Chris Pook
@drchrispook.bsky.social
Biochemistry, mass spectrometry, metabolomics, chromatography, health, nutrition, physiology, chemoinformatics, computational mass spec. Personal account. #SexMatters #SexNotGender https://thepoliticalerasureofsex.org/
https://projectnettie.wordpress.com/
https://projectnettie.wordpress.com/
Pinned
Chris Pook
@drchrispook.bsky.social
· Dec 18
Polar metabolomics using trichloroacetic acid extraction and porous graphitic carbon stationary phase - Metabolomics
Introduction Accurately identifying and quantifying polar metabolites using untargeted metabolomics has proven challenging in comparison to mid to non-polar metabolites. Hydrophilic interaction chroma...
link.springer.com
It's here! "Polar metabolomics using trichloroacetic acid extraction and porous graphitic carbon stationary phase". The 2nd paper from Frankie Day's PhD & 1 of only 3 in the literature applying porous graphitic carbon stationary phase for #Metabolomics.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Let's not forget that this guy convinced women he could make their breasts larger using hypnosis. I'm not even joking. That is the calibre of leadership in the current Green Party of England and Wales. A party I used to be a proud member of.
www.lbc.co.uk/article/zack...
www.lbc.co.uk/article/zack...
December 27, 2025 at 9:10 AM
Let's not forget that this guy convinced women he could make their breasts larger using hypnosis. I'm not even joking. That is the calibre of leadership in the current Green Party of England and Wales. A party I used to be a proud member of.
www.lbc.co.uk/article/zack...
www.lbc.co.uk/article/zack...
Merry Christmas, tweeps. 🌺🌺🌺🌺
December 25, 2025 at 6:49 AM
Merry Christmas, tweeps. 🌺🌺🌺🌺
Reposted by Chris Pook
Breakthrough of the year? Renewable energy www.science.org/content/arti...
December 21, 2025 at 7:54 PM
Breakthrough of the year? Renewable energy www.science.org/content/arti...
Another banana flower coming. Happy solstice, everyone!
December 21, 2025 at 8:46 PM
Another banana flower coming. Happy solstice, everyone!
Lemon Chiffon! 🌺🤩
December 18, 2025 at 9:04 PM
Lemon Chiffon! 🌺🤩
Reposted by Chris Pook
Back in Blighty 2025, and there's nowhere else I'd rather be than in an English woodland in early May. Green, fresh and full of wonders and promise. Herb-Paris (Paris quadrifolia) is scarce here in Hampshire, but if you know where to look...
@bsbibotany.bsky.social
@bsbibotany.bsky.social
December 17, 2025 at 7:55 PM
Back in Blighty 2025, and there's nowhere else I'd rather be than in an English woodland in early May. Green, fresh and full of wonders and promise. Herb-Paris (Paris quadrifolia) is scarce here in Hampshire, but if you know where to look...
@bsbibotany.bsky.social
@bsbibotany.bsky.social
Reposted by Chris Pook
December 17, 2025 at 10:29 PM
It's been a while since I've accidentally added ammonium as well as formic to acetonitrile. Ammonium formate is largely insoluble in this solvent so you get this white cloud which then flocculates as on the right. Pretty, but a bit of a waste. 🙄
December 17, 2025 at 8:20 PM
It's been a while since I've accidentally added ammonium as well as formic to acetonitrile. Ammonium formate is largely insoluble in this solvent so you get this white cloud which then flocculates as on the right. Pretty, but a bit of a waste. 🙄
I'm pretty sure this happens to plasma metabolites too. That's why consistent and rapid sample processing is so important.
December 17, 2025 at 7:09 PM
I'm pretty sure this happens to plasma metabolites too. That's why consistent and rapid sample processing is so important.
I don't know what this one is called. It's in my friend's tropical garden. Very pretty though. 🌺
December 17, 2025 at 7:07 PM
I don't know what this one is called. It's in my friend's tropical garden. Very pretty though. 🌺
Reposted by Chris Pook
Another low point of cultural relativism: telling African women that cutting off their clitoris with a rusty knife, isn't that bad really, because "culture". #FGM
The new colonialism....
jme.bmj.com/content/earl...
