Chris Pook
@drchrispook.bsky.social
Biochemistry, mass spectrometry, metabolomics, chromatography, health, nutrition, physiology, chemoinformatics, computational mass spec. Personal account. #SexMatters #SexNotGender https://thepoliticalerasureofsex.org/
https://projectnettie.wordpress.com/
https://projectnettie.wordpress.com/
Pinned
Chris Pook
@drchrispook.bsky.social
· Dec 18
Polar metabolomics using trichloroacetic acid extraction and porous graphitic carbon stationary phase - Metabolomics
Introduction Accurately identifying and quantifying polar metabolites using untargeted metabolomics has proven challenging in comparison to mid to non-polar metabolites. Hydrophilic interaction chroma...
link.springer.com
It's here! "Polar metabolomics using trichloroacetic acid extraction and porous graphitic carbon stationary phase". The 2nd paper from Frankie Day's PhD & 1 of only 3 in the literature applying porous graphitic carbon stationary phase for #Metabolomics.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
I love tweets like this. Mind blowing.
The protein concentration in the cytoplasm is so high that the average protein has a water hydration shell with a thickness of only ≈ 10 water molecules separating it from the adjacent protein hydration shell.
1/2
1/2
November 11, 2025 at 8:42 AM
I love tweets like this. Mind blowing.
Yup. See also: Aotearoa New Zealand.
Good morning to all those people who wasted the last decade saying, "there's no point tackling climate change in the UK, because China."
www.theguardian.com/world/2025/n...
www.theguardian.com/world/2025/n...
China’s CO2 emissions have been flat or falling for past 18 months, analysis finds
World’s biggest polluter on track to hit peak emissions target early but miss goal for cutting carbon intensity
www.theguardian.com
November 11, 2025 at 8:36 AM
Yup. See also: Aotearoa New Zealand.
Reposted by Chris Pook
Aotearoa is home to almost 28,000 species found nowhere else on Earth. To fast-track hazardous chemicals in New Zealand — as BusinessNZ is proposing — risks this unique biodiversity, the health of our communities, and our reputation as an exporter.
buff.ly/jDtzHME
#hazardouschemicals
#nzepa
buff.ly/jDtzHME
#hazardouschemicals
#nzepa
The Post
buff.ly
November 10, 2025 at 11:30 PM
Aotearoa is home to almost 28,000 species found nowhere else on Earth. To fast-track hazardous chemicals in New Zealand — as BusinessNZ is proposing — risks this unique biodiversity, the health of our communities, and our reputation as an exporter.
buff.ly/jDtzHME
#hazardouschemicals
#nzepa
buff.ly/jDtzHME
#hazardouschemicals
#nzepa
Brilliant news. All men to be banned from women's olympic sports. The gross sexism of Aotearoa New Zealand featuring prominently in the header image.
www.thetimes.com/article/b168...
www.thetimes.com/article/b168...
Transgender women to be banned from all female Olympic events
IOC likely to announce new policy early in new year after findings of a scientific review about the permanent physical advantages of being born male
www.thetimes.com
November 10, 2025 at 6:24 PM
Brilliant news. All men to be banned from women's olympic sports. The gross sexism of Aotearoa New Zealand featuring prominently in the header image.
www.thetimes.com/article/b168...
www.thetimes.com/article/b168...
Reposted by Chris Pook
Human fetal tissue research has saved millions of lives and continues to drive biomedical innovation. Restricting it would not alter abortion rates, it would force scientists to discard an irreplaceable research resource for treating devastating diseases.
Restrictions on fetal tissue research would threaten progress on breakthrough treatments for devastating diseases — and yet not prevent a single abortion
The U.S. government may restrict funding for research that uses human fetal tissue. The move would undermine medical science and prolong patients' suffering from devastating diseases.
www.livescience.com
November 9, 2025 at 1:30 AM
Human fetal tissue research has saved millions of lives and continues to drive biomedical innovation. Restricting it would not alter abortion rates, it would force scientists to discard an irreplaceable research resource for treating devastating diseases.
Reposted by Chris Pook
A deeply misleading book review in Nature implies that the modern view of evolution is woefully incomplete, making the same tired arguments refuted over a decade ago. Moreover, the author of the book review is a collaborator with several of the book's authors.
whyevolutionistrue.com/2025/11/09/n...
whyevolutionistrue.com/2025/11/09/n...
