Tobias Kroniger
@kronigert.bsky.social
I work as a Field Application Scientist at Bruker. I'm interested in coffee, sports, science and a lot of leg space. Views are my own. he/him. #Proteomics #TeamMassSpec
Pinned
Struggling to compare Bruker timsTOF methods or extract window schemes from raw .d files? I developed a free desktop tool to solve this: timsCompare! 🚀
It automates the manual work of extracting method parameters, presenting them in a structured and comparable view.
(A thread 🧵)
It automates the manual work of extracting method parameters, presenting them in a structured and comparable view.
(A thread 🧵)
I just pushed an update to the timsCompare GitHub.
- compiled with Nuitka preventing false-flagging by AV software
- startup parameters can now be customized
- plots can now be resized to the measured mass range
- extraction of used instrument and used timsControl version
github.com/kronigert/ti...
- compiled with Nuitka preventing false-flagging by AV software
- startup parameters can now be customized
- plots can now be resized to the measured mass range
- extraction of used instrument and used timsControl version
github.com/kronigert/ti...
Release timsCompare v1.1 · kronigert/timsCompare
Some people reported false-positive flagging of the tool by some AV softwares. This was due using pyinstaller in the previous build. This version has been compiled with Nuitka and should not be fla...
github.com
October 31, 2025 at 9:59 AM
I just pushed an update to the timsCompare GitHub.
- compiled with Nuitka preventing false-flagging by AV software
- startup parameters can now be customized
- plots can now be resized to the measured mass range
- extraction of used instrument and used timsControl version
github.com/kronigert/ti...
- compiled with Nuitka preventing false-flagging by AV software
- startup parameters can now be customized
- plots can now be resized to the measured mass range
- extraction of used instrument and used timsControl version
github.com/kronigert/ti...
Struggling to compare Bruker timsTOF methods or extract window schemes from raw .d files? I developed a free desktop tool to solve this: timsCompare! 🚀
It automates the manual work of extracting method parameters, presenting them in a structured and comparable view.
(A thread 🧵)
It automates the manual work of extracting method parameters, presenting them in a structured and comparable view.
(A thread 🧵)
October 15, 2025 at 11:01 AM
Struggling to compare Bruker timsTOF methods or extract window schemes from raw .d files? I developed a free desktop tool to solve this: timsCompare! 🚀
It automates the manual work of extracting method parameters, presenting them in a structured and comparable view.
(A thread 🧵)
It automates the manual work of extracting method parameters, presenting them in a structured and comparable view.
(A thread 🧵)
If you're not attending ASMS but are interested in updates from Bruker, you can still take part in the eXceed symposia via livestream.
Register here to join the livestream:
www.bruker.com/en/landingpa...
#ASMS2025 #Bruker #MassSpectrometry #eXceedSymposia
Register here to join the livestream:
www.bruker.com/en/landingpa...
#ASMS2025 #Bruker #MassSpectrometry #eXceedSymposia
ASMS 2025
Join Bruker at ASMS 2025. Experience cutting-edge advancements in mass spectrometry technology as the innovation superheroes come to ASMS 2025.
www.bruker.com
May 27, 2025 at 7:15 AM
If you're not attending ASMS but are interested in updates from Bruker, you can still take part in the eXceed symposia via livestream.
Register here to join the livestream:
www.bruker.com/en/landingpa...
#ASMS2025 #Bruker #MassSpectrometry #eXceedSymposia
Register here to join the livestream:
www.bruker.com/en/landingpa...
#ASMS2025 #Bruker #MassSpectrometry #eXceedSymposia
Reposted by Tobias Kroniger
Job alert 🧪 ‼️ Hi #teammassspec: In our #RTG2467 @unihalle.bsky.social we have a job opening for a PhD student in my group! 🎉 If you want to do cool stuff in cross-linking mass spectrometry of the tumor suppressor p53, please take a look:
personal.verwaltung.uni-halle.de/jobs/wissmi/
Please RT!
personal.verwaltung.uni-halle.de/jobs/wissmi/
Please RT!
Externe Stellenausschreibungen- Wissenschaftliche Mitarbeiterinnen und Mitarbeiter, Ärzte und Lehrkräfte für besondere Aufgaben
personal.verwaltung.uni-halle.de
February 7, 2025 at 10:33 AM
Job alert 🧪 ‼️ Hi #teammassspec: In our #RTG2467 @unihalle.bsky.social we have a job opening for a PhD student in my group! 🎉 If you want to do cool stuff in cross-linking mass spectrometry of the tumor suppressor p53, please take a look:
personal.verwaltung.uni-halle.de/jobs/wissmi/
Please RT!
personal.verwaltung.uni-halle.de/jobs/wissmi/
Please RT!
