Nathalie J Arhel
@arhelnathalie.bsky.social
CNRS research director, McGill visiting professor 🇬🇧🇫🇷🇨🇦, nuclear trafficking, viruses, innate immunity
Reposted by Nathalie J Arhel
Excited to be co-organizing this @embo.org Workshop on #Pathogen #Immunity and #Signalling next June 8-12 2026 in Leiden! 🥳🥳🥳 #Savethedate
Join us for this exciting meeting! @embo.org Workshop "Pathogen Immunity and Signalling", 8-12 June, 2026, Leiden, The Netherlands meetings.embo.org/event/26-pat...
October 18, 2025 at 5:05 PM
Excited to be co-organizing this @embo.org Workshop on #Pathogen #Immunity and #Signalling next June 8-12 2026 in Leiden! 🥳🥳🥳 #Savethedate
Reposted by Nathalie J Arhel
Over the last year, Nature’s Careers team has been tapping into its global community of readers, writers, friends and colleagues to compile a list of laboratory hacks to help make scientists’ working lives easier. Here’s a list of 99 of those hacks. #Academicsky 🧪
These 99 'lab hacks' will make your scientific work easier
Nature asked contributors, editors and working researchers to share their best advice for scientists.
go.nature.com
October 6, 2025 at 1:28 AM
Over the last year, Nature’s Careers team has been tapping into its global community of readers, writers, friends and colleagues to compile a list of laboratory hacks to help make scientists’ working lives easier. Here’s a list of 99 of those hacks. #Academicsky 🧪
RANBP2 is a major susceptibility factor in Acute Necrotizing Encephalopathy. But is it a single protein, or are there other isoforms with distinct roles we should be studying?
@sdesgraupes.bsky.social @aneinternational.bsky.social @irim-life.bsky.social
www.sciencedirect.com/science/arti...
@sdesgraupes.bsky.social @aneinternational.bsky.social @irim-life.bsky.social
www.sciencedirect.com/science/arti...
Unravelling the diversity of RANBP2: protein isoforms and implications for cellular function and human disease
RANBP2 (also known as Nup358) is the largest nucleoporin of the nuclear pore complex (NPC), where it constitutes the main component of the cytoplasmic…
www.sciencedirect.com
September 28, 2025 at 11:35 PM
RANBP2 is a major susceptibility factor in Acute Necrotizing Encephalopathy. But is it a single protein, or are there other isoforms with distinct roles we should be studying?
@sdesgraupes.bsky.social @aneinternational.bsky.social @irim-life.bsky.social
www.sciencedirect.com/science/arti...
@sdesgraupes.bsky.social @aneinternational.bsky.social @irim-life.bsky.social
www.sciencedirect.com/science/arti...
Reposted by Nathalie J Arhel
2023 HPAI outbreak in South American Sea Lions: atypically high number of abortions + abnormal reproductive behaviours: including males retaining and mounting females outside the breeding season + necrophilia
👉 revistas.unal.edu.co/index.php/ac...
👉 revistas.unal.edu.co/index.php/ac...
September 5, 2025 at 1:08 AM
2023 HPAI outbreak in South American Sea Lions: atypically high number of abortions + abnormal reproductive behaviours: including males retaining and mounting females outside the breeding season + necrophilia
👉 revistas.unal.edu.co/index.php/ac...
👉 revistas.unal.edu.co/index.php/ac...
Reposted by Nathalie J Arhel
A new study in JAMA has examined a rare but severe complication that can occur in children who contract the flu. This complication, called acute necrotizing encephalopathy, or ANE, carries a mortality rate of 27% despite intensive care and treatment, according to the new research. cnn.it/4lzElLI
August 19, 2025 at 6:51 PM
A new study in JAMA has examined a rare but severe complication that can occur in children who contract the flu. This complication, called acute necrotizing encephalopathy, or ANE, carries a mortality rate of 27% despite intensive care and treatment, according to the new research. cnn.it/4lzElLI
Reposted by Nathalie J Arhel
Evidence is growing that some HIV-infected infants, if given antiretroviral drugs early in life, are able to suppress their viral loads to undetectable levels and then come off the medicine. www.wired.com/story/the-fi...
The First Widespread Cure for HIV Could Be in Children
Evidence is growing that some HIV-infected infants, if given antiretroviral drugs early in life, are able to suppress their viral loads to undetectable levels and then come off the medicine.
www.wired.com
August 1, 2025 at 1:23 PM
Evidence is growing that some HIV-infected infants, if given antiretroviral drugs early in life, are able to suppress their viral loads to undetectable levels and then come off the medicine. www.wired.com/story/the-fi...
