Leo Nicolai
@immunothrombosis.bsky.social
Junior Research Group Leader @LMU Munich, interested in vascular biology with a focus on platelets and immunothrombosis
Reposted by Leo Nicolai
#platelets keep surprise me @immunothrombosis.bsky.social as always great imaging
#isth2025 and very interesting par1 signalling in lymphatic endothelial bed SOA7
#isth2025 and very interesting par1 signalling in lymphatic endothelial bed SOA7
June 22, 2025 at 1:27 PM
#platelets keep surprise me @immunothrombosis.bsky.social as always great imaging
#isth2025 and very interesting par1 signalling in lymphatic endothelial bed SOA7
#isth2025 and very interesting par1 signalling in lymphatic endothelial bed SOA7
Online now: Yacine Boulaftali, Steffen Massberg and I summarized recent key insights into the role of platelets in vascular inflammation:
journals.lww.com/co-hematolog...
journals.lww.com/co-hematolog...
May 19, 2025 at 8:38 AM
Online now: Yacine Boulaftali, Steffen Massberg and I summarized recent key insights into the role of platelets in vascular inflammation:
journals.lww.com/co-hematolog...
journals.lww.com/co-hematolog...
Immune cells contribute to thrombosis in mouse models - but what about human disease? We used scRNA Sequencing, flow cytometry and histology to better understand immune cells in human stroke thrombi www.sciencedirect.com/science/arti... now online @cp-immunity.bsky.social
Immunothrombolytic monocyte-neutrophil axes dominate the single-cell landscape of human thrombosis and correlate with thrombus resolution
Thrombotic diseases remain the major cause of death and disability worldwide, and the contribution of inflammation is increasingly recognized. Thrombo…
www.sciencedirect.com
April 24, 2025 at 8:05 PM
Immune cells contribute to thrombosis in mouse models - but what about human disease? We used scRNA Sequencing, flow cytometry and histology to better understand immune cells in human stroke thrombi www.sciencedirect.com/science/arti... now online @cp-immunity.bsky.social
Reposted by Leo Nicolai
#TheMoreTheMerrier! Pekayvaz @immunothrombosis.bsky.social Stark &co show @cp-immunity.bsky.social that non-classical monocytes help to resolve thrombi by recruiting neutrophils that become thrombolytic following hypoxia-induced programs!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Immunothrombolytic monocyte-neutrophil axes dominate the single-cell landscape of human thrombosis and correlate with thrombus resolution
Thrombotic diseases remain the major cause of death and disability worldwide, and the contribution of inflammation is increasingly recognized. Thrombo…
www.sciencedirect.com
April 24, 2025 at 4:04 PM
#TheMoreTheMerrier! Pekayvaz @immunothrombosis.bsky.social Stark &co show @cp-immunity.bsky.social that non-classical monocytes help to resolve thrombi by recruiting neutrophils that become thrombolytic following hypoxia-induced programs!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Very happy to contribute another @bloodjournal.bsky.social cover with our story on aging platelets:
ashpublications.org/blood/articl...
Thoughtful commentary by Laura Gutiérrez in the issue as well.
ashpublications.org/blood/articl...
Thoughtful commentary by Laura Gutiérrez in the issue as well.
Aging platelets shift their hemostatic properties to inflammatory functions
Key PointsPlatelets change their phenotype as they age in circulation, skewing toward inflammatory function over time.Genetic models of increased platelet
ashpublications.org
April 3, 2025 at 8:36 PM
Very happy to contribute another @bloodjournal.bsky.social cover with our story on aging platelets:
ashpublications.org/blood/articl...
Thoughtful commentary by Laura Gutiérrez in the issue as well.
ashpublications.org/blood/articl...
Thoughtful commentary by Laura Gutiérrez in the issue as well.
1/x Online now: Our work on platelet aging and inflammation in @bloodjournal.bsky.social led by superstar PhD student Afra Anjum: ashpublications.org/blood/articl...
January 23, 2025 at 10:39 AM
1/x Online now: Our work on platelet aging and inflammation in @bloodjournal.bsky.social led by superstar PhD student Afra Anjum: ashpublications.org/blood/articl...
Arterial thrombosis - studying platelet recruitment at the single cell level in vivo
November 21, 2024 at 10:05 PM
Arterial thrombosis - studying platelet recruitment at the single cell level in vivo
It was an immense pleasure to host our 2nd #immunothrombosis Symposium @LMU Munich
together with Konstantin Stark. Talks and discussions were outstanding, and new ideas & perspectives made the meeting really special!
together with Konstantin Stark. Talks and discussions were outstanding, and new ideas & perspectives made the meeting really special!
November 21, 2024 at 9:58 PM
It was an immense pleasure to host our 2nd #immunothrombosis Symposium @LMU Munich
together with Konstantin Stark. Talks and discussions were outstanding, and new ideas & perspectives made the meeting really special!
together with Konstantin Stark. Talks and discussions were outstanding, and new ideas & perspectives made the meeting really special!