Abid Hussain
@amh10.bsky.social
Medical Microbiologist & Clinical Services Director @UKHSA BPHL. All posts my own. #QI #ClinGov
An interesting role for faecal transplants rdcu.be/e1JKV
Fecal microbiota transplantation plus pembrolizumab and axitinib in metastatic renal cell carcinoma: the randomized phase 2 TACITO trial
Nature Medicine - In a double-blind, placebo-controlled phase 2 trial in patients with metastatic renal cell carcinoma treated with anti-PD-1 plus a VEGFR tyrosine kinase inhibitor, donor fecal...
rdcu.be
February 1, 2026 at 1:33 PM
An interesting role for faecal transplants rdcu.be/e1JKV
Bradyzoite subtypes rule the crossroads of Toxoplasma development rdcu.be/e1zCI
Bradyzoite subtypes rule the crossroads of Toxoplasma development
Nature Communications - The authors investigate the heterogeneity of Toxoplasma bradyzoites prior to recrudescence. Tissue cysts from infected mice harbor multiple bradyzoite subtypes with distinct...
rdcu.be
January 30, 2026 at 10:49 PM
Bradyzoite subtypes rule the crossroads of Toxoplasma development rdcu.be/e1zCI
Reposted by Abid Hussain
This online course presents the current knowledge on PK/PD of common antibiotics & antivirals, setting clinical breakpoints, individualised dosing & TDM. Innovative approaches for drug development also highlighted.
More: https://ow.ly/mszr50XXS9H
⏰Register by 09 March 2026!
#IDSky #clinmicro
More: https://ow.ly/mszr50XXS9H
⏰Register by 09 March 2026!
#IDSky #clinmicro
January 21, 2026 at 12:05 PM
This online course presents the current knowledge on PK/PD of common antibiotics & antivirals, setting clinical breakpoints, individualised dosing & TDM. Innovative approaches for drug development also highlighted.
More: https://ow.ly/mszr50XXS9H
⏰Register by 09 March 2026!
#IDSky #clinmicro
More: https://ow.ly/mszr50XXS9H
⏰Register by 09 March 2026!
#IDSky #clinmicro
Antibiotic Therapy for Uncomplicated Acute Appendicitis: jamanetwork.com/journals/jam...
Antibiotic Therapy for Uncomplicated Acute Appendicitis
This observational follow-up of patients in the Appendicitis Acuta multicenter randomized clinical trial conducted in Finland assesses the 10-year appendicitis recurrence and appendectomy rate in adul...
jamanetwork.com
January 21, 2026 at 8:49 PM
Antibiotic Therapy for Uncomplicated Acute Appendicitis: jamanetwork.com/journals/jam...
Albumin orchestrates a natural host defence mechanism against mucormycosis | Nature share.google/gKuxL49O8Fsj...
Albumin orchestrates a natural host defence mechanism against mucormycosis - Nature
Albumin selectively inhibits Mucorales growth through the release of bound free fatty acids.
share.google
January 18, 2026 at 6:50 AM
Albumin orchestrates a natural host defence mechanism against mucormycosis | Nature share.google/gKuxL49O8Fsj...
The hidden link between cefiderocol resistance and increased virulence in Klebsiella pneumoniae: Insights from a TraDIS-based investigation - Clinical Microbiology and Infection www.clinicalmicrobiologyandinfection.org/article/S119...
The hidden link between cefiderocol resistance and increased virulence in Klebsiella pneumoniae: Insights from a TraDIS-based investigation
The emergence of extensively drug-resistant Enterobacterales, particularly carbapenemase-producing
Klebsiella pneumoniae, poses a serious global health threat. Cefiderocol (FDC), a
sideromycin antibio...
www.clinicalmicrobiologyandinfection.org
December 21, 2025 at 9:20 AM
The hidden link between cefiderocol resistance and increased virulence in Klebsiella pneumoniae: Insights from a TraDIS-based investigation - Clinical Microbiology and Infection www.clinicalmicrobiologyandinfection.org/article/S119...
