Daniel Bachurski
@danielbachurski.bsky.social
Physician-scientist @unicologne @MSSOabcd @GSEVorg • #CLL and #tumormicroenvironment • passionate about #extracellularvesicles and #masscytometry
ORCID: orcid.org/0000-0001-9168-9680
Google Scholar: scholar.google.com/citations?user=JOFsXzYAAAAJ&hl=de
ORCID: orcid.org/0000-0001-9168-9680
Google Scholar: scholar.google.com/citations?user=JOFsXzYAAAAJ&hl=de
Pinned
Single recipient cell tracking of tellurium-labeled extracellular vesicle proteomes (TeLEV) identifies EV-driven immunomodulation
Extracellular vesicles (EVs) mediate tumor-immune cell communication by carrying protein cargo that can immediately modulate signaling and antigen presentation. Yet mapping the uptake of primary EV pr...
www.biorxiv.org
Excited to share that TeLEV is now live! Our preprint introduces a new method to track #extracellularvesicle (EV) proteomes in single cells using advanced techniques. TeLEV reveals insights into an interleukin receptor triad and immune remodeling. Huge thanks to all collaborators! Preprint here:
Excited to share that TeLEV is now live! Our preprint introduces a new method to track #extracellularvesicle (EV) proteomes in single cells using advanced techniques. TeLEV reveals insights into an interleukin receptor triad and immune remodeling. Huge thanks to all collaborators! Preprint here:
Single recipient cell tracking of tellurium-labeled extracellular vesicle proteomes (TeLEV) identifies EV-driven immunomodulation
Extracellular vesicles (EVs) mediate tumor-immune cell communication by carrying protein cargo that can immediately modulate signaling and antigen presentation. Yet mapping the uptake of primary EV pr...
www.biorxiv.org
November 4, 2025 at 6:56 AM
Excited to share that TeLEV is now live! Our preprint introduces a new method to track #extracellularvesicle (EV) proteomes in single cells using advanced techniques. TeLEV reveals insights into an interleukin receptor triad and immune remodeling. Huge thanks to all collaborators! Preprint here:
Our illustration of immune cell-derived #extracellularvesicles (EVs) in B-cell malignancies is on the cover of FEBS Letters' "Biology of B-cell Malignancies".
We discuss how novel techniques enhance understanding of cell communication in the tumor-immune environment. doi.org/10.1002/1873...
We discuss how novel techniques enhance understanding of cell communication in the tumor-immune environment. doi.org/10.1002/1873...
November 1, 2025 at 7:28 PM
Our illustration of immune cell-derived #extracellularvesicles (EVs) in B-cell malignancies is on the cover of FEBS Letters' "Biology of B-cell Malignancies".
We discuss how novel techniques enhance understanding of cell communication in the tumor-immune environment. doi.org/10.1002/1873...
We discuss how novel techniques enhance understanding of cell communication in the tumor-immune environment. doi.org/10.1002/1873...
Reposted by Daniel Bachurski
🔬 Extracellular vesicles shape immune crosstalk in B-cell malignancies—but remain elusive. Explore the latest insights from new single-EV & single-cell tools: febs.onlinelibrary.wiley.com/doi/10.1002/...
#EVs #CancerResearch #BCellLymphoma @danielbachurski.bsky.social
#EVs #CancerResearch #BCellLymphoma @danielbachurski.bsky.social
July 29, 2025 at 9:12 AM
🔬 Extracellular vesicles shape immune crosstalk in B-cell malignancies—but remain elusive. Explore the latest insights from new single-EV & single-cell tools: febs.onlinelibrary.wiley.com/doi/10.1002/...
#EVs #CancerResearch #BCellLymphoma @danielbachurski.bsky.social
#EVs #CancerResearch #BCellLymphoma @danielbachurski.bsky.social
Reposted by Daniel Bachurski
“Europe’s success depends on treating #science and #research as tools for competitiveness and on recognising them as foundational to Europe’s long-term strategy” erc.europa.eu/news-events/... @erc.europa.eu
Editorial - A stronger Europe starts with science
As leaders from industry, policy and science gathered in Brussels for a lively exchange this spring, o
erc.europa.eu
July 13, 2025 at 9:26 AM
“Europe’s success depends on treating #science and #research as tools for competitiveness and on recognising them as foundational to Europe’s long-term strategy” erc.europa.eu/news-events/... @erc.europa.eu
In recent years, we have developed tools to gain deeper insights into #extracellularvesicle immune cell interactions in B-cell malignancies. We have learned a lot and want to share our perspective: doi.org/10.1002/1873...