Reposted by Nathalie J Arhel
ANE: The Brain Emergency Every Doctor Should Recognize.
#AcuteNecrotizingEncephalopathy
#ANEAwareness #ANE1 #SickKidsToronto #PediatricNeurology #Influenza #BrainHealth #EmergencyPediatrics #RareDiseaseAwareness #ViralEncephalopathy
@arhelnathalie.bsky.social
m.youtube.com/watch?v=ywrf...
#AcuteNecrotizingEncephalopathy
#ANEAwareness #ANE1 #SickKidsToronto #PediatricNeurology #Influenza #BrainHealth #EmergencyPediatrics #RareDiseaseAwareness #ViralEncephalopathy
@arhelnathalie.bsky.social
m.youtube.com/watch?v=ywrf...
ANE Clinical Overview: Symptoms, Diagnosis, and Treatment | Dr. E. Ann Yeh at ANEmone 2025
YouTube video by ANE International
m.youtube.com
July 30, 2025 at 10:46 AM
ANE: The Brain Emergency Every Doctor Should Recognize.
#AcuteNecrotizingEncephalopathy
#ANEAwareness #ANE1 #SickKidsToronto #PediatricNeurology #Influenza #BrainHealth #EmergencyPediatrics #RareDiseaseAwareness #ViralEncephalopathy
@arhelnathalie.bsky.social
m.youtube.com/watch?v=ywrf...
#AcuteNecrotizingEncephalopathy
#ANEAwareness #ANE1 #SickKidsToronto #PediatricNeurology #Influenza #BrainHealth #EmergencyPediatrics #RareDiseaseAwareness #ViralEncephalopathy
@arhelnathalie.bsky.social
m.youtube.com/watch?v=ywrf...
Reposted by Nathalie J Arhel
The @sierralab.bsky.social lab is hiring!
Postdoctoral position in #microglial development (#IKUR)
www.achucarro.org/job/postdoct...
Postdoctoral position in #microglial development (#IKUR)
www.achucarro.org/job/postdoct...
July 14, 2025 at 9:57 AM
The @sierralab.bsky.social lab is hiring!
Postdoctoral position in #microglial development (#IKUR)
www.achucarro.org/job/postdoct...
Postdoctoral position in #microglial development (#IKUR)
www.achucarro.org/job/postdoct...
Reposted by Nathalie J Arhel
Are you interested in human brain #organoids to study #microglia but don't know where to start?🧠🧪
#neuroskyence
Here's our piece of advice on "Building Immunocompetent Cerebral Organoids From a Developmental Perspective"
onlinelibrary.wiley.com/doi/10.1002/...
#neuroskyence
Here's our piece of advice on "Building Immunocompetent Cerebral Organoids From a Developmental Perspective"
onlinelibrary.wiley.com/doi/10.1002/...
Building Immunocompetent Cerebral Organoids From a Developmental Perspective
Conventional cerebral organoids do not contain microglia, which must be added.
We propose recommendations to assess microglial immunocompetence using quantitative approaches and stringent statist...
onlinelibrary.wiley.com
July 24, 2025 at 7:19 AM
Are you interested in human brain #organoids to study #microglia but don't know where to start?🧠🧪
#neuroskyence
Here's our piece of advice on "Building Immunocompetent Cerebral Organoids From a Developmental Perspective"
onlinelibrary.wiley.com/doi/10.1002/...
#neuroskyence
Here's our piece of advice on "Building Immunocompetent Cerebral Organoids From a Developmental Perspective"
onlinelibrary.wiley.com/doi/10.1002/...
In this piece, I reflect on how research agendas, funding structures and publishing ecosystems are dominated by a few wealthy countries, and outline concrete steps we could take to redress inequities.
#EquitableScience #GlobalHealth #ResearchJustice #DecolonizingScience
#EquitableScience #GlobalHealth #ResearchJustice #DecolonizingScience
Read the latest opinion piece by @arhelnathalie.bsky.social on global health! journals.plos.org/globalpublic...
Fostering better science by releasing biomedical research and innovation from the grip of rich nations
journals.plos.org
July 4, 2025 at 4:41 AM
In this piece, I reflect on how research agendas, funding structures and publishing ecosystems are dominated by a few wealthy countries, and outline concrete steps we could take to redress inequities.
