Ashley Peer
@ashophagy.bsky.social
5th year immunology phd candidate @ UNMC
microbiologist | MSU alum
innate immunity, immunometabolism, ahr signaling, gut microbiome, alcohol use disorder
self-proclaimed coffee connoisseur, comprised of carbon and bad timing 🏳️🌈 | 🐈⬛☕️🎮
all views are my own
microbiologist | MSU alum
innate immunity, immunometabolism, ahr signaling, gut microbiome, alcohol use disorder
self-proclaimed coffee connoisseur, comprised of carbon and bad timing 🏳️🌈 | 🐈⬛☕️🎮
all views are my own
Reposted by Ashley Peer
Fewer grad students means less science, but many STEM PhD programs in the US are cutting back on admissions this year due to federal funding uncertainties. Words by me for @nature.com:
www.nature.com/articles/d41...
@emsque.bsky.social @ucsdcooperlab.bsky.social @julieposselt.bsky.social 🧪
www.nature.com/articles/d41...
@emsque.bsky.social @ucsdcooperlab.bsky.social @julieposselt.bsky.social 🧪
US PhD admissions shrink as fears over Trump’s cuts take hold
Some doctoral programmes are admitting no students at all amid uncertainty about federal science funding.
www.nature.com
October 21, 2025 at 8:47 PM
Fewer grad students means less science, but many STEM PhD programs in the US are cutting back on admissions this year due to federal funding uncertainties. Words by me for @nature.com:
www.nature.com/articles/d41...
@emsque.bsky.social @ucsdcooperlab.bsky.social @julieposselt.bsky.social 🧪
www.nature.com/articles/d41...
@emsque.bsky.social @ucsdcooperlab.bsky.social @julieposselt.bsky.social 🧪
Reposted by Ashley Peer
Dear #microbiology and #immunology community- I took a break from social media after I deleted my Twitter account, but am back here. Please help me rebuild my community by following me and amplifying this message- I will follow you back. Thank you and I look forward to our many interactions!
October 5, 2025 at 4:10 PM
Dear #microbiology and #immunology community- I took a break from social media after I deleted my Twitter account, but am back here. Please help me rebuild my community by following me and amplifying this message- I will follow you back. Thank you and I look forward to our many interactions!
Monocyte-specific aryl hydrocarbon receptor deficiency leads to microbiota-mediated tonic cytokine response via STING pathway 🧪 www.jci.org/articles/vie...
JCI -
Aryl hydrocarbon receptor restrains tonic cytokine responses by inhibiting microbiota sensing in monocytes
www.jci.org
October 6, 2025 at 6:05 PM
Monocyte-specific aryl hydrocarbon receptor deficiency leads to microbiota-mediated tonic cytokine response via STING pathway 🧪 www.jci.org/articles/vie...
Reposted by Ashley Peer
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 5, 2025 at 12:03 PM
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Reposted by Ashley Peer
Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass...
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
October 2, 2025 at 5:11 PM
Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass...
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
Reposted by Ashley Peer
Interested in metabolism? So are we! My lab has been exploring the cell biology of energy metabolism in the nervous system, and we are looking for postdocs. Cool sensors and microscopy, great work environment. Please help me spread the word!
October 2, 2025 at 12:15 AM
Interested in metabolism? So are we! My lab has been exploring the cell biology of energy metabolism in the nervous system, and we are looking for postdocs. Cool sensors and microscopy, great work environment. Please help me spread the word!
Reposted by Ashley Peer
Working on immunometabolism? Or looking for people who do? Then here’s the starter pack for you! 😊 #Immunosky
go.bsky.app/MvxkA4Q
go.bsky.app/MvxkA4Q
November 24, 2024 at 1:35 PM
Working on immunometabolism? Or looking for people who do? Then here’s the starter pack for you! 😊 #Immunosky
go.bsky.app/MvxkA4Q
go.bsky.app/MvxkA4Q
Reposted by Ashley Peer
A history of alcohol use disorder increases the risk of death from sepsis. Researchers found that the HIF-1α-PFKP axis regulates glycolysis and phagocytosis in ethanol-exposed macrophages and is a potential therapeutic target in ethanol with sepsis: ow.ly/S5AQ50WOgnB.