Reposted by Tobias Kroniger
🧪If you join our lab you will be able to use our three timsTOF mass spectrometers….and we also got a new microwave oven for our lab kitchen today!😜
#ChemSky
#AcademicSky
#ChemSky
#AcademicSky
February 13, 2025 at 4:41 PM
🧪If you join our lab you will be able to use our three timsTOF mass spectrometers….and we also got a new microwave oven for our lab kitchen today!😜
#ChemSky
#AcademicSky
#ChemSky
#AcademicSky
Reposted by Tobias Kroniger
🚀 Robust and high sensitivity #proteomics: Our Nature protocol demystifies #PASEF workflows and provides ready-to-use dia-PASEF & synchro-PASEF methods. Find out how to achieve 7,000 protein groups or 29,000 phosphosites in 21min. Let's explore! #TeamMassSpec #Bruker doi.org/10.1038/s415... 1/🧵
https://doi.org/10.1038/s41596-024-01104-w1/🧵
January 20, 2025 at 8:49 PM
🚀 Robust and high sensitivity #proteomics: Our Nature protocol demystifies #PASEF workflows and provides ready-to-use dia-PASEF & synchro-PASEF methods. Find out how to achieve 7,000 protein groups or 29,000 phosphosites in 21min. Let's explore! #TeamMassSpec #Bruker doi.org/10.1038/s415... 1/🧵
Reposted by Tobias Kroniger
TimsTOF ultra 2 cookies for the group.🍪😋🎄🎄🎄 #teammassspec @brukercorporation.bsky.social
December 15, 2024 at 12:32 PM
TimsTOF ultra 2 cookies for the group.🍪😋🎄🎄🎄 #teammassspec @brukercorporation.bsky.social
Reposted by Tobias Kroniger
@brukercorporation.bsky.social‘s latest app note highlights that ultra-high-throughput proteomics doesn’t have to compromise depth or quality.
Pairing a timsTOF HT with an Aurora Rapid 5x75 column, researchers ID over 7,200 protein groups & 85,658 precursors in 5 mins.
Read: bit.ly/3YWZk27
Pairing a timsTOF HT with an Aurora Rapid 5x75 column, researchers ID over 7,200 protein groups & 85,658 precursors in 5 mins.
Read: bit.ly/3YWZk27
November 25, 2024 at 10:51 AM
@brukercorporation.bsky.social‘s latest app note highlights that ultra-high-throughput proteomics doesn’t have to compromise depth or quality.
Pairing a timsTOF HT with an Aurora Rapid 5x75 column, researchers ID over 7,200 protein groups & 85,658 precursors in 5 mins.
Read: bit.ly/3YWZk27
Pairing a timsTOF HT with an Aurora Rapid 5x75 column, researchers ID over 7,200 protein groups & 85,658 precursors in 5 mins.
Read: bit.ly/3YWZk27
Reposted by Tobias Kroniger
#teamMassSpec here is a starting pack in case you just moved over, or in case you've been absent for a while. This is #proteomics or #massspec related. The pack is not comprehensive but it's a start.
go.bsky.app/HH7kqEh
go.bsky.app/HH7kqEh
November 10, 2024 at 3:46 PM
#teamMassSpec here is a starting pack in case you just moved over, or in case you've been absent for a while. This is #proteomics or #massspec related. The pack is not comprehensive but it's a start.
go.bsky.app/HH7kqEh
go.bsky.app/HH7kqEh
Reposted by Tobias Kroniger
Hi #TeamMassSpec, 👋 good to see everyone on 🦋 side. I am still looking for a PhD-level immunopeptidomics intern for summer 2025 with expected graduation by summer 2026. If you know of any good labs to check with, please let me know! Bruker timsTOF experience is a big plus.
November 13, 2024 at 1:56 AM
Hi #TeamMassSpec, 👋 good to see everyone on 🦋 side. I am still looking for a PhD-level immunopeptidomics intern for summer 2025 with expected graduation by summer 2026. If you know of any good labs to check with, please let me know! Bruker timsTOF experience is a big plus.
Reposted by Tobias Kroniger
diaTracer enables spectrum-centric analysis of diaPASEF proteomics data www.biorxiv.org/cont...
---
#proteomics #prot-preprint
---
#proteomics #prot-preprint
May 30, 2024 at 5:20 PM
diaTracer enables spectrum-centric analysis of diaPASEF proteomics data www.biorxiv.org/cont...
---
#proteomics #prot-preprint
---
#proteomics #prot-preprint
Reposted by Tobias Kroniger
Fragment ion intensity prediction improves the identification rate of non-tryptic peptides in timsTOF - Nature Communications www.nature.com/artic...
---
#proteomics #prot-paper
---
#proteomics #prot-paper
May 11, 2024 at 2:00 PM
Fragment ion intensity prediction improves the identification rate of non-tryptic peptides in timsTOF - Nature Communications www.nature.com/artic...
---
#proteomics #prot-paper
---
#proteomics #prot-paper
Reposted by Tobias Kroniger
Ultra-sensitive metaproteomics (uMetaP) redefines the dark field of metaproteome, enables single-bacterium resolution, and discovers hidden functions in the gut microbiome www.biorxiv.org/cont...