Reposted by Abid Hussain
In high-risk febrile neutropenic patients, an AMS bundle safely reduced broad-spectrum antibiotic use, shifting from MEM to CAZ and shortening treatment duration
A meaningful step forward in #AntimicrobialStewardship in high-risk populations
doi.org/10.1093/jaca...
#JACAMRNews #IDSky
A meaningful step forward in #AntimicrobialStewardship in high-risk populations
doi.org/10.1093/jaca...
#JACAMRNews #IDSky
Impact of an antimicrobial stewardship bundle on the outcome of high-risk neutropenic patients with fever: a pre-post study
AbstractBackground. Rapid antibiotic initiation is essential for managing potential infections following chemotherapy-induced neutropenia. However, excessi
doi.org
December 4, 2025 at 11:02 AM
In high-risk febrile neutropenic patients, an AMS bundle safely reduced broad-spectrum antibiotic use, shifting from MEM to CAZ and shortening treatment duration
A meaningful step forward in #AntimicrobialStewardship in high-risk populations
doi.org/10.1093/jaca...
#JACAMRNews #IDSky
A meaningful step forward in #AntimicrobialStewardship in high-risk populations
doi.org/10.1093/jaca...
#JACAMRNews #IDSky
The key question is, where does Emblaveo fit when chosing empirical therapy?https://link.springer.com/article/10.1007/s40265-025-02258-x
Aztreonam-Avibactam: A Review in the Treatment of Serious Bacterial Infections Caused by Aerobic Gram-Negative Organisms - Drugs
Aztreonam-avibactam (Emblaveo™), a fixed-dose combination of the monobactam antibacterial agent aztreonam and the broad-spectrum β-lactamase inhibitor avibactam, has been developed as a treatment, adm...
link.springer.com
November 22, 2025 at 8:19 PM
The key question is, where does Emblaveo fit when chosing empirical therapy?https://link.springer.com/article/10.1007/s40265-025-02258-x
My thoughts on AMS and where we are heading: www.linkedin.com/pulse/stewar...
Stewardship 2.0: Harnessing Data, Tech, and Teamwork to Save Antibiotics
When we think about the rise of antibiotic-resistant superbugs, our minds typically go to one place: the unwell patient. The prevailing wisdom is that antimicrobial resistance (AMR) is a direct conseq...
www.linkedin.com
October 4, 2025 at 7:25 PM
My thoughts on AMS and where we are heading: www.linkedin.com/pulse/stewar...
Resolving a NICU outbreak of meticillin-resistant Staphylococcus aureus to the single-nucleotide variant level using Oxford Nanopore simplex reads and HERRO error correction www.journalofhospitalinfection.com/article/S019... @alanmcn1.bsky.social @wvschaik.bsky.social @jessicamablair.bsky.social
Resolving a neonatal intensive care unit outbreak of meticillin-resistant Staphylococcus aureus to the single-nucleotide variant level using Oxford Nanopore simplex reads and HERRO error correction
Our laboratory began prospective genomic surveillance for healthcare-associated organisms
in 2022 using Oxford Nanopore Technologies (ONT) as a standalone platform. While effective
for early outbreak ...
www.journalofhospitalinfection.com
September 6, 2025 at 7:01 PM
Resolving a NICU outbreak of meticillin-resistant Staphylococcus aureus to the single-nucleotide variant level using Oxford Nanopore simplex reads and HERRO error correction www.journalofhospitalinfection.com/article/S019... @alanmcn1.bsky.social @wvschaik.bsky.social @jessicamablair.bsky.social
Advancements in urinary tract infections: understanding, prevention, diagnosis, and treatment doi.org/10.1177/2049...
Advancements in urinary tract infections: understanding, prevention, diagnosis, and treatment - Bhaskar K. Somani, 2025
doi.org
September 6, 2025 at 6:51 PM
Advancements in urinary tract infections: understanding, prevention, diagnosis, and treatment doi.org/10.1177/2049...
Empiric antibiotics for moderate-severe community-Acquired Pneumonia: We ought to serve patients better! - More studies needed www.clinicalmicrobiologyandinfection.org/article/S119...
