Amanda Carr
@amandajcarr.bsky.social
Cell and molecular biologist. Lecturer and PI at UCL Institute of Ophthalmology. Interested in understanding and treating macular diseases
Dear TV show/film editors, if I can’t read the crucial storyline revealing text message on screen without pausing and squinting like a Victorian detective through a magnifying glass, it’s too small. Signed, a frustrated 48-year-old with perfectly respectable glasses. 🤷🏻♀️🤷🏻♀️🤷🏻♀️
a person looking through a magnifying glass with youtube / aapnu cinema written on the bottom
ALT: a person looking through a magnifying glass with youtube / aapnu cinema written on the bottom
media.tenor.com
November 15, 2025 at 11:21 AM
Dear TV show/film editors, if I can’t read the crucial storyline revealing text message on screen without pausing and squinting like a Victorian detective through a magnifying glass, it’s too small. Signed, a frustrated 48-year-old with perfectly respectable glasses. 🤷🏻♀️🤷🏻♀️🤷🏻♀️
Reposted by Amanda Carr
Ok President Trump, if you sue the BBC for $1bn for spreading lies, I’ll sue you for the same amount. I reckon Planet Earth would crowdfund that. Then I’ll buy Mar A Largo, turn it into a climate change research centre, free Melania, and put a 1000% tariff on orange face paint.
November 10, 2025 at 7:29 PM
Ok President Trump, if you sue the BBC for $1bn for spreading lies, I’ll sue you for the same amount. I reckon Planet Earth would crowdfund that. Then I’ll buy Mar A Largo, turn it into a climate change research centre, free Melania, and put a 1000% tariff on orange face paint.
Mornings are for coffee and contemplation 😱 #StrangerThings
November 6, 2025 at 10:24 PM
Mornings are for coffee and contemplation 😱 #StrangerThings
Contrary to my clear instructions, I’d prefer you leave me asleep when you go-go.
Despite stating that I would do anything for love with one important exception, I find ultimately that I would, indeed, do that.
Contrary to all my intentions, I will let the sun go down on me. Tomorrow, most probably.
November 5, 2025 at 7:24 AM
Contrary to my clear instructions, I’d prefer you leave me asleep when you go-go.
Reposted by Amanda Carr
Reposted by Amanda Carr
A team led by @ucleye.bsky.social scientists has identified a key protein that triggers diabetic retinopathy – a condition caused by high blood sugar damaging the retina’s blood vessels and a leading cause of sight loss among working-age adults.
www.ucl.ac.uk/news/2025/oc...
www.ucl.ac.uk/news/2025/oc...
Early trigger of diabetic eye disease identified
A team led by UCL scientists has identified a key protein that triggers diabetic retinopathy – a condition caused by high blood sugar damaging the retina’s blood vessels and a leading cause of sight l...
www.ucl.ac.uk
October 27, 2025 at 3:44 PM
A team led by @ucleye.bsky.social scientists has identified a key protein that triggers diabetic retinopathy – a condition caused by high blood sugar damaging the retina’s blood vessels and a leading cause of sight loss among working-age adults.
www.ucl.ac.uk/news/2025/oc...
www.ucl.ac.uk/news/2025/oc...
Reposted by Amanda Carr
So amazing to see our work on the cover of Science Translational Medicine!!
The new issue of #ScienceTranslationalMedicine is out now!
Mass production of regulatory T cells treats autoimmune disorders in mice, a preclinical study uncovers a promising therapeutic target in diabetic retinopathy, and more. https://scim.ag/3WeFm1R
Mass production of regulatory T cells treats autoimmune disorders in mice, a preclinical study uncovers a promising therapeutic target in diabetic retinopathy, and more. https://scim.ag/3WeFm1R
October 23, 2025 at 10:38 AM
So amazing to see our work on the cover of Science Translational Medicine!!
Reposted by Amanda Carr
A study led by @giuliaderossi.bsky.social has identified a key protein that triggers diabetic retinopathy, a leading cause of blindness. The study, funded by @diabetesuk.bsky.social is published today and featured on the cover of #ScienceTranslationalMedicine.
www.ucl.ac.uk/news/2025/oc...
www.ucl.ac.uk/news/2025/oc...
October 23, 2025 at 1:29 PM
A study led by @giuliaderossi.bsky.social has identified a key protein that triggers diabetic retinopathy, a leading cause of blindness. The study, funded by @diabetesuk.bsky.social is published today and featured on the cover of #ScienceTranslationalMedicine.
www.ucl.ac.uk/news/2025/oc...
www.ucl.ac.uk/news/2025/oc...
