Ankita Jha
@ankita13jha.bsky.social
Cancer cell biologist, Research Associate @Clare Waterman lab, Blebs are life or death!!! LOVE to torture..Oops confine cells.. All about cell migration 😀 views are my own, not of employer
Pinned
Ankita Jha
@ankita13jha.bsky.social
· Mar 10
CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb-based migration
Cells under high confinement form highly polarized hydrostatic pressure-driven, stable leader blebs that enable efficient migration in low adhesion, environments. Here we investigated the basis of the...
www.biorxiv.org
As scientist I am going through difficult times (this is understatement of the year for me!!). Past one and half months have been horrible, however I am trying to pick myself up and super excited to share my postdoc work with the community! #cellmigration
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Ankita Jha
When ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants.
Age and gender distortion in online media and large language models - Nature
Stereotypes of age-related gender bias are socially distorted, as evidenced by the age gap in the representations of women and men across various media and algorithms, despite no systematic age differ...
www.nature.com
November 2, 2025 at 9:47 PM
When ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants.
It's always lovely to see you 💕 @thomaslecuit.bsky.social
It's amazing how some things never change and we like it that way 😀
It's amazing how some things never change and we like it that way 😀
October 23, 2025 at 8:05 AM
It's always lovely to see you 💕 @thomaslecuit.bsky.social
It's amazing how some things never change and we like it that way 😀
It's amazing how some things never change and we like it that way 😀
Yeiii to a friend!!!!!
Thrilled to announce the launch of my lab
@cri-utsw.bsky.social at UTSW this January!
We will explore how cells sense and respond to mechanical forces, focusing on membrane mechanics to reveal how tension and signaling work together to shape cell behavior.
@cri-utsw.bsky.social at UTSW this January!
We will explore how cells sense and respond to mechanical forces, focusing on membrane mechanics to reveal how tension and signaling work together to shape cell behavior.
We're growing! Our newest Investigator @henrydebelly.bsky.social will join the CRI Tissue #Regeneration Program in January 2026. Learn more about Henry ➡️ cri.utsw.edu/faculty/henr... and 📌apply to research in his lab cri.utsw.edu/careers
October 16, 2025 at 11:30 PM
Yeiii to a friend!!!!!
Reposted by Ankita Jha
🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
October 16, 2025 at 6:23 AM
🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
Reposted by Ankita Jha
A summary of training, fellowship, and career development awards
Fiscal year 2025 (compared to fiscal year 2024)
1/12
Fiscal year 2025 (compared to fiscal year 2024)
1/12
a dog is sitting on a rug in front of a brick wall and a plant .
ALT: a dog is sitting on a rug in front of a brick wall and a plant .
media.tenor.com
October 16, 2025 at 12:25 AM
A summary of training, fellowship, and career development awards
Fiscal year 2025 (compared to fiscal year 2024)
1/12
Fiscal year 2025 (compared to fiscal year 2024)
1/12
Reposted by Ankita Jha
Reposted by Ankita Jha
I have been slacking on the #microscreepy season! Thanks for reposting!
October 5, 2025 at 9:20 PM
I have been slacking on the #microscreepy season! Thanks for reposting!
Also you can do crazy awesome imaging and then put googly eyes on them during Halloween season!!
PhD or Master's position available for Fall 2026!
Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont...
Please share!
Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont...
Please share!
October 5, 2025 at 7:00 PM
Also you can do crazy awesome imaging and then put googly eyes on them during Halloween season!!
Reposted by Ankita Jha
PhD or Master's position available for Fall 2026!
Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont...
Please share!
Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont...
Please share!
October 5, 2025 at 5:29 PM
PhD or Master's position available for Fall 2026!
Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont...
Please share!
Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont...
Please share!
Reposted by Ankita Jha
If anyone ever wants to brush up on a lot of cell migration concepts don't forget we have several wonderful scientists who have given talks previously in cell migration seminars. I find it so comforting to go look at old videos, maybe someone else who will do as well!!
youtube.com/@cellmigrati...
youtube.com/@cellmigrati...
Cell Migration Seminars
Cell Migration Seminars every Tuesday at 16:00 BST.
youtube.com
September 29, 2025 at 1:48 AM
If anyone ever wants to brush up on a lot of cell migration concepts don't forget we have several wonderful scientists who have given talks previously in cell migration seminars. I find it so comforting to go look at old videos, maybe someone else who will do as well!!
youtube.com/@cellmigrati...
youtube.com/@cellmigrati...