Mitoquinol improves phagocytosis and glycolysis in ethanol-exposed macrophages via HIF-1α-PFKP axis
Abstract. Alcohol use disorder increases sepsis mortality. Acute ethanol exposure impairs pathogen clearance in the macrophages via dampened glycolysis and
ow.ly
September 3, 2025 at 4:35 PM
A history of alcohol use disorder increases the risk of death from sepsis. Researchers found that the HIF-1α-PFKP axis regulates glycolysis and phagocytosis in ethanol-exposed macrophages and is a potential therapeutic target in ethanol with sepsis: ow.ly/S5AQ50WOgnB.
Reposted by Ashley Peer
Respiratory viral infections awaken metastatic breast cancer cells in lungs
Note: This concerns many infections (inflammation, trauma), including respiratory viruses and is NOT specific for SARS-CoV-2 as some claim.
www.nature.com/artic...
1/9
Note: This concerns many infections (inflammation, trauma), including respiratory viruses and is NOT specific for SARS-CoV-2 as some claim.
www.nature.com/artic...
1/9
Respiratory viral infections awaken metastatic breast cancer cells in lungs
Nature - Mouse models show that respiratory infections from viruses such as influenza and SARS-CoV-2 can trigger metastasis of dormant breast cancer cells in the lungs, a finding supported by...
www.nature.com
July 31, 2025 at 9:33 AM
Respiratory viral infections awaken metastatic breast cancer cells in lungs
Note: This concerns many infections (inflammation, trauma), including respiratory viruses and is NOT specific for SARS-CoV-2 as some claim.
www.nature.com/artic...
1/9
Note: This concerns many infections (inflammation, trauma), including respiratory viruses and is NOT specific for SARS-CoV-2 as some claim.
www.nature.com/artic...
1/9
Reposted by Ashley Peer
ICYMI:
Species-specific serine metabolism differentially controls natural killer cell functions
Nature Metabolism, Published online: 14 August 2025; doi:10.1038/s42255-025-01348-0Li et al. characterize overlapping and divergent metabolic requirements of human and murine NK cells in response to activation, with a focus on serine metabolism
bit.ly
August 22, 2025 at 6:07 AM
ICYMI:
@unmc.bsky.social SUARP program ended yesterday, and our undergraduate student who was such a pleasure to have with us this summer presented a wonderful poster on how alcohol affects the metabolic capacity of the gut microbiome! See more about his experience here: www.linkedin.com/posts/benjam... 🧪
Five months ago, I shared that I'd be working with Dr. | Benjamin Hoover
Five months ago, I shared that I'd be working with Dr. Derrick Samuelson at the University of Nebraska Medical Center in the Internal Medicine Department as a part of the Summer Undergraduate Research...
www.linkedin.com
August 8, 2025 at 6:34 PM
@unmc.bsky.social SUARP program ended yesterday, and our undergraduate student who was such a pleasure to have with us this summer presented a wonderful poster on how alcohol affects the metabolic capacity of the gut microbiome! See more about his experience here: www.linkedin.com/posts/benjam... 🧪
Just submitted my application and working model for my NIH F31 for #BioRenderForGrants! This model has implications not only in alcohol research, but also in various other fields. If we can force cells to “reroute” to a different metabolic pathway, we may be able to restore effector function.
August 1, 2025 at 4:15 PM
Just submitted my application and working model for my NIH F31 for #BioRenderForGrants! This model has implications not only in alcohol research, but also in various other fields. If we can force cells to “reroute” to a different metabolic pathway, we may be able to restore effector function.
Reposted by Ashley Peer
A US Senate committee endorsed maintaining the NIH's structure and increasing its funding by US$400 million, or about 1%
go.nature.com/4mg193S
go.nature.com/4mg193S
‘Congress has your back’: US senators tell scientists they want to protect NIH budget
Senate budget bill includes small increase for the health-research agency — but faces a long road before being signed into law.
go.nature.com
August 1, 2025 at 1:14 PM
A US Senate committee endorsed maintaining the NIH's structure and increasing its funding by US$400 million, or about 1%
go.nature.com/4mg193S
go.nature.com/4mg193S
Reposted by Ashley Peer
If you've ever *benefitted* from NIH research (big population), CALL YOUR SENATOR now to let them know.
⏰ Tmrw morning, Senate appropriators will mark up NIH's FY26 budget.
Personal examples help.
My own case: decades of *sustained* investment in NIH-funded cancer research saved my life.
⏰ Tmrw morning, Senate appropriators will mark up NIH's FY26 budget.
