BacPathLiverpool
@bacpathliv.bsky.social
Bacterial Pathogenesis & Immunity group led by Aras Kadioglu. We work on host-pneumococcal interactions; respiratory carriage, transmission & disease, viral co-infections, mucosal immunity, Tregs, vaccines. We also like Pseudomonas aeruginosa and phages!
Reposted by BacPathLiverpool
Did you know we have a Pre-Clinical Studies Unit? It offers clinically relevant models of infection and disease for testing new vaccine candidates, drugs and therapies. Find out more here: www.thepandemicinstitute.org/collaborate/...
April 10, 2025 at 11:07 AM
Did you know we have a Pre-Clinical Studies Unit? It offers clinically relevant models of infection and disease for testing new vaccine candidates, drugs and therapies. Find out more here: www.thepandemicinstitute.org/collaborate/...
This is so cool.
Tregs…what else can they do?
Tregs…what else can they do?
#Immunology out now @science.org
Regulatory T cells inhibit pain sensing in female, but not male, mice.
buff.ly/SKtHnfK
By Élora Midavaine, Sakeen Kashem et al.
Regulatory T cells inhibit pain sensing in female, but not male, mice.
buff.ly/SKtHnfK
By Élora Midavaine, Sakeen Kashem et al.
April 5, 2025 at 9:43 PM
This is so cool.
Tregs…what else can they do?
Tregs…what else can they do?
Reposted by BacPathLiverpool
Fitness determinants during mice infection for enterotoxigenic Escherichia coli, Salmonella typhimurium, Shigella flexneri and Citrobacter rodentium. #microsky 🦠 www.nature.com/articles/s41...
Inducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice - Nature Microbiology
InducTn-seq, a method for inducible mutagenesis followed by transposon insertion site sequencing, enables temporal control of transposition to bypass population bottlenecks and enable the quantificati...
www.nature.com
April 2, 2025 at 7:34 AM
Fitness determinants during mice infection for enterotoxigenic Escherichia coli, Salmonella typhimurium, Shigella flexneri and Citrobacter rodentium. #microsky 🦠 www.nature.com/articles/s41...
Reposted by BacPathLiverpool
We're pleased to announce a new collaboration with @dstlmod to bring together researchers from both organisations with the aim of strengthening the UK’s ability to detect, understand and combat known and emerging pathogens.
Read more: www.thepandemicinstitute.org/news/new-col...
Read more: www.thepandemicinstitute.org/news/new-col...
March 31, 2025 at 11:57 AM
We're pleased to announce a new collaboration with @dstlmod to bring together researchers from both organisations with the aim of strengthening the UK’s ability to detect, understand and combat known and emerging pathogens.
Read more: www.thepandemicinstitute.org/news/new-col...
Read more: www.thepandemicinstitute.org/news/new-col...
Reposted by BacPathLiverpool
We are a little behind schedule, but the line up for the Next Great Wall Symposium in Sicily in September is coming together more soon. Get ready for those applications for abstracts!!!
thegreatwall-symposium.org
thegreatwall-symposium.org
The Greatwall-symposium
The Great Wall Symposium will take place from 18th to 20th September 2023 at the venue in The Vila Galé Sintra Hotel, in Portugal.
thegreatwall-symposium.org
January 7, 2025 at 3:27 PM
We are a little behind schedule, but the line up for the Next Great Wall Symposium in Sicily in September is coming together more soon. Get ready for those applications for abstracts!!!
thegreatwall-symposium.org
thegreatwall-symposium.org
Interested in doing a PhD on mechanisms of pneumococcal host-to-host transmission? We have a fully funded PhD available now, deadline 26 January. Come and join us!
Deciphering mechanisms of host-to-host transmission in pathogenesis of pneumococcal disease at University of Liverpool on FindAPhD.com
PhD Project - Deciphering mechanisms of host-to-host transmission in pathogenesis of pneumococcal disease at University of Liverpool, listed on FindAPhD.com
www.findaphd.com
January 7, 2025 at 2:42 PM
Interested in doing a PhD on mechanisms of pneumococcal host-to-host transmission? We have a fully funded PhD available now, deadline 26 January. Come and join us!