FEBS Press
Click on the article title to read more.
doi.org
July 4, 2025 at 5:45 PM
In recent years, we have developed tools to gain deeper insights into #extracellularvesicle immune cell interactions in B-cell malignancies. We have learned a lot and want to share our perspective: doi.org/10.1002/1873...
Reposted by Daniel Bachurski
Reposted by Daniel Bachurski
GSEV POST-ISEV 2025 webinar
2 Jun 2025 · 15:00 CEST · Zoom
Recap of #ISEV2025 with Eva-Maria Krämer-Albers, Allegra Angenendt, Lisa Wessendorf, Fanni Borros + wrap-up team.
Register ➜ fau.zoom-x.de/webinar/regi...
#GSEV #EVresearch #extracellularvesicles
2 Jun 2025 · 15:00 CEST · Zoom
Recap of #ISEV2025 with Eva-Maria Krämer-Albers, Allegra Angenendt, Lisa Wessendorf, Fanni Borros + wrap-up team.
Register ➜ fau.zoom-x.de/webinar/regi...
#GSEV #EVresearch #extracellularvesicles
May 16, 2025 at 2:49 PM
GSEV POST-ISEV 2025 webinar
2 Jun 2025 · 15:00 CEST · Zoom
Recap of #ISEV2025 with Eva-Maria Krämer-Albers, Allegra Angenendt, Lisa Wessendorf, Fanni Borros + wrap-up team.
Register ➜ fau.zoom-x.de/webinar/regi...
#GSEV #EVresearch #extracellularvesicles
2 Jun 2025 · 15:00 CEST · Zoom
Recap of #ISEV2025 with Eva-Maria Krämer-Albers, Allegra Angenendt, Lisa Wessendorf, Fanni Borros + wrap-up team.
Register ➜ fau.zoom-x.de/webinar/regi...
#GSEV #EVresearch #extracellularvesicles
Reposted by Daniel Bachurski
Pretty cool study showing the effect of acid sphingomyelinase on non-coding RNA cargo of MCF-7 EVs.
Big changes in 'miscRNAs' 7SL and Y3 RNA, and functional effects in wound healing
www.sciencedirect.com/science/arti...
Big changes in 'miscRNAs' 7SL and Y3 RNA, and functional effects in wound healing
www.sciencedirect.com/science/arti...
Inhibition of acid or neutral sphingomyelinases differentially impacts RNA and protein cargo sorting to extracellular vesicles
Extracellular vesicles (EVs) form through regulated biogenesis processes involving sphingomyelinases (SMases), enzymes that metabolize sphingomyelin t…
www.sciencedirect.com
May 15, 2025 at 12:52 PM
Pretty cool study showing the effect of acid sphingomyelinase on non-coding RNA cargo of MCF-7 EVs.
Big changes in 'miscRNAs' 7SL and Y3 RNA, and functional effects in wound healing
www.sciencedirect.com/science/arti...
Big changes in 'miscRNAs' 7SL and Y3 RNA, and functional effects in wound healing
www.sciencedirect.com/science/arti...
Reposted by Daniel Bachurski
New @nejm.org
Another win for semaglutide (Ozempic) and the GLP-1 drugs: reduction of liver fibrosis in MASH
www.nejm.org/doi/full/10....
Another win for semaglutide (Ozempic) and the GLP-1 drugs: reduction of liver fibrosis in MASH
www.nejm.org/doi/full/10....
Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis | NEJM
Semaglutide, a glucagon-like peptide-1 receptor agonist, is a candidate for the treatment
of metabolic dysfunction–associated steatohepatitis (MASH). In this ongoing phase
3, multicenter, randomize...
www.nejm.org
April 30, 2025 at 10:05 PM
New @nejm.org
Another win for semaglutide (Ozempic) and the GLP-1 drugs: reduction of liver fibrosis in MASH
www.nejm.org/doi/full/10....
Another win for semaglutide (Ozempic) and the GLP-1 drugs: reduction of liver fibrosis in MASH
www.nejm.org/doi/full/10....
