Arthur Frouin
@artfr.bsky.social
Postdoc in Statistical Genetic Unit at Institut Pasteur.
Bacteria enthousiast.
Proud dad.
Bacteria enthousiast.
Proud dad.
Reposted by Arthur Frouin
Ca n'est pas si souvent, un article publié dans Nature met ma communauté à l'honneur (la bioinformatique des séquences). Je vous raconte ?
www.nature.com/articles/d41...
www.nature.com/articles/d41...
‘Google for DNA’ brings order to biology’s big data
MetaGraph compresses vast data archives into a search engine for scientists, opening up new frontiers of biological discovery.
www.nature.com
October 9, 2025 at 3:00 PM
Ca n'est pas si souvent, un article publié dans Nature met ma communauté à l'honneur (la bioinformatique des séquences). Je vous raconte ?
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Arthur Frouin
And it's posted! If you're interested and eligible, please consider applying through the UMD portal: umd.wd1.myworkdayjobs.com/en-US/UMCP/j....
If you're a PI working in algorithmic genomics (& you can recommend my lab to your top graduating students ;P), please let them know!
If you're a PI working in algorithmic genomics (& you can recommend my lab to your top graduating students ;P), please let them know!
October 8, 2025 at 4:53 PM
And it's posted! If you're interested and eligible, please consider applying through the UMD portal: umd.wd1.myworkdayjobs.com/en-US/UMCP/j....
If you're a PI working in algorithmic genomics (& you can recommend my lab to your top graduating students ;P), please let them know!
If you're a PI working in algorithmic genomics (& you can recommend my lab to your top graduating students ;P), please let them know!
Reposted by Arthur Frouin
September 10, 2025 at 4:27 PM
Reposted by Arthur Frouin
Le montant final officiel de ce #ZEVENT2025 s'élève donc à 16 179 096€ au profit des soignants et des patients.
Merci à tous pour votre énergie et votre générosité. 💚
Merci à tous pour votre énergie et votre générosité. 💚
September 7, 2025 at 11:21 PM
Le montant final officiel de ce #ZEVENT2025 s'élève donc à 16 179 096€ au profit des soignants et des patients.
Merci à tous pour votre énergie et votre générosité. 💚
Merci à tous pour votre énergie et votre générosité. 💚
Reposted by Arthur Frouin
My PhD student @leonielorenz.bsky.social (with Eva Geissen) has made this nice (free) online course to introduce mathematical modelling for biology:
www.ebi.ac.uk/training/onl...
Including both molecular and epidemiological examples
www.ebi.ac.uk/training/onl...
Including both molecular and epidemiological examples
Mathematical modelling for biologists - Modelling concepts in biological research
Mathematical modelling for biologists - Modelling concepts in biological research
www.ebi.ac.uk
August 15, 2025 at 10:39 AM
My PhD student @leonielorenz.bsky.social (with Eva Geissen) has made this nice (free) online course to introduce mathematical modelling for biology:
www.ebi.ac.uk/training/onl...
Including both molecular and epidemiological examples
www.ebi.ac.uk/training/onl...
Including both molecular and epidemiological examples
Reposted by Arthur Frouin
Metal ions are universally required for life, and many of the foundational principles of metal homeostasis have emerged from studies of microbial systems. In this review, I provide a introductory overview targeted to those new to the field.
#MicroSky #Metals
rdcu.be/eycU2
#MicroSky #Metals
rdcu.be/eycU2
Microbial metal physiology: ions to ecosystems
Nature Reviews Microbiology - Metal ions are required for all cells, and their homeostasis relies on ancient mechanisms that facilitate their import, distribution and storage. In this Review,...
rdcu.be
July 28, 2025 at 5:08 PM
Metal ions are universally required for life, and many of the foundational principles of metal homeostasis have emerged from studies of microbial systems. In this review, I provide a introductory overview targeted to those new to the field.