Nice paper describing the hierarchical structure that controls Pseudomonas aeruginosa virulence; a mutational hotspot that acts as a genetic switch for hypervirulence and AMR.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Mutations in mexT bypass the stringent response dependency of virulence in Pseudomonas aeruginosa
Regulatory systems behind antimicrobial resistance and virulence are poorly understood. Figueroa et al. show that the mutational state of the Pseudomonas aeruginosa regulator mexT acts as a genetic switch, controlling virulence and antibiotic resistance. They further show that mexT mutants are common in clinical isolates and exhibit hypervirulence in vivo.
www.cell.com
December 21, 2024 at 10:13 PM
Nice paper describing the hierarchical structure that controls Pseudomonas aeruginosa virulence; a mutational hotspot that acts as a genetic switch for hypervirulence and AMR.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by BacPathLiverpool
Congratulations to my old supervisors Paul Williams and Miguel Camara on their well deserved retirement. Two excellent mentors who had a great career.
December 11, 2024 at 12:34 AM
Congratulations to my old supervisors Paul Williams and Miguel Camara on their well deserved retirement. Two excellent mentors who had a great career.
Reposted by BacPathLiverpool
Lungs primed by past infections, like enriched soil, resist COVID-19 better, revealing why outcomes vary.
@mayerbarber.bsky.social @pauljbaker.bsky.social @kerryhilligan.bsky.social @danbarberphd.bsky.social @niaidnews.bsky.social @sciimmunology.bsky.social
t.co/5L7vmTbsNN
#ImmunoSky 🧪
@mayerbarber.bsky.social @pauljbaker.bsky.social @kerryhilligan.bsky.social @danbarberphd.bsky.social @niaidnews.bsky.social @sciimmunology.bsky.social
t.co/5L7vmTbsNN
#ImmunoSky 🧪
December 12, 2024 at 11:16 AM
Lungs primed by past infections, like enriched soil, resist COVID-19 better, revealing why outcomes vary.
@mayerbarber.bsky.social @pauljbaker.bsky.social @kerryhilligan.bsky.social @danbarberphd.bsky.social @niaidnews.bsky.social @sciimmunology.bsky.social
t.co/5L7vmTbsNN
#ImmunoSky 🧪
@mayerbarber.bsky.social @pauljbaker.bsky.social @kerryhilligan.bsky.social @danbarberphd.bsky.social @niaidnews.bsky.social @sciimmunology.bsky.social
t.co/5L7vmTbsNN
#ImmunoSky 🧪
This is more like it;
“You can send your manuscript here without suffering waves of anxiety regarding the eventual fate of your submission. You know with 100% certainty that it will not be accepted. You are also free to resubmit to other journals even before our review process is complete”
“You can send your manuscript here without suffering waves of anxiety regarding the eventual fate of your submission. You know with 100% certainty that it will not be accepted. You are also free to resubmit to other journals even before our review process is complete”
Journal of Universal Rejection
www.universalrejection.org
November 26, 2024 at 8:28 PM
This is more like it;
“You can send your manuscript here without suffering waves of anxiety regarding the eventual fate of your submission. You know with 100% certainty that it will not be accepted. You are also free to resubmit to other journals even before our review process is complete”
“You can send your manuscript here without suffering waves of anxiety regarding the eventual fate of your submission. You know with 100% certainty that it will not be accepted. You are also free to resubmit to other journals even before our review process is complete”
Interested in phage therapy, host immunity and infection models? Join our group for fully funded PhD available now - deadline 25 November.
Delivery Strategies in Phage Therapy: Balancing Host Responses and Therapeutic Efficacy at University of Liverpool on FindAPhD.com
PhD Project - Delivery Strategies in Phage Therapy: Balancing Host Responses and Therapeutic Efficacy at University of Liverpool, listed on FindAPhD.com
www.findaphd.com
November 18, 2024 at 1:34 AM
Interested in phage therapy, host immunity and infection models? Join our group for fully funded PhD available now - deadline 25 November.
