Boris Zinshteyn
@bzinsh.bsky.social
RNA Biologist. Bioinformatician. Philadelphian.
Reposted by Boris Zinshteyn
October 11, 2025 at 11:19 PM
Reposted by Boris Zinshteyn
MADELEINE DEAN: The president is unhinged. He's unwell
JOHNSON: A lot of folks on your side are too
D: Oh my god, please. That performance in front of the generals?
J: I didn't see it
D: It's so dangerous! Our allies are looking elsewhere. Our enemies are laughing. You have a POTUS who's unwell.
JOHNSON: A lot of folks on your side are too
D: Oh my god, please. That performance in front of the generals?
J: I didn't see it
D: It's so dangerous! Our allies are looking elsewhere. Our enemies are laughing. You have a POTUS who's unwell.
October 2, 2025 at 12:40 AM
MADELEINE DEAN: The president is unhinged. He's unwell
JOHNSON: A lot of folks on your side are too
D: Oh my god, please. That performance in front of the generals?
J: I didn't see it
D: It's so dangerous! Our allies are looking elsewhere. Our enemies are laughing. You have a POTUS who's unwell.
JOHNSON: A lot of folks on your side are too
D: Oh my god, please. That performance in front of the generals?
J: I didn't see it
D: It's so dangerous! Our allies are looking elsewhere. Our enemies are laughing. You have a POTUS who's unwell.
Reposted by Boris Zinshteyn
You asked for it! We delivered Quack-O-Grams to our members of Congress urging them to #ImpeachRFK, and get that Quack out of office!
There's still time for you to get in on this fluffy, feathery action: Send your own duck at zurl.co/W1ZnB and keep the momentum going! 🦆
There's still time for you to get in on this fluffy, feathery action: Send your own duck at zurl.co/W1ZnB and keep the momentum going! 🦆
September 17, 2025 at 9:34 PM
You asked for it! We delivered Quack-O-Grams to our members of Congress urging them to #ImpeachRFK, and get that Quack out of office!
There's still time for you to get in on this fluffy, feathery action: Send your own duck at zurl.co/W1ZnB and keep the momentum going! 🦆
There's still time for you to get in on this fluffy, feathery action: Send your own duck at zurl.co/W1ZnB and keep the momentum going! 🦆
Reposted by Boris Zinshteyn
THE VIDEO IS HERE!!!
You asked for it! We delivered Quack-O-Grams to our members of Congress urging them to #ImpeachRFK, and get that Quack out of office!
There's still time for you to get in on this fluffy, feathery action: Send your own duck at zurl.co/W1ZnB and keep the momentum going! 🦆
There's still time for you to get in on this fluffy, feathery action: Send your own duck at zurl.co/W1ZnB and keep the momentum going! 🦆
September 17, 2025 at 9:36 PM
THE VIDEO IS HERE!!!
Reposted by Boris Zinshteyn
🐤Promise you this is one you'll want to say you were a part of...
Help us get our 'ducks in a row' and IMPEACH AND REMOVE THAT DANG QUACK!!!! 📣🦆📣🦆📣🦆📣🦆
Link here: tinyurl.com/sufsci
Help us get our 'ducks in a row' and IMPEACH AND REMOVE THAT DANG QUACK!!!! 📣🦆📣🦆📣🦆📣🦆
Link here: tinyurl.com/sufsci
August 21, 2025 at 6:00 PM
🐤Promise you this is one you'll want to say you were a part of...
Help us get our 'ducks in a row' and IMPEACH AND REMOVE THAT DANG QUACK!!!! 📣🦆📣🦆📣🦆📣🦆
Link here: tinyurl.com/sufsci
Help us get our 'ducks in a row' and IMPEACH AND REMOVE THAT DANG QUACK!!!! 📣🦆📣🦆📣🦆📣🦆
Link here: tinyurl.com/sufsci
Reposted by Boris Zinshteyn
🚨ACTION OF THE DAY🚨
@standupforscience.bsky.social
Day 21! QUACK-O-GRAM THURSDAY!
For $3 we will hand deliver an "IMPEACH THE QUACK" rubber ducky to your House Representative! (By one of our team members in a duck suit!)
DO IT (AND TELL YOUR FRIENDS)
act.standupforscience.net/fundraising/...
@standupforscience.bsky.social
Day 21! QUACK-O-GRAM THURSDAY!
For $3 we will hand deliver an "IMPEACH THE QUACK" rubber ducky to your House Representative! (By one of our team members in a duck suit!)
DO IT (AND TELL YOUR FRIENDS)
act.standupforscience.net/fundraising/...
August 21, 2025 at 1:47 PM
🚨ACTION OF THE DAY🚨
@standupforscience.bsky.social
Day 21! QUACK-O-GRAM THURSDAY!
