Brady Johnston
bradyajohnston.bsky.social
Brady Johnston
@bradyajohnston.bsky.social
Scientific animator, structural biologist, creator of #MolecularNodes bradyajohnston.github.io/MolecularNodes/
Reposted by Brady Johnston
Your go-to tutorial for simulating mesoscale membranes is here. Look no further for:
-Understanding the state of the field
-A guide for creating new models for your science
-Hands-on tutorials to simulate your very own membranes
See tinyurl.com/punk3tcu and the below 🧵 start your journey 💻
October 22, 2025 at 2:21 PM
Reposted by Brady Johnston
Bringing invisible ideas to life.

#sciart #blender3D #illustration

*illustrations created for Mary Munson’s Lab website at UMass Chan Medical School*
October 1, 2025 at 8:32 AM
Reposted by Brady Johnston
I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5)
doi.org/10.1101/2025.09.24.678028 #proteindesign
September 28, 2025 at 9:16 PM
Reposted by Brady Johnston
Also, shoutout to @blender.org and @bradyajohnston.bsky.social for making it so easy to turn protein structures into nice images!
5/5
September 24, 2025 at 12:27 PM
Reposted by Brady Johnston
so proud to share @jhuapl.bsky.social neuroscience research at #blenderconference2025 @blender.org ❤️

also shoutout to #microscopynodes by @aafkegros.bsky.social, here's to awesome new collabs born at blendercon!!!
Blending brains: Tales from the neuro department — Blender Conference 2025
YouTube video by Blender
youtu.be
September 19, 2025 at 11:47 AM
Reposted by Brady Johnston
Hello! I'm Behnoush, structural biology scientist from the Broad Institute. I also like to combine proteins structures and other scientific topics with art. Here are some journal cover arts I've created recently. Hope to find old and new friends here.
#Blender #b3d #MolecularNodes #GeometryNodes
September 19, 2025 at 7:28 PM
Reposted by Brady Johnston
New video about caffeine linked here:
youtu.be/fNR-GY-WoAI

Rendered in #blender3d using @bradyajohnston.bsky.social 's brilliant Molecular Nodes extension.

Make sure you check out the incredible coffee from @thegooddotstore.bsky.social 's Keats & Co by visiting keats.watchclockwork.com
The Incredible Biology Powering Caffeine
YouTube video by Clockwork
youtu.be
September 16, 2025 at 7:15 PM
Reposted by Brady Johnston
What's the opposite of Artificial Intelligence? Naturally Occurring Stupidity?

Whatever it is, that's what I'm here for!

Check out my new film here - made with love, by humans, for humans: youtu.be/iNMxVBnIrwQ

#animation #shortfilm #blender #b3d
September 2, 2025 at 2:58 PM
Reposted by Brady Johnston
RosettaFold 3 is here! 🧬🚀

AtomWorks (the foundational data pipeline powering it) is perhaps the really most exciting part of this release!

Congratulations @simonmathis.bsky.social and team!!! ❤️

bioRxiv preprint: www.biorxiv.org/content/10.1...
August 15, 2025 at 1:26 PM
Reposted by Brady Johnston
Thrilled to share my first corresponding author paper as a project leader in @hillerlab.bsky.social ‪ Amazing work from first author @annaleder.bsky.social We discovered multi-chaperone condensates in the ER that revolutionise the current vision of protein folding!
www.nature.com/articles/s41...
August 11, 2025 at 10:14 AM
Reposted by Brady Johnston
🕒 NEW VIDEO 🕒

How can a cell know the time? Let's explore the beautiful 24-hour cycle produced by #KaiC proteins in the cyanobacteria S. Elongatus. Rendered in #blender3d with @bradyajohnston.bsky.social's brilliant Molecular Nodes add-on. #biology
August 5, 2025 at 4:00 PM
Reposted by Brady Johnston
Thrilled to see our study on how kinesin-2 motors are switched on and off published in @natsmb.nature.com ⚛️

➡️ www.nature.com/articles/s41...

