Prof Rick Adams
@drrickadams.bsky.social
Psychiatrist & Future Leaders Fellow at UCL, head of the Translational Computational Psychiatry lab: https://www.tcplab.org/. Working on psychosis, brain imaging, computational models of the brain. Co-Ed-in-Chief of @cpsyjournal.bluesky.social
Pinned
Prof Rick Adams
@drrickadams.bsky.social
· Sep 30
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
rb.gy
Post doc job alert 📢! Announcing a v exciting job on a Wellcome-funded project in my group at UCL, looking at auditory hallucinations... Advert here 👀: rb.gy/230w8l - deadline is end of Oct. Please apply! 1/5
Reposted by Prof Rick Adams
We're looking for a graduate research assistant for 2 years! Come work in my lab - cognitive neuroscience / computational neurology (🧠https://ndcn.ox.ac.uk/research/computational-neurology), in Oxford, on motivation in Parkinson's disease. Patient-facing role. Apply now:
November 6, 2025 at 10:13 PM
We're looking for a graduate research assistant for 2 years! Come work in my lab - cognitive neuroscience / computational neurology (🧠https://ndcn.ox.ac.uk/research/computational-neurology), in Oxford, on motivation in Parkinson's disease. Patient-facing role. Apply now:
Reposted by Prof Rick Adams
A new inpatient trial of repeated ketamine infusions found no significant advantage over an active psychoactive control in reducing depressive symptoms. Read more: https://bit.ly/4qvn7To  #Psychiatry #Depression
Serial Ketamine Infusions Fail to Outperform Placebo in New Trial
A new clinical trial found that repeated ketamine infusions offered no meaningful advantage over an active placebo for depression patients.
bit.ly
October 29, 2025 at 8:46 PM
A new inpatient trial of repeated ketamine infusions found no significant advantage over an active psychoactive control in reducing depressive symptoms. Read more: https://bit.ly/4qvn7To  #Psychiatry #Depression
Reposted by Prof Rick Adams
🚀 We’re hiring - Join our lab 🚀
🔍 Hiring: PhD (75% TV-L) & Postdoc (100% TV-L)
🧠 fMRI, VR, EEG, modelling
We combine a range of cognitive neuroscience methods to study flexible behaviour.
📅 Start: Feb 2026 or later | ⏳ Apply by Nov 3!
More details:
tinyurl.com/ms3a9ajt
#CognitiveNeuroscience
🔍 Hiring: PhD (75% TV-L) & Postdoc (100% TV-L)
🧠 fMRI, VR, EEG, modelling
We combine a range of cognitive neuroscience methods to study flexible behaviour.
📅 Start: Feb 2026 or later | ⏳ Apply by Nov 3!
More details:
tinyurl.com/ms3a9ajt
#CognitiveNeuroscience
October 27, 2025 at 11:57 AM
🚀 We’re hiring - Join our lab 🚀
🔍 Hiring: PhD (75% TV-L) & Postdoc (100% TV-L)
🧠 fMRI, VR, EEG, modelling
We combine a range of cognitive neuroscience methods to study flexible behaviour.
📅 Start: Feb 2026 or later | ⏳ Apply by Nov 3!
More details:
tinyurl.com/ms3a9ajt
#CognitiveNeuroscience
🔍 Hiring: PhD (75% TV-L) & Postdoc (100% TV-L)
🧠 fMRI, VR, EEG, modelling
We combine a range of cognitive neuroscience methods to study flexible behaviour.
📅 Start: Feb 2026 or later | ⏳ Apply by Nov 3!
More details:
tinyurl.com/ms3a9ajt
#CognitiveNeuroscience
Reposted by Prof Rick Adams
Looking for a PhD? Interested in cognitive computational neuroscience, motivation and decision-making? See our project listed in the BBSRC MIBTP competition for funding for a 4-year PhD in the @msnlab.bsky.social in the @thechbh.bsky.social. Deadline 27/11. More info: tinyurl.com/5d5vz8m7
The computational and neural dynamics of human motivation and cognitive control at University of Birmingham on FindAPhD.com
PhD Project - The computational and neural dynamics of human motivation and cognitive control at University of Birmingham, listed on FindAPhD.com
www.findaphd.com
October 23, 2025 at 9:36 AM
Looking for a PhD? Interested in cognitive computational neuroscience, motivation and decision-making? See our project listed in the BBSRC MIBTP competition for funding for a 4-year PhD in the @msnlab.bsky.social in the @thechbh.bsky.social. Deadline 27/11. More info: tinyurl.com/5d5vz8m7
Reposted by Prof Rick Adams
New blogpost on my concerns about Wellcome LEAP new $50m program on autism/microbiome links. deevybee.blogspot.com/2025/10/a-le...