#EquitableScience #GlobalHealth #ResearchJustice #DecolonizingScience
#EquitableScience #GlobalHealth #ResearchJustice #DecolonizingScience
Reposted by Nathalie J Arhel
Vaccine Integrity Project has been created at the University of Minnesota to counter misinformation and a concern about data manipulation by current HHS leadership. 🧪
www.science.org/content/arti...
www.science.org/content/arti...
Vaccine experts band together to counter U.S. government misinformation
Vaccine Integrity Project intends to provide scientific responses to ill-founded vaccine moves
www.science.org
April 29, 2025 at 1:52 PM
Vaccine Integrity Project has been created at the University of Minnesota to counter misinformation and a concern about data manipulation by current HHS leadership. 🧪
www.science.org/content/arti...
www.science.org/content/arti...
Starting tomorrow!
Topic: ANEmone
Time: Apr 28, 2025 08:30 AM Paris
Join Zoom Meeting
umontpellier-fr.zoom.us/j/9545768422...
Meeting ID: 954 5768 4221
Passcode: 991470
Topic: ANEmone
Time: Apr 28, 2025 08:30 AM Paris
Join Zoom Meeting
umontpellier-fr.zoom.us/j/9545768422...
Meeting ID: 954 5768 4221
Passcode: 991470
April 27, 2025 at 9:35 PM
Starting tomorrow!
Topic: ANEmone
Time: Apr 28, 2025 08:30 AM Paris
Join Zoom Meeting
umontpellier-fr.zoom.us/j/9545768422...
Meeting ID: 954 5768 4221
Passcode: 991470
Topic: ANEmone
Time: Apr 28, 2025 08:30 AM Paris
Join Zoom Meeting
umontpellier-fr.zoom.us/j/9545768422...
Meeting ID: 954 5768 4221
Passcode: 991470
Reposted by Nathalie J Arhel
Super excited for the ANEmone colloque tomorrow reuniting families, clinicians and scientists in order to better understand ANE1 !
@arhelnathalie.bsky.social
@arhelnathalie.bsky.social
April 27, 2025 at 6:28 PM
Super excited for the ANEmone colloque tomorrow reuniting families, clinicians and scientists in order to better understand ANE1 !
@arhelnathalie.bsky.social
@arhelnathalie.bsky.social
Reposted by Nathalie J Arhel
Five years on: how COVID was the catalyst for Africa’s genomic revolution “We built a culture of collaboration, not competition,” Read more of this piece in Nature at the gem - issuu.com/the.gem/docs... #Genomics #Africa #Fellowship
April 8, 2025 at 5:16 AM
Five years on: how COVID was the catalyst for Africa’s genomic revolution “We built a culture of collaboration, not competition,” Read more of this piece in Nature at the gem - issuu.com/the.gem/docs... #Genomics #Africa #Fellowship
Reposted by Nathalie J Arhel
My art is based on my experiences of breast cancer. I’ll have a book out later this year. I am fully confident that AI could not replicate an expression of something that’s a deeply human experience.
March 28, 2025 at 10:20 AM
My art is based on my experiences of breast cancer. I’ll have a book out later this year. I am fully confident that AI could not replicate an expression of something that’s a deeply human experience.
Reposted by Nathalie J Arhel
RANBP2 regulates influenza RNA replication and nuclear export, triggering hyper-inflammation, offering insight into Acute Necrotizing Encephalopathy pathogenesis
doi.org/10.1101/2025...
doi.org/10.1101/2025...
March 26, 2025 at 2:04 AM
RANBP2 regulates influenza RNA replication and nuclear export, triggering hyper-inflammation, offering insight into Acute Necrotizing Encephalopathy pathogenesis
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Reposted by Nathalie J Arhel
The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infection https://www.biorxiv.org/content/10.1101/2025.03.23.644734v1
March 25, 2025 at 9:15 PM
The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infection https://www.biorxiv.org/content/10.1101/2025.03.23.644734v1
Our latest collaborative study with the Pasteur Institute and University of Toronto on the role of RANBP2 in #influenza -associated hyperinflammation #AcuteNecrotizingEncephalopathy @aneinternational.bsky.social @ribonucleicacids.bsky.social @irim-life.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infection
Influenza virus infections can cause severe complications such as Acute Necrotizing Encephalopathy (ANE), which is characterised by rapid onset pathological inflammation following febrile infection. H...
www.biorxiv.org
March 28, 2025 at 10:20 AM
Our latest collaborative study with the Pasteur Institute and University of Toronto on the role of RANBP2 in #influenza -associated hyperinflammation #AcuteNecrotizingEncephalopathy @aneinternational.bsky.social @ribonucleicacids.bsky.social @irim-life.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Latest paper from the VTRIS team @irim-life.bsky.social @umontpellier.bsky.social 👏👏👏
🚨 New publication in @PNAS!