Reposted by Ankita Jha
we found that nuclear envelope rupture triggers rapid DIAPH3 formin influx to generate a actin mesh to prevent further chromatin leakage from damaged nuclei. thanks to Pitter Huesgen @degradomics.bsky.social and @cibss.bsky.social, @chrkam.bsky.social
September 22, 2025 at 11:00 AM
we found that nuclear envelope rupture triggers rapid DIAPH3 formin influx to generate a actin mesh to prevent further chromatin leakage from damaged nuclei. thanks to Pitter Huesgen @degradomics.bsky.social and @cibss.bsky.social, @chrkam.bsky.social
Thank you!!
More on cell polarity and migration! Ankita Jha from NIH revealed how the spatial arrangement of signalling molecules by picket proteins controls a gradient of EGFR and PI3K activity that drives bleb-based migration, often used by tumour cells to metastasize. #MBIMPG2025
September 11, 2025 at 7:24 AM
Thank you!!
Reposted by Ankita Jha
Have you ever thought about inflating tissues?
Or maybe quickly deflating those inflated tissues?
New #EpithelialMechanics pre-print: doi.org/10.1101/2025...
🧵 with pressure control, multiscale buckling, controlled wrinkling
Or maybe quickly deflating those inflated tissues?
New #EpithelialMechanics pre-print: doi.org/10.1101/2025...
🧵 with pressure control, multiscale buckling, controlled wrinkling
July 3, 2025 at 2:23 PM
Have you ever thought about inflating tissues?
Or maybe quickly deflating those inflated tissues?
New #EpithelialMechanics pre-print: doi.org/10.1101/2025...
🧵 with pressure control, multiscale buckling, controlled wrinkling
Or maybe quickly deflating those inflated tissues?
New #EpithelialMechanics pre-print: doi.org/10.1101/2025...
🧵 with pressure control, multiscale buckling, controlled wrinkling
Reposted by Ankita Jha
For today's #FluorescenceFriday I'm thrilled to share that
ScienceAdvances was so nice to pick my picture as this week's featured image!
It's actually a still of a video😊
Check out the paper to learn more
science.org/doi/10.1126/...
#cellbio #devbio #cellmigration #science
Thank you @aaas.org
ScienceAdvances was so nice to pick my picture as this week's featured image!
It's actually a still of a video😊
Check out the paper to learn more
science.org/doi/10.1126/...
#cellbio #devbio #cellmigration #science
Thank you @aaas.org
June 20, 2025 at 4:58 PM
For today's #FluorescenceFriday I'm thrilled to share that
ScienceAdvances was so nice to pick my picture as this week's featured image!
It's actually a still of a video😊
Check out the paper to learn more
science.org/doi/10.1126/...
#cellbio #devbio #cellmigration #science
Thank you @aaas.org
ScienceAdvances was so nice to pick my picture as this week's featured image!
It's actually a still of a video😊
Check out the paper to learn more
science.org/doi/10.1126/...
#cellbio #devbio #cellmigration #science
Thank you @aaas.org
Reposted by Ankita Jha
Our paper is now published! The first encounter of a forming organism with bacteria reveals that innate immunity initiates in epithelial cells of early embryos, even in humans. www.cell.com/cell-host-mi...
made in @ibmb-csic.bsky.social @csic.es @idibell.bsky.social 1/9
made in @ibmb-csic.bsky.social @csic.es @idibell.bsky.social 1/9
June 19, 2025 at 6:27 PM
Our paper is now published! The first encounter of a forming organism with bacteria reveals that innate immunity initiates in epithelial cells of early embryos, even in humans. www.cell.com/cell-host-mi...
made in @ibmb-csic.bsky.social @csic.es @idibell.bsky.social 1/9
made in @ibmb-csic.bsky.social @csic.es @idibell.bsky.social 1/9
So cool to see all these in-vivo examples of cell squeezing
Very excited to share the first preprint from the lab:
www.biorxiv.org/cgi/content/...
We investigated neural crest migration all the way from head to tail of the Zebrafish embryo and we found their nuclei suffer dramatic deformations.
Want to know of they cope with feeling squeezed? 🐟🐠🐟
www.biorxiv.org/cgi/content/...
We investigated neural crest migration all the way from head to tail of the Zebrafish embryo and we found their nuclei suffer dramatic deformations.
Want to know of they cope with feeling squeezed? 🐟🐠🐟
June 10, 2025 at 11:18 AM
So cool to see all these in-vivo examples of cell squeezing
Reposted by Ankita Jha
On Friday, my son stayed home from school because he had a sore throat and wasn’t feeling well. He went with my husband to his office for the morning while I handled our daughter. When he came back at lunch, he was not interested in eating, saying his throat hurt too much. 1/n
May 5, 2025 at 7:11 AM
On Friday, my son stayed home from school because he had a sore throat and wasn’t feeling well. He went with my husband to his office for the morning while I handled our daughter. When he came back at lunch, he was not interested in eating, saying his throat hurt too much. 1/n
So cool
Preprint alert: 🧠🌊🦓-🐟
Have you ever wondered how molecules move around the brain?