#autism #microbiome #biomarkers #diagnostic
#autism #microbiome #biomarkers #diagnostic
A LEAP into the future, or off a cliff: Wellcome LEAP's new $50M program
A few days ago, I saw this post on LinkedIn: How does the gut microbiome shape early brain development? That’s what FORM, a new $50 million...
deevybee.blogspot.com
October 20, 2025 at 1:53 PM
New blogpost on my concerns about Wellcome LEAP new $50m program on autism/microbiome links. deevybee.blogspot.com/2025/10/a-le...
#autism #microbiome #biomarkers #diagnostic
#autism #microbiome #biomarkers #diagnostic
Reposted by Prof Rick Adams
Very thought-provoking post by @prakhargodara.bsky.social. Is confirmation bias/positivity bias a statistical "ghost" of model specification? Specifically not including temporally decaying learning rates? The evidence suggests this is not the case and here is why (1/n)
Is confirmation bias a real cognitive flaw, or a statistical ghost created by our models? My new PNAS paper shows a startling result: fitting Q-learning models to behavior in bandit tasks detect a bias, even from the behavior of a perfectly rational Bayesian learner.
October 19, 2025 at 8:22 AM
Very thought-provoking post by @prakhargodara.bsky.social. Is confirmation bias/positivity bias a statistical "ghost" of model specification? Specifically not including temporally decaying learning rates? The evidence suggests this is not the case and here is why (1/n)
Reposted by Prof Rick Adams
Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain.
A brief rundown...
www.nature.com/articles/s41...
A brief rundown...
www.nature.com/articles/s41...
A parabrachial hub for need-state control of enduring pain - Nature
Activity in a set of parabranchial neurons in the mouse brain is increased during chronic pain, predicts coping behaviour, and can be modulated by circuits activated by survival threats.
www.nature.com
October 9, 2025 at 1:15 PM
Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain.
A brief rundown...
www.nature.com/articles/s41...
A brief rundown...
www.nature.com/articles/s41...
Reposted by Prof Rick Adams
New preprint! What happens if you add neuromodulation to spiking neural networks and let them go wild with it? TLDR: it can improve performance especially in challenging sensory processing tasks. Explainer thread below. 🤖🧠🧪 www.biorxiv.org/content/10.1...
Neuromodulation enhances dynamic sensory processing in spiking neural network models
Neuromodulators allow circuits to dynamically change their biophysical properties in a context-sensitive way. In addition to their role in learning, neuromodulators have been suggested to play a role ...
www.biorxiv.org
September 18, 2025 at 4:30 PM
New preprint! What happens if you add neuromodulation to spiking neural networks and let them go wild with it? TLDR: it can improve performance especially in challenging sensory processing tasks. Explainer thread below. 🤖🧠🧪 www.biorxiv.org/content/10.1...
Reposted by Prof Rick Adams
New #job alert! Clinical research fellow / postdoc in #computationalpsychiatry at the @mpc-comppsych.bsky.social / @uclqsion.bsky.social and UCL psychiatry. We will aim to understand the computations engaged by serotonin in the treatment of depression. Please re-sky. www.ucl.ac.uk/work-at-ucl/...
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
October 1, 2025 at 3:58 PM
New #job alert! Clinical research fellow / postdoc in #computationalpsychiatry at the @mpc-comppsych.bsky.social / @uclqsion.bsky.social and UCL psychiatry. We will aim to understand the computations engaged by serotonin in the treatment of depression. Please re-sky. www.ucl.ac.uk/work-at-ucl/...
Post doc job alert 📢! Announcing a v exciting job on a Wellcome-funded project in my group at UCL, looking at auditory hallucinations... Advert here 👀: rb.gy/230w8l - deadline is end of Oct. Please apply! 1/5
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
rb.gy
September 30, 2025 at 1:01 PM
Post doc job alert 📢! Announcing a v exciting job on a Wellcome-funded project in my group at UCL, looking at auditory hallucinations... Advert here 👀: rb.gy/230w8l - deadline is end of Oct. Please apply! 1/5
Reposted by Prof Rick Adams
Life satisfaction mostly declines with age. Previous findings (esp. the famous U-shaped age-SWB trajectory) were artifacts of misspecified models. doi.org/10.1093/esr/...
September 29, 2025 at 12:14 PM
Life satisfaction mostly declines with age. Previous findings (esp. the famous U-shaped age-SWB trajectory) were artifacts of misspecified models. doi.org/10.1093/esr/...