November 9, 2025 at 4:03 PM
A deeply misleading book review in Nature implies that the modern view of evolution is woefully incomplete, making the same tired arguments refuted over a decade ago. Moreover, the author of the book review is a collaborator with several of the book's authors.
whyevolutionistrue.com/2025/11/09/n...
whyevolutionistrue.com/2025/11/09/n...
Today's example of the post-truth society.
‘They contend that the policy “reinforces the gender stereotype that men are more dangerous than women.”’
let’s have a look at the data shall we
let’s have a look at the data shall we
Male Drivers Sue Uber and Lyft Over Women-Only Ride-Hailing
The lawsuits allege that male drivers receive fewer rides because of the feature, violating sex discrimination laws.
time.com
November 9, 2025 at 7:19 PM
Today's example of the post-truth society.
Reposted by Chris Pook
Toilets and bathrooms are sex segregated, not “gendered”, because that is the important factor for safety, privacy, dignity etc, especially for women and girls.
Arguing, as you do here, that women can’t have boundaries because enforcing them is harmful to men, is rape culture.
Arguing, as you do here, that women can’t have boundaries because enforcing them is harmful to men, is rape culture.
November 4, 2025 at 2:03 PM
Toilets and bathrooms are sex segregated, not “gendered”, because that is the important factor for safety, privacy, dignity etc, especially for women and girls.
Arguing, as you do here, that women can’t have boundaries because enforcing them is harmful to men, is rape culture.
Arguing, as you do here, that women can’t have boundaries because enforcing them is harmful to men, is rape culture.
Reposted by Chris Pook
"a true 'commons' for journal-agnostic preprint peer review" www.embo.org/features/pub...
Publishers join the Review Commons peer review process – Features – EMBO
Editors from eLife, Genetics, G3 and Journal of Cell Biology will contribute to the EMBO preprint peer review platform
www.embo.org
November 5, 2025 at 10:17 PM
"a true 'commons' for journal-agnostic preprint peer review" www.embo.org/features/pub...
It's been a long time coming. Huge credit to @elisabethbik.bsky.social as one of the unsung heroines of this shift. I'm sorry I missed your talk in Auckland on Monday.
Paradigm Shift in Monoclonal Protein Detection: From Electrophoresis-based to Mass Spectrometry–based Methods #AnnLabMed www.annlabmed.org/journal/view...
Paradigm Shift in Monoclonal Protein Detection: From Electrophoresis-based to Mass Spectrometry–based Methods
Jikyo Lee, M.D., Sangmi Yoo, B.S., Seojin Yang, B.S., and Sang Hoon Song, M.D., Ph.D.. Ann Lab Med -0001;0:. https://doi.org/10.3343/alm.2025.0133
www.annlabmed.org
November 6, 2025 at 12:09 AM
It's been a long time coming. Huge credit to @elisabethbik.bsky.social as one of the unsung heroines of this shift. I'm sorry I missed your talk in Auckland on Monday.
Another custard apple! 🍏🤤
November 5, 2025 at 7:21 PM
Another custard apple! 🍏🤤
Good morning, blue sky. 😁🌺🌺
November 5, 2025 at 7:08 PM
Good morning, blue sky. 😁🌺🌺
Incredibly gratifying to see the responses to this gross misogyny here on bluesky. #TERFIsland
My letter in the Guardian about why the Equality and Human Rights Commission's guidance on sex and gender is unworkable and goes far beyond what the Supreme Court judgement actually said.
November 5, 2025 at 7:01 PM
Incredibly gratifying to see the responses to this gross misogyny here on bluesky. #TERFIsland
Why There Are Exactly Two Sexes - Archives of Sexual Behavior
Archives of Sexual Behavior -
link.springer.com
November 5, 2025 at 6:47 PM
Reposted by Chris Pook
Colin Wright calls attention to a new paper arguing that advancing your ideology should take precedence over promulgating empirical truth.
whyevolutionistrue.com/2025/11/04/c...
whyevolutionistrue.com/2025/11/04/c...