---
#proteomics #prot-preprint
---
#proteomics #prot-preprint
April 23, 2024 at 7:40 AM
Ultra-sensitive metaproteomics (uMetaP) redefines the dark field of metaproteome, enables single-bacterium resolution, and discovers hidden functions in the gut microbiome www.biorxiv.org/cont...
---
#proteomics #prot-preprint
---
#proteomics #prot-preprint
Reposted by Tobias Kroniger
News in Proteomics Research blog post | THUNDER-PASEF - Get those real immunopeptides! proteomicsnews.blogs...
---
#proteomics #prot-other
---
#proteomics #prot-other
March 16, 2024 at 1:40 PM
News in Proteomics Research blog post | THUNDER-PASEF - Get those real immunopeptides! proteomicsnews.blogs...
---
#proteomics #prot-other
---
#proteomics #prot-other
Reposted by Tobias Kroniger
News in Proteomics Research blog post | Need more surfactants for proteomics? Here is a big table! proteomicsnews.blogs...
---
#proteomics #prot-other
---
#proteomics #prot-other
March 12, 2024 at 8:20 AM
News in Proteomics Research blog post | Need more surfactants for proteomics? Here is a big table! proteomicsnews.blogs...
---
#proteomics #prot-other
---
#proteomics #prot-other
Reposted by Tobias Kroniger
Nice to see more tutorial videos out there . m.youtube.com/watch?v=_Om1...
Tutorial Series: Everything You Need to Know About Spectronaut®
Introducing our new #Spectronaut video tutorial series!👩🚀📽️In these tutorials, Monika Puchalska, our Software Product Manager, walks you through everythi...
m.youtube.com
January 10, 2024 at 3:01 PM
Nice to see more tutorial videos out there . m.youtube.com/watch?v=_Om1...
Reposted by Tobias Kroniger
Comprehensive Overview of Bottom-up Proteomics using Mass Spectrometry arxiv.org/abs/2311.0...
---
#proteomics #prot-preprint
---
#proteomics #prot-preprint
November 15, 2023 at 8:20 AM
Comprehensive Overview of Bottom-up Proteomics using Mass Spectrometry arxiv.org/abs/2311.0...
---
#proteomics #prot-preprint
---
#proteomics #prot-preprint
Reposted by Tobias Kroniger
JOB ALERT! We are looking for technical support in our lab! Permanent position! No BS time-limited contracts! Have a look and apply! stellenangebote.uni-marburg.de/jobposting/e...
#marburg #germany #proteomics #laboratory
#marburg #germany #proteomics #laboratory
November 1, 2023 at 7:35 AM
JOB ALERT! We are looking for technical support in our lab! Permanent position! No BS time-limited contracts! Have a look and apply! stellenangebote.uni-marburg.de/jobposting/e...
#marburg #germany #proteomics #laboratory
#marburg #germany #proteomics #laboratory
Reposted by Tobias Kroniger
Our new preprint optimising search parameters in DIA is out. We show DIA can suffer effects similar to match-between runs in DDA, with false positives being detected across runs.
But we offer simple solution that dramatically reduces them while maintaining proteome depth. #proteomics
But we offer simple solution that dramatically reduces them while maintaining proteome depth. #proteomics
Optimising Spectronaut search parameters to improve data quality with minimal proteome coverage reductions in DIA analyses of heterogeneous samples https://www.biorxiv.org/content/10.1101/2023.10.11.561927v1
Optimising Spectronaut search parameters to improve data quality with minimal proteome coverage reductions in DIA analyses of heterogeneous samples https://www.biorxiv.org/content/10.1101/2023.10.11.561927v1
Data independent acquisition has seen breakthroughs that enable comprehensive proteome profiling usi
www.biorxiv.org
October 12, 2023 at 7:06 AM
Our new preprint optimising search parameters in DIA is out. We show DIA can suffer effects similar to match-between runs in DDA, with false positives being detected across runs.
But we offer simple solution that dramatically reduces them while maintaining proteome depth. #proteomics
But we offer simple solution that dramatically reduces them while maintaining proteome depth. #proteomics
Are you interested in the Bruker timsTOF Ultra? Then I am happy to inform you that the Webinar with our Application Development Specialist Christoph Krisp about “Setting and maintaining the single cell proteomics benchmark” is now available on-demand:
www.bruker.com/de/news-and-...
www.bruker.com/de/news-and-...
Setting and maintaining the single cell proteomics benchmark - Meet the timsTOF Ultra
www.bruker.com
October 10, 2023 at 11:18 AM
Are you interested in the Bruker timsTOF Ultra? Then I am happy to inform you that the Webinar with our Application Development Specialist Christoph Krisp about “Setting and maintaining the single cell proteomics benchmark” is now available on-demand:
www.bruker.com/de/news-and-...
www.bruker.com/de/news-and-...