Reposted by Prof Rick Adams
This study of intelligence in the UK Biobank is typical of a lot of current social science genomics. Impressive technically, and not over-interpreted. But still, a main result gets lost in the sauce. Within-families, the direct-effect polygenic score explains no more that 1-3% of the variance. /1
Imputation of fluid intelligence scores reduces ascertainment bias and increases power for analyses of common and rare variants
Studying the genetics of measures of intelligence can help us understand the neurobiology of cognitive function and the aetiology of rare neurodevelopmental conditions. The largest previous genetic st...
www.researchsquare.com
September 22, 2025 at 12:27 PM
This study of intelligence in the UK Biobank is typical of a lot of current social science genomics. Impressive technically, and not over-interpreted. But still, a main result gets lost in the sauce. Within-families, the direct-effect polygenic score explains no more that 1-3% of the variance. /1
Reposted by Prof Rick Adams
Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
September 5, 2025 at 2:59 AM
Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
Reposted by Prof Rick Adams
New paper in CPsy - 'Computational Mechanisms of Approach-Avoidance Conflict Predictively Differentiate Between Affective and Substance Use Disorders' from Marishka Mehta and the group of @rssmith.bsky.social
doi.org/10.5334/cpsy...
doi.org/10.5334/cpsy...
Computational Mechanisms of Approach-Avoidance Conflict Predictively Differentiate Between Affective and Substance Use Disorders | Computational Psychiatry
doi.org
September 15, 2025 at 4:34 PM
New paper in CPsy - 'Computational Mechanisms of Approach-Avoidance Conflict Predictively Differentiate Between Affective and Substance Use Disorders' from Marishka Mehta and the group of @rssmith.bsky.social
doi.org/10.5334/cpsy...
doi.org/10.5334/cpsy...
Reposted by Prof Rick Adams
New paper in CPsy 📢 - from Mostafa Abdou, @raziasahi.bsky.social, Thomas Hull, @eriknook.bsky.social and @nathanieldaw.bsky.social - cpsyjournal.org/articles/10....
September 15, 2025 at 4:31 PM
New paper in CPsy 📢 - from Mostafa Abdou, @raziasahi.bsky.social, Thomas Hull, @eriknook.bsky.social and @nathanieldaw.bsky.social - cpsyjournal.org/articles/10....
Reposted by Prof Rick Adams
Delighted to share our work on replay and successor representations! We find replay during very short task pauses in human visual cortex that is linked to learning SRs & happens when learning is implicit. Study led by @lnnrtwttkhn.bsky.social
#compneuro #neuroskyence
www.pnas.org/doi/10.1073/...
#compneuro #neuroskyence
www.pnas.org/doi/10.1073/...
Replay in the human visual cortex during brief task pauses is linked to implicit learning of successor representations | PNAS
Humans can implicitly learn about multistep sequential relationships between events
in the environment from their statistical co-occurrence. Theore...
www.pnas.org
August 22, 2025 at 4:43 PM
Delighted to share our work on replay and successor representations! We find replay during very short task pauses in human visual cortex that is linked to learning SRs & happens when learning is implicit. Study led by @lnnrtwttkhn.bsky.social
#compneuro #neuroskyence
www.pnas.org/doi/10.1073/...
#compneuro #neuroskyence
www.pnas.org/doi/10.1073/...
Reposted by Prof Rick Adams
Very happy to share my first preprint from @oxexppsy.bsky.social @oxneuro.bsky.social ! We (me + co-first authors @lilweb.bsky.social @mirunarascu.bsky.social + PI @mkflugge.bsky.social + many others) used transcranial focused ultrasound stimulation (TUS/tFUS/LIFU) of the human amygdala ... (1/15)
August 20, 2025 at 5:58 AM
Very happy to share my first preprint from @oxexppsy.bsky.social @oxneuro.bsky.social ! We (me + co-first authors @lilweb.bsky.social @mirunarascu.bsky.social + PI @mkflugge.bsky.social + many others) used transcranial focused ultrasound stimulation (TUS/tFUS/LIFU) of the human amygdala ... (1/15)
Reposted by Prof Rick Adams
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
August 10, 2025 at 6:23 PM
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Reposted by Prof Rick Adams
I’m elated to share our latest publication - out now in @natmentalhealth.nature.com! www.nature.com/articles/s44... - tour de force by @leahbanellis.bsky.social @brainandstomach.bsky.social and the rest of the VMP team!