The new colonialism....
jme.bmj.com/content/earl...
Harms of the current global anti-FGM campaign
Traditional female genital practices, though long-standing in many cultures, have become the focus of an expansive global campaign against ‘female genital mutilation’ (FGM). In this article, we critic...
jme.bmj.com
December 17, 2025 at 7:24 AM
Another low point of cultural relativism: telling African women that cutting off their clitoris with a rusty knife, isn't that bad really, because "culture". #FGM
The new colonialism....
jme.bmj.com/content/earl...
The new colonialism....
jme.bmj.com/content/earl...
Reposted by Chris Pook
One of the biggest challenges of IMS is the multiple gas phase conformers, generating multiple IMS peaks for a single, pure analyte.
The Nagy lab have worked out how to greatly reduce these, through ion heating
#glycotime
The Nagy lab have worked out how to greatly reduce these, through ion heating
#glycotime
Improving Peak Capacity in Glycan Ion Mobility Separations through Traveling Wave-Based Ion Heating pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
December 15, 2025 at 7:55 PM
One of the biggest challenges of IMS is the multiple gas phase conformers, generating multiple IMS peaks for a single, pure analyte.
The Nagy lab have worked out how to greatly reduce these, through ion heating
#glycotime
The Nagy lab have worked out how to greatly reduce these, through ion heating
#glycotime
Rapid quantitation of NAD+/NADH and NADPH/NADP+ with mass spectrometry by using calibration constants #RedoxBiol www.sciencedirect.com/science/arti...
Rapid quantitation of NAD+/NADH and NADPH/NADP+ with mass spectrometry by using calibration constants
NAD+/NADH and NADPH/NADP+ are important indicators of cellular redox status, but they cannot be reliably calculated from the relative intensities of m…
www.sciencedirect.com
December 15, 2025 at 1:05 AM
Reposted by Chris Pook
Keira Bell: "There are children who have already been down this pathway – I'm one of them. Why aren't we doing follow-ups with people like me?"
A good question.
www.bbc.com/news/article...
A good question.
www.bbc.com/news/article...
December 14, 2025 at 11:25 PM
Keira Bell: "There are children who have already been down this pathway – I'm one of them. Why aren't we doing follow-ups with people like me?"
A good question.
www.bbc.com/news/article...
A good question.
www.bbc.com/news/article...
Well, that's impressive. Good work, Rachel Erin. 🌺🌺🌺
December 13, 2025 at 8:05 AM
Well, that's impressive. Good work, Rachel Erin. 🌺🌺🌺
First gladiolus flowering. 🪻💜
December 13, 2025 at 12:44 AM
First gladiolus flowering. 🪻💜
First gladiolus flower. 💜
December 12, 2025 at 11:06 PM
First gladiolus flower. 💜
It always amazes me when I try to reproduce a published analytical chemistry method and it completely fails. Not even a hint of the result reported in the paper. Just nothing.
#AnaChem
#AnaChem
December 11, 2025 at 10:29 PM
It always amazes me when I try to reproduce a published analytical chemistry method and it completely fails. Not even a hint of the result reported in the paper. Just nothing.
#AnaChem
#AnaChem
Reposted by Chris Pook
Mini Rachel Erin. 🌺💜
December 11, 2025 at 5:13 AM
Mini Rachel Erin. 🌺💜
Wow.
December 10, 2025 at 7:23 PM
Wow.
Miniature 5th dimension. 🌺💜
December 10, 2025 at 10:20 AM
Miniature 5th dimension. 🌺💜
Reposted by Chris Pook
Sorry, lads, it's not a convincing argument to say trans women are women but women defending their hard-won legal rights are animals.
This persistent misogynistic abuse is why trans people are losing public support.
This persistent misogynistic abuse is why trans people are losing public support.
trans women are women, enshrined by law
animals like you don't get to police if they get to use public spaces, you lost that in 1946
animals like you don't get to police if they get to use public spaces, you lost that in 1946
December 9, 2025 at 12:27 PM
Sorry, lads, it's not a convincing argument to say trans women are women but women defending their hard-won legal rights are animals.
This persistent misogynistic abuse is why trans people are losing public support.
This persistent misogynistic abuse is why trans people are losing public support.