Beth Psaila
@bethpsaila.bsky.social
Professor of Haematology, MRC Weatherall Institute of Molecular Medicine and Ludwig Cancer Research Institute, University of Oxford. All about megs/platelets, myeloid malignancies and the bone marrow microenvironment.
website - https://psailalab.com
website - https://psailalab.com
Pinned
Beth Psaila
@bethpsaila.bsky.social
· Aug 15
Thrilled that our paper is in print @science.org!!
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
‼️See below terrific opportunity for a postdoc post with a leading group in Oxford, super exciting science! 🔥🔥👇
Please share: we’re recruiting a postdoctoral fellow – applications open until September 15!
To lead genomics data analysis of an exciting translational project in sAML cancer, supportive environment, and access to unique in-house technologies.
my.corehr.com/pls/uoxrecru...
To lead genomics data analysis of an exciting translational project in sAML cancer, supportive environment, and access to unique in-house technologies.
my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
September 9, 2025 at 12:16 PM
‼️See below terrific opportunity for a postdoc post with a leading group in Oxford, super exciting science! 🔥🔥👇
thanks for highlighting our study @erictopol.bsky.social !
Platelets sequester and harbor cell-free tumor DNA, which could enhance our ability to make early, microscopic diagnosis of cancer
@science.org
science.org/doi/10.1126/...
science.org/doi/10.1126/...
@science.org
science.org/doi/10.1126/...
science.org/doi/10.1126/...
August 15, 2025 at 5:44 AM
thanks for highlighting our study @erictopol.bsky.social !
Thrilled that our paper is in print @science.org!!
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
August 15, 2025 at 5:37 AM
Thrilled that our paper is in print @science.org!!
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
MPN community (patients/families) - do join us with MPN voice tomorrow if you are interested to hear updates on all the exciting data presented at the recent European Haematology Congress @mpnvoice.bsky.social @mpnrf.bsky.social www.mpnvoice.org.uk/news/mpn-voi...
MPN Voice ‘virtual’ forum – Post EHA 2025 updates Thu 3 July 2025
www.mpnvoice.org.uk
July 2, 2025 at 5:01 PM
MPN community (patients/families) - do join us with MPN voice tomorrow if you are interested to hear updates on all the exciting data presented at the recent European Haematology Congress @mpnvoice.bsky.social @mpnrf.bsky.social www.mpnvoice.org.uk/news/mpn-voi...
Exciting times for mutCALR MPNs - lovely data from the ET cohort presented in late breaking abstract at @EHA_Hematology. Rapid platelet control after just 2 doses with 89% of patients benefitting from a molecular response with INCA033989. @mpnvoice.bsky.social @mpnrf.bsky.social @mpnhv.bsky.social
June 15, 2025 at 8:05 AM
Exciting times for mutCALR MPNs - lovely data from the ET cohort presented in late breaking abstract at @EHA_Hematology. Rapid platelet control after just 2 doses with 89% of patients benefitting from a molecular response with INCA033989. @mpnvoice.bsky.social @mpnrf.bsky.social @mpnhv.bsky.social
Exciting job opportunities here for *TWO* computational researchers to contribute to a new collaborative effort between the @imm.ox.ac.uk and @ludwigcancer.bsky.social focussing on progression to high risk blood cancers and secondary leukaemia. Come join our brilliant team!
We are recruiting! Senior postdoc in computational cancer genomics/epigenomics @ludwigcancer.bsky.social @ox.ac.uk. Lead research into epigenetic drivers of secondary AML with rich omics data + strong clinical/wet-lab collaborations.
cutt.cx/YUoB
We look forward hearing from you!
#epigenetics #jobs
cutt.cx/YUoB
We look forward hearing from you!
#epigenetics #jobs
April 29, 2025 at 6:33 AM
Exciting job opportunities here for *TWO* computational researchers to contribute to a new collaborative effort between the @imm.ox.ac.uk and @ludwigcancer.bsky.social focussing on progression to high risk blood cancers and secondary leukaemia. Come join our brilliant team!