#MicroSky #Metals
rdcu.be/eycU2
#MicroSky #Metals
rdcu.be/eycU2
Reposted by Arthur Frouin
Avec #Framaspace, vos documents, agendas et contacts peuvent être entièrement synchronisés sur votre ordinateur ou smartphone ! 🔄
➡️ https://framaspace.org
➡️ https://framaspace.org
July 28, 2025 at 8:00 AM
Avec #Framaspace, vos documents, agendas et contacts peuvent être entièrement synchronisés sur votre ordinateur ou smartphone ! 🔄
➡️ https://framaspace.org
➡️ https://framaspace.org
Reposted by Arthur Frouin
🦠🧍♀️From bacterial to human immunity.
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
www.science.org
July 24, 2025 at 6:23 PM
🦠🧍♀️From bacterial to human immunity.
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
Reposted by Arthur Frouin
Postdoc (London, UK)
Research scientist to lead virus evolution and bioinformatic data analysis for wastewater surveillance of pandemic pathogens.
at Imperial College London
More details: http://iddjobs.org/jobs/2341
Research scientist to lead virus evolution and bioinformatic data analysis for wastewater surveillance of pandemic pathogens.
at Imperial College London
More details: http://iddjobs.org/jobs/2341
July 25, 2025 at 3:36 PM
Postdoc (London, UK)
Research scientist to lead virus evolution and bioinformatic data analysis for wastewater surveillance of pandemic pathogens.
at Imperial College London
More details: http://iddjobs.org/jobs/2341
Research scientist to lead virus evolution and bioinformatic data analysis for wastewater surveillance of pandemic pathogens.
at Imperial College London
More details: http://iddjobs.org/jobs/2341
Reposted by Arthur Frouin
My biggest, loudest job application advice:
WHY do you want this job? This SPECIFIC job? What about it interests you? What do you think of it? What can you bring to it?
I know this sounds obvious but a generic cover letter isn't doing you favours - really. *Show me you know the job!*
1/7
WHY do you want this job? This SPECIFIC job? What about it interests you? What do you think of it? What can you bring to it?
I know this sounds obvious but a generic cover letter isn't doing you favours - really. *Show me you know the job!*
1/7
July 25, 2025 at 12:09 PM
My biggest, loudest job application advice:
WHY do you want this job? This SPECIFIC job? What about it interests you? What do you think of it? What can you bring to it?
I know this sounds obvious but a generic cover letter isn't doing you favours - really. *Show me you know the job!*
1/7
WHY do you want this job? This SPECIFIC job? What about it interests you? What do you think of it? What can you bring to it?
I know this sounds obvious but a generic cover letter isn't doing you favours - really. *Show me you know the job!*
1/7
Reposted by Arthur Frouin
🌟 Exciting news! We’re launching three fully-funded postdoc positions for "New Horizons for Synthetic Phages”
Join us in tackling antimicrobial resistance with cutting-edge synthetic biology + AI bioinformatics. Based at Flinders Uni in vibrant Adelaide.
👇 Read on for details!
#Phage
Join us in tackling antimicrobial resistance with cutting-edge synthetic biology + AI bioinformatics. Based at Flinders Uni in vibrant Adelaide.
👇 Read on for details!
#Phage
July 25, 2025 at 8:15 AM
🌟 Exciting news! We’re launching three fully-funded postdoc positions for "New Horizons for Synthetic Phages”
Join us in tackling antimicrobial resistance with cutting-edge synthetic biology + AI bioinformatics. Based at Flinders Uni in vibrant Adelaide.
👇 Read on for details!
#Phage
Join us in tackling antimicrobial resistance with cutting-edge synthetic biology + AI bioinformatics. Based at Flinders Uni in vibrant Adelaide.
👇 Read on for details!
#Phage
Reposted by Arthur Frouin
🚨New pre-print 🚨
We introduce our new tool GOLD-GWAS and demonstrate its use by digging into the evolution of MRSA facilitated by SCCmec
This work was led by talented PhD student @seungwonko.bsky.social who did most of the computational heavylifting 1/n
www.biorxiv.org/content/10.1...
We introduce our new tool GOLD-GWAS and demonstrate its use by digging into the evolution of MRSA facilitated by SCCmec
This work was led by talented PhD student @seungwonko.bsky.social who did most of the computational heavylifting 1/n
www.biorxiv.org/content/10.1...