Congrats to all authors from me and Anthony 🎉 @dunnschool.bsky.social Check out this animation made by talented PhD student @matthew-batisio.bsky.social 😆
July 29, 2025 at 9:04 AM
Reposted by Brady Johnston
Today is #StructureSunday, where we highlight awesome structures by our @arc_gov_au CCeMMP members 🎉 Today we feature the "The structure of h12-LOX in hexameric form" by Mobbs et al. PDB 8GHD. 📷 Rendered using #Blender 📷 🤩1/2
July 20, 2025 at 3:16 AM
Reposted by Brady Johnston
pay us £1500 for the privilege of doing our graphic design work for free
July 16, 2025 at 2:06 PM
Reposted by Brady Johnston
Happy to share our latest work on the structure and assembly of holocentric kinetochores! Huge thanks to Ines for a very fruitful collaboration, Claudio for all the support, and congratulations to Christine and all co-authors!

www.biorxiv.org/content/10.1...
July 15, 2025 at 4:36 PM
Reposted by Brady Johnston
What’s New in Geometry Nodes in Blender 4.5 #b3d #geometrynodes youtu.be/qc38O52EQqQ
What's New in Geometry Nodes in Blender 4.5
YouTube video by harry blends
youtu.be
July 15, 2025 at 2:03 PM
Reposted by Brady Johnston
We have a new position going at the UWA OceanOmics Centre - level 5 bioinformatics research officer. Should suit a MSc-level graduate
external.jobs.uwa.edu.au/cw/en/job/52...
Work with TONS of fish genomes, and most of the genomics data out there - Revio, PromethION, Illumina
#bioinformatics
Prospective staff : Jobs at UWA : The University Of Western Australia
external.jobs.uwa.edu.au
July 14, 2025 at 1:22 AM
Reposted by Brady Johnston
Excited to share our latest work using AI-designed proteins to block heme-piracy by E. coli. Published in @natcomms.nature.com. A team effort between my lab and the ‪‪@knottrna.bsky.social‬ ‬lab, with experimental work led by the talented @danielrfox.bsky.social
www.nature.com/articles/s41...
Inhibiting heme piracy by pathogenic Escherichia coli using de novo-designed proteins - Nature Communications
Many pathogens encode transporters that extract heme directly from host proteins. In this study, the authors demonstrate the utility of de novo-designed proteins in understanding the mechanism behind ...
www.nature.com
July 9, 2025 at 11:55 PM
Playing around with ligands and emission lighting #MolecularNodes #GeometryNodes #b3d #motm #SciArt
July 8, 2025 at 6:38 PM
Reposted by Brady Johnston
In our latest preprint on bioRxiv, we present the in situ structure of
the human gap junction at 14 Å resolution using cryo-ET.

The structure provides a blueprint for investigating how connexin
regulation shapes intercellular communication in health and disease.
July 8, 2025 at 5:33 AM
Reposted by Brady Johnston
Now that AI LLMs can use tools via MCP, how long before LLMs get wrapped in tools so other AIs can talk to them? An AI agent could end up talking to itself via a long game of telephone.
May 25, 2025 at 10:45 AM
Reposted by Brady Johnston
#mdaUGM2025 is officially happening! Abstracts and travel bursary applications are being accepted from now until the July 15, 2025 deadline: www.mdanalysis.org/2025/04/13/u....

🗓️ November 9-11, 2025
📍Tempe, Arizona, USA (and online)

#open-source-software #molecular #simulations #streaming
May 20, 2025 at 6:24 PM
Reposted by Brady Johnston
The average American has three friends:
May 2, 2025 at 1:40 PM
Reposted by Brady Johnston
I wrote a document describing how we want to make it possible to build high level and easy-to-use node group assets for physics simulations and more. #b3d #devfund #GeometryNodes

devtalk.blender.org/t/declarativ...
Declarative Systems in Geometry Nodes
Currently, one of our primary goals for Geometry Nodes is to get to a point where we can build high level and easy to use node group assets for physics simulations. Our general approach was described…
devtalk.blender.org
May 1, 2025 at 6:43 AM
Reposted by Brady Johnston
New paper out in Nature Communications from @natureportfolio.nature.com :
We present #GōMartini 3 — combining structure-based Gōwith #Martini3 to better capture #protein conformational changes and environmental effects.

📄 www.nature.com/articles/s41...
GōMartini 3: From large conformational changes in proteins to environmental bias corrections - Nature Communications
This work presents GōMartini 3, an improved coarse-grained protein model combining physics- and structure-based approaches. It boosts computational efficiency and accuracy for structured soluble and m...
www.nature.com
April 30, 2025 at 10:03 PM