Personal examples help.
My own case: decades of *sustained* investment in NIH-funded cancer research saved my life.
1/11 Though it's personal, I’m sharing this analogy if it helps others: In the last few weeks, I’ve been thinking a lot about my past journey with cancer.
Years ago, I found out in the worst way. My doctor accidentally released the biopsy results to my online patient portal.
🧵 Thread
Years ago, I found out in the worst way. My doctor accidentally released the biopsy results to my online patient portal.
🧵 Thread
July 30, 2025 at 2:37 PM
If you've ever *benefitted* from NIH research (big population), CALL YOUR SENATOR now to let them know.
⏰ Tmrw morning, Senate appropriators will mark up NIH's FY26 budget.
Personal examples help.
My own case: decades of *sustained* investment in NIH-funded cancer research saved my life.
⏰ Tmrw morning, Senate appropriators will mark up NIH's FY26 budget.
Personal examples help.
My own case: decades of *sustained* investment in NIH-funded cancer research saved my life.
Reposted by Ashley Peer
HOW COOL IS THIS? Researchers have developed a DENTAL FLOSS that can DELIVER vaccines THROUGH the gums, a method that could one day offer a NEEDLE-FREE alternative for vaccination. This approach effectively stimulated immunity AND provided FULL protection against a lethal strain of influenza. 🧪🧵⬇️
July 25, 2025 at 4:00 PM
HOW COOL IS THIS? Researchers have developed a DENTAL FLOSS that can DELIVER vaccines THROUGH the gums, a method that could one day offer a NEEDLE-FREE alternative for vaccination. This approach effectively stimulated immunity AND provided FULL protection against a lethal strain of influenza. 🧪🧵⬇️
My first review paper got its first citation today! To celebrate, I’m putting it back on everyone’s feed: an overview of the microbiome in allergy, asthma, and occupational lung disease: link.springer.com/article/10.1... #ImmunoSky #MicrobiomeSky #AllergySky 🧪
The Role of the Microbiome in Allergy, Asthma, and Occupational Lung Disease - Current Allergy and Asthma Reports
Purpose of Review The human commensal microbiota is now widely accepted as a key regulator of human health and disease. The composition of the mucosal associated microbiota has been shown to play a cr...
link.springer.com
July 25, 2025 at 9:02 PM
My first review paper got its first citation today! To celebrate, I’m putting it back on everyone’s feed: an overview of the microbiome in allergy, asthma, and occupational lung disease: link.springer.com/article/10.1... #ImmunoSky #MicrobiomeSky #AllergySky 🧪
Reposted by Ashley Peer
🚨🚨🚨PUI TT Job Alert!!
My dept at TCNJ is hiring a tenure track cell and molecular biologist. Come join my supportive colleagues, helpful staff, & fabulous students!
We're surprisingly well resourced w/excellent equipment (confocal, SEM etc) and research w/students counts towards our teaching load!
My dept at TCNJ is hiring a tenure track cell and molecular biologist. Come join my supportive colleagues, helpful staff, & fabulous students!
We're surprisingly well resourced w/excellent equipment (confocal, SEM etc) and research w/students counts towards our teaching load!
Assistant Professor - Biology
Click the link provided to see the complete job description.
tcnj.taleo.net
July 17, 2025 at 9:45 PM
🚨🚨🚨PUI TT Job Alert!!
My dept at TCNJ is hiring a tenure track cell and molecular biologist. Come join my supportive colleagues, helpful staff, & fabulous students!
We're surprisingly well resourced w/excellent equipment (confocal, SEM etc) and research w/students counts towards our teaching load!
My dept at TCNJ is hiring a tenure track cell and molecular biologist. Come join my supportive colleagues, helpful staff, & fabulous students!
We're surprisingly well resourced w/excellent equipment (confocal, SEM etc) and research w/students counts towards our teaching load!
Reposted by Ashley Peer
My university has announced a special international graduate fellowship for PhD students whose acceptance at a US university has been rescinded. Check it out: grad.uwo.ca/finances/wes...
US-CAN Doctoral Excellence Award
Western University, in vibrant London, Ontario, delivers an academic and student experience second to none.
grad.uwo.ca
July 8, 2025 at 3:14 PM
My university has announced a special international graduate fellowship for PhD students whose acceptance at a US university has been rescinded. Check it out: grad.uwo.ca/finances/wes...