Genome co-adaptation and the evolution of methicillin resistant Staphylococcus aureus (MRSA)
Background: Antimicrobial resistance (AMR) in bacterial pathogens is a major threat to global health, rendering standard treatments ineffective and increasing the risk of severe infection or death. Re...
www.biorxiv.org
July 23, 2025 at 10:50 AM
🚨New pre-print 🚨
We introduce our new tool GOLD-GWAS and demonstrate its use by digging into the evolution of MRSA facilitated by SCCmec
This work was led by talented PhD student @seungwonko.bsky.social who did most of the computational heavylifting 1/n
www.biorxiv.org/content/10.1...
We introduce our new tool GOLD-GWAS and demonstrate its use by digging into the evolution of MRSA facilitated by SCCmec
This work was led by talented PhD student @seungwonko.bsky.social who did most of the computational heavylifting 1/n
www.biorxiv.org/content/10.1...
Reposted by Arthur Frouin
Scientists and engineers could:
Sequence the human genome
Put a man on the moon
Invent the internet
Solve protein folding problem
Decipher the complex immune system.
But fail to design a poster session in which you can actually hear the presenter.
In nearly every meeting out there.
Sequence the human genome
Put a man on the moon
Invent the internet
Solve protein folding problem
Decipher the complex immune system.
But fail to design a poster session in which you can actually hear the presenter.
In nearly every meeting out there.
July 23, 2025 at 10:56 AM
Scientists and engineers could:
Sequence the human genome
Put a man on the moon
Invent the internet
Solve protein folding problem
Decipher the complex immune system.
But fail to design a poster session in which you can actually hear the presenter.
In nearly every meeting out there.
Sequence the human genome
Put a man on the moon
Invent the internet
Solve protein folding problem
Decipher the complex immune system.
But fail to design a poster session in which you can actually hear the presenter.
In nearly every meeting out there.
Reposted by Arthur Frouin
I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!
Garud Lab
garud.eeb.ucla.edu
July 22, 2025 at 5:51 PM
I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!
Reposted by Arthur Frouin
🧵 Do you have R packages that make your workflow smoother or help you avoid problems you used to face all the time? I’ve collected a few that solved issues that used to trip me up 👇
July 18, 2025 at 7:09 PM
🧵 Do you have R packages that make your workflow smoother or help you avoid problems you used to face all the time? I’ve collected a few that solved issues that used to trip me up 👇
Reposted by Arthur Frouin
The overview of AMR that you always wanted (someone else to write) - amazing!
Truly brilliant paper with great figures! @lancetmicrobe.bsky.social
www.thelancet.com/journals/lan...
Truly brilliant paper with great figures! @lancetmicrobe.bsky.social
www.thelancet.com/journals/lan...
Antimicrobial resistance: a concise update
Antimicrobial resistance (AMR) is a serious threat to global public health, with approximately
5 million deaths associated with bacterial AMR in 2019. Tackling AMR requires a multifaceted
and cohesive...
www.thelancet.com
February 5, 2025 at 10:02 AM
The overview of AMR that you always wanted (someone else to write) - amazing!
Truly brilliant paper with great figures! @lancetmicrobe.bsky.social
www.thelancet.com/journals/lan...
Truly brilliant paper with great figures! @lancetmicrobe.bsky.social
www.thelancet.com/journals/lan...
Reposted by Arthur Frouin
Les signataires de la pétition contre la loi Dupont seront bientôt plus nombreux que les électeurs et électrices du parti de François Bayrou.
July 20, 2025 at 1:20 PM
Les signataires de la pétition contre la loi Dupont seront bientôt plus nombreux que les électeurs et électrices du parti de François Bayrou.
Reposted by Arthur Frouin
Finally online!
Our latest research is out @nature.com: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG
Our latest research is out @nature.com: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG
Non-antibiotics disrupt colonization resistance against enteropathogens
Nature - Non-antibiotic drugs from a wide range of therapeutic classes can alter the ability of gut commensals to resist invasion by enteropathogens, a previously underappreciated side effect of...
rdcu.be
July 16, 2025 at 9:20 PM
Finally online!