Check out our latest preprint led by Halvor Herlyng from the team of Marie Rognes @utropstegn.bsky.social at @simularesearch.bsky.social and us at NTNU.
www.biorxiv.org/content/10.1...
Have you ever wondered how molecules move around the brain?
Check out our latest preprint led by Halvor Herlyng from the team of Marie Rognes @utropstegn.bsky.social at @simularesearch.bsky.social and us at NTNU.
www.biorxiv.org/content/10.1...
Advection versus diffusion in brain ventricular transport
Cerebrospinal fluid (CSF) is integral to brain function. CSF provides mechanical support for the brain and helps distribute nutrients, neurotransmitters and metabolites throughout the central nervous ...
www.biorxiv.org
May 2, 2025 at 7:05 PM
So cool
Reposted by Ankita Jha
Excited to share our discovery www.science.org/doi/10.1126/...
that the #centrosome is prone to breakage!
Using #motile cells, we identify centrosome breakage during #pathfinding, caused by #actin #forces, & prevented by #Dyrk3
Kudos to 1st author Madeleine & thanks to all collaborators!
(1/6)
that the #centrosome is prone to breakage!
Using #motile cells, we identify centrosome breakage during #pathfinding, caused by #actin #forces, & prevented by #Dyrk3
Kudos to 1st author Madeleine & thanks to all collaborators!
(1/6)
April 28, 2025 at 11:51 AM
Excited to share our discovery www.science.org/doi/10.1126/...
that the #centrosome is prone to breakage!
Using #motile cells, we identify centrosome breakage during #pathfinding, caused by #actin #forces, & prevented by #Dyrk3
Kudos to 1st author Madeleine & thanks to all collaborators!
(1/6)
that the #centrosome is prone to breakage!
Using #motile cells, we identify centrosome breakage during #pathfinding, caused by #actin #forces, & prevented by #Dyrk3
Kudos to 1st author Madeleine & thanks to all collaborators!
(1/6)
Time line right now- Science , freeze, more freeze, world around me burning, freeze, visas, science, freeze
April 10, 2025 at 2:27 PM
Time line right now- Science , freeze, more freeze, world around me burning, freeze, visas, science, freeze
Reposted by Ankita Jha
@evapillai.bsky.social and I had fun writing a brief comment www.science.org/doi/10.1126/... (originally featuring an enlightening comparison to a soufflé au fromage that unfortunately disappeared from the final version per Science house style)
Archaea go multicellular under pressure
A microbe from the Dead Sea switches to a tissue-like form when compressed
www.science.org
April 3, 2025 at 6:51 PM
@evapillai.bsky.social and I had fun writing a brief comment www.science.org/doi/10.1126/... (originally featuring an enlightening comparison to a soufflé au fromage that unfortunately disappeared from the final version per Science house style)
Love confinement studies
Read this one!
Read this one!
Pretty much everything is fucked, but here is some beautiful and exciting science from @archaeon-alex.bsky.social and colleagues.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Tissue-like multicellular development triggered by mechanical compression in archaea
The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal mul...
www.science.org
April 4, 2025 at 3:58 AM
Love confinement studies
Read this one!
Read this one!
Reposted by Ankita Jha
Check out this new & exciting #postdoc program from Max Planck Society 🤩 - My lab is thrilled to move to MPI MB in Muenster - positions available in #chromatin #mechanobiology #cancer #stemcells #transcription join us!
🚀 Apply now 🚀
The new Max Planck #Postdoc Program offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops.
postdocprogram.mpg.de
#ScienceCareer #PostdocProgram
The new Max Planck #Postdoc Program offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops.
postdocprogram.mpg.de
#ScienceCareer #PostdocProgram
April 1, 2025 at 5:05 PM
Check out this new & exciting #postdoc program from Max Planck Society 🤩 - My lab is thrilled to move to MPI MB in Muenster - positions available in #chromatin #mechanobiology #cancer #stemcells #transcription join us!
Reposted by Ankita Jha
Excited to share our latest work on how Ca²⁺ regulates actin in cell protrusions—now available as a preprint on bioRxiv! 🎉 Huge congrats to Ernest Iu for leading the project, and a special thanks to our amazing collaborators!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A TRPV4–dependent calcium signaling axis governs lamellipodial actin architecture to promote cell migration
Cell migration is crucial for development and tissue homeostasis, while its dysregulation leads to severe pathologies. Cell migration is driven by the extension of actin–based lamellipodia protrusions...
www.biorxiv.org
March 30, 2025 at 11:41 AM
Excited to share our latest work on how Ca²⁺ regulates actin in cell protrusions—now available as a preprint on bioRxiv! 🎉 Huge congrats to Ernest Iu for leading the project, and a special thanks to our amazing collaborators!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...