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aheadofthenerve.bsky.social
(((Dr Hannah Wirtshafter))) 🔬
@aheadofthenerve.bsky.social
1.2K followers 850 following 220 posts
Proud scientist. BRAIN K99/R00. HPC experimental & computational systems neuro. Ephys4life.
Postdoc @NUFeinbergMed w @Disterhoftlab & @SaraASolla.
PhD @MITbiology w/ Matt Wilson
🔬🧠🐀🌈
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aheadofthenerve.bsky.social
(((Dr Hannah Wirtshafter))) 🔬 @aheadofthenerve.bsky.social · Nov 24
🚨 New #Blueprint🚨 Ever wondered how the HPC supports learning across different contexts? My newest, a combo of experimental and comp neuro, w @SaraASolla & @DisterhoftLab, uncovers a 'universal' memory code in the HPC—consistent across animals and environments! 🧵👇
www.biorxiv.org/content/10.1...
A universal hippocampal memory code across animals and environments
How learning is affected by context is a fundamental question of neuroscience, as the ability to generalize learning to different contexts is necessary for navigating the world. An example of swift co...
www.biorxiv.org
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Applications due December 1st!
Come work with us!
November 24, 2025 at 9:41 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
drugmonkey.bsky.social
NIH announces 16% more proposals will be considered for funding! drugmonkey.wordpress.com/2025/11/24/n...
NIH announces 16% more proposals will be considered for funding!
Dudes! It’s good news. LOL. A recent NIH Notice (NOT-OD-26-012) includes the first formal announcement of an expanded triage rate that will be used for the next two rounds (at least) of study…
drugmonkey.wordpress.com
November 24, 2025 at 9:11 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
juangallego.bsky.social
It feels like the converastion about manifold dimensionality is back, so I thought I'd share a paper that explains nicely why measuring the "embedding dimensionality" of a manifold (e.g., counting PCs) can be very different from its actual "intrinsic dimensionality (DoFs)

doi.org/10.1016/j.co...
Redirecting
doi.org
November 24, 2025 at 2:29 AM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
noranewcombe.bsky.social
Thanks to @npr.org for highlighting this story!
www.npr.org/sections/sho...
As funding falters, young brain scientists rethink careers in research
Research on brain disorders may slow as young neuroscientists struggle to find jobs and research grants.
www.npr.org
November 18, 2025 at 12:34 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
aidanhorner.bsky.social
Foraging as an ethological framework for neuroscience

From the amazing @lauragrima.bsky.social and colleagues - definitely looking forward to reading this!

#neuroskyence #psychscisky #cognition
Foraging as an ethological framework for neuroscience
The study of foraging is central to a renewed interest in naturalistic behavior in neuroscience. Applying a foraging framework grounded in behavioral …
www.sciencedirect.com
November 14, 2025 at 9:23 AM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
trackingactions.bsky.social
Want to help shape the SCENE collaboration?! Join us as an executive director: www.cam.ac.uk/jobs/scene-m...
SCENE Manager
The Simons Collaboration on Ecological Neuroscience (SCENE): SCENE is an international consortium of 20 leading researchers in the fields of Computational, Systems and Cognitive Neuroscience, and
www.cam.ac.uk
November 13, 2025 at 5:32 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
annedraelos.bsky.social
Our new paper in @natcomms.nature.com introduces improv, a flexible software platform that integrates models with experiments in real-time. Traditional experiments collect all data first, then analyze it later. With improv, models analyze data as it streams in and actively guide what to do next.
November 13, 2025 at 3:45 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
nitmb.bsky.social
Tomorrow: Samuel Muscinelli, assistant professor of Neurobiology at the University of Chicago, joins us for the NITMB Seminar Series!