Reposted by Daniel Bachurski
April 27, 2025 at 10:54 AM
Off to Vienna for #ISEV2025! Two projects from the Hallek Lab @unicologne.bsky.social:
– #TeLEV single‑cell EV profiling in CLL (Poster 410, Session 1, Apr 24)
– MULTI-TeLEV: Multiplexed EV uptake assay (OS22, Apr 26 14:30)
Excited to co-chair OS22 with @frederikverweij.bsky.social. DM to connect!
– #TeLEV single‑cell EV profiling in CLL (Poster 410, Session 1, Apr 24)
– MULTI-TeLEV: Multiplexed EV uptake assay (OS22, Apr 26 14:30)
Excited to co-chair OS22 with @frederikverweij.bsky.social. DM to connect!
April 22, 2025 at 8:36 AM
Off to Vienna for #ISEV2025! Two projects from the Hallek Lab @unicologne.bsky.social:
– #TeLEV single‑cell EV profiling in CLL (Poster 410, Session 1, Apr 24)
– MULTI-TeLEV: Multiplexed EV uptake assay (OS22, Apr 26 14:30)
Excited to co-chair OS22 with @frederikverweij.bsky.social. DM to connect!
– #TeLEV single‑cell EV profiling in CLL (Poster 410, Session 1, Apr 24)
– MULTI-TeLEV: Multiplexed EV uptake assay (OS22, Apr 26 14:30)
Excited to co-chair OS22 with @frederikverweij.bsky.social. DM to connect!
Reposted by Daniel Bachurski
👉 Join us for the #GSEV PubQuiz at #ISEV2025 in Vienna!
🗓️ April 26 | 🕕 5:45–7:15 PM | 📍 Room Schubert 4–6
🎯 Fame, glory, free drinks + snacks, and prizes!
🚨 Max 100 spots — first come, first served!
🔗 gsev.org/gsev-pubquiz-at-isev2025/
🗓️ April 26 | 🕕 5:45–7:15 PM | 📍 Room Schubert 4–6
🎯 Fame, glory, free drinks + snacks, and prizes!
🚨 Max 100 spots — first come, first served!
🔗 gsev.org/gsev-pubquiz-at-isev2025/
April 7, 2025 at 7:57 AM
👉 Join us for the #GSEV PubQuiz at #ISEV2025 in Vienna!
🗓️ April 26 | 🕕 5:45–7:15 PM | 📍 Room Schubert 4–6
🎯 Fame, glory, free drinks + snacks, and prizes!
🚨 Max 100 spots — first come, first served!
🔗 gsev.org/gsev-pubquiz-at-isev2025/
🗓️ April 26 | 🕕 5:45–7:15 PM | 📍 Room Schubert 4–6
🎯 Fame, glory, free drinks + snacks, and prizes!
🚨 Max 100 spots — first come, first served!
🔗 gsev.org/gsev-pubquiz-at-isev2025/
Reposted by Daniel Bachurski
🚨 Registration & abstract submission now open!
Join us at GSEV 2025, Sept 25–26 in Essen.
🔗 gsev.org/gsev-2025-au...
Topics: EV biogenesis, standardization, cancer, neuro & cardio disease, immunity & more.
Submit abstracts by May 31 (oral) / Jul 31 (poster)
#GSEV2025 #extracellularvesicles
Join us at GSEV 2025, Sept 25–26 in Essen.
🔗 gsev.org/gsev-2025-au...
Topics: EV biogenesis, standardization, cancer, neuro & cardio disease, immunity & more.
Submit abstracts by May 31 (oral) / Jul 31 (poster)
#GSEV2025 #extracellularvesicles
GSEV 2025 – Autumn Meeting – GSEV
gsev.org
April 2, 2025 at 8:03 AM
🚨 Registration & abstract submission now open!
Join us at GSEV 2025, Sept 25–26 in Essen.
🔗 gsev.org/gsev-2025-au...
Topics: EV biogenesis, standardization, cancer, neuro & cardio disease, immunity & more.
Submit abstracts by May 31 (oral) / Jul 31 (poster)
#GSEV2025 #extracellularvesicles
Join us at GSEV 2025, Sept 25–26 in Essen.
🔗 gsev.org/gsev-2025-au...
Topics: EV biogenesis, standardization, cancer, neuro & cardio disease, immunity & more.
Submit abstracts by May 31 (oral) / Jul 31 (poster)
#GSEV2025 #extracellularvesicles
Why should scientists remain apolitical (especially in times like these)?
February 10, 2025 at 4:30 PM
Why should scientists remain apolitical (especially in times like these)?