For $3 we will hand deliver an "IMPEACH THE QUACK" rubber ducky to your House Representative! (By one of our team members in a duck suit!)
DO IT (AND TELL YOUR FRIENDS)
act.standupforscience.net/fundraising/...
@standupforscience.bsky.social
Day 21! QUACK-O-GRAM THURSDAY!
For $3 we will hand deliver an "IMPEACH THE QUACK" rubber ducky to your House Representative! (By one of our team members in a duck suit!)
DO IT (AND TELL YOUR FRIENDS)
act.standupforscience.net/fundraising/...
Reposted by Boris Zinshteyn
Via @standupforscience.bsky.social
Join us in pressuring all in the House to IMPEACH AND REMOVE RFK Jr. We'll hand-deliver a rubber ducky with your IMPEACH THE QUACK message to YOUR House Rep.
Of course I did it. $3 well-spent.
act.standupforscience.net/fundraising/...
Join us in pressuring all in the House to IMPEACH AND REMOVE RFK Jr. We'll hand-deliver a rubber ducky with your IMPEACH THE QUACK message to YOUR House Rep.
Of course I did it. $3 well-spent.
act.standupforscience.net/fundraising/...
Help power the Summer Fight For Science movement!
Donate now to help mobilize the fight for science and democracy. Every contribution matters!
act.standupforscience.net
August 21, 2025 at 1:37 PM
Via @standupforscience.bsky.social
Join us in pressuring all in the House to IMPEACH AND REMOVE RFK Jr. We'll hand-deliver a rubber ducky with your IMPEACH THE QUACK message to YOUR House Rep.
Of course I did it. $3 well-spent.
act.standupforscience.net/fundraising/...
Join us in pressuring all in the House to IMPEACH AND REMOVE RFK Jr. We'll hand-deliver a rubber ducky with your IMPEACH THE QUACK message to YOUR House Rep.
Of course I did it. $3 well-spent.
act.standupforscience.net/fundraising/...
Reposted by Boris Zinshteyn
“What a [sunburned] cell is trying to do is make decisions about whether to live or die based on how damaged the DNA is… but amazingly, it’s the RNA that signals that. That’s the remarkable observation.” — Rachel Green, biologist at Johns Hopkins University.
www.quantamagazine.org/rna-is-the-c...
www.quantamagazine.org/rna-is-the-c...
August 4, 2025 at 8:04 PM
“What a [sunburned] cell is trying to do is make decisions about whether to live or die based on how damaged the DNA is… but amazingly, it’s the RNA that signals that. That’s the remarkable observation.” — Rachel Green, biologist at Johns Hopkins University.
www.quantamagazine.org/rna-is-the-c...
www.quantamagazine.org/rna-is-the-c...
Reposted by Boris Zinshteyn
“we reviewed the science, listened to the experts, and completely ignored it all because we are fuckin dumbasses who want millions of people to die”
"The U.S. Department of Health and Human Services (HHS) today announced the beginning of a coordinated wind-down of its mRNA vaccine development activities...."
cc: Sen. Bill Cassidy
cc: Sen. Bill Cassidy
August 5, 2025 at 11:43 PM
“we reviewed the science, listened to the experts, and completely ignored it all because we are fuckin dumbasses who want millions of people to die”
Reposted by Boris Zinshteyn
Mitch McConnell, shown here busily de-funding NIH research on childhood cancers,
Look at the scowl on Susan Collins' face - she will sabotage any effort to protect our world class medical research. On November 3, 2026 we have the chance to purge the Senate of this mendacious traitor by flipping her seat to a Dem.
bsky.app/profile/stan...
bsky.app/profile/stan...
“To the scientists wondering if there will even be an NIH by the end of this administration, this committee’s resounding message is: ‘Yes, Congress has your back’,” said @murray.senate.gov
We’re not near the finish line yet - but this is a strong step in the right direction.
zurl.co/AzSK7
We’re not near the finish line yet - but this is a strong step in the right direction.
zurl.co/AzSK7
August 6, 2025 at 12:16 AM
Mitch McConnell, shown here busily de-funding NIH research on childhood cancers,
Reposted by Boris Zinshteyn
BREAKING NEWS: a government watchdog confirmed the Trump administration is breaking the law by blocking NIH funds.
How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?
Trump must end this illegal funding freeze.
How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?
Trump must end this illegal funding freeze.
August 5, 2025 at 10:46 PM
BREAKING NEWS: a government watchdog confirmed the Trump administration is breaking the law by blocking NIH funds.
How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?
Trump must end this illegal funding freeze.
How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?
Trump must end this illegal funding freeze.