November 4, 2025 at 5:04 PM
Colin Wright calls attention to a new paper arguing that advancing your ideology should take precedence over promulgating empirical truth.
whyevolutionistrue.com/2025/11/04/c...
whyevolutionistrue.com/2025/11/04/c...
Reposted by Chris Pook
Wellington City Council wants your teenage daughters to get changed in front of men.
Here's my latest in which I question why women were not consulted on the plan to end female changing rooms and toilets in Wellington city. theministryhasfallen.substack.com/p/wccs-rainb...
November 4, 2025 at 6:50 AM
Wellington City Council wants your teenage daughters to get changed in front of men.
This sounds amazing. I'm so glad that *someone* out there is working on this.
This is part of the reason that I’m working on a fully open-source MS instrument. It’s targeted for atmospheric monitoring rather than proteomics, but it’s a step toward making MS hardware much more accessible. Hoping to have it ready to unveil at ASMS 2026.
November 3, 2025 at 10:34 PM
This sounds amazing. I'm so glad that *someone* out there is working on this.
Reposted by Chris Pook
Australians all, please sign this petition!
www.senatorchandler.com.au/back-biologi...
www.senatorchandler.com.au/back-biologi...
SIGN THE PETITION TO REMIND THE GOVERNMENT WHAT A MAN AND A WOMAN ARE
www.senatorchandler.com.au
November 3, 2025 at 9:26 PM
Australians all, please sign this petition!
www.senatorchandler.com.au/back-biologi...
www.senatorchandler.com.au/back-biologi...
Reposted by Chris Pook
Air pollution is a potent neurotoxin. It harms the brains of children & adults. It even harms the brains of babies before birth. Burning fossil fuels is the leading preventable cause of death and ill health in the world today. Clean energy now!
@docsforclimate.bsky.social
@gchalliance.bsky.social
@docsforclimate.bsky.social
@gchalliance.bsky.social
What the Air You Breathe May Be Doing to Your Brain
www.nytimes.com
November 2, 2025 at 12:15 AM
Air pollution is a potent neurotoxin. It harms the brains of children & adults. It even harms the brains of babies before birth. Burning fossil fuels is the leading preventable cause of death and ill health in the world today. Clean energy now!
@docsforclimate.bsky.social
@gchalliance.bsky.social
@docsforclimate.bsky.social
@gchalliance.bsky.social
Reposted by Chris Pook
Stunning illustration of mimicry! Common cuckoo eggs (top row) imitate the eggs of their host species (bottom row). The 30 October issue of Science explains this dazzling coevolution with genomic data — though I admit, it’s complex enough that I’d struggle to teach it! 🧪🌿🌎🦉
November 1, 2025 at 8:42 PM
Stunning illustration of mimicry! Common cuckoo eggs (top row) imitate the eggs of their host species (bottom row). The 30 October issue of Science explains this dazzling coevolution with genomic data — though I admit, it’s complex enough that I’d struggle to teach it! 🧪🌿🌎🦉
I am fortunate enough to live in one of the most beautiful places on the planet. Yesterday we explored the #Piha Blowhole, which lead to this stunning beach between Kaiwhare Point and Takatū Head.
November 2, 2025 at 7:51 PM
I am fortunate enough to live in one of the most beautiful places on the planet. Yesterday we explored the #Piha Blowhole, which lead to this stunning beach between Kaiwhare Point and Takatū Head.
Reposted by Chris Pook
One gene can code for proteoforms with:
◼️ different functions
◼️ different sequences
◼️ different regulation
◼️ different cell type expression
Such examples should inform the interpretation of gene deletion experiments seeking to infer "gene functions".
◼️ different functions
◼️ different sequences
◼️ different regulation
◼️ different cell type expression
Such examples should inform the interpretation of gene deletion experiments seeking to infer "gene functions".
November 1, 2025 at 1:51 PM
One gene can code for proteoforms with:
◼️ different functions
◼️ different sequences
◼️ different regulation
◼️ different cell type expression
Such examples should inform the interpretation of gene deletion experiments seeking to infer "gene functions".
◼️ different functions
◼️ different sequences
◼️ different regulation
◼️ different cell type expression
Such examples should inform the interpretation of gene deletion experiments seeking to infer "gene functions".
Reposted by Chris Pook