Reposted by Daniel Bachurski
Hello, Bluesky! ☀️
We fund frontier research in Europe—bold ideas, unexpected discoveries and science that shapes the future. So it’s only fitting we’ve landed here. Sorry for being late.
Follow us for updates on ERC funding, research policy, and our grantees' discoveries.
We fund frontier research in Europe—bold ideas, unexpected discoveries and science that shapes the future. So it’s only fitting we’ve landed here. Sorry for being late.
Follow us for updates on ERC funding, research policy, and our grantees' discoveries.
February 7, 2025 at 8:16 AM
Hello, Bluesky! ☀️
We fund frontier research in Europe—bold ideas, unexpected discoveries and science that shapes the future. So it’s only fitting we’ve landed here. Sorry for being late.
Follow us for updates on ERC funding, research policy, and our grantees' discoveries.
We fund frontier research in Europe—bold ideas, unexpected discoveries and science that shapes the future. So it’s only fitting we’ve landed here. Sorry for being late.
Follow us for updates on ERC funding, research policy, and our grantees' discoveries.
Reposted by Daniel Bachurski
Not all tRNA fragments (tDRs) are created equal. Here we share methods to differentiate:
1) real tDRs and those produced by dissociation of nicked tRNAs, 2) nicked tRNAs / tDRs in extracellular vesicles vs outside.
1) www.sciencedirect.com/science/arti...
2) www.sciencedirect.com/science/arti...
1) real tDRs and those produced by dissociation of nicked tRNAs, 2) nicked tRNAs / tDRs in extracellular vesicles vs outside.
1) www.sciencedirect.com/science/arti...
2) www.sciencedirect.com/science/arti...
February 1, 2025 at 4:00 PM
Not all tRNA fragments (tDRs) are created equal. Here we share methods to differentiate:
1) real tDRs and those produced by dissociation of nicked tRNAs, 2) nicked tRNAs / tDRs in extracellular vesicles vs outside.
1) www.sciencedirect.com/science/arti...
2) www.sciencedirect.com/science/arti...
1) real tDRs and those produced by dissociation of nicked tRNAs, 2) nicked tRNAs / tDRs in extracellular vesicles vs outside.
1) www.sciencedirect.com/science/arti...
2) www.sciencedirect.com/science/arti...
Reposted by Daniel Bachurski
Review @natrevimmunol.bsky.social @laurenrodda.bsky.social @georgecelis.bsky.social
B cells in non-lymphoid tissues
www.nature.com/articles/s41...
B cells in non-lymphoid tissues
www.nature.com/articles/s41...
B cells in non-lymphoid tissues - Nature Reviews Immunology
B cells are major drivers of systemic immunity, but they also act locally in non-lymphoid organs. This Review highlights new insights into mechanisms of tissue B cell function as well as efforts to le...
www.nature.com
February 6, 2025 at 2:03 AM
Review @natrevimmunol.bsky.social @laurenrodda.bsky.social @georgecelis.bsky.social
B cells in non-lymphoid tissues
www.nature.com/articles/s41...
B cells in non-lymphoid tissues
www.nature.com/articles/s41...
Reposted by Daniel Bachurski
"Dark proteins." Also known as microproteins. There are thousands of them in our cells and we're still struggling to define their function. Succinctly reviewed @nature.com www.nature.com/articles/d41...
‘Dark proteins’ hiding in our cells could hold clues to cancer and other diseases
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do.
www.nature.com
February 1, 2025 at 4:42 PM
"Dark proteins." Also known as microproteins. There are thousands of them in our cells and we're still struggling to define their function. Succinctly reviewed @nature.com www.nature.com/articles/d41...
Reposted by Daniel Bachurski
This rate of validation suggests that antibodies should be considered non-specific until proven otherwise:
357 validated out of 1,124 tested.
.
357 validated out of 1,124 tested.
.
January 31, 2025 at 12:24 PM
This rate of validation suggests that antibodies should be considered non-specific until proven otherwise:
357 validated out of 1,124 tested.
.
357 validated out of 1,124 tested.
.
Reposted by Daniel Bachurski
EU medicines agency quits X & moves to Bluesky
"EMA will no longer post updates and content on X. We believe the X platform no longer suits our communication needs” the agency said in a statement
www.reuters.com/world/europe...
"EMA will no longer post updates and content on X. We believe the X platform no longer suits our communication needs” the agency said in a statement
www.reuters.com/world/europe...
