Development release of version 2.0.0 for public testing Code is fully migrated to .NET 8, thus, Mono dependency is obsolete Added an action for automatic building and testing on all code changes A...

Apply now for Archaeology Lab Technician at Durham University, UK. Full-time permanent role in Archaeology. Deadline: 17 Sept 2025.

15-17 December 2025 Dept. Evolutionary Biology, Ecology & Environmental Sciences Faculty of Biology, University of Barcelona Institut de Recerca de la Biodiversitat (IRBio) Av. Diagonal, 643, Les ...

SMBE 2026 Symposia Check deadlines and important dates below.  Days Hours Minutes Seconds Conference Symposia We are now accepting proposals for symposium for the 2026 Annual meeting taking place in Copenhagen, Denmark. Selection of proposals will prioritize the interests of SMBE members, emphasizing innovative scientific developments while ensuring geographic and gender diversity among the participants. […]

YouTube video by PAASTA community

Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00179

Microbiome; Omics; Proteomics; Archeology

In his critique of economics, as in his philippic against ‘bullshit jobs’, Graeber stresses the political decisions...

FragPipe is recognized as one of the fastest computational platforms in proteomics, making it a practical solution for the rapid quality control of high-throughput sample analyses. Starting with version 23.0, FragPipe introduced the “Generate Summary Report” feature, offering .pdf reports with essential quality control metrics to address the challenge of intuitively assessing large-scale proteomics data. While traditional spreadsheet formats (e.g., tsv files) are accessible, the complexity of the data often limits user-friendly interpretation. To further enhance accessibility, PSManalyst, a Shiny-based R application, was developed to process FragPipe output files (psm.tsv, protein.tsv, and combined_protein.tsv) and provide interactive, code-free data visualization. Users can filter peptide-spectrum matches (PSMs) by quality scores, visualize protease cleavage fingerprints as heatmaps and SeqLogos, and access a range of quality control metrics and representations such as peptide length distributions, ion densities, mass errors, and wordclouds for overrepresented peptides. The tool facilitates seamless switching between PSM and protein data visualization, offering insights into protein abundance discrepancies, samplewise similarity metrics, protein coverage, and contaminants evaluation. PSManalyst leverages several R libraries (lsa, vegan, ggfortify, ggseqlogo, wordcloud2, tidyverse, ggpointdensity, and plotly) and runs on Windows, MacOS, and Linux, requiring only a local R setup and an IDE. The app is available at (https://github.com/41ison/PSManalyst.

Listen and download Diálogos Sapiens - Sapiens Dialogues episodes for free. 22nd episode of Sapiens Dialogues. This is the fourth dialogue of the fourth season. The paleoproteomics specialist Prof. Ma...