Lovely sunset family picnic serenaded by the geese at the Costa Del Port Meadow. #beautifuloxford
March 28, 2025 at 10:13 PM
Lovely sunset family picnic serenaded by the geese at the Costa Del Port Meadow. #beautifuloxford
We are recruiting!! Ads now live for a Data Coordinator and 2 Research Assistants/biobankers to join a new @ludwigcancer.bsky.social - @imm.ox.ac.uk joint initiative to prevent progression from early- to advanced blood cancer. Joint posts with Adam Mead+others in Oxford Ludwig. Links below
March 27, 2025 at 7:59 AM
We are recruiting!! Ads now live for a Data Coordinator and 2 Research Assistants/biobankers to join a new @ludwigcancer.bsky.social - @imm.ox.ac.uk joint initiative to prevent progression from early- to advanced blood cancer. Joint posts with Adam Mead+others in Oxford Ludwig. Links below
Reposted by Beth Psaila
Thrilled to share new work led by @jieyang437.bsky.social in the lab published today in @Nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. @Cambridge_Uni @CRUKCamCentre rdcu.be/eci1U
March 5, 2025 at 6:56 PM
Thrilled to share new work led by @jieyang437.bsky.social in the lab published today in @Nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. @Cambridge_Uni @CRUKCamCentre rdcu.be/eci1U
Reposted by Beth Psaila
Rare Disease Day is coming up this Friday (28th Feb) 🧪
We spoke with Sarah Gooding, a clinician scientist in @rosschapmanlab.bsky.social's group at the MRC WIMM researching multiple myeloma - a currently incurable type of bone marrow cancer that desperately requires friendlier therapies.
We spoke with Sarah Gooding, a clinician scientist in @rosschapmanlab.bsky.social's group at the MRC WIMM researching multiple myeloma - a currently incurable type of bone marrow cancer that desperately requires friendlier therapies.
Rare Disease Day 2025: Multiple Myeloma
YouTube video by MRC Weatherall Institute of Molecular Medicine
youtu.be
February 24, 2025 at 11:27 AM
Rare Disease Day is coming up this Friday (28th Feb) 🧪
We spoke with Sarah Gooding, a clinician scientist in @rosschapmanlab.bsky.social's group at the MRC WIMM researching multiple myeloma - a currently incurable type of bone marrow cancer that desperately requires friendlier therapies.
We spoke with Sarah Gooding, a clinician scientist in @rosschapmanlab.bsky.social's group at the MRC WIMM researching multiple myeloma - a currently incurable type of bone marrow cancer that desperately requires friendlier therapies.
Check out @imm.ox.ac.uk latest video on innovation - we are fortunate to work in such a dynamic environment, bridging biological discovery and clinical translation @ox.ac.uk @cancerresearchuk.org
At the MRC WIMM, we foster a strong culture of innovation.
In this video, we spoke with some of our current and former Group Leaders who have developed their discoveries into commercial ventures to translate their research into clinics and benefit patients 🧪
Find out more: bit.ly/4b3zL4O
In this video, we spoke with some of our current and former Group Leaders who have developed their discoveries into commercial ventures to translate their research into clinics and benefit patients 🧪
Find out more: bit.ly/4b3zL4O
Innovation at the MRC WIMM
YouTube video by MRC Weatherall Institute of Molecular Medicine
youtu.be
February 18, 2025 at 4:37 PM
Check out @imm.ox.ac.uk latest video on innovation - we are fortunate to work in such a dynamic environment, bridging biological discovery and clinical translation @ox.ac.uk @cancerresearchuk.org
Check out @abattacks.bsky.social’s new and improved bone marrow organoid model - preprint below. More cell types (lymphoid progenitors and osteo- lineage), myeloma modelling and a cool method to improve scalability!
Good morning everyone, I'm pleased to share our latest advance in bone marrow in vitro modelling:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
comBO: A combined human bone and lympho-myeloid bone marrow organoid for pre-clinical modelling of haematopoietic disorders
The bone marrow supports lifelong blood and immune cell production. Current human bone marrow organoid models do not include both lymphoid and myeloid elements and lack the complexity of stromal cell ...
www.biorxiv.org
February 18, 2025 at 4:29 PM
Check out @abattacks.bsky.social’s new and improved bone marrow organoid model - preprint below. More cell types (lymphoid progenitors and osteo- lineage), myeloma modelling and a cool method to improve scalability!