EU medicines agency quits X, moves to Bluesky
The European Medicines Agency (EMA) said on Monday it would no longer post on X and would use rival Bluesky instead, becoming the latest organisation to quit a social media platform that some have criticised for its content.
www.reuters.com
January 27, 2025 at 6:36 PM
EU medicines agency quits X & moves to Bluesky
"EMA will no longer post updates and content on X. We believe the X platform no longer suits our communication needs” the agency said in a statement
www.reuters.com/world/europe...
"EMA will no longer post updates and content on X. We believe the X platform no longer suits our communication needs” the agency said in a statement
www.reuters.com/world/europe...
Reposted by Daniel Bachurski
The conference report on the joint meeting of ASEV and our sister community CzeSEV is online at #EVCNA 😍
www.oaepublish.com/articles/evc...
www.oaepublish.com/articles/evc...
A comprehensive summary of the ASEV-CzeSEV joint meeting on extracellular vesicles
This report summarizes the ASEV-CzeSEV Joint Meeting on Extracellular Vesicles (EVs), held at the Medical University of Vienna in September 2024. The conference focused on introducing and expanding EV...
www.oaepublish.com
January 27, 2025 at 4:00 PM
The conference report on the joint meeting of ASEV and our sister community CzeSEV is online at #EVCNA 😍
www.oaepublish.com/articles/evc...
www.oaepublish.com/articles/evc...
Reposted by Daniel Bachurski
Your input matters! Help shape the future of the @gsevorg.bsky.social by sharing what you value and what’s missing. Your feedback will guide us in advancing collaborative German #extracellularvesicle research in 2025. Take 2-3 minutes to complete our survey: docs.google.com/forms/d/1zA8...
GSEV Survey 2025
It's feedback time! Please take 2-3 minutes to fill this survey and take the opportunity to shape GSEV according to your needs. The results will be presented on the next GSEV member's meeting on March...
docs.google.com
January 26, 2025 at 12:09 PM
Your input matters! Help shape the future of the @gsevorg.bsky.social by sharing what you value and what’s missing. Your feedback will guide us in advancing collaborative German #extracellularvesicle research in 2025. Take 2-3 minutes to complete our survey: docs.google.com/forms/d/1zA8...
Reposted by Daniel Bachurski
Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X
https://go.nature.com/42tH8Ai
https://go.nature.com/42tH8Ai
Bluesky’s science takeover: 70% of Nature poll respondents use platform
Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X.
go.nature.com
January 24, 2025 at 11:52 AM
Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X
https://go.nature.com/42tH8Ai
https://go.nature.com/42tH8Ai
Reposted by Daniel Bachurski
Check out the brand new @gsevorg.bsky.social
January 2025 Newsletter! Explore EV research updates, upcoming events in 2025 (IGLD/GSEV Spring Meeting, GSEV Autumn Meeting, new calls for MOVE scholarships), and more. Join us in advancing #extracellularvesicle research.
➡️http://gsev.org
January 2025 Newsletter! Explore EV research updates, upcoming events in 2025 (IGLD/GSEV Spring Meeting, GSEV Autumn Meeting, new calls for MOVE scholarships), and more. Join us in advancing #extracellularvesicle research.
➡️http://gsev.org
January 24, 2025 at 6:32 PM
Check out the brand new @gsevorg.bsky.social
January 2025 Newsletter! Explore EV research updates, upcoming events in 2025 (IGLD/GSEV Spring Meeting, GSEV Autumn Meeting, new calls for MOVE scholarships), and more. Join us in advancing #extracellularvesicle research.
➡️http://gsev.org
January 2025 Newsletter! Explore EV research updates, upcoming events in 2025 (IGLD/GSEV Spring Meeting, GSEV Autumn Meeting, new calls for MOVE scholarships), and more. Join us in advancing #extracellularvesicle research.
➡️http://gsev.org
Reposted by Daniel Bachurski
CD45-PET is a robust, non-invasive tool for imaging inflammation
@nature.com @alisalehifarid.bsky.social
www.nature.com/articles/s41...
@nature.com @alisalehifarid.bsky.social
www.nature.com/articles/s41...
January 22, 2025 at 6:02 PM
CD45-PET is a robust, non-invasive tool for imaging inflammation
@nature.com @alisalehifarid.bsky.social
www.nature.com/articles/s41...
@nature.com @alisalehifarid.bsky.social
www.nature.com/articles/s41...