Here is a summary 🧵
“Pericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature”
This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia!
🔗 www.biorxiv.org/content/10.1...
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“Pericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature”
This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia!
🔗 www.biorxiv.org/content/10.1...
🧪 🧵1/8
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
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We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
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For our "Integrative physiological considerations of the human vasculature system" #SpecialIssue, which will showcase further insights into vascular haemodynamics and multi-organ diseases, as well as the technology used to monitor and treat cardiovascular disease.
🔗 buff.ly/HN7wlPr
For our "Integrative physiological considerations of the human vasculature system" #SpecialIssue, which will showcase further insights into vascular haemodynamics and multi-organ diseases, as well as the technology used to monitor and treat cardiovascular disease.
🔗 buff.ly/HN7wlPr
👇 Curious to hear more about #PrecapillarySphincters?
Check out these threads about the subject:
Characterization: x.com/SorenGrubb/s...
Ultrastructure: x.com/SorenGrubb/s...
👇 Curious to hear more about #PrecapillarySphincters?
Check out these threads about the subject:
Characterization: x.com/SorenGrubb/s...
Ultrastructure: x.com/SorenGrubb/s...
KI mouse expressing red fluorescent blood
In situ SpyTag/Catcher attachment of biosensor
ECS SpyCatcher to capture BBB leak
doi.org/10.1101/2025...
We hope this method is useful to a wide range of the biology community.
KI mouse expressing red fluorescent blood
In situ SpyTag/Catcher attachment of biosensor
ECS SpyCatcher to capture BBB leak
doi.org/10.1101/2025...
We hope this method is useful to a wide range of the biology community.
Whisker stim in Sorcs2 KO 🐭 led to ⬇️NVC, ⬇️astrocyte Ca²⁺ signals & disrupted glutamate receptor trafficking.
Whisker stim in Sorcs2 KO 🐭 led to ⬇️NVC, ⬇️astrocyte Ca²⁺ signals & disrupted glutamate receptor trafficking.
Thanks to Vicki Hinkley for such a productive partnership—I’m excited to continue this collaboration across 🇩🇰 and 🇦🇺. I’m also grateful to the USC CONNECT Programme for the funding 🙏
Thanks to Vicki Hinkley for such a productive partnership—I’m excited to continue this collaboration across 🇩🇰 and 🇦🇺. I’m also grateful to the USC CONNECT Programme for the funding 🙏
New paper by Christian Aalkjaer et al in @actaphysiologica.bsky.social 🔓: onlinelibrary.wiley.com/doi/full/10....
🦒 While drinking🚰:
⬇️ Heart rate
➡️ Arterial blood pressure
➡️ Carotid blood flow
⬆️ CSF pressure 🧠
New paper by Christian Aalkjaer et al in @actaphysiologica.bsky.social 🔓: onlinelibrary.wiley.com/doi/full/10....
🦒 While drinking🚰:
⬇️ Heart rate
➡️ Arterial blood pressure
➡️ Carotid blood flow
⬆️ CSF pressure 🧠
We'll dive into #EM, #inVivo #physiology, behavioural analysis tools, and a talk on creating animations from open data! @quorumetrix.bsky.social
📢 Free for NorDoc PhD students, but open to all! Apply now!
lnkd.in/dU_fxqqu
We'll dive into #EM, #inVivo #physiology, behavioural analysis tools, and a talk on creating animations from open data! @quorumetrix.bsky.social
📢 Free for NorDoc PhD students, but open to all! Apply now!
lnkd.in/dU_fxqqu
KI mouse expressing red fluorescent blood
In situ SpyTag/Catcher attachment of biosensor
ECS SpyCatcher to capture BBB leak
doi.org/10.1101/2025...
We hope this method is useful to a wide range of the biology community.
A potential role of Glycine in GSH antioxidant & #Inflammasome in #SmoothMuscleCell
#SignalTransductTargetTher 2025
www.nature.com/articles/s41...
A potential role of Glycine in GSH antioxidant & #Inflammasome in #SmoothMuscleCell
#SignalTransductTargetTher 2025
www.nature.com/articles/s41...
A powerful step toward automated and scalable morphology analysis.
#AI #neuroimmunology #cardiacarrest
A powerful step toward automated and scalable morphology analysis.
#AI #neuroimmunology #cardiacarrest
A powerful step toward automated and scalable morphology analysis.
#AI #neuroimmunology #cardiacarrest
A powerful step toward automated and scalable morphology analysis.
#AI #neuroimmunology #cardiacarrest
Brain Arterial #EndothelialCell BKca & TRPV4 (immunofluorescence)⏫by acute (0.5~2 h) #Hypoxia or #Stroke across🐁🐀🐖🚶♂️
@chrstaehr.bsky.social #ActaPhysiol 2025
onlinelibrary.wiley.com/doi/10.1111/...
Brain Arterial #EndothelialCell BKca & TRPV4 (immunofluorescence)⏫by acute (0.5~2 h) #Hypoxia or #Stroke across🐁🐀🐖🚶♂️
@chrstaehr.bsky.social #ActaPhysiol 2025
onlinelibrary.wiley.com/doi/10.1111/...
#BBB #cerebrovascular #neurosky #emedsky #medsky
🧪
Molecular drivers of mural cell hyperconstriction & BBB disintegration in post-stroke futile reperfusion?
A dual non-neuronal role of Calcineurin?
@chrstaehr.bsky.social #Stroke 2025
www.ahajournals.org/doi/10.1161/...
#ionchannels #vascularbiology #physiology #cerebrovascular #endothelium #neurosky #emedsky #medsky
#ionchannels #vascularbiology #physiology #cerebrovascular #endothelium #neurosky #emedsky #medsky
Molecular drivers of mural cell hyperconstriction & BBB disintegration in post-stroke futile reperfusion?
A dual non-neuronal role of Calcineurin?
@chrstaehr.bsky.social #Stroke 2025
www.ahajournals.org/doi/10.1161/...
Molecular drivers of mural cell hyperconstriction & BBB disintegration in post-stroke futile reperfusion?
A dual non-neuronal role of Calcineurin?
@chrstaehr.bsky.social #Stroke 2025
www.ahajournals.org/doi/10.1161/...
#microcirculation #science
#microcirculation #science
Truly appreciate the leadership of @rrust.bsky.social on this great project (>300 refs!)🫡👇
The blood–brain barrier: a help & a hindrance
#Aging #Stroke #Neurodegeneration
Crossing #BBB 😎
academic.oup.com/brain/advanc...
Truly appreciate the leadership of @rrust.bsky.social on this great project (>300 refs!)🫡👇
The blood–brain barrier: a help & a hindrance
#Aging #Stroke #Neurodegeneration
Crossing #BBB 😎
academic.oup.com/brain/advanc...
@brain1878.bsky.social
We explore how molecular blood-brain barrier (BBB) changes in aging, neurodegeneration and stroke affect disease progression, delivery of therapeutics, and much more!
academic.oup.com/brain/advanc...
@brain1878.bsky.social
We explore how molecular blood-brain barrier (BBB) changes in aging, neurodegeneration and stroke affect disease progression, delivery of therapeutics, and much more!
academic.oup.com/brain/advanc...