Reposted by Ashley Peer
As the US breaks a 3-decade milestone for measles cases in one year, I'm reflecting on my worst timed paper ever.
I still stand by the points made here. The world, but one leader, remains ready for the endgame. The resonance of the abdication of US leadership is deafening.
I still stand by the points made here. The world, but one leader, remains ready for the endgame. The resonance of the abdication of US leadership is deafening.
Rubella and measles: The beginning of the endgame
Benchmarks must be established and progress tracked to set a global target and take action
www.science.org
July 7, 2025 at 2:07 PM
As the US breaks a 3-decade milestone for measles cases in one year, I'm reflecting on my worst timed paper ever.
I still stand by the points made here. The world, but one leader, remains ready for the endgame. The resonance of the abdication of US leadership is deafening.
I still stand by the points made here. The world, but one leader, remains ready for the endgame. The resonance of the abdication of US leadership is deafening.
Reposted by Ashley Peer
We’re doing a July 4 feature all week highlighting how funding science is patriotic (and the incredible researchers doing life changing, tax payer funded research!) Give us a follow!
Happy July 4th! Here at Your Neighborhood Scientist, we’re excited to highlight American patriotism in a way you might not always think about: scientific research.
neighborhoodscientist.org/posts/2025/j...
neighborhoodscientist.org/posts/2025/j...
July 4, 2025 at 4:01 PM
We’re doing a July 4 feature all week highlighting how funding science is patriotic (and the incredible researchers doing life changing, tax payer funded research!) Give us a follow!
Reposted by Ashley Peer
Microbial Tryptophan Metabolism Activates Host Lysosomal Activity to Facilitate Lipid Breakdown and Ameliorate Hepatic Steatosis https://www.biorxiv.org/content/10.1101/2025.06.28.662086v1
July 3, 2025 at 10:32 AM
Microbial Tryptophan Metabolism Activates Host Lysosomal Activity to Facilitate Lipid Breakdown and Ameliorate Hepatic Steatosis https://www.biorxiv.org/content/10.1101/2025.06.28.662086v1
Reposted by Ashley Peer
Multiomics Approach to Regionally Profile Zinc-Driven Host-Gut Microbiome Interactions in the Intestinal Tract https://www.biorxiv.org/content/10.1101/2025.07.02.662895v1
July 3, 2025 at 3:02 PM
Multiomics Approach to Regionally Profile Zinc-Driven Host-Gut Microbiome Interactions in the Intestinal Tract https://www.biorxiv.org/content/10.1101/2025.07.02.662895v1
Human gut bacteria bioaccumulate PFAS in dense cluster aggregates; PFAS levels in gnotobiotic mouse GI tract & feces is microbiota-dependent
Via @natmicrobiol.nature.com 🧪
www.nature.com/articles/s41...
Via @natmicrobiol.nature.com 🧪
www.nature.com/articles/s41...
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances - Nature Microbiology
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances (PFAS), commonly known as forever chemicals, in intracellular aggregates. Colonization of gnotobiotic mice with bioaccumulating bac...
www.nature.com
July 3, 2025 at 1:47 AM
Human gut bacteria bioaccumulate PFAS in dense cluster aggregates; PFAS levels in gnotobiotic mouse GI tract & feces is microbiota-dependent
Via @natmicrobiol.nature.com 🧪
www.nature.com/articles/s41...
Via @natmicrobiol.nature.com 🧪
www.nature.com/articles/s41...
Reposted by Ashley Peer
Preprint: PD-L1 ligation on NK cells induces a metabolic shift from glycolysis to fatty acid oxidation, enhancing tumor infiltration and control
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
July 3, 2025 at 1:38 AM
Preprint: PD-L1 ligation on NK cells induces a metabolic shift from glycolysis to fatty acid oxidation, enhancing tumor infiltration and control
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Ashley Peer
To all US citizens: now is the moment to call both your Senators and your Congressional Rep, tell them to vote NO to this atrocity and let them know you are following their every move and it doesn’t matter if they are D or R just blow up their phones. GO.
www.congress.gov/members/map?...
www.congress.gov/members/map?...
July 1, 2025 at 1:45 PM
To all US citizens: now is the moment to call both your Senators and your Congressional Rep, tell them to vote NO to this atrocity and let them know you are following their every move and it doesn’t matter if they are D or R just blow up their phones. GO.
www.congress.gov/members/map?...
www.congress.gov/members/map?...