Our team @irim-life.bsky.social identifies MITD1 as a brain-specific ISG that blocks the replication of neurotropic flaviviruses (WNV, ZIKV, USUV...) in microglia! 🧠🦠
@inserm.fr @cnrsbiologie.bsky.social
www-pnas-org.proxy.insermbiblio.inist.fr/doi/10.1073/...
Our team @irim-life.bsky.social identifies MITD1 as a brain-specific ISG that blocks the replication of neurotropic flaviviruses (WNV, ZIKV, USUV...) in microglia! 🧠🦠
@inserm.fr @cnrsbiologie.bsky.social
www-pnas-org.proxy.insermbiblio.inist.fr/doi/10.1073/...
March 21, 2025 at 1:15 PM
Latest paper from the VTRIS team @irim-life.bsky.social @umontpellier.bsky.social 👏👏👏
Reposted by Nathalie J Arhel
#Kenya: Kala-azar is the second deadliest parasitic disease after malaria, with a 95% death rate if untreated.
With rising cases reported since September, and three reported deaths since, MSF teams are on the ground supporting the Ministry of Health in an emergency response.
With rising cases reported since September, and three reported deaths since, MSF teams are on the ground supporting the Ministry of Health in an emergency response.
March 14, 2025 at 3:16 PM
#Kenya: Kala-azar is the second deadliest parasitic disease after malaria, with a 95% death rate if untreated.
With rising cases reported since September, and three reported deaths since, MSF teams are on the ground supporting the Ministry of Health in an emergency response.
With rising cases reported since September, and three reported deaths since, MSF teams are on the ground supporting the Ministry of Health in an emergency response.
Reposted by Nathalie J Arhel
Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n
Homepage - openRxiv
openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.
openrxiv.org
March 11, 2025 at 1:20 PM
Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n
Reposted by Nathalie J Arhel
you’re fired. wait you’re rehired. email us a list of things you’ve done today wait forget it you’re fired again. come back your job was important. you’re fired. or hired. come in to the office. wait the office has no computers go home. we are the department of government efficiency.
March 5, 2025 at 10:34 PM
you’re fired. wait you’re rehired. email us a list of things you’ve done today wait forget it you’re fired again. come back your job was important. you’re fired. or hired. come in to the office. wait the office has no computers go home. we are the department of government efficiency.
Reposted by Nathalie J Arhel
#Gaza: Doctors Without Borders strongly denounces Israel’s announcement to block aid into Gaza. Humanitarian aid should never be used as a tool of war.
Regardless of negotiations between warring parties, people in Gaza still need an immediate and massive scale-up of humanitarian supplies.
Regardless of negotiations between warring parties, people in Gaza still need an immediate and massive scale-up of humanitarian supplies.
March 3, 2025 at 1:44 PM
#Gaza: Doctors Without Borders strongly denounces Israel’s announcement to block aid into Gaza. Humanitarian aid should never be used as a tool of war.
Regardless of negotiations between warring parties, people in Gaza still need an immediate and massive scale-up of humanitarian supplies.
Regardless of negotiations between warring parties, people in Gaza still need an immediate and massive scale-up of humanitarian supplies.
Reposted by Nathalie J Arhel
Today, a broad coalition of scientific professional societies who represent over 92,000 scientists are speaking out against the politicization and demonization of Federally funded science and government scientist jobs.
It was an honor to help the Union of Concerned Scientists with this! 🧪🌎
It was an honor to help the Union of Concerned Scientists with this! 🧪🌎
48 Scientific Societies Representing Almost 100,000 Scientists Ask Congress to Protect the Future of Science
48 scientific societies representing almost 100,000 scientists signed on to a letter asking Congress to protect the future of science
www.ucsusa.org
March 3, 2025 at 3:52 PM
Today, a broad coalition of scientific professional societies who represent over 92,000 scientists are speaking out against the politicization and demonization of Federally funded science and government scientist jobs.
It was an honor to help the Union of Concerned Scientists with this! 🧪🌎
It was an honor to help the Union of Concerned Scientists with this! 🧪🌎