Aurélien Courtois
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aureliencourtois.bsky.social
Aurélien Courtois
@aureliencourtois.bsky.social
Scientist / Researcher @The Crick

Interest: Developmental biology, epigenetic and evolution, in the opossum and other mammals.

Current position: postdoc in Turner lab.
https://www.crick.ac.uk/research/labs/james-turner

(He/him)
Pinned
Interests: Embryo development, evo-devo, mammals, science communication, epigenetic.

Skills: live-imaging, micromanipulation.

Current research: blastocyst formation, X silencing in opossum.

My science illustrations are from @akira-sciart.bsky.social
Reposted by Aurélien Courtois
❓Can a father’s environmental exposures before conception influence their offspring?

We systematically tackled this - identifying effects of paternal age, environment and genetics on early embryos - as well as confounding influences

www.embopress.org/doi/full/10....
Embryonic signatures of intergenerational epigenetic inheritance across paternal environments and genetic backgrounds | The EMBO Journal
imageimagePaternal environmental exposures have been linked with modulation of phenotype and disease risk in offspring via largely unclear mechanisms. This study employs in vitro fertilization and sin...
www.embopress.org
September 27, 2025 at 7:28 AM
Reposted by Aurélien Courtois
✨Nervous about development? Don’t be! 🧠 E13.5 🐁 embryo showing nerves (🩵) and endothelial cells (💙) weaving together in the developing pup 🔬 image by Nathan Burns 🧪 #FluorescenceFriday #DevBio #MouseEmbryo
September 5, 2025 at 9:20 PM
Reposted by Aurélien Courtois
Today, Edith Heard begins her tenure as our new Chief Executive Officer. Edith joins us from @embl.org, and will head up the new Developmental Epigenetics Laboratory alongside her executive role.

www.crick.ac.uk/news/2025-09...
Welcome Edith Heard
Today, Edith Heard begins her tenure as Chief Executive Officer of the Francis Crick Institute
www.crick.ac.uk
September 1, 2025 at 12:09 PM
Reposted by Aurélien Courtois
Thrilled to share that our latest work on marsupial heterochrony is now online at @cp-devcell.bsky.social @cellpress.bsky.social @lab-turner.bsky.social @crick.ac.uk We used scRNAseq to understand the asynchronous progression of developmental programmes in marsupials www.cell.com/developmenta...
Marsupial single-cell transcriptomics identifies temporal diversity in mammalian developmental programs
Menchero et al. generate a single-cell transcriptomic atlas in the opossum and show rapid progression of transcriptional programs in specific tissues relative to morphological landmarks. This shift in...
www.cell.com
July 24, 2025 at 5:07 PM
In Paris for a nice ''colloque'' on X chromosome inactivation. Looking forward to it!
www.college-de-france.fr/fr/agenda/co...
June 9, 2025 at 8:07 PM
Reposted by Aurélien Courtois
Who doesn't like looking at stunning images showcasing the beauty of #DevBio?? 😍
May 15, 2025 at 8:15 AM
Reposted by Aurélien Courtois
We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵
Divergent DNA methylation dynamics in marsupial and eutherian embryos - Nature
A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.
www.nature.com
May 14, 2025 at 4:01 PM
New paper from our lab !
DNA methylation dynamic is different in marsupial embryos compared to eutherian embryos.
May 14, 2025 at 4:00 PM
Light-sheet is amazing ! Nice work from Kenzo and his lab. !!
May 14, 2025 at 12:04 PM
Enjoyed a lot the Developmental Biology GRC 2025 last month.
Thank you @swathiarur.bsky.social, Kathy Cheah and Anna Kircheva for organising it!
Looking forward to the 2027 edition !
May 7, 2025 at 3:00 PM
The Crick is part of the organisation of a bioimage analysis conference in Kobe, Japan, 26-31 October 2025.
It includes training school, hackathon, taggathon and symposium, and there is travel support for training school attendees:
www.globias.org/activities/b...
Bioimage Analysis Conference 2025 in Kobe
GloBIAS Bioimage Analysis Conference 2025 Oct 26, 2025 - Oct 31, 2025 | Kobe, Japan Venue: RIKEN BDR, Kobe, Japan Registration via Google Forms here: https://tinyurl.com/3dtajhh6 Please follow the l...
www.globias.org
May 7, 2025 at 2:52 PM
Reposted by Aurélien Courtois
A woman studies embryos for decades, struggles for funding and respect. She publishes under her husband’s name, until they divorce. A single mother, she moves across an ocean to continue her studies. It all sounds quite modern, until you learn that she also worried she’d be burned as a witch. 🧵 1/15
March 11, 2025 at 4:04 PM
Unfortunately, James cannot make it to the Developmental Biology GRC. So, I will give his talk instead. See you in California. #GordonConf
March 6, 2025 at 12:40 PM
If you think we all should have cool science themed Tshirts, go follow him on instagram and ask him to design your ideas !
New posts on instagram!
Follow me there if you want to see more about my clothes design.

#sciart #scienceillustrator #clothesdesign #graphicartist
March 4, 2025 at 7:27 PM
Forgot to post.
Come talk to me about why opossum are such an amazing developmental model. #Beddingtonconf
February 10, 2025 at 8:14 PM
Very excited by the line up at the Beddington symposium this year.
lot of great speakers (@maitrejl.bsky.social depicted)
February 10, 2025 at 11:23 AM
Congrats Jérémie, good luck on your exciting post-doc !
We thrilled to see our latest study led by @jeremie-subrini.bsky.social now out in @science.org 🔬

What are the specific functions of each Y-chromosome gene in fertility ? We generated and studied 13 Y-gene KO mouse models to find out! 🧬

www.science.org/doi/full/10....
www.science.org
January 24, 2025 at 3:03 PM
Thanks preLights for highlighting our preprint !
📢WHO – The X and Y. WHEN – Since the beginning. HOW - From a distance

Mansi highlights a #preprint from Daniel Snell, James Turner and team @crick.ac.uk on the early impact of sex chromosomes in preimplantation mouse embryos.
👀⤵️
prelights.biologists.com/highlights/s...
Sex chromosomes shape the transcriptional landscape of the preimplantation mouse embryo - preLights
WHO – The X and Y. WHEN – Since the beginning. HOW - From a distance
prelights.biologists.com
January 17, 2025 at 4:32 PM
Looking for labs working on afrotheria embryo development.

Does anybody work on elephant shrews, hyraxes, tenrecs ... ?
December 11, 2024 at 11:31 AM
@mpi-ie.bsky.social
7th epigenetics meeting has started. Come talk to me if you're around poster #12. Topics: Opossum, mouse, X inactivation, sex chromosomes, development...
December 4, 2024 at 2:35 PM
Our (Turner lab.) latest preprint is out! 🐭🧬We show that sex chromosomes regulate the transcriptional and developmental landscape of the mouse preimplantation embryo.
www.biorxiv.org/content/10.1...
November 28, 2024 at 3:23 PM
Interests: Embryo development, evo-devo, mammals, science communication, epigenetic.

Skills: live-imaging, micromanipulation.

Current research: blastocyst formation, X silencing in opossum.

My science illustrations are from @akira-sciart.bsky.social
November 27, 2024 at 5:52 PM