Stomach–brain coupling indexes a dimensional signature of mental health - Nature Mental Health
Using a relatively large and diverse sample of mostly young adults, this study by Banellis, Rebollo and colleagues examines associations between regional stomach–brain coupling and mental health and i...
www.nature.com
July 30, 2025 at 10:25 AM
I’m elated to share our latest publication - out now in @natmentalhealth.nature.com! www.nature.com/articles/s44... - tour de force by @leahbanellis.bsky.social @brainandstomach.bsky.social and the rest of the VMP team!
Reposted by Prof Rick Adams
July 23, 2025 at 9:51 AM
Reposted by Prof Rick Adams
Attractors are usually not mechanisms - new blog post: open.substack.com/pub/kording/...
Attractors are usually not mechanisms
The mathematical objects can not be. And the "attractor models" have not been established as mechanisms in mammals
open.substack.com
July 8, 2025 at 2:40 PM
Attractors are usually not mechanisms - new blog post: open.substack.com/pub/kording/...
Reposted by Prof Rick Adams
Clinical research in England is wild! 3+ years, 20+ meetings, 200+ documents, 500+ emails is what it can take to open a fully funded, observational non-CTIMP study.
Thank you @chrischirp.bsky.social and colleagues for calling attention to this urgent, solvable crisis!
www.bmj.com/content/390/...
Thank you @chrischirp.bsky.social and colleagues for calling attention to this urgent, solvable crisis!
www.bmj.com/content/390/...
Health research in England is grinding to a halt
Wes Streeting, the UK health and social care secretary, announced in 2024 that “the NHS is broken” against a background of ballooning waiting lists, delays in disease detection, and reduced staff prod...
www.bmj.com
July 6, 2025 at 10:00 AM
Clinical research in England is wild! 3+ years, 20+ meetings, 200+ documents, 500+ emails is what it can take to open a fully funded, observational non-CTIMP study.
Thank you @chrischirp.bsky.social and colleagues for calling attention to this urgent, solvable crisis!
www.bmj.com/content/390/...
Thank you @chrischirp.bsky.social and colleagues for calling attention to this urgent, solvable crisis!
www.bmj.com/content/390/...
Reposted by Prof Rick Adams
Thrilled to see our TinyRNN paper in @nature! We show how tiny RNNs predict choices of individual subjects accurately while staying fully interpretable. This approach can transform how we model cognitive processes in both healthy and disordered decisions. doi.org/10.1038/s415...
Discovering cognitive strategies with tiny recurrent neural networks - Nature
Modelling biological decision-making with tiny recurrent neural networks enables more accurate predictions of animal choices than classical cognitive models and offers insights into the underlying cog...
doi.org
July 2, 2025 at 7:03 PM
Thrilled to see our TinyRNN paper in @nature! We show how tiny RNNs predict choices of individual subjects accurately while staying fully interpretable. This approach can transform how we model cognitive processes in both healthy and disordered decisions. doi.org/10.1038/s415...
Reposted by Prof Rick Adams
Our new study published in TheLancetPsych! We found that pramipexole augmentation substantially reduced depressive symptoms in patients with treatment-resistant depression over 48 weeks of treatment. This is an important advance in how we treat depression! 1/6
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Pramipexole augmentation for the acute phase of treatment-resistant, unipolar depression: a placebo-controlled, double-blind, randomised trial in the UK
In this trial involving participants with treatment-resistant depression, pramipexole
augmentation of antidepressant treatment, at a target dose of 2·5 mg, demonstrated
a reduction in symptoms relativ...
www.thelancet.com
June 30, 2025 at 3:54 AM
Our new study published in TheLancetPsych! We found that pramipexole augmentation substantially reduced depressive symptoms in patients with treatment-resistant depression over 48 weeks of treatment. This is an important advance in how we treat depression! 1/6
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Reposted by Prof Rick Adams
Looking forward to #RLDM2025!
🌀 I'll be talking about why we get caught in repetitive negative thinking patterns like rumination and worry at the Thursday poster session (poster #21) — come say hi if you're around!
🌀 I'll be talking about why we get caught in repetitive negative thinking patterns like rumination and worry at the Thursday poster session (poster #21) — come say hi if you're around!
June 11, 2025 at 1:17 PM
Looking forward to #RLDM2025!
🌀 I'll be talking about why we get caught in repetitive negative thinking patterns like rumination and worry at the Thursday poster session (poster #21) — come say hi if you're around!
🌀 I'll be talking about why we get caught in repetitive negative thinking patterns like rumination and worry at the Thursday poster session (poster #21) — come say hi if you're around!