You can participate in-person at NITMB or virtually tomorrow at 10am CT
www.nitmb.org/nitmb-semina...
November 13, 2025 at 3:04 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
alt-nihscience4all.altgov.info
Alert for scientists: NIH institute director vacancies are posted! Please apply so we get actual scientists in these positions instead of just political appointees!!!!
jeremymberg.bsky.social Jeremy Berg @jeremymberg.bsky.social · 12d
More new NIH institute and center director positions posted
with a closing date of 11/26/25.

hr.nih.gov/careers/open...

These include the Center for Scientific Review (CSR), National Institute of Nursing Research (NINR), National Institute of Allergy and Infectious Diseases (NIAID), ...

1/3
hr.nih.gov
November 13, 2025 at 3:06 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
cnsmtg.bsky.social
#CNS2026 | Satellite - International Sleep Replay Workshop

Friday, March 6, 2026, 8:00 am - 6:00 pm, Salon F

The workshop is open to all: experience with sleep research is not required. Register here: isrw.bio.uci.edu Registration Deadline, February 15th

@cogneuronews.bsky.social #SleepRelay
Workshops, Socials & Special Events - Cognitive Neuroscience Society
March 7 – 10, 2026 CNS Account CNS 2026 | Workshops, Socials & Special Events   SESSION DATE TIME LOCATION Satellite – International Sleep Replay Workshop Friday, March 6 8:00 am – 6:00 pm Salon F Wor...
www.cogneurosociety.org
November 13, 2025 at 4:21 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
alleninstitute.org
#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel!

📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.

Apply to attend by 12/12: alleninstitute.org/events/aics-...
2026 Lake Conference
Join the Allen Institute for Cell Science and Circuit Neuroscience Basel in Seattle, Washington, April 20–22, 2026, for a 3 day conference, Modeling...
alleninstitute.org
November 13, 2025 at 4:51 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
dangaristo.bsky.social
This is the reality for many grantees at Cornell and elsewhere with frozen grants: after a certain amount of time the loss (in money, research time, or personnel) is unrecoverable.

Paying $60 million doesn't get that all back.
markwilde.bsky.social Mark M. Wilde @markwilde.bsky.social · 17d
Both stop work orders on my two grants have now been released. Unfortunately, the agency for one grant reallocated the funds, so likely those won't come back.

This has gone on for seven months now, and there was no clear point to any of it. I am grateful to colleagues for stepping in to help out.
November 7, 2025 at 8:51 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
aidanhorner.bsky.social
I wrote a thing on episodic memory and systems consolidation. I hope you all enjoy it and/or find it interesting.

A neural state space for episodic memories

www.sciencedirect.com/science/arti...

#neuroskyence #psychscisky #cognition 🧪
A neural state space for episodic memories
Episodic memories are highly dynamic and change in nonlinear ways over time. This dynamism is not captured by existing systems consolidation theories …
www.sciencedirect.com
November 3, 2025 at 12:56 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
nitmb.bsky.social
Statistical Learning in the Wild: Rethinking Discovery in the AI and Data Era

Thank you for joining us at today's NITMB Seminar, featuring @jsb-ucla.bsky.social, Professor and Program Head of the Biostatistics Program at @fredhutch.org!

🎥 Talk recording 🔗 in reply ⬇️
November 7, 2025 at 6:28 PM
aheadofthenerve.bsky.social
can someone say if this is actually setting a precedent for other schools or is a one off/not applicable to other schools?
November 7, 2025 at 4:50 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
cp-neuron.bsky.social
Large sharp-wave ripples promote hippocampo-cortical memory reactivation and consolidation during sleep
Robinson et al. found that the reactivation of experience-related neural ensemble patterns in hippocampus and cortex during sleep is specifically associated with a subset of large SWRs. Closed-loop optogenetic boosting of SWRs during post-task sleep enhanced ensemble reactivation in the hippocampus and prefrontal cortex and improved memory performance in mice.
dlvr.it
November 7, 2025 at 4:24 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
nitmb.bsky.social
Are you a mathematician or biologist curious about the intersection of mathematics in biology?