Reposted by Boris Zinshteyn
Our RAPPL purification of ribosomes and associated material is out. I am really proud of this study in collaboration primary with Pavlovic-Djuranovic lab, as well as Jovanovic and Hashem Labs. This method aims to replace 60 years old purification of ribosomes by sucrose cushions
rdcu.be/ezlhg
rdcu.be/ezlhg
A rapid, simple, and economical method for the isolation of ribosomes and translational machinery for structural and functional studies
Nature Communications - Here, the authors present a method to rapidly isolate actively translating ribosomes in a time- and cost-effective manner using poly-lysine. The method is compatible with a...
rdcu.be
August 5, 2025 at 1:19 PM
Our RAPPL purification of ribosomes and associated material is out. I am really proud of this study in collaboration primary with Pavlovic-Djuranovic lab, as well as Jovanovic and Hashem Labs. This method aims to replace 60 years old purification of ribosomes by sucrose cushions
rdcu.be/ezlhg
rdcu.be/ezlhg
Reposted by Boris Zinshteyn
If you think a golden ballroom is more important than childhood cancer research… I have nothing left to say to you. Please unfollow me.
#pediatriccancer #cancermom
#pediatriccancer #cancermom
August 5, 2025 at 9:40 PM
If you think a golden ballroom is more important than childhood cancer research… I have nothing left to say to you. Please unfollow me.
#pediatriccancer #cancermom
#pediatriccancer #cancermom
Reposted by Boris Zinshteyn
Here’s the truth: vaccines save lives.
This National Immunization Awareness Month, please join me in the fight to protect access to vaccines and reverse Trump's cuts to critical immunization research.
This National Immunization Awareness Month, please join me in the fight to protect access to vaccines and reverse Trump's cuts to critical immunization research.
August 5, 2025 at 10:30 PM
Here’s the truth: vaccines save lives.
This National Immunization Awareness Month, please join me in the fight to protect access to vaccines and reverse Trump's cuts to critical immunization research.
This National Immunization Awareness Month, please join me in the fight to protect access to vaccines and reverse Trump's cuts to critical immunization research.
Reposted by Boris Zinshteyn
my lab needs a repeat pipetter that can dispense 1ml 12 times. (can be analog or digital). i've never had one of these- does anyone have one to recommend?
(pls reski)
(pls reski)
August 5, 2025 at 12:25 PM
my lab needs a repeat pipetter that can dispense 1ml 12 times. (can be analog or digital). i've never had one of these- does anyone have one to recommend?
(pls reski)
(pls reski)
Reposted by Boris Zinshteyn
The #BethesdaDeclaration signers killed it today during the roundtable with Jay.
Some of my favorite highlights shared from my colleagues:
🧵 1/5
Some of my favorite highlights shared from my colleagues:
🧵 1/5
July 22, 2025 at 3:20 AM
The #BethesdaDeclaration signers killed it today during the roundtable with Jay.
Some of my favorite highlights shared from my colleagues:
🧵 1/5
Some of my favorite highlights shared from my colleagues:
🧵 1/5
Reposted by Boris Zinshteyn
"Jim Kent knew a thing or two about coding." Yes. And he knew a thing or two about splicing as well, like using ESTs to jump across gaps. It's one way you turn "chopped genome salad" into a useful draft.
Congrats on 25 years! A product of the golden age of US science funding. 💪
Congrats on 25 years! A product of the golden age of US science funding. 💪
After a quarter of a century, the UCSC Genome Browser remains an essential tool for navigating the genome and understanding its structure, function and clinical impact
https://go.nature.com/40wPxkB
https://go.nature.com/40wPxkB
’We couldn’t live without it’: the UCSC Genome Browser turns 25
After a quarter of a century, the website remains an essential tool for navigating the genome and understanding its structure, function and clinical impact.
go.nature.com
June 30, 2025 at 2:28 PM
"Jim Kent knew a thing or two about coding." Yes. And he knew a thing or two about splicing as well, like using ESTs to jump across gaps. It's one way you turn "chopped genome salad" into a useful draft.
Congrats on 25 years! A product of the golden age of US science funding. 💪
Congrats on 25 years! A product of the golden age of US science funding. 💪
Reposted by Boris Zinshteyn
After a quarter of a century, the UCSC Genome Browser remains an essential tool for navigating the genome and understanding its structure, function and clinical impact
https://go.nature.com/40wPxkB
https://go.nature.com/40wPxkB
’We couldn’t live without it’: the UCSC Genome Browser turns 25
After a quarter of a century, the website remains an essential tool for navigating the genome and understanding its structure, function and clinical impact.
go.nature.com
June 30, 2025 at 11:49 AM
After a quarter of a century, the UCSC Genome Browser remains an essential tool for navigating the genome and understanding its structure, function and clinical impact
https://go.nature.com/40wPxkB
https://go.nature.com/40wPxkB
Reposted by Boris Zinshteyn
This is an excellent article on the termination of all federal funding at Harvard.
