Sophie Desgraupes
@sdesgraupes.bsky.social
Postdoctoral fellow in Arhel lab at IRIM institute, studying the role of RanBP2 in acute necrotizing encephalopathy following IAV infection 🦠🧬
Reposted by Sophie Desgraupes
RANBP2 is a major susceptibility factor in Acute Necrotizing Encephalopathy. But is it a single protein, or are there other isoforms with distinct roles we should be studying?
@sdesgraupes.bsky.social @aneinternational.bsky.social @irim-life.bsky.social
www.sciencedirect.com/science/arti...
@sdesgraupes.bsky.social @aneinternational.bsky.social @irim-life.bsky.social
www.sciencedirect.com/science/arti...
Unravelling the diversity of RANBP2: protein isoforms and implications for cellular function and human disease
RANBP2 (also known as Nup358) is the largest nucleoporin of the nuclear pore complex (NPC), where it constitutes the main component of the cytoplasmic…
www.sciencedirect.com
September 28, 2025 at 11:35 PM
RANBP2 is a major susceptibility factor in Acute Necrotizing Encephalopathy. But is it a single protein, or are there other isoforms with distinct roles we should be studying?
@sdesgraupes.bsky.social @aneinternational.bsky.social @irim-life.bsky.social
www.sciencedirect.com/science/arti...
@sdesgraupes.bsky.social @aneinternational.bsky.social @irim-life.bsky.social
www.sciencedirect.com/science/arti...
Super excited for the ANEmone colloque tomorrow reuniting families, clinicians and scientists in order to better understand ANE1 !
@arhelnathalie.bsky.social
@arhelnathalie.bsky.social
April 27, 2025 at 6:28 PM
Super excited for the ANEmone colloque tomorrow reuniting families, clinicians and scientists in order to better understand ANE1 !
@arhelnathalie.bsky.social
@arhelnathalie.bsky.social
Reposted by Sophie Desgraupes
Acute Necrotising Encephalopathy 1 is a rare disease that triggers devastating brain damage in young children following a viral infection. Please would you consider giving to help 19 kids with ANE1 from 🇺🇸🇨🇦🇪🇺 attend a science-patient conference in 2025 🙏 #GivingTuesday
fondsguilhem.fr/projet/souti...
fondsguilhem.fr/projet/souti...
Soutien à l'organisation d'une rencontre de patients atteints d'ANE1 - fonds guilhem
En avril prochain, cet événement aura pour but de promouvoir un partage d’expériences et d'apporter un soutien grâce à la rencontre entre familles, chercheurs et médecins autour de l'ANE1.
fondsguilhem.fr
December 3, 2024 at 11:48 AM
Acute Necrotising Encephalopathy 1 is a rare disease that triggers devastating brain damage in young children following a viral infection. Please would you consider giving to help 19 kids with ANE1 from 🇺🇸🇨🇦🇪🇺 attend a science-patient conference in 2025 🙏 #GivingTuesday
fondsguilhem.fr/projet/souti...
fondsguilhem.fr/projet/souti...
Reposted by Sophie Desgraupes
RANBP2 regulates influenza RNA replication and nuclear export, triggering hyper-inflammation, offering insight into Acute Necrotizing Encephalopathy pathogenesis
doi.org/10.1101/2025...
doi.org/10.1101/2025...
March 26, 2025 at 2:04 AM
RANBP2 regulates influenza RNA replication and nuclear export, triggering hyper-inflammation, offering insight into Acute Necrotizing Encephalopathy pathogenesis
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Reposted by Sophie Desgraupes
The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infection https://www.biorxiv.org/content/10.1101/2025.03.23.644734v1
March 25, 2025 at 9:15 PM
The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infection https://www.biorxiv.org/content/10.1101/2025.03.23.644734v1
Reposted by Sophie Desgraupes
Our latest collaborative study with the Pasteur Institute and University of Toronto on the role of RANBP2 in #influenza -associated hyperinflammation #AcuteNecrotizingEncephalopathy @aneinternational.bsky.social @ribonucleicacids.bsky.social @irim-life.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infection
Influenza virus infections can cause severe complications such as Acute Necrotizing Encephalopathy (ANE), which is characterised by rapid onset pathological inflammation following febrile infection. H...
www.biorxiv.org
March 28, 2025 at 10:20 AM
Our latest collaborative study with the Pasteur Institute and University of Toronto on the role of RANBP2 in #influenza -associated hyperinflammation #AcuteNecrotizingEncephalopathy @aneinternational.bsky.social @ribonucleicacids.bsky.social @irim-life.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...