Reposted by BacPathLiverpool
The UKHSA ESPAUR report is out today. It's a massive report on the use of antimicrobials in England and the epidemiology of antimicrobial resistance.
Bonus data: also includes preliminary results of the #hcai point prevalence survey.
www.gov.uk/government/p...
Bonus data: also includes preliminary results of the #hcai point prevalence survey.
www.gov.uk/government/p...
English surveillance programme for antimicrobial utilisation and resistance (ESPAUR) report
The ESPAUR report includes national data on antimicrobial prescribing and resistance, antimicrobial stewardship implementation, and awareness activities.
www.gov.uk
November 14, 2024 at 6:20 PM
The UKHSA ESPAUR report is out today. It's a massive report on the use of antimicrobials in England and the epidemiology of antimicrobial resistance.
Bonus data: also includes preliminary results of the #hcai point prevalence survey.
www.gov.uk/government/p...
Bonus data: also includes preliminary results of the #hcai point prevalence survey.
www.gov.uk/government/p...
Reposted by BacPathLiverpool
NIAID releases alternative to BioRender, all illustrations freely available in public domain
bioart.niaid.nih.gov
bioart.niaid.nih.gov
October 30, 2024 at 2:46 PM
NIAID releases alternative to BioRender, all illustrations freely available in public domain
bioart.niaid.nih.gov
bioart.niaid.nih.gov
Reposted by BacPathLiverpool
Call for papers on Evolution of Immunity!
Please get in touch if you have something in this area that you might like to submit to a collection at BMC Biology.
Details: biomedcentral.com/collections/...
#Evolution #Immunity #Immunology
Please get in touch if you have something in this area that you might like to submit to a collection at BMC Biology.
Details: biomedcentral.com/collections/...
#Evolution #Immunity #Immunology
Call for papers - Evolution of immunity
biomedcentral.com
November 14, 2024 at 2:49 PM
Call for papers on Evolution of Immunity!
Please get in touch if you have something in this area that you might like to submit to a collection at BMC Biology.
Details: biomedcentral.com/collections/...
#Evolution #Immunity #Immunology
Please get in touch if you have something in this area that you might like to submit to a collection at BMC Biology.
Details: biomedcentral.com/collections/...
#Evolution #Immunity #Immunology
Reposted by BacPathLiverpool
We're the American Thoracic Society, thinking about this platform. Hmm.. Any members here? Learn more at thoracic.org
American Thoracic Society | Home
The American Thoracic Society is the world's leading medical society dedicated to accelerating the advancement of global respiratory health through…
thoracic.org
November 11, 2024 at 11:37 PM
We're the American Thoracic Society, thinking about this platform. Hmm.. Any members here? Learn more at thoracic.org
GBS LytSR plays a key role in tissue invasion and persistence of mucosal colonisation.
The Streptococcus agalactiae LytSR two-component regulatory system promotes vaginal colonization and virulence in vivo | Microbiology Spectrum
Streptococcus agalactiae (group B Streptococcus, or GBS) is a common commensal of the female urogenital tract and one of WHO’s priority
pathogens. The bacterium has evolved mechanisms to adapt and sur...
journals.asm.org
November 14, 2024 at 12:10 AM
GBS LytSR plays a key role in tissue invasion and persistence of mucosal colonisation.
Reposted by BacPathLiverpool
Straight from the cellars of NIPH, we have a paper out on pneumococcal lineage (GPSC) dynamics in response to childhood vaccination. Resuscitating freeze-dried cultures was a substantial effort, but worked surprisingly well. Have a look if interested! genomemedicine.biomedcentral.com/articles/10....