Empiric antibiotics for moderate-severe community-Acquired Pneumonia: We ought to serve patients better!
Each day thousands of patients are hospitalized worldwide with Community-Acquired
Pneumonia (CAP), either radiologically confirmed or presumed based on clinical symptoms
only, and each day physicians ...
www.clinicalmicrobiologyandinfection.org
September 6, 2025 at 6:49 PM
Empiric antibiotics for moderate-severe community-Acquired Pneumonia: We ought to serve patients better! - More studies needed www.clinicalmicrobiologyandinfection.org/article/S119...
Reposted by Abid Hussain
Read this properly now and it really is a staggeringly beautiful study. And super important. Opens a new avenue of research I reckon. One of my papers of the year.
So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!
Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters
Uridine boosts aminoglycoside treatment efficiency against antibiotic-susceptible as well as antibiotic-resistant E. coli strains.
www.science.org
September 6, 2025 at 6:43 PM
Read this properly now and it really is a staggeringly beautiful study. And super important. Opens a new avenue of research I reckon. One of my papers of the year.
Cardiac Manifestations of Mycoplasma pneumoniae Infections: A Cohort Study 2007–2024 url: academic.oup.com/cid/article/...
Cardiac Manifestations of Mycoplasma pneumoniae Infections: A Cohort Study 2007–2024
A 17-year cohort shows higher incidence of cardiac involvement than previously reported in patients admitted with Mycoplasma pneumoniae infections that may
academic.oup.com
September 6, 2025 at 6:44 PM
Cardiac Manifestations of Mycoplasma pneumoniae Infections: A Cohort Study 2007–2024 url: academic.oup.com/cid/article/...
Teicoplanin total trough concentration and adverse effects in patients with hypoalbuminemia - Journal of Infection and Chemotherapy www.jiac-j.com/article/S134...
Teicoplanin total trough concentration and adverse effects in patients with hypoalbuminemia
The association between Teicoplanin (TEIC) total trough concentration (Cmin) and adverse
effects (hepatotoxicity, nephrotoxicity, and thrombocytopenia) in patients with hypoalbuminemia
remains poorly ...
www.jiac-j.com
September 6, 2025 at 6:40 PM
Teicoplanin total trough concentration and adverse effects in patients with hypoalbuminemia - Journal of Infection and Chemotherapy www.jiac-j.com/article/S134...
The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study - The Lancet Microbe www.thelancet.com/journals/lan...
The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study
Independent acquisition of plasmids and homoplastic mutations conferring antimicrobial
resistance have occurred repeatedly in multiple lineages of S Typhi, predominantly
arising in south Asia before s...
www.thelancet.com
July 15, 2025 at 8:30 PM
The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study - The Lancet Microbe www.thelancet.com/journals/lan...
Reposted by Abid Hussain
To tackle antibiotic resistance (#AMR) in newborns, especially premature babies in #NICUs, researchers explored the best trial design for studying #IPC.
See what this simulation study, based on #NeoIPC data and presented at #ESCMIDGlobal, suggests 👇
View poster: neoipc.org/wp-content/u...
See what this simulation study, based on #NeoIPC data and presented at #ESCMIDGlobal, suggests 👇
View poster: neoipc.org/wp-content/u...
April 18, 2025 at 2:35 PM
To tackle antibiotic resistance (#AMR) in newborns, especially premature babies in #NICUs, researchers explored the best trial design for studying #IPC.
See what this simulation study, based on #NeoIPC data and presented at #ESCMIDGlobal, suggests 👇
View poster: neoipc.org/wp-content/u...
See what this simulation study, based on #NeoIPC data and presented at #ESCMIDGlobal, suggests 👇
View poster: neoipc.org/wp-content/u...
Candida diagnostics in endovascular infections. Is @brukercorporation.bsky.social #MALDI better for Candida pararugosa? #ESCMID2025
April 15, 2025 at 9:31 AM
Candida diagnostics in endovascular infections. Is @brukercorporation.bsky.social #MALDI better for Candida pararugosa? #ESCMID2025