Hugely well deserved @ckbrierley.bsky.social
Congratulations to all the 2024 RDM Graduate Prize Winners, including @ckbrierley.bsky.social & Patrick Pflughaupt, who both completed their PhDs here at the MRC WIMM 🎉
Congratulations to our Graduate Prize Winners! Jamie Kitt, @ckbrierley.bsky.social and Patrick Pflughaupt received this award for exceptional achievement in their research.
Find out about their research - ranging from post partum blood pressure to DNA fragility: www.rdm.ox.ac.uk/news/2024-rd...
Find out about their research - ranging from post partum blood pressure to DNA fragility: www.rdm.ox.ac.uk/news/2024-rd...
February 3, 2025 at 5:00 PM
Hugely well deserved @ckbrierley.bsky.social
Super proud of brilliant NIH-OxCAM PhD student ZoeWong for winning the Doug Higgs Best Abstract award at Oxford Centre for Haematology Day @ox.ac.uk @ouhospitals.bsky.social @imm.ox.ac.uk, for her collab project with @alexrampotas.bsky.social. They are racking up prizes betw them…paper coming!
January 29, 2025 at 7:10 PM
Super proud of brilliant NIH-OxCAM PhD student ZoeWong for winning the Doug Higgs Best Abstract award at Oxford Centre for Haematology Day @ox.ac.uk @ouhospitals.bsky.social @imm.ox.ac.uk, for her collab project with @alexrampotas.bsky.social. They are racking up prizes betw them…paper coming!
Great paper from @immunothrombosis.bsky.social group - platelets alter their functional properties with time since thrombogenesis. Important implications for transfusion storage time!
1/x Online now: Our work on platelet aging and inflammation in @bloodjournal.bsky.social led by superstar PhD student Afra Anjum: ashpublications.org/blood/articl...
January 23, 2025 at 8:08 PM
Great paper from @immunothrombosis.bsky.social group - platelets alter their functional properties with time since thrombogenesis. Important implications for transfusion storage time!
Join Us for the MPN Voice Virtual Forum! 🗓 Date: Monday, 6 January 2025 🕒 Time: 4:30 PM – 6:00 PM (GMT)📍 Location: Online (Zoom). Registration is now open! Focusing on the latest updates from the American Society of Hematology (ASH).
linktr.ee/Mpnvoice
linktr.ee/Mpnvoice
MPN Community: Resources, Support & Donation Options | Linktree
MPN Voice empowers patients with MPNs. Find support groups, resources, and ways to donate to the cause.
linktr.ee
December 23, 2024 at 8:10 AM
Join Us for the MPN Voice Virtual Forum! 🗓 Date: Monday, 6 January 2025 🕒 Time: 4:30 PM – 6:00 PM (GMT)📍 Location: Online (Zoom). Registration is now open! Focusing on the latest updates from the American Society of Hematology (ASH).
linktr.ee/Mpnvoice
linktr.ee/Mpnvoice
So proud of DrLaurenMurphy passing PhD @imm.ox.ac.uk with flying colours.Grateful that she was brave enough to join as 2nd lab recruit 6yrs ago, and determined enough to make a huge success of a high-risk-high-reward PhD inspired by a @cancerresearchuk.org sandpit!Thanks examiners ProfsCurry&Gibbins
December 14, 2024 at 7:04 PM
So proud of DrLaurenMurphy passing PhD @imm.ox.ac.uk with flying colours.Grateful that she was brave enough to join as 2nd lab recruit 6yrs ago, and determined enough to make a huge success of a high-risk-high-reward PhD inspired by a @cancerresearchuk.org sandpit!Thanks examiners ProfsCurry&Gibbins
Excited for this session!
There's no better way to start the new year than by hearing the exciting science of organoids! 🤩 Join us for the first 2025 New Investigator Committee webinar on January 8th.
Kick off the new year with cutting-edge science. Join the NIC, Prof. Christoph Klein and @abattacks.bsky.social for their webinar on "Organoids" happening on Wednesday, 8 January 2025! www.iseh.org/ISEHWebinars
December 13, 2024 at 9:59 PM
Excited for this session!
Reposted by Beth Psaila
Make sure to get your talk submissions in! Can't wait for this conference and the all-star speakers/science!!
