Call for Applications! 🚨
If you're passionate about chromatin 🧬 and non-coding RNAs, you have only a few days left to apply:
Three fully-funded positions in my lab to study the cross-talk between epigenetics and 3D chromatin architecture.
Application links are available in the post below 👇
If you're passionate about chromatin 🧬 and non-coding RNAs, you have only a few days left to apply:
Three fully-funded positions in my lab to study the cross-talk between epigenetics and 3D chromatin architecture.
Application links are available in the post below 👇
To all chromatin and RNA enthusiasts 🧬 🧬 🧬
Our lab 3d-chrom.iit.it has several openings!
Looking for a well-paid position in a stimulating environment?
Apply here 👇
Senior Bioinformatician
iit.taleo.net/careersectio...
Senior Molecular Biology Researcher
iit.taleo.net/careersectio...
Our lab 3d-chrom.iit.it has several openings!
Looking for a well-paid position in a stimulating environment?
Apply here 👇
Senior Bioinformatician
iit.taleo.net/careersectio...
Senior Molecular Biology Researcher
iit.taleo.net/careersectio...
March 27, 2025 at 9:47 AM
🚨 Last Call for Applications! 🚨
If you're passionate about chromatin 🧬 and non-coding RNAs, you have only a few days left to apply:
Three fully-funded positions in my lab to study the cross-talk between epigenetics and 3D chromatin architecture.
Application links are available in the post below 👇
If you're passionate about chromatin 🧬 and non-coding RNAs, you have only a few days left to apply:
Three fully-funded positions in my lab to study the cross-talk between epigenetics and 3D chromatin architecture.
Application links are available in the post below 👇
I am so happy to see this work finally out 🎉 authors.elsevier.com/c/1kqIJ_Oylr...
Thanks to all the authors for the incredible teamwork!!!
Thanks to all the authors for the incredible teamwork!!!
March 27, 2025 at 9:43 AM
I am so happy to see this work finally out 🎉 authors.elsevier.com/c/1kqIJ_Oylr...
Thanks to all the authors for the incredible teamwork!!!
Thanks to all the authors for the incredible teamwork!!!
To all chromatin and RNA enthusiasts 🧬 🧬 🧬
Our lab 3d-chrom.iit.it has several openings!
Looking for a well-paid position in a stimulating environment?
Apply here 👇
Senior Bioinformatician
iit.taleo.net/careersectio...
Senior Molecular Biology Researcher
iit.taleo.net/careersectio...
Our lab 3d-chrom.iit.it has several openings!
Looking for a well-paid position in a stimulating environment?
Apply here 👇
Senior Bioinformatician
iit.taleo.net/careersectio...
Senior Molecular Biology Researcher
iit.taleo.net/careersectio...
February 27, 2025 at 4:05 PM
To all chromatin and RNA enthusiasts 🧬 🧬 🧬
Our lab 3d-chrom.iit.it has several openings!
Looking for a well-paid position in a stimulating environment?
Apply here 👇
Senior Bioinformatician
iit.taleo.net/careersectio...
Senior Molecular Biology Researcher
iit.taleo.net/careersectio...
Our lab 3d-chrom.iit.it has several openings!
Looking for a well-paid position in a stimulating environment?
Apply here 👇
Senior Bioinformatician
iit.taleo.net/careersectio...
Senior Molecular Biology Researcher
iit.taleo.net/careersectio...
Reposted by Dafne Campigli Di Giammartino
Here is the peer-reviewed version of our study showing how some TAD borders are essential for gene regulation and development.
Loss of a single CTCF motif is sufficient to cause embryonic lethality.
www.sciencedirect.com/science/arti...
Loss of a single CTCF motif is sufficient to cause embryonic lethality.
www.sciencedirect.com/science/arti...
Deletion of a single CTCF motif at the boundary of a chromatin domain with three FGF genes disrupts gene expression and embryonic development
Chromatin domains delimited by CTCF can restrict the range of enhancer action. However, disruption of some domain boundaries results in mild gene dysr…
www.sciencedirect.com
February 26, 2025 at 9:22 PM
Here is the peer-reviewed version of our study showing how some TAD borders are essential for gene regulation and development.
Loss of a single CTCF motif is sufficient to cause embryonic lethality.
www.sciencedirect.com/science/arti...
Loss of a single CTCF motif is sufficient to cause embryonic lethality.
www.sciencedirect.com/science/arti...
Reposted by Dafne Campigli Di Giammartino
New preprint from the lab investigating the role of cohesin in the establishment of chromatin loops and transcriptional programs after cell division or during cell fate transitions. Study led by @ukjinlee.bsky.social. Grateful to the whole team and NIH for support!
Post-mitotic transcriptional activation and 3D regulatory interactions show locus- and differentiation-specific sensitivity to cohesin depletion
Prior studies showed that structural loops collapse upon acute cohesin depletion, while regulatory enhancer-promoter (E-P) loops largely persist, consistent with minimal transcriptional changes. Howev...
bit.ly
February 24, 2025 at 11:27 PM
New preprint from the lab investigating the role of cohesin in the establishment of chromatin loops and transcriptional programs after cell division or during cell fate transitions. Study led by @ukjinlee.bsky.social. Grateful to the whole team and NIH for support!
Reposted by Dafne Campigli Di Giammartino
Together with @smandrup.bsky.social and Minna Kaikkonen we are happy to announce the 3rd Edition of the EMBO Workshop on #Enhancers and #Enhanceropathies. This time we will meet during the beautiful Danish summer (June 16-21).
Book the dates and register soon!!!
meetings.embo.org/event/25-enh...
Book the dates and register soon!!!
meetings.embo.org/event/25-enh...
Enhancer Mechanics and Enhanceropathies
Join us for the highly anticipated third EMBO workshop on Enhancer Mechanics and Enhanceropathies! Building on the success of our previous meetings in Santander (2021) and Marseilles (2023), this eve…
meetings.embo.org
January 31, 2025 at 2:35 PM
Together with @smandrup.bsky.social and Minna Kaikkonen we are happy to announce the 3rd Edition of the EMBO Workshop on #Enhancers and #Enhanceropathies. This time we will meet during the beautiful Danish summer (June 16-21).
Book the dates and register soon!!!
meetings.embo.org/event/25-enh...
Book the dates and register soon!!!
meetings.embo.org/event/25-enh...
Reposted by Dafne Campigli Di Giammartino
Very cool collaboration with @andersshansen.bsky.social's lab on how to calibrate Micro-C using our labs' previous live-cell estimates of looping probability!
Excited to share James Jusuf's preprint:
By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%)
We quantify mESC 36k loops: are generally rare (2.3%)
www.biorxiv.org/content/10.1...
By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%)
We quantify mESC 36k loops:
www.biorxiv.org/content/10.1...
January 17, 2025 at 1:17 PM
Very cool collaboration with @andersshansen.bsky.social's lab on how to calibrate Micro-C using our labs' previous live-cell estimates of looping probability!
Reposted by Dafne Campigli Di Giammartino
We are happy to share our enhancer scramble story, a strategy to create hundreds of stochastic deletions, inversions, and duplications within mammalian gene regulatory regions and associate these new architectures with gene expression levels 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
January 15, 2025 at 8:32 PM
We are happy to share our enhancer scramble story, a strategy to create hundreds of stochastic deletions, inversions, and duplications within mammalian gene regulatory regions and associate these new architectures with gene expression levels 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...