This visualization shows all of the terminated programs that were supposed to train the next generation of scientists.
www.nytimes.com/interactive/...
This visualization shows all of the terminated programs that were supposed to train the next generation of scientists.
www.nytimes.com/interactive/...
June 23, 2025 at 9:19 PM
This is an excellent article on the termination of all federal funding at Harvard.
This visualization shows all of the terminated programs that were supposed to train the next generation of scientists.
www.nytimes.com/interactive/...
This visualization shows all of the terminated programs that were supposed to train the next generation of scientists.
www.nytimes.com/interactive/...
Reposted by Boris Zinshteyn
"The money the government sends to Harvard is, in effect, not a subsidy to advance the university’s mission. It’s a payment for the role Harvard plays in advancing the research mission of the United States." www.nytimes.com/interactive/...
Here Is All the Science at Risk in Trump’s Clash With Harvard (Gift Article)
More than 900 research grants worth $2.6 billion are in jeopardy. So is the 80-year-old model of American science.
www.nytimes.com
June 23, 2025 at 6:48 PM
"The money the government sends to Harvard is, in effect, not a subsidy to advance the university’s mission. It’s a payment for the role Harvard plays in advancing the research mission of the United States." www.nytimes.com/interactive/...
Reposted by Boris Zinshteyn
🚨 BREAKING: Nearly 4 months the NIH cut its first grants, a judge has ruled that the directives and process that led to cuts are arbitrary and capricious.
"The explanations are bereft of reasoning — virtually in their entirety... unsupported by [facts]."
Each of them are VOID and ILLEGAL, he says.
"The explanations are bereft of reasoning — virtually in their entirety... unsupported by [facts]."
Each of them are VOID and ILLEGAL, he says.
June 16, 2025 at 6:16 PM
🚨 BREAKING: Nearly 4 months the NIH cut its first grants, a judge has ruled that the directives and process that led to cuts are arbitrary and capricious.
"The explanations are bereft of reasoning — virtually in their entirety... unsupported by [facts]."
Each of them are VOID and ILLEGAL, he says.
"The explanations are bereft of reasoning — virtually in their entirety... unsupported by [facts]."
Each of them are VOID and ILLEGAL, he says.
Reposted by Boris Zinshteyn
Since we featured the Stand Up for Science letter in the Good Trouble segment of the Daily Beans podcast this morning, signatures have gone from roughly 5,000 to 15,000! You can add your name by clicking the link below:
“We are compelled to speak up when our leadership prioritizes political momentum over human safety and faithful stewardship of public resources.”
Bravo to the brave folks at NIH who published the Bethesda Declaration this morning to hold this administration accountable! You can sign a letter…
Bravo to the brave folks at NIH who published the Bethesda Declaration this morning to hold this administration accountable! You can sign a letter…
Bethesda Declaration — STAND UP FOR SCIENCE
Support NIH Staff Now!
www.standupforscience.net
June 10, 2025 at 8:45 PM
Since we featured the Stand Up for Science letter in the Good Trouble segment of the Daily Beans podcast this morning, signatures have gone from roughly 5,000 to 15,000! You can add your name by clicking the link below:
Reposted by Boris Zinshteyn
Please sign on and add your voice in calling for an NIH that prioritizes the safety of research participants and public health over political momentum.
actionnetwork.org/forms/add-na...
actionnetwork.org/forms/add-na...
ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff
Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.
actionnetwork.org
June 10, 2025 at 4:10 AM
Please sign on and add your voice in calling for an NIH that prioritizes the safety of research participants and public health over political momentum.
actionnetwork.org/forms/add-na...
actionnetwork.org/forms/add-na...
Reposted by Boris Zinshteyn
I've been thinking a lot about the history of RNA biology, and which lines of inquiry got lost to the vagaries of time vs. followed up on. Fun find along the way: this model of a tRNA built by then first year undergraduate Elizabeth Cavicchi @mit.edu
mitmuseum.mit.edu/collections/...
mitmuseum.mit.edu/collections/...
June 2, 2025 at 3:51 PM
I've been thinking a lot about the history of RNA biology, and which lines of inquiry got lost to the vagaries of time vs. followed up on. Fun find along the way: this model of a tRNA built by then first year undergraduate Elizabeth Cavicchi @mit.edu
mitmuseum.mit.edu/collections/...
mitmuseum.mit.edu/collections/...
Reposted by Boris Zinshteyn
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
May 22, 2025 at 12:42 PM
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.