Michael Sinden
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mdsinden.bsky.social
Michael Sinden
@mdsinden.bsky.social
Chief Brand Officer (CBO) at @ionopticks.bsky.social
LC-MS. Chromatography. Tech. Brand. Design.
A big year for us at IonOpticks! It's always nice to look back on a recap like this to see all we've achieved. Hats off to #teamIO who never fail to impress. Your dedication and unrelenting commitment have resulted in a mammoth year of monumental steps forward!
2025 was a remarkable year for IonOpticks, defined by recognition & global reach. Industry awards validated our work, while our growing team strengthened connections with researchers worldwide. We’re proud to expand our impact while staying true to our collaborative spirit. Read our year in review.
2025 in review: A year of recognition, growth, new products, and more people where you need them.
IN THIS EDITION 2025 has come to an end, and, looking back, it’s clear quite quickly what a remarkable year this was for IonOpticks. It’s striking how much has changed in just 12 months.
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December 22, 2025 at 6:47 AM
Reposted by Michael Sinden
What a year it’s been - time to recharge and enjoy a well-earned break. Our office will be closed from December 25th to January 4th and we’ll be back online from Monday, January 5th.

We wish you a safe and festive holiday break. See you in 2026!
December 22, 2025 at 1:06 AM
Reposted by Michael Sinden
The ZenoTOF 8600 paired with Aurora Series columns: a powerful combination showcased by @sciex.bsky.social’s Jean-Baptiste Vincendet at PSI-2025. >10,000 protein group IDs from 250 ng K562 cell line. Eager to see what else researchers achieve as adoption of the ZenoTOF 8600 system continues to grow.
December 22, 2025 at 12:31 AM
Reposted by Michael Sinden
12-lab study shows that DIA methods ID 1.8× more proteins than traditional DDA approaches in plasma analysis, with significantly better reproducibility (5.9% vs 15.4% CV). Distler et al.'s standardised approach brings clinical proteomics closer to accredited diagnostics.

bit.ly/492ZhXk
Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set - IonOpticks
This human plasma benchmark set study by Distler et al. used IonOpticks Aurora Ultimate 25×75 CSI and Aurora Rapid 5x150 CSI UHPLC columns.
bit.ly
December 21, 2025 at 10:32 PM
Reposted by Michael Sinden
TWO WEEKS LEFT: Say yes to every sample with a complimentary 3-pack of NEW NanoShield™ reversed-flush C18 trap columns with every HeatSync™ Starter Pack, and Aurora Series® 5 and 10-pack through December!

Shop online or request a quote: bit.ly/4pPMP44
Promotion ends 11:59pm AEDT December 31, 2025
December 12, 2025 at 2:41 AM
Reposted by Michael Sinden
Zhang et al. develop SPIDR (Single-cell Protein Immobilisation and Digestion tube Reactor), an accessible, high-throughput approach that simplifies single-cell proteomics for resource-limited labs. LC-MS/MS used Aurora Ultimate 25x75 CSI column on nanoElute coupled to timsTOF Pro 2.

bit.ly/44iDR7e
A Simple and Flexible Strategy for Single-Cell Proteomic Analysis Based on Protein Immobilization and Digestion Tube Reactor
Mass spectrometry-based single-cell proteomics (SCP) analysis has witnessed rapid development over the past 10 years. However, the current preprocessing methodologies face several challenges: multiple...
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December 11, 2025 at 10:43 PM
Reposted by Michael Sinden
Please welcome Haley Oller as Field Application Specialist - North America. With over a decade of experience in MS and proteomics, Haley brings technical expertise and a passion for collaborative science. She's excited to support proteomic scientists and help facilitate the next wave of discoveries.
December 11, 2025 at 10:08 PM
Reposted by Michael Sinden
Anyone who’s been to our User Appreciation Events knows how important events are to us, which is why we're thrilled to welcome Annie Ward as our Global Events Manager. Our User Event in Toronto was all Annie - we can’t wait to see how she shapes our upcoming events into unforgettable experiences.
December 8, 2025 at 11:29 PM
Reposted by Michael Sinden
NOW PUBLISHED: An open-source framework, alphaDIA, uses a feature-free approach to process complex spectral data, outperforming existing methods across various platforms.

Samples separated on Aurora Elite 15x75 by Whisper 40SPD method & on Aurora Rapid 8x150 by Whisper 60SPD.

bit.ly/48Go0R9
AlphaDIA enables DIA transfer learning for feature-free proteomics - IonOpticks
This feature-free proteomics study by Wallmann et al. used IonOpticks Aurora Elite 15×75 and Aurora Rapid 8x150 XT UHPLC columns.
bit.ly
December 8, 2025 at 2:20 AM
Reposted by Michael Sinden
Callahan et al. suggest the kinase Itk as a potential target for reducing unwanted CAR activity. Phosphotyrosine-enriched peptides separated with Vanquish Neo & Aurora Ultimate 25x75 column. MS performed on an Orbitrap Ascend.

bit.ly/3Mn9Ugc
Phosphoproteomic analysis of successive Jurkat CD19-CAR generations reveals TCRζ-driven signalling
Although chimeric antigen receptor (CAR) T cell therapy has revolutionised individualised cancer therapies for relapsed/refractory lymphomas, low long…
bit.ly
December 7, 2025 at 10:45 PM
Reposted by Michael Sinden
Get a complimentary 3-pack of NEW NanoShield™ trap columns with every Aurora Series starter pack, 5-pack, or 10-pack. Run every sample confidently, knowing your analytical columns are safeguarded. Start 2026 fully stocked AND protected.