A genome-based survey of invasive pneumococci in Norway over four decades reveals lineage-specific responses to vaccination - Genome Medicine
Background Streptococcus pneumoniae is a major cause of mortality globally. The introduction of pneumococcal conjugate vaccines (PCVs) has reduced the incidence of the targeted serotypes significantly...
genomemedicine.biomedcentral.com
October 26, 2024 at 3:14 PM
Straight from the cellars of NIPH, we have a paper out on pneumococcal lineage (GPSC) dynamics in response to childhood vaccination. Resuscitating freeze-dried cultures was a substantial effort, but worked surprisingly well. Have a look if interested! genomemedicine.biomedcentral.com/articles/10....
Reposted by BacPathLiverpool
Have you submitted your abstract for our one-day programme on antimicrobial resistance as part of @Co_Biologists #biologists100 conference in Liverpool, UK in March 2025? Find out more, register and submit an abstract at tinyurl.com/4jurepus
October 20, 2024 at 5:47 PM
Have you submitted your abstract for our one-day programme on antimicrobial resistance as part of @Co_Biologists #biologists100 conference in Liverpool, UK in March 2025? Find out more, register and submit an abstract at tinyurl.com/4jurepus
Reposted by BacPathLiverpool
Next year's Microbiology Society Annual Conference 2025 will be held here in the bracing and beautiful port city of Liverpool 31st March – 3rd April!
Watch out: abstract submission deadline is earlier than previous years, on the 12th November...
microbiologysociety.org/event/annual...
Watch out: abstract submission deadline is earlier than previous years, on the 12th November...
microbiologysociety.org/event/annual...
Annual Conference 2025
microbiologysociety.org
October 31, 2024 at 10:22 AM
Next year's Microbiology Society Annual Conference 2025 will be held here in the bracing and beautiful port city of Liverpool 31st March – 3rd April!
Watch out: abstract submission deadline is earlier than previous years, on the 12th November...
microbiologysociety.org/event/annual...
Watch out: abstract submission deadline is earlier than previous years, on the 12th November...
microbiologysociety.org/event/annual...
Reposted by BacPathLiverpool
Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics.
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
November 13, 2024 at 12:46 PM
Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics.
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell
www.sciencedirect.com/science/arti...
Reposted by BacPathLiverpool
A little crucial reminder that vaccines save lives. Analysis by WHO shows that global immunisation to 14 diseases (polio, measles, meningitis) has saved approximately 154million lives- 101million of those were infants. 🧪🧵
Global immunization efforts have saved at least 154 million lives over the past 50 years
A major landmark study reveals that global immunization efforts have saved an estimated 154 million lives – or the equivalent of 6 lives every minute of every year – over the past 50 years. The vast m...
www.who.int
November 12, 2024 at 3:48 PM
A little crucial reminder that vaccines save lives. Analysis by WHO shows that global immunisation to 14 diseases (polio, measles, meningitis) has saved approximately 154million lives- 101million of those were infants. 🧪🧵
Join our group for exciting new PhD project on “Ageing-related susceptibility to pneumococcal pneumonia”
MRC DiMeN Doctoral Training Partnership. Deadline 13 Dec.
MRC DiMeN Doctoral Training Partnership. Deadline 13 Dec.
MRC DiMeN Doctoral Training Partnership: Ageing-related susceptibility to pneumococcal pneumonia at University of Liverpool on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Ageing-related susceptibility to pneumococcal pneumonia at University of Liverpool, listed on FindAPhD.com
www.findaphd.com
November 13, 2024 at 6:35 PM
Join our group for exciting new PhD project on “Ageing-related susceptibility to pneumococcal pneumonia”
MRC DiMeN Doctoral Training Partnership. Deadline 13 Dec.
MRC DiMeN Doctoral Training Partnership. Deadline 13 Dec.
Fellowship candidates! Want to join us and work on pneumococcus, GAS, GBS or Pseudomonas aeruginosa? Interested in host pathogen interactions, infection immunology and vaccine research? Get in touch! We can discuss projects and sponsorship of your fellowship proposal.
November 13, 2024 at 6:33 PM
Fellowship candidates! Want to join us and work on pneumococcus, GAS, GBS or Pseudomonas aeruginosa? Interested in host pathogen interactions, infection immunology and vaccine research? Get in touch! We can discuss projects and sponsorship of your fellowship proposal.