🚨 1 week left to secure your Early Bird registration for #MyeloidMalignancies25
🌍 14-17 May 2025, Chania, Crete
🗣️ Talk submissions accepted until 12 Dec
📰 Programme live; remaining slots reserved for abstracts
🖥️ bit.ly/3ZpUESA
🌍 14-17 May 2025, Chania, Crete
🗣️ Talk submissions accepted until 12 Dec
📰 Programme live; remaining slots reserved for abstracts
🖥️ bit.ly/3ZpUESA
December 11, 2024 at 6:58 PM
Make sure to get your talk submissions in! Can't wait for this conference and the all-star speakers/science!!
Terrific talk from the brilliant @antoniorromera.bsky.social this morning on how cells tolerate whole genome duplication and implications for cancer evolution. Check it out on the virtual platform if you missed it!
Very eloquent presentation by Antonio Romera from @bethpsaila.bsky.social lab on megakaryocyte biology and ability to take on DNA damage! Fantastic work #ASH24
December 8, 2024 at 6:52 PM
Terrific talk from the brilliant @antoniorromera.bsky.social this morning on how cells tolerate whole genome duplication and implications for cancer evolution. Check it out on the virtual platform if you missed it!
Very well deserved @alexrampotas.bsky.social ! We are thrilled to work with you and the CAR-T team
Very honoured to receive the ASH-BSH abstract achievement award
The result of the tremendous work by so many talented people who I had the privilege to work with
Zoe Wong, Isaac Gannon, @bethpsaila.bsky.social, Claire Roddie, Martin Pule and many more
#ASH24
The result of the tremendous work by so many talented people who I had the privilege to work with
Zoe Wong, Isaac Gannon, @bethpsaila.bsky.social, Claire Roddie, Martin Pule and many more
#ASH24
December 8, 2024 at 1:24 PM
Very well deserved @alexrampotas.bsky.social ! We are thrilled to work with you and the CAR-T team
Reposted by Beth Psaila
Very pleased to present the results of a UK wide collaborative study on real world efficacy and safety of Momelotininb
- >60% anaemia responses at 6 months
-G1-2 peripheral neuropathy (15%)
-unexpected thrombocytosis (?hepcidin dysregulation due to AVCR1 inhibition)
#ASH24 @bethpsaila.bsky.social
- >60% anaemia responses at 6 months
-G1-2 peripheral neuropathy (15%)
-unexpected thrombocytosis (?hepcidin dysregulation due to AVCR1 inhibition)
#ASH24 @bethpsaila.bsky.social
December 8, 2024 at 6:25 AM
Very pleased to present the results of a UK wide collaborative study on real world efficacy and safety of Momelotininb
- >60% anaemia responses at 6 months
-G1-2 peripheral neuropathy (15%)
-unexpected thrombocytosis (?hepcidin dysregulation due to AVCR1 inhibition)
#ASH24 @bethpsaila.bsky.social
- >60% anaemia responses at 6 months
-G1-2 peripheral neuropathy (15%)
-unexpected thrombocytosis (?hepcidin dysregulation due to AVCR1 inhibition)
#ASH24 @bethpsaila.bsky.social
Sunrise and moonset beyond the Coronado Bridge on a beautiful run around San Diego bay this morning
December 7, 2024 at 4:29 PM
Sunrise and moonset beyond the Coronado Bridge on a beautiful run around San Diego bay this morning
All packed and ready for #ASH24 @ash-hematology.bsky.social! Just trying to decide which essential item to leave behind to get my suitcase to close
December 5, 2024 at 8:56 AM
All packed and ready for #ASH24 @ash-hematology.bsky.social! Just trying to decide which essential item to leave behind to get my suitcase to close
Check out our “In a Nutshell” review in Brit J Haem - When, Which and How to Switch - navigating JAK inhibitors for myelofibrosis onlinelibrary.wiley.com/doi/10.1111/...
When, which and how to switch: Navigating JAK inhibitors in myelofibrosis
Navigating choice of JAK inhibitor (JAKi) therapy for patients with myelofibrosis who are JAKi-naïve and for those who have previously been treated with a JAKi.
onlinelibrary.wiley.com
December 2, 2024 at 10:16 AM
Check out our “In a Nutshell” review in Brit J Haem - When, Which and How to Switch - navigating JAK inhibitors for myelofibrosis onlinelibrary.wiley.com/doi/10.1111/...