Stock up before December 31, 11:59pm AEST: bit.ly/4pPMP44
December 5, 2025 at 5:50 AM
Reposted by Michael Sinden
It’s been a great start to ITPA 2025 - talking to local customers, getting to know the Italian proteomics community, and the challenges they're facing. Stop by our exhibition booth and chat to Britta to learn more, share your challenges, and explore NanoShield™ with a dedicated new application note.
December 5, 2025 at 4:33 AM
Reposted by Michael Sinden
Recognition is most impactful when it’s consistent and done in a variety of ways. On Friday, we added a whole new way of recognising our people, incorporating IonOpticks' Employee Values Awards into our EOY staff event. Thank you to everyone in the team for making every day at IonOpticks a pleasure.
December 3, 2025 at 4:06 AM
Reposted by Michael Sinden
We kicked off our first user networking event in Montréal, bringing together new and familiar faces from the mass spec community over curated Canadian craft beers. A great turnout, great conversations, and plenty of collaborative energy. We can’t wait to host more events globally.
November 21, 2025 at 11:27 PM
Reposted by Michael Sinden
Yesterday, IonOpticks and SCIEX hosted a hands-on Proteomics in Practice workshop at SCIEX’s Toronto R&D site, giving attendees real-world experience with IonOpticks columns and ZenoTOF systems. Thanks to Tim Heymann, Shelley Jager, Reza Dorvash, Patrick Pribil, Katherine Tran and Jarrod Sandow.
November 14, 2025 at 12:38 PM
Reposted by Michael Sinden
Our latest Application Note with A. Prof. Schoof’s team at DTU showcases the Aurora® Rapid™ 8×75 XT column’s durability: 4000+ injections with consistent, high-quality data on Vanquish Neo + Orbitrap Astral, proving reliability for advanced proteomics research. Read: bit.ly/AuroraRapid8x75Longevity
November 12, 2025 at 4:02 PM
Reposted by Michael Sinden
IonOpticks’ 150 µm Aurora Series® capillary flow range has been named a winner in The Analytical Scientist Top 10 Innovation Awards 2025, recognising our impact in analytical science through smarter workflows and enhanced performance. Read more: bit.ly/IonOpticksTASAward2025
November 12, 2025 at 3:47 PM
Reposted by Michael Sinden
Day two of #HUPO2025 ends with incredible excitement around NanoShield™ - live quotes, pre-orders, and constant conversation confirm its impact on high-value workflows. Grab your #ProteinJunkie merch at booth 603, and don’t miss tomorrow’s User Appreciation Event. Coaches depart 6:15pm.
November 11, 2025 at 9:11 PM
Reposted by Michael Sinden
IonOpticks is expanding its distributor network globally, partnering across APAC, the US, and Europe to bring Aurora Series® columns closer to researchers. This network enables faster delivery, local support, and greater access to the performance that powers discovery.
IonOpticks broadens global reach with new distribution partnerships across APAC
Global leader in the manufacture of high-performance liquid chromatography columns, IonOpticks, today announces a major expansion of its global distribution network, partnering with several leading sc...
ionopticks.com
November 11, 2025 at 3:44 PM
Reposted by Michael Sinden
#HUPO2025 is off to a flying start, with last night’s welcome reception packed with energy and engaging conversations - as well as our largest-ever delegation on the ground here in Toronto.

Drop by booth 603 to meet us and see what’s new.
November 10, 2025 at 5:08 PM
Reposted by Michael Sinden
Congratulations to Momentum Biotechnologies on adding the Orbitrap Astral paired with Aurora Series columns to your analytical arsenal. It's fantastic to see CROs investing in the tools that drive faster turnaround times and superior results for their clients.

Learn more: bit.ly/4nPc7ic
#proteomics #massspectrometry #orbitrapastral #thermofisherscientific #drugdiscovery #drugdevelopment #chemoproteomics | Chromatography & Mass Spectrometry
Join us in Celebrating a Major Milestone with Momentum Biotechnologies! 🎉 A huge congratulations to Momentum Biotechnologies on the addition of the Thermo Scientific™ Orbitrap™ Astral™ mass spectrome...
bit.ly
October 13, 2025 at 2:26 AM
Very proud day! Congrats to our entire team who brought this product to life!
We're proud to announce that IonOpticks has won an Australian Good Design Award for the HeatSync™ Controller. This recognition from one of the longest-running global design awards validates our belief that great analytical tools deserve beautiful, intuitive supporting equipment.

bit.ly/47o8Ikr
October 14, 2025 at 7:27 AM
Reposted by Michael Sinden
With IonOpticks' rapid growth come exciting opportunities to join our expanding global team. We’re looking for passionate people who want to push the boundaries of LC-MS-based research. Ready to be part of an impact-driven company making a real difference in life sciences? Visit bit.ly/4nByJSI
September 22, 2025 at 12:48 AM
I’m hiring (again)! IonOpticks’ Brand & Marketing team is growing fast. Looking for a Marketing and Creative Lead with graphic design skills who thrives across campaigns, content, sales targeting & branding. Careers page for job description: ionopticks.com/careers
September 17, 2025 at 11:38 AM
Reposted by Michael Sinden
IonOpticks expands in Europe with two key appointments: Joris Frenz, PhD as BDM and Dr. Britta Diedrich as Senior BDM. Together they bring scientific and commercial expertise to support DACH/European researchers and boost access to IonOpticks’ leading LC-MS solutions. Read more.
IonOpticks strengthens European operations with key business development appointments.
MELBOURNE, AUSTRALIA | Tuesday August 26, 2025 IonOpticks, a world-leading provider of liquid chromatography solutions, today announces two strategic appointments to expand its European operations, st...
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August 26, 2025 at 10:53 AM