Our latest research is out @nature.com: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG
Our latest research is out @nature.com: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG
Reposted by Arthur Frouin
The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study - The Lancet Microbe www.thelancet.com/journals/lan...
The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study
Independent acquisition of plasmids and homoplastic mutations conferring antimicrobial
resistance have occurred repeatedly in multiple lineages of S Typhi, predominantly
arising in south Asia before s...
www.thelancet.com
July 15, 2025 at 8:30 PM
The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study - The Lancet Microbe www.thelancet.com/journals/lan...
Reposted by Arthur Frouin
Any favorite papers using or review papers on applying modern machine learning methods to human GWAS?
June 29, 2025 at 9:55 PM
Any favorite papers using or review papers on applying modern machine learning methods to human GWAS?
Reposted by Arthur Frouin
Reposted by Arthur Frouin
What determines who a phage can infect?
We tackled this question for temperate phages of Klebsiella — a bacterial pathogen — using a genome-wide association study (GWAS) and a massive protein testing effort.
👇 A thread!
We tackled this question for temperate phages of Klebsiella — a bacterial pathogen — using a genome-wide association study (GWAS) and a massive protein testing effort.
👇 A thread!
June 26, 2025 at 7:13 AM
What determines who a phage can infect?
We tackled this question for temperate phages of Klebsiella — a bacterial pathogen — using a genome-wide association study (GWAS) and a massive protein testing effort.
👇 A thread!
We tackled this question for temperate phages of Klebsiella — a bacterial pathogen — using a genome-wide association study (GWAS) and a massive protein testing effort.
👇 A thread!
Reposted by Arthur Frouin
Come and work with me and use the 53,897 samples of M. tuberculosis we have collated to help tackle this important disease!
We are part of the OxCoD4TB consortium that is developing new therapeutics for tuberculosis.
Grade 7, funding until 28 Feb 2028, deadline noon Fri 4 July
bit.ly/4ndKOhF
We are part of the OxCoD4TB consortium that is developing new therapeutics for tuberculosis.
Grade 7, funding until 28 Feb 2028, deadline noon Fri 4 July
bit.ly/4ndKOhF
Job Details
bit.ly
June 25, 2025 at 8:37 AM
Come and work with me and use the 53,897 samples of M. tuberculosis we have collated to help tackle this important disease!
We are part of the OxCoD4TB consortium that is developing new therapeutics for tuberculosis.
Grade 7, funding until 28 Feb 2028, deadline noon Fri 4 July
bit.ly/4ndKOhF
We are part of the OxCoD4TB consortium that is developing new therapeutics for tuberculosis.
Grade 7, funding until 28 Feb 2028, deadline noon Fri 4 July
bit.ly/4ndKOhF
Reposted by Arthur Frouin
PanVA: a visual analytics tool for pangenomic variant analysis https://www.biorxiv.org/content/10.1101/2025.06.23.661080v1
June 24, 2025 at 5:46 PM
PanVA: a visual analytics tool for pangenomic variant analysis https://www.biorxiv.org/content/10.1101/2025.06.23.661080v1
Reposted by Arthur Frouin
Interested in microbiome GWAS and heritability studies? Check out our new Review in Nature Reviews Genetics! We explore key findings, challenges, and future directions of the field.
rdcu.be/epoRR
@blekhman.bsky.social @sambhawa.bsky.social and Dr. Kelsey Johnson.
rdcu.be/epoRR
@blekhman.bsky.social @sambhawa.bsky.social and Dr. Kelsey Johnson.
Genomics of host–microbiome interactions in humans
Nature Reviews Genetics - In this Review, Ferretti et al. discuss advances in our understanding of interactions between the human genome and the microbiome, including the effects of the microbiome...
rdcu.be
June 4, 2025 at 4:52 PM
Interested in microbiome GWAS and heritability studies? Check out our new Review in Nature Reviews Genetics! We explore key findings, challenges, and future directions of the field.
rdcu.be/epoRR
@blekhman.bsky.social @sambhawa.bsky.social and Dr. Kelsey Johnson.
rdcu.be/epoRR
@blekhman.bsky.social @sambhawa.bsky.social and Dr. Kelsey Johnson.