Our upcoming workshop, Expanding the Palette of Mathematics in Biology, is your opportunity to discover mathematical biology and explore your work in new theoretical ways!

www.nitmb.org/expanding-pa...
November 6, 2025 at 8:30 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
sneuroble.bsky.social
New data showing massive increase in forward funding obligations to R01s as of this summer

More context about the why & disastrous implications here:

www.forbes.com/sites/brucel...

bsky.app/profile/drug...
November 5, 2025 at 6:35 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
noranewcombe.bsky.social
On my lab reading list—
A neural state space for episodic memories: Trends in Cognitive Sciences www.cell.com/trends/cogni...
A neural state space for episodic memories
Episodic memories are highly dynamic and change in nonlinear ways over time. This dynamism is not captured by existing systems consolidation theories that predict a unidirectional process where memories are first supported by the hippocampus and then the neocortex. Here, I propose a 3D state space for episodic memories. The first two dimensions relate to whether episodic retrieval is driven by the hippocampus and the neocortex, critically allowing for independent and additive contributions from both regions. The third dimension relates to the episodic specificity of retrieval. Memories can be located at any point in this state space and move to any other location. The state space captures the dynamic nature of episodic memory and broadens the search space of possible memory states and transformations across time.
www.cell.com
November 4, 2025 at 10:48 AM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
jenna-m-norton.bsky.social
Great article from @virginiagewin.bsky.social showing that across the Federal science ecosystem, research that benefits the American public is being delayed or completely halted, and remaining programs are being consolidated under close partisan political control. www.nature.com/articles/d41...
Dismantling of US federal agencies will ‘destroy science’
From NASA to the National Institutes of Health, federal agencies conduct research that universities cannot. Agency scientists speak out about the irreplaceable facilities, institutional knowledge and ...
www.nature.com
November 4, 2025 at 4:58 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
juangallego.bsky.social
🚨Job alert🚨

The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour

This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"

euraxess.ec.europa.eu/jobs/383909
3 Postdoctoral Research Fellows
Champalimaud Foundation (Fundação D. Anna de Sommer Champalimaud e Dr.
euraxess.ec.europa.eu
November 4, 2025 at 5:11 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
dmcoda.bsky.social
🚨The paper from my postdoc in @graeffjohannes.bsky.social’s lab at @epfl-brainmind.bsky.social is out! We show that memories can be switched on and off by simply changing the « packaging » of DNA in neurons through epigenetic editing. www.nature.com/articles/s41...
Cell-type- and locus-specific epigenetic editing of memory expression - Nature Genetics
CRISPR-based epigenetic editing is used in a cell-type-specific, locus-restricted and temporally controllable manner in the adult mouse brain to modulate memory expression.
www.nature.com
October 29, 2025 at 11:11 AM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
alleninstitute.org
Now accepting paper submissions for the “Neuro for AI & AI for Neuro: Towards Multi-Modal Natural Intelligence” workshop at #AAAI2026!

🔗 https://neuroai-multimodal-workshop.github.io/

@aaai.org
October 30, 2025 at 3:57 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
jeremymberg.bsky.social
Story in Being Patient about Alzheimer's disease funding noting the decrease in the funding of number of new projects due, in part, to the number of multiyear funded grants from the National Institute on Aging.

beingpatient.com/alzheimers-r...
NIH Alzheimer’s Research Funding Is Back — for 49% Fewer Projects
Though the NIH director is calling for $187 million more in funding for Alzheimer’s, the NIH is funding fewer new projects.
beingpatient.com
October 29, 2025 at 5:12 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
kavlifoundation.org
We hope to see you at the 2025 SfN for the BRAIN Initiative Alliance Social: Toolmakers Showcase!

Nov 16, 2025 | 7:00–9:30 PM PT
Hilton Bayfront Sapphire Ballrooms IJMN, San Diego, CA

Register at https://bit.ly/47dPJcn
October 29, 2025 at 3:36 PM