As a fully qualified LEGO nerd, this would be my dream Christmas present 🤞🏻
I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...
beta.ideas.lego.com/product-idea...
Biological Laboratory | LEGO® Ideas
This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…
beta.ideas.lego.com
October 17, 2025 at 2:48 PM
As a fully qualified LEGO nerd, this would be my dream Christmas present 🤞🏻
Reposted by Amanda Carr
And so it begins! 🎓 Emily’s PhD journey into shedding light on the fibrotic response in wet AMD. Huge thanks to @macularsociety.org for supporting this talented young scientist, and to @amandajcarr.bsky.social for co-supervising! 👏✨
October 17, 2025 at 1:35 PM
And so it begins! 🎓 Emily’s PhD journey into shedding light on the fibrotic response in wet AMD. Huge thanks to @macularsociety.org for supporting this talented young scientist, and to @amandajcarr.bsky.social for co-supervising! 👏✨
Reposted by Amanda Carr
This #WorldSightDay we share a short film for BBC ideas, in partnership with UKRI, featuring work by 3 @ucleye.bsky.social researchers: PhD student Zaynab Butt, Dr @amandajcarr.bsky.social and pioneering eye researcher Professor Pete Coffey who passed away in June 2025. www.bbc.co.uk/videos/c4gd5...
Can (and should) we cure blindness?
Recent years have seen incredible advances in eyesight restoration. But should we approach blindness as something that needs to be 'cured'? Comedian Tom Skelton, who started losing his sight at 21, ex...
www.bbc.co.uk
October 9, 2025 at 3:56 PM
This #WorldSightDay we share a short film for BBC ideas, in partnership with UKRI, featuring work by 3 @ucleye.bsky.social researchers: PhD student Zaynab Butt, Dr @amandajcarr.bsky.social and pioneering eye researcher Professor Pete Coffey who passed away in June 2025. www.bbc.co.uk/videos/c4gd5...
This completely ruins my old lecture joke “what’s does Jennifer Lopez know about regeneration?” -She used to know a little but she Axolotl 🤓
Hi! Did you know that you aren’t pronouncing axolotl correctly?
Suppression of indigenous languages by the Spanish is one of the Four Wounds of Colonization. This is a small subversion of colonial power you can use!
Axolotl is a Nahuatl word, and it sounds like this:
Suppression of indigenous languages by the Spanish is one of the Four Wounds of Colonization. This is a small subversion of colonial power you can use!
Axolotl is a Nahuatl word, and it sounds like this:
September 29, 2025 at 9:44 PM
This completely ruins my old lecture joke “what’s does Jennifer Lopez know about regeneration?” -She used to know a little but she Axolotl 🤓
Reposted by Amanda Carr
Check this paper from @simonomisz.bsky.social in our lab!
www.biorxiv.org/cgi/content/...
Human retinas/organoids go through 2 apoptotic waves. Organoids also have a necrotic wave. Blocking apoptosis promotes RGC survival to day 200 (usually die!). Apoptosis promotes normal neurogenesis/maturation.
www.biorxiv.org/cgi/content/...
Human retinas/organoids go through 2 apoptotic waves. Organoids also have a necrotic wave. Blocking apoptosis promotes RGC survival to day 200 (usually die!). Apoptosis promotes normal neurogenesis/maturation.
Blocking apoptosis promotes survival and alters developmental dynamics of human retinal ganglion cells in retinal organoids
Retinal ganglion cells (RGCs) are the projection neurons that transmit visual information from the retina to the brain. In many species, a substantial proportion of RGCs are eliminated by programmed c...
www.biorxiv.org
September 29, 2025 at 8:59 PM
Check this paper from @simonomisz.bsky.social in our lab!
www.biorxiv.org/cgi/content/...
Human retinas/organoids go through 2 apoptotic waves. Organoids also have a necrotic wave. Blocking apoptosis promotes RGC survival to day 200 (usually die!). Apoptosis promotes normal neurogenesis/maturation.
www.biorxiv.org/cgi/content/...
Human retinas/organoids go through 2 apoptotic waves. Organoids also have a necrotic wave. Blocking apoptosis promotes RGC survival to day 200 (usually die!). Apoptosis promotes normal neurogenesis/maturation.
Reposted by Amanda Carr
Incredible results from UCL Huntingtons trial show slowing of disease and reduction of NFL after 3 years
www.ucl.ac.uk/news/2025/se...
www.ucl.ac.uk/news/2025/se...
Gene therapy appears to slow Huntington’s disease progression
A global clinical trial for a new Huntington’s disease treatment has posted positive results today, announced by trial sponsor uniQure and UCL scientists.
www.ucl.ac.uk
September 24, 2025 at 10:37 PM
Incredible results from UCL Huntingtons trial show slowing of disease and reduction of NFL after 3 years
www.ucl.ac.uk/news/2025/se...
www.ucl.ac.uk/news/2025/se...
Incredible photo
A picture worth a thousand words.
“None of us have ever done this before. All of this is new, and I just wanted to stand up as American and be seen and make my presence felt.” - 65-year-old Evanston resident Curtis Evans, holding an American flag.
“None of us have ever done this before. All of this is new, and I just wanted to stand up as American and be seen and make my presence felt.” - 65-year-old Evanston resident Curtis Evans, holding an American flag.
At Broadview ICE facility, federal agents hurl tear gas and pepper spray at protesters blocking vans
Federal agents hurled tear gas and pepper spray into a crowd of about 100 protesters who attempted to block vans from entering and exiting a U.S. Immigration and Customs holding facility in Broadvi…
www.chicagotribune.com
September 19, 2025 at 7:50 PM
Incredible photo
Reposted by Amanda Carr
🎉 Groundbreaking sight loss treatment for Leber’s Hereditary Optic Neuropathy now available on NHS England following a successful clinical trial co-led by @ucleye.bsky.social and Moorfields researcher.
Treatment for cause of sight loss approved following UCL research
A novel treatment for Leber’s Hereditary Optic Neuropathy (LHON), a rare genetic disease that can lead to sudden loss of vision, has been approved for NHS patients following a successful clinical…
www.ucl.ac.uk
September 18, 2025 at 2:43 PM
🎉 Groundbreaking sight loss treatment for Leber’s Hereditary Optic Neuropathy now available on NHS England following a successful clinical trial co-led by @ucleye.bsky.social and Moorfields researcher.
Excited to be at the first UK Stem Cell Network in I don’t know how many years, it’s great to see the field get together again. Thanks to Zoe Hewitt from @regenctc.bsky.social for all your efforts getting this going again ❤️
September 16, 2025 at 12:08 PM
Excited to be at the first UK Stem Cell Network in I don’t know how many years, it’s great to see the field get together again. Thanks to Zoe Hewitt from @regenctc.bsky.social for all your efforts getting this going again ❤️
Finally making it through to the @radiohead.wastehq.social queue feels a lot like this….
September 12, 2025 at 9:06 AM
Finally making it through to the @radiohead.wastehq.social queue feels a lot like this….
Reposted by Amanda Carr
Furious American knitters cut off from EU yarn stores sit around fuming surrounded by sharp objects
September 8, 2025 at 4:12 AM
Furious American knitters cut off from EU yarn stores sit around fuming surrounded by sharp objects
Reposted by Amanda Carr
Iconic moment at the Downton Abbey premiere
September 4, 2025 at 6:30 AM
Iconic moment at the Downton Abbey premiere
Reposted by Amanda Carr
The churchyard of Cooling, in Kent, England. Those ten tiny gravestones were made famous by Dickens. They are a nice picture of childhood in a world without vaccines.
September 4, 2025 at 1:02 AM
The churchyard of Cooling, in Kent, England. Those ten tiny gravestones were made famous by Dickens. They are a nice picture of childhood in a world without vaccines.
Reposted by Amanda Carr
A man on the streets of the UK is asked about the “problem of immigration” and dismantles talking points with ease.
September 2, 2025 at 12:42 PM
A man on the streets of the UK is asked about the “problem of immigration” and dismantles talking points with ease.
Reposted by Amanda Carr
An abbreviation (ABB) in a journal article (JA) or Grant Application (GA) is rarely worth the words it saves. Every ABB requires cognitive resources (CR) and at my age by the time I'm halfway through a JA or GA I no longer have the CR to remember what your ABB stood for.
August 15, 2025 at 9:39 AM
An abbreviation (ABB) in a journal article (JA) or Grant Application (GA) is rarely worth the words it saves. Every ABB requires cognitive resources (CR) and at my age by the time I'm halfway through a JA or GA I no longer have the CR to remember what your ABB stood for.
Reposted by Amanda Carr
Scientists who receive NIH funding, anyone want to share your thoughts on the recent White House whiplash? I'm working on a story about it for The Guardian. DMs are open. 🧪
July 30, 2025 at 2:54 PM
Scientists who receive NIH funding, anyone want to share your thoughts on the recent White House whiplash? I'm working on a story about it for The